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Volumn 3, Issue 1, 2015, Pages

In vivo creatine kinase reaction kinetics at rest and stress in type II diabetic rat heart

Author keywords

31P; Creatine kinase flux; Diabetic cardiomyopathy; Heart; Type II diabetes

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE KINASE MB; CREATINE PHOSPHATE; DOBUTAMINE;

EID: 85006826464     PISSN: None     EISSN: 2051817X     Source Type: Journal    
DOI: 10.14814/phy2.12248     Document Type: Article
Times cited : (12)

References (54)
  • 1
    • 0021373065 scopus 로고
    • NMR studies of enzymatic rates in vitro and in vivo by magnetization transfer. Q
    • Alger, J. R., and R. G. Shulman. 1984. NMR studies of enzymatic rates in vitro and in vivo by magnetization transfer. Q. Rev. Biophys. 17:83-124.
    • (1984) Rev. Biophys , vol.17 , pp. 83-124
    • Alger, J.R.1    Shulman, R.G.2
  • 2
    • 0025302695 scopus 로고
    • Isoenzyme profiles of creatine kinase, lactate dehydrogenase, and aspartate aminotransferase in the diabetic heart: Comparison with hereditary and catecholamine cardiomyopathies.
    • Awaji, Y., H. Hashimoto, Y. Matsui, K. Kawaguchi, K. Okumura, T. Ito, et al. 1990. Isoenzyme profiles of creatine kinase, lactate dehydrogenase, and aspartate aminotransferase in the diabetic heart: comparison with hereditary and catecholamine cardiomyopathies. Cardiovasc. Res. 24:547-554.
    • (1990) Cardiovasc. Res , vol.24 , pp. 547-554
    • Awaji, Y.1    Hashimoto, H.2    Matsui, Y.3    Kawaguchi, K.4    Okumura, K.5    Ito, T.6
  • 3
    • 84899931981 scopus 로고    scopus 로고
    • Reproducibility of creatine kinase reaction kinetics in human heart: A (31) P time-dependent saturation transfer spectroscopy study
    • Bashir, A., and R. Gropler. 2014. Reproducibility of creatine kinase reaction kinetics in human heart: a (31) P time-dependent saturation transfer spectroscopy study. NMR Biomed. 27:663-671.
    • (2014) NMR Biomed , vol.27 , pp. 663-671
    • Bashir, A.1    Gropler, R.2
  • 4
    • 0037010011 scopus 로고    scopus 로고
    • Absolute concentrations of high-energy phosphate metabolites in normal, hypertrophied, and failing human myocardium measured noninvasively with (31)P-SLOOP magnetic resonance spectroscopy
    • Beer, M., T. Seyfarth, J. Sandstede, W. Landschutz, C. Lipke, H. Kostler, et al. 2002. Absolute concentrations of high-energy phosphate metabolites in normal, hypertrophied, and failing human myocardium measured noninvasively with (31)P-SLOOP magnetic resonance spectroscopy. J. Am. Coll. Cardiol. 40:1267-1274.
    • (2002) J. Am. Coll. Cardiol , vol.40 , pp. 1267-1274
    • Beer, M.1    Seyfarth, T.2    Sandstede, J.3    Landschutz, W.4    Lipke, C.5    Kostler, H.6
  • 5
    • 0141669148 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy
    • Bell, D. S. 2003. Diabetic cardiomyopathy. Diabetes Care 26:2949-2951.
    • (2003) Diabetes Care , vol.26 , pp. 2949-2951
    • Bell, D.S.1
  • 6
    • 0022003591 scopus 로고
    • Reaction rates of creatine kinase and ATP synthesis in the isolated rat heart. A 31P NMR magnetization transfer study
    • Bittl, J. A., and J. S. Ingwall. 1985. Reaction rates of creatine kinase and ATP synthesis in the isolated rat heart. A 31P NMR magnetization transfer study. J. Biol. Chem. 260:3512-3517.
