-
1
-
-
80051734611
-
Intrahepatic cholangiocarcinoma: an international multi-institutional analysis of prognostic factors and lymph node assessment
-
de Jong MC, Nathan H, Sotiropoulos GC, et al. Intrahepatic cholangiocarcinoma: an international multi-institutional analysis of prognostic factors and lymph node assessment. J Clin Oncol 2011;29:3140-5.
-
(2011)
J Clin Oncol
, vol.29
, pp. 3140-3145
-
-
de Jong, M.C.1
Nathan, H.2
Sotiropoulos, G.C.3
-
2
-
-
84979895734
-
The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets
-
[Epub ahead of print]
-
Chong DQ, Zhu AX. The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets. Oncotarget 2016. [Epub ahead of print].
-
(2016)
Oncotarget
-
-
Chong, D.Q.1
Zhu, A.X.2
-
3
-
-
85007006685
-
-
2016 Annual Conference. Available online: http://cholangiocarcinoma.org/misc/2016-cholangiocarcinoma-foundation-annual-conference/
-
2016 Annual Conference
-
-
-
4
-
-
84862981935
-
Neoadjuvant therapy and liver transplantation for hilar cholangiocarcinoma: is pretreatment pathological confirmation of diagnosis necessary?
-
discussion 38-40
-
Rosen CB, Darwish Murad S, Heimbach JK, et al. Neoadjuvant therapy and liver transplantation for hilar cholangiocarcinoma: is pretreatment pathological confirmation of diagnosis necessary? J Am Coll Surg 2012;215:31-8; discussion 38-40.
-
(2012)
J Am Coll Surg
, vol.215
, pp. 31-38
-
-
Rosen, C.B.1
Darwish Murad, S.2
Heimbach, J.K.3
-
5
-
-
84863896346
-
Adjuvant therapy in the treatment of biliary tract cancer: a systematic review and meta-analysis
-
Horgan AM, Amir E, Walter T, et al. Adjuvant therapy in the treatment of biliary tract cancer: a systematic review and meta-analysis. J Clin Oncol 2012;30:1934-40.
-
(2012)
J Clin Oncol
, vol.30
, pp. 1934-1940
-
-
Horgan, A.M.1
Amir, E.2
Walter, T.3
-
6
-
-
84919800397
-
Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications
-
Churi CR, Shroff R, Wang Y, et al. Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications. PLoS One 2014;9:e115383.
-
(2014)
PLoS One
, vol.9
-
-
Churi, C.R.1
Shroff, R.2
Wang, Y.3
-
7
-
-
84888353882
-
Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas
-
Jiao Y, Pawlik TM, Anders RA, et al. Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas. Nat Genet 2013;45:1470-3.
-
(2013)
Nat Genet
, vol.45
, pp. 1470-1473
-
-
Jiao, Y.1
Pawlik, T.M.2
Anders, R.A.3
-
8
-
-
84888385562
-
Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers
-
Chan-On W, Nairismägi ML, Ong CK, et al. Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers. Nat Genet 2013;45:1474-8.
-
(2013)
Nat Genet
, vol.45
, pp. 1474-1478
-
-
Chan-On, W.1
Nairismägi, M.L.2
Ong, C.K.3
-
9
-
-
84958754046
-
Multi-Institutional Phase II Study of High-Dose Hypofractionated Proton Beam Therapy in Patients With Localized, Unresectable Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma
-
Hong TS, Wo JY, Yeap BY, et al. Multi-Institutional Phase II Study of High-Dose Hypofractionated Proton Beam Therapy in Patients With Localized, Unresectable Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma. J Clin Oncol 2016;34:460-8.
-
(2016)
J Clin Oncol
, vol.34
, pp. 460-468
-
-
Hong, T.S.1
Wo, J.Y.2
Yeap, B.Y.3
-
10
-
-
84937008885
-
SWOG S0809: A Phase II Intergroup Trial of Adjuvant Capecitabine and Gemcitabine Followed by Radiotherapy and Concurrent Capecitabine in Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma
-
Ben-Josef E, Guthrie KA, El-Khoueiry AB, et al. SWOG S0809: A Phase II Intergroup Trial of Adjuvant Capecitabine and Gemcitabine Followed by Radiotherapy and Concurrent Capecitabine in Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma. J Clin Oncol 2015;33:2617-22.
-
(2015)
J Clin Oncol
, vol.33
, pp. 2617-2622
-
-
Ben-Josef, E.1
Guthrie, K.A.2
El-Khoueiry, A.B.3
-
11
-
-
84971635918
-
Comprehensive genomic profiling of extrahepatic cholangiocarcinoma reveals a long tail of therapeutic targets
-
Lee H, Wang K, Johnson A, et al. Comprehensive genomic profiling of extrahepatic cholangiocarcinoma reveals a long tail of therapeutic targets. J Clin Pathol 2016;69:403-8.
