Uric acid crystals induce placental inflammation and alter trophoblast function via an IL-1-dependent pathway: Implications for fetal growth restriction

Journal of Immunology

Volumn 198, Issue 1, 2017, Pages 443-451

  Brien, Marie Eve ^a,b   Duval, Cyntia ^a,b   Palacios, Julia ^a,b   Boufaied, Ines ^a,b   Hudon Thibeault, Andrée Anne ^c   Nadeau Vallée, Mathieu ^a,b   Vaillancourt, Cathy ^c   Sibley, Colin P ^d,e   Abrahams, Vikki M ^f   Jones, Rebecca L ^d,e   Girard, Sylvie ^a,b  

^a UNIVERSITY OF MONTREAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c INRS INSTITUT ARMAND FRAPPIER   (Canada)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e ST MARY S HOSPITAL   (United Kingdom)

^f YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; URATE; URIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOTROPHOBLAST; DISEASE ASSOCIATION; EXPLANT; FEMALE; FETUS; GESTATION PERIOD; INTRAUTERINE GROWTH RETARDATION; NONHUMAN; PLACENTA DISORDER; PLACENTAL INFLAMMATION; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SYNCYTIOTROPHOBLAST; TROPHOBLAST; ANIMAL; CHORIOAMNIONITIS; DISEASE MODEL; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNOLOGY; PATHOLOGY; PREGNANCY; SPRAGUE DAWLEY RAT;

ANIMALS; CHORIOAMNIONITIS; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FETAL GROWTH RETARDATION; HUMANS; INTERLEUKIN-1; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; TROPHOBLASTS; URIC ACID;

EID: 85006992568     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1601179     Document Type: Article

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