    • (1985) J. Biol. Chem , vol.260 , pp. 3512-3517
    • Bittl, J.A.1    Ingwall, J.S.2
  • 7
    • 27444441492 scopus 로고    scopus 로고
    • Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity
    • Boudina, S., S. Sena, B. T. O’Neill, P. Tathireddy, M. E. Young, and E. D. Abel. 2005. Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity. Circulation 112:2686-2695.
    • (2005) Circulation , vol.112 , pp. 2686-2695
    • Boudina, S.1    Sena, S.2    O’Neill, B.T.3    Tathireddy, P.4    Young, M.E.5    Abel, E.D.6
  • 9
    • 79955469177 scopus 로고    scopus 로고
    • Cardiovascular outcomes in framingham participants with diabetes: The importance of blood pressure
    • Chen, G., F. A. McAlister, R. L. Walker, B. R. Hemmelgarn, and N. R. Campbell. 2011. Cardiovascular outcomes in framingham participants with diabetes: the importance of blood pressure. Hypertension 57:891-897.
    • (2011) Hypertension , vol.57 , pp. 891-897
    • Chen, G.1    McAlister, F.A.2    Walker, R.L.3    Hemmelgarn, B.R.4    Campbell, N.R.5
  • 10
    • 0344874204 scopus 로고    scopus 로고
    • Left ventricular diastolic dysfunction: An early sign of diabetic cardiomyopathy?
    • Cosson, S., and J. P. Kevorkian. 2003. Left ventricular diastolic dysfunction: an early sign of diabetic cardiomyopathy? Diabetes Metabol. 29:455-466.
    • (2003) Diabetes Metabol , vol.29 , pp. 455-466
    • Cosson, S.1    Kevorkian, J.P.2
  • 11
    • 84856193298 scopus 로고    scopus 로고
    • Long-term severe diabetes only leads to mild cardiac diastolic dysfunction in Zucker diabetic fatty rats
    • Daniels, A., D. Linz, M. van Bilsen, H. Rutten, T. Sadowski, S. Ruf, et al. 2012. Long-term severe diabetes only leads to mild cardiac diastolic dysfunction in Zucker diabetic fatty rats. Eur. J. Heart Fail. 14:193-201.
    • (2012) Eur. J. Heart Fail , vol.14 , pp. 193-201
    • Daniels, A.1    Linz, D.2    Van Bilsen, M.3    Rutten, H.4    Sadowski, T.5    Ruf, S.6
  • 12
    • 0038488294 scopus 로고    scopus 로고
    • Diastolic dysfunction is associated with altered myocardial metabolism in asymptomatic normotensive patients with well-controlled type 2 diabetes mellitus
    • Diamant, M., H. J. Lamb, Y. Groeneveld, E. L. Endert, J. W. Smit, J. J. Bax, et al. 2003. Diastolic dysfunction is associated with altered myocardial metabolism in asymptomatic normotensive patients with well-controlled type 2 diabetes mellitus. J. Am. Coll. Cardiol. 42:328-335.
    • (2003) J. Am. Coll. Cardiol , vol.42 , pp. 328-335
    • Diamant, M.1    Lamb, H.J.2    Groeneveld, Y.3    Endert, E.L.4    Smit, J.W.5    Bax, J.J.6
  • 13
    • 0027957350 scopus 로고
    • The metabolic consequences of an increase in the frequency of stimulation in isolated ferret hearts
    • Elliott, A. C., G. L. Smith, and D. G. Allen. 1994. The metabolic consequences of an increase in the frequency of stimulation in isolated ferret hearts. J. Physiol. 474:147-159.