-
(2016)
J Clin Pathol
, vol.69
, pp. 403-408
-
-
Lee, H.1
Wang, K.2
Johnson, A.3
-
12
-
-
84930682337
-
Comprehensive genomic profiling of biliary tract cancers to reveal tumor-specific differences and frequency of clinically relevant genomic alterations
-
Ross JS, Wang K, Javle MM, et al. Comprehensive genomic profiling of biliary tract cancers to reveal tumor-specific differences and frequency of clinically relevant genomic alterations. J Clin Oncol 2015;33:abstr 4009.
-
(2015)
J Clin Oncol
, vol.33
-
-
Ross, J.S.1
Wang, K.2
Javle, M.M.3
-
13
-
-
77950822827
-
Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer
-
Valle J, Wasan H, Palmer DH, et al. Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer. N Engl J Med 2010;362:1273-81.
-
(2010)
N Engl J Med
, vol.362
, pp. 1273-1281
-
-
Valle, J.1
Wasan, H.2
Palmer, D.H.3
-
14
-
-
84940656195
-
Prognosis and Clinicopathologic Features of Patients With Advanced Stage Isocitrate Dehydrogenase (IDH) Mutant and IDH Wild-Type Intrahepatic Cholangiocarcinoma
-
Goyal L, Govindan A, Sheth RA, et al. Prognosis and Clinicopathologic Features of Patients With Advanced Stage Isocitrate Dehydrogenase (IDH) Mutant and IDH Wild-Type Intrahepatic Cholangiocarcinoma. Oncologist 2015;20:1019-27.
-
(2015)
Oncologist
, vol.20
, pp. 1019-1027
-
-
Goyal, L.1
Govindan, A.2
Sheth, R.A.3
-
15
-
-
84893354743
-
Cisplatin and gemcitabine for advanced biliary tract cancer: a meta-analysis of two randomised trials
-
Valle JW, Furuse J, Jitlal M, et al. Cisplatin and gemcitabine for advanced biliary tract cancer: a meta-analysis of two randomised trials. Ann Oncol 2014;25:391-8.
-
(2014)
Ann Oncol
, vol.25
, pp. 391-398
-
-
Valle, J.W.1
Furuse, J.2
Jitlal, M.3
-
16
-
-
78649581706
-
Cetuximab, gemcitabine, and oxaliplatin in patients with unresectable advanced or metastatic biliary tract cancer: a phase 2 study
-
Gruenberger B, Schueller J, Heubrandtner U, et al. Cetuximab, gemcitabine, and oxaliplatin in patients with unresectable advanced or metastatic biliary tract cancer: a phase 2 study. Lancet Oncol 2010;11:1142-8.
-
(2010)
Lancet Oncol
, vol.11
, pp. 1142-1148
-
-
Gruenberger, B.1
Schueller, J.2
Heubrandtner, U.3
-
17
-
-
84903537674
-
Gemcitabine and oxaliplatin with or without cetuximab in advanced biliary-tract cancer (BINGO): a randomised, open-label, non-comparative phase 2 trial
-
Malka D, Cervera P, Foulon S, et al. Gemcitabine and oxaliplatin with or without cetuximab in advanced biliary-tract cancer (BINGO): a randomised, open-label, non-comparative phase 2 trial. Lancet Oncol 2014;15:819-28.
-
(2014)
Lancet Oncol
, vol.15
, pp. 819-828
-
-
Malka, D.1
Cervera, P.2
Foulon, S.3
-
18
-
-
84887994567
-
KRAS mutation status-stratified randomized phase II trial of GEMOX with and without cetuximab in advanced biliary tract cancer (ABTC): The TCOG T1210 trial
-
Chen LT, Chen JS, Chao Y, et al. KRAS mutation status-stratified randomized phase II trial of GEMOX with and without cetuximab in advanced biliary tract cancer (ABTC): The TCOG T1210 trial. J Clin Oncol 2013;31:abstr 4018.
-
(2013)
J Clin Oncol
, vol.31
-
-
Chen, L.T.1
Chen, J.S.2
Chao, Y.3
-
19
-
-
84856476387
-
Gemcitabine and oxaliplatin with or without erlotinib in advanced biliary-tract cancer: a multicentre, open-label, randomised, phase 3 study
-
Lee J, Park SH, Chang HM, et al. Gemcitabine and oxaliplatin with or without erlotinib in advanced biliary-tract cancer: a multicentre, open-label, randomised, phase 3 study. Lancet Oncol 2012;13:181-8.