    • (1994) J. Physiol , vol.474 , pp. 147-159
    • Elliott, A.C.1    Smith, G.L.2    Allen, D.G.3
  • 14
    • 84885948700 scopus 로고    scopus 로고
    • Quantification of human high-energy phosphate metabolite concentrations at 3 T with partial volume and sensitivity corrections
    • El-Sharkawy, A. M., R. E. Gabr, M. Schar, R. G. Weiss, and P. A. Bottomley. 2013. Quantification of human high-energy phosphate metabolite concentrations at 3 T with partial volume and sensitivity corrections. NMR Biomed. 26: 1363-1371.
    • (2013) NMR Biomed , vol.26 , pp. 1363-1371
    • El-Sharkawy, A.M.1    Gabr, R.E.2    Schar, M.3    Weiss, R.G.4    Bottomley, P.A.5
  • 15
    • 4143140134 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy: Evidence, mechanisms, and therapeutic implications. Endocr
    • Fang, Z. Y., J. B. Prins, and T. H. Marwick. 2004. Diabetic cardiomyopathy: evidence, mechanisms, and therapeutic implications. Endocr. Rev. 25:543-567.
    • (2004) Rev , vol.25 , pp. 543-567
    • Fang, Z.Y.1    Prins, J.B.2    Marwick, T.H.3
  • 16
    • 0026099165 scopus 로고
    • Regulation of expression of M, B, and mitochondrial creatine kinase mRNAs in the left ventricle after pressure overload in rats.
    • Fontanet, H. L., R. V. Trask, R. C. Haas, A. W. Strauss, D. R. Abendschein, and J. J. Billadello. 1991. Regulation of expression of M, B, and mitochondrial creatine kinase mRNAs in the left ventricle after pressure overload in rats. Circ. Res. 68:1007-1012.
    • (1991) Circ. Res , vol.68 , pp. 1007-1012
    • Fontanet, H.L.1    Trask, R.V.2    Haas, R.C.3    Strauss, A.W.4    Abendschein, D.R.5    Billadello, J.J.6
  • 17
    • 0842283309 scopus 로고    scopus 로고
    • Myocardial hypertrophy and enhanced left ventricular contractility in Zucker diabetic fatty rats.
    • Fredersdorf, S., C. Thumann, C. Ulucan, D. P. Griese, A. Luchner, G. A. Riegger, et al. 2004. Myocardial hypertrophy and enhanced left ventricular contractility in Zucker diabetic fatty rats. Cardiovasc. Pathol. 13:11-19.
    • (2004) Cardiovasc. Pathol. , vol.13 , pp. 11-19
    • Fredersdorf, S.1    Thumann, C.2    Ulucan, C.3    Griese, D.P.4    Luchner, A.5    Riegger, G.A.6
  • 19
    • 0032560807 scopus 로고    scopus 로고
    • Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction
    • Haffner, S. M., S. Lehto, T. Ronnemaa, K. Pyorala, and M. Laakso. 1998. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N. Engl. J. Med. 339:229-234.
    • (1998) N. Engl. J. Med , vol.339 , pp. 229-234
    • Haffner, S.M.1    Lehto, S.2    Ronnemaa, T.3    Pyorala, K.4    Laakso, M.5
  • 20
    • 33745332086 scopus 로고    scopus 로고
    • Correlation between myocardial contractile force and cytosolic inorganic phosphate during early ischemia
    • He, M. X., S. Wang, and H. F. Downey. 1997. Correlation between myocardial contractile force and cytosolic inorganic phosphate during early ischemia. Am. J. Physiol. 272: H1333-H1341.
    • (1997) Am. J. Physiol , vol.272 , pp. H1333-H1341
    • He, M.X.1    Wang, S.2    Downey, H.F.3
  • 21
    • 0034880608 scopus 로고    scopus 로고
    • 31P NMR quantitation of phosphorus metabolites in rat heart and skeletal muscle in vivo
    • Hitchins, S., J. M. Cieslar, and G. P. Dobson. 2001. 31P NMR quantitation of phosphorus metabolites in rat heart and skeletal muscle in vivo. Am. J. Physiol. Heart Circ. Physiol. 281:H882-H887.