-
(2012)
Lancet Oncol
, vol.13
, pp. 181-188
-
-
Lee, J.1
Park, S.H.2
Chang, H.M.3
-
20
-
-
84959159986
-
Panitumumab in combination with gemcitabine and oxaliplatin does not prolong survival in wild-type KRAS advanced biliary tract cancer: A randomized phase 2 trial (Vecti-BIL study)
-
Leone F, Marino D, Cereda S, et al. Panitumumab in combination with gemcitabine and oxaliplatin does not prolong survival in wild-type KRAS advanced biliary tract cancer: A randomized phase 2 trial (Vecti-BIL study). Cancer 2016;122:574-81.
-
(2016)
Cancer
, vol.122
, pp. 574-581
-
-
Leone, F.1
Marino, D.2
Cereda, S.3
-
21
-
-
77955285782
-
Genetics of biliary tract cancers and emerging targeted therapies
-
Hezel AF, Deshpande V, Zhu AX. Genetics of biliary tract cancers and emerging targeted therapies. J Clin Oncol 2010;28:3531-40.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3531-3540
-
-
Hezel, A.F.1
Deshpande, V.2
Zhu, A.X.3
-
22
-
-
84896457874
-
New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing
-
Ross JS, Wang K, Gay L, et al. New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing. Oncologist 2014;19:235-42.
-
(2014)
Oncologist
, vol.19
, pp. 235-242
-
-
Ross, J.S.1
Wang, K.2
Gay, L.3
-
23
-
-
84968828480
-
The first reported results of AG-120, a first-in-class, potent inhibitor of the IDH1 mutant protein, in a Phase I study of patients with advanced IDH1-mutant solid tumors, including gliomas
-
Burris H, Mellinghoff IK, Maher E, et al. The first reported results of AG-120, a first-in-class, potent inhibitor of the IDH1 mutant protein, in a Phase I study of patients with advanced IDH1-mutant solid tumors, including gliomas. Molecular Targets and Cancer Therapeutics 2015:5-9.
-
(2015)
Molecular Targets and Cancer Therapeutics
, pp. 5-9
-
-
Burris, H.1
Mellinghoff, I.K.2
Maher, E.3
-
24
-
-
85009846139
-
A phase 2 study of BGJ398 in patients (pts) with advanced or metastatic FGFR-altered cholangiocarcinoma (CCA) who failed or are intolerant to platinum-based chemotherapy
-
Javle MM, Shroff RT, Zhu A, et al. A phase 2 study of BGJ398 in patients (pts) with advanced or metastatic FGFR-altered cholangiocarcinoma (CCA) who failed or are intolerant to platinum-based chemotherapy. J Clin Oncol 2016;34:abstr 335.
-
(2016)
J Clin Oncol
, vol.34
-
-
Javle, M.M.1
Shroff, R.T.2
Zhu, A.3
-
25
-
-
84998639474
-
525 Safety and efficacy of pembrolizumab (MK-3475) in patients (pts) with advanced biliary tract cancer: Interim results of KEYNOTE-028
-
Bang YJ, Doi T, De Braud F, et al. 525 Safety and efficacy of pembrolizumab (MK-3475) in patients (pts) with advanced biliary tract cancer: Interim results of KEYNOTE-028. Eur J Cancer 2015:S112.
-
(2015)
Eur J Cancer
, pp. S112
-
-
Bang, Y.J.1
Doi, T.2
De Braud, F.3
-
26
-
-
84940556535
-
Genomic spectra of biliary tract cancer
-
Nakamura H, Arai Y, Totoki Y, et al. Genomic spectra of biliary tract cancer. Nat Genet 2015;47:1003-10.
-
(2015)
Nat Genet
, vol.47
, pp. 1003-1010
-
-
Nakamura, H.1
Arai, Y.2
Totoki, Y.3
-
28
-
-
84948783235
-
Immunotherapy in hepatocellular carcinoma: Primed to make a difference?
-
Harding JJ, El Dika I, Abou-Alfa GK. Immunotherapy in hepatocellular carcinoma: Primed to make a difference? Cancer 2016;122:367-77.
-
(2016)
Cancer
, vol.122
, pp. 367-377
-
-
Harding, J.J.1
El Dika, I.2
Abou-Alfa, G.K.3
-
29
-
-
84964575631
-
A Hippo and Fibroblast Growth Factor Receptor Autocrine Pathway in Cholangiocarcinoma
-
Rizvi S, Yamada D, Hirsova P, et al. A Hippo and Fibroblast Growth Factor Receptor Autocrine Pathway in Cholangiocarcinoma. J Biol Chem 2016;291:8031-47.