    • (2001) Am. J. Physiol. Heart Circ. Physiol , vol.281 , pp. H882-H887
    • Hitchins, S.1    Cieslar, J.M.2    Dobson, G.P.3
  • 22
    • 0036750019 scopus 로고    scopus 로고
    • Is creatine kinase a target for AMP-activated protein kinase in the heart
    • Ingwall, J. S. 2002. Is creatine kinase a target for AMP-activated protein kinase in the heart? J. Mol. Cell. Cardiol. 34:1111-1120.
    • (2002) J. Mol. Cell. Cardiol , vol.34 , pp. 1111-1120
    • Ingwall, J.S.1
  • 23
    • 59449085388 scopus 로고    scopus 로고
    • Energy metabolism in heart failure and remodelling.
    • Ingwall, J. S. 2009. Energy metabolism in heart failure and remodelling. Cardiovasc. Res. 81:412-419.
    • (2009) Cardiovasc. Res , vol.81 , pp. 412-419
    • Ingwall, J.S.1
  • 24
    • 54249100885 scopus 로고    scopus 로고
    • Potassium fluxes, energy metabolism, and oxygenation in intact diabetic rat hearts under normal and stress conditions
    • Jilkina, O., B. Kuzio, and V. V. Kupriyanov. 2008. Potassium fluxes, energy metabolism, and oxygenation in intact diabetic rat hearts under normal and stress conditions. Can. J. Physiol. Pharmacol. 86:710-725.
    • (2008) Can. J. Physiol. Pharmacol , vol.86 , pp. 710-725
    • Jilkina, O.1    Kuzio, B.2    Kupriyanov, V.V.3
  • 25
    • 34848924909 scopus 로고    scopus 로고
    • Absolute quantification of phosphorus metabolite concentrations in human muscle in vivo by 31P MRS: A quantitative review
    • Kemp, G. J., M. Meyerspeer, and E. Moser. 2007. Absolute quantification of phosphorus metabolite concentrations in human muscle in vivo by 31P MRS: a quantitative review. NMR Biomed. 20:555-565.
    • (2007) NMR Biomed , vol.20 , pp. 555-565
    • Kemp, G.J.1    Meyerspeer, M.2    Moser, E.3
  • 26
    • 0024828828 scopus 로고
    • Alterations in the creatine kinase system in the myocardium of cardiomyopathic hamsters. Biochem. Biophys. Res
    • Khuchua, Z. A., R. Ventura-Clapier, A. V. Kuznetsov, M. N. Grishin, and V. A. Saks. 1989. Alterations in the creatine kinase system in the myocardium of cardiomyopathic hamsters. Biochem. Biophys. Res. Commun. 165:748-757.
    • (1989) Commun , vol.165 , pp. 748-757
    • Khuchua, Z.A.1    Ventura-Clapier, R.2    Kuznetsov, A.V.3    Grishin, M.N.4    Saks, V.A.5
  • 27
    • 0025440629 scopus 로고
    • Spin-exchange NMR spectroscopy in studies of the kinetics of enzymes and membrane transport
    • Kuchel, P. W. 1990. Spin-exchange NMR spectroscopy in studies of the kinetics of enzymes and membrane transport. NMR Biomed. 3:102-119.
    • (1990) NMR Biomed , vol.3 , pp. 102-119
    • Kuchel, P.W.1
  • 28
    • 0020626828 scopus 로고
    • Defective oxidative metabolism of heart mitochondria from genetically diabetic mice
    • Kuo, T. H., K. H. Moore, F. Giacomelli, and J. Wiener. 1983. Defective oxidative metabolism of heart mitochondria from genetically diabetic mice. Diabetes 32:781-787.
    • (1983) Diabetes , vol.32 , pp. 781-787
    • Kuo, T.H.1    Moore, K.H.2    Giacomelli, F.3    Wiener, J.4
  • 29
    • 0021921144 scopus 로고
    • Oxidative metabolism of Polytron versus Nagarse mitochondria in hearts of genetically diabetic mice.
    • Kuo, T. H., F. Giacomelli, and J. Wiener. 1985. Oxidative metabolism of Polytron versus Nagarse mitochondria in hearts of genetically diabetic mice. Biochim. Biophys. Acta 806:9-15.
    • (1985) Biochim. Biophys. Acta , vol.806 , pp. 9-15
    • Kuo, T.H.1    Giacomelli, F.2    Wiener, J.3
  • 30
    • 58149522335 scopus 로고    scopus 로고
    • Regulation of muscle creatine kinase by phosphorylation in normal and diabetic hearts.
    • Lin, G., Y. Liu, and K. M. MacLeod. 2009. Regulation of muscle creatine kinase by phosphorylation in normal and diabetic hearts. Cell. Mol. Life Sci. 66:135-144.
    • (2009) Cell. Mol. Life Sci , vol.66 , pp. 135-144
    • Lin, G.1    Liu, Y.2    Macleod, K.M.3
  • 31
    • 0035471021 scopus 로고    scopus 로고
    • Mitochondrial creatine kinase: Properties and function
    • Lipskaya, T. Y. 2001. Mitochondrial creatine kinase: properties and function. Biochemistry (Mosc) 66:1098-1111.
    • (2001) Biochemistry (Mosc) , vol.66 , pp. 1098-1111
    • Lipskaya, T.Y.1
  • 34
    • 0019981564 scopus 로고
    • Isoenzyme pattern and activity of myocardial creatine phosphokinase under heart adaptation to prolonged overload.
    • Meerson, F. Z., and M. P. Javich. 1982. Isoenzyme pattern and activity of myocardial creatine phosphokinase under heart adaptation to prolonged overload. Basic Res. Cardiol. 77:349-358.
    • (1982) Basic Res. Cardiol , vol.77 , pp. 349-358
    • Meerson, F.Z.1    Javich, M.P.2
  • 36
    • 84876569165 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy: Pathophysiology and clinical features.
    • Miki, T., S. Yuda, H. Kouzu, and T. Miura. 2013. Diabetic cardiomyopathy: pathophysiology and clinical features. Heart Fail. Rev. 18:149-166.
    • (2013) Heart Fail. Rev , vol.18 , pp. 149-166
    • Miki, T.1    Yuda, S.2    Kouzu, H.3    Miura, T.4
  • 37
    • 0034989141 scopus 로고    scopus 로고
    • Java-based graphical user interface for the MRUI quantitation package
    • Naressi, A., C. Couturier, J. M. Devos, M. Janssen, C. Mangeat, R. de Beer, et al. 2001. Java-based graphical user interface for the MRUI quantitation package. MAGMA 12:141-152.
    • (2001) MAGMA , vol.12 , pp. 141-152
    • Naressi, A.1    Couturier, C.2    Devos, J.M.3    Janssen, M.4    Mangeat, C.5    De Beer, R.6
  • 39
    • 0033511113 scopus 로고    scopus 로고
    • High-energy phosphate metabolism in normal, hypertrophied and failing human myocardium.
    • Neubauer, S. 1999. High-energy phosphate metabolism in normal, hypertrophied and failing human myocardium. Heart Fail. Rev. 4:269-280.
    • (1999) Heart Fail. Rev , vol.4 , pp. 269-280
    • Neubauer, S.1
  • 40
    • 0024460878 scopus 로고
    • Ventricular myosin and creatine-kinase isoenzymes in hypertensive rats treated with captopril
    • Pauletto, P., L. Nascimben, D. Piccolo, S. Secchiero, G. Vescovo, G. Scannapieco, et al. 1989. Ventricular myosin and creatine-kinase isoenzymes in hypertensive rats treated with captopril. Hypertension 14:556-562.