-
(2016)
J Biol Chem
, vol.291
, pp. 8031-8047
-
-
Rizvi, S.1
Yamada, D.2
Hirsova, P.3
-
30
-
-
84905993872
-
Platelet-derived growth factor primes cancer-associated fibroblasts for apoptosis
-
Rizvi S, Mertens JC, Bronk SF, et al. Platelet-derived growth factor primes cancer-associated fibroblasts for apoptosis. J Biol Chem 2014;289:22835-49.
-
(2014)
J Biol Chem
, vol.289
, pp. 22835-22849
-
-
Rizvi, S.1
Mertens, J.C.2
Bronk, S.F.3
-
31
-
-
84864773126
-
Cholangiocarcinomas can originate from hepatocytes in mice
-
Fan B, Malato Y, Calvisi DF, et al. Cholangiocarcinomas can originate from hepatocytes in mice. J Clin Invest 2012;122:2911-5.
-
(2012)
J Clin Invest
, vol.122
, pp. 2911-2915
-
-
Fan, B.1
Malato, Y.2
Calvisi, D.F.3
-
32
-
-
84868625552
-
Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes
-
Sekiya S, Suzuki A. Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes. J Clin Invest 2012;122:3914-8.
-
(2012)
J Clin Invest
, vol.122
, pp. 3914-3918
-
-
Sekiya, S.1
Suzuki, A.2
-
33
-
-
84894229721
-
Cell lineage tracing reveals a biliary origin of intrahepatic cholangiocarcinoma
-
Guest RV, Boulter L, Kendall TJ, et al. Cell lineage tracing reveals a biliary origin of intrahepatic cholangiocarcinoma. Cancer Res 2014;74:1005-10.
-
(2014)
Cancer Res
, vol.74
, pp. 1005-1010
-
-
Guest, R.V.1
Boulter, L.2
Kendall, T.J.3
-
34
-
-
84907033777
-
Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer
-
Saha SK, Parachoniak CA, Ghanta KS, et al. Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer. Nature 2014;513:110-4.
-
(2014)
Nature
, vol.513
, pp. 110-114
-
-
Saha, S.K.1
Parachoniak, C.A.2
Ghanta, K.S.3
-
35
-
-
84929292324
-
Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma
-
Sia D, Losic B, Moeini A, et al. Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma. Nat Commun 2015;6:6087.
-
(2015)
Nat Commun
, vol.6
, pp. 6087
-
-
Sia, D.1
Losic, B.2
Moeini, A.3
-
36
-
-
84863279150
-
Suppression of hepatocyte proliferation by hepatocyte nuclear factor 4α in adult mice
-
Bonzo JA, Ferry CH, Matsubara T, et al. Suppression of hepatocyte proliferation by hepatocyte nuclear factor 4α in adult mice. J Biol Chem 2012;287:7345-56.
-
(2012)
J Biol Chem
, vol.287
, pp. 7345-7356
-
-
Bonzo, J.A.1
Ferry, C.H.2
Matsubara, T.3
-
37
-
-
84924043490
-
WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited
-
Boulter L, Guest RV, Kendall TJ, et al. WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited. J Clin Invest 2015;125:1269-85.
-
(2015)
J Clin Invest
, vol.125
, pp. 1269-1285
-
-
Boulter, L.1
Guest, R.V.2
Kendall, T.J.3
-
38
-
-
84879125455
-
Hepatocyte nuclear factor 4 alpha deletion promotes diethylnitrosamine-induced hepatocellular carcinoma in rodents
-
Walesky C, Edwards G, Borude P, et al. Hepatocyte nuclear factor 4 alpha deletion promotes diethylnitrosamine-induced hepatocellular carcinoma in rodents. Hepatology 2013;57:2480-90.
-
(2013)
Hepatology
, vol.57
, pp. 2480-2490
-
-
Walesky, C.1
Edwards, G.2
Borude, P.3
-
39
-
-
84871876340
-
Hepatocyte-specific deletion of hepatocyte nuclear factor-4α in adult mice results in increased hepatocyte proliferation
-
Walesky C, Gunewardena S, Terwilliger EF, et al. Hepatocyte-specific deletion of hepatocyte nuclear factor-4α in adult mice results in increased hepatocyte proliferation. Am J Physiol Gastrointest Liver Physiol 2013;304:G26-37.
-
(2013)
Am J Physiol Gastrointest Liver Physiol
, vol.304
, pp. G26-G37
-
-
Walesky, C.1
Gunewardena, S.2
Terwilliger, E.F.3
-
40
-
-
84856191525
-
Dysregulation of Wnt/β-catenin signaling in gastrointestinal cancers
-
White BD, Chien AJ, Dawson DW. Dysregulation of Wnt/β-catenin signaling in gastrointestinal cancers. Gastroenterology 2012;142:219-32.
-
(2012)
Gastroenterology
, vol.142
, pp. 219-232
-
-
White, B.D.1
Chien, A.J.2
Dawson, D.W.3
|