    • (1989) Hypertension , vol.14 , pp. 556-562
    • Pauletto, P.1    Nascimben, L.2    Piccolo, D.3    Secchiero, S.4    Vescovo, G.5    Scannapieco, G.6
  • 41
    • 0024432530 scopus 로고
    • Diabetes decreases creatine kinase enzyme activity and mRNA level in the rat heart
    • Popovich, B. K., K. R. Boheler, and W. H. Dillmann. 1989. Diabetes decreases creatine kinase enzyme activity and mRNA level in the rat heart. Am. J. Physiol. 257:E573-E577.
    • (1989) Am. J. Physiol , vol.257 , pp. E573-E577
    • Popovich, B.K.1    Boheler, K.R.2    Dillmann, W.H.3
  • 42
    • 0023772388 scopus 로고
    • Mitochondrial creatine phosphokinase deficiency in diabetic rat heart. Biochem. Biophys. Res
    • Savabi, F. 1988. Mitochondrial creatine phosphokinase deficiency in diabetic rat heart. Biochem. Biophys. Res. Commun. 154:469-475.
    • (1988) Commun , vol.154 , pp. 469-475
    • Savabi, F.1
  • 43
    • 0026321085 scopus 로고
    • Alteration of the phosphocreatine energy shuttle components in diabetic rat heart
    • Savabi, F., and A. Kirsch. 1991. Alteration of the phosphocreatine energy shuttle components in diabetic rat heart. J. Mol. Cell. Cardiol. 23:1323-1333.
    • (1991) J. Mol. Cell. Cardiol , vol.23 , pp. 1323-1333
    • Savabi, F.1    Kirsch, A.2
  • 45
    • 33748080109 scopus 로고    scopus 로고
    • Diabetes modulates differentially creatine kinase-specific activity responsiveness to estradiol-17beta and to raloxifene in rat organs
    • Somjen, D., M. Shen, N. Stern, and N. Mirsky. 2006. Diabetes modulates differentially creatine kinase-specific activity responsiveness to estradiol-17beta and to raloxifene in rat organs. J. Cell. Biochem. 99:133-139.
    • (2006) J. Cell. Biochem , vol.99 , pp. 133-139
    • Somjen, D.1    Shen, M.2    Stern, N.3    Mirsky, N.4
  • 46
    • 0033399059 scopus 로고    scopus 로고
    • Altered creatine kinase enzyme kinetics in diabetic cardiomyopathy. A(31)P NMR magnetization transfer study of the intact beating rat heart
    • Spindler, M., K. W. Saupe, R. Tian, S. Ahmed, M. A. Matlib, and J. S. Ingwall. 1999. Altered creatine kinase enzyme kinetics in diabetic cardiomyopathy. A(31)P NMR magnetization transfer study of the intact beating rat heart. J. Mol. Cell. Cardiol. 31:2175-2189.
    • (1999) J. Mol. Cell. Cardiol , vol.31 , pp. 2175-2189
    • Spindler, M.1    Saupe, K.W.2    Tian, R.3    Ahmed, S.4    Matlib, M.A.5    Ingwall, J.S.6
  • 47
    • 0029583159 scopus 로고
    • Glucose metabolism and left ventricular dysfunction are normalized by insulin and islet transplantation in mild diabetes in the rat
    • Stroedter, D., T. Schmidt, R. G. Bretzel, and K. Federlin. 1995. Glucose metabolism and left ventricular dysfunction are normalized by insulin and islet transplantation in mild diabetes in the rat. Acta Diabetol. 32:235-243.
    • (1995) Acta Diabetol , vol.32 , pp. 235-243
    • Stroedter, D.1    Schmidt, T.2    Bretzel, R.G.3    Federlin, K.4
  • 48
    • 0037046203 scopus 로고    scopus 로고
    • Adaptation and maladaptation of the heart in diabetes: Part I: General concepts
    • Taegtmeyer, H., P. McNulty, and M. E. Young. 2002. Adaptation and maladaptation of the heart in diabetes: part I: general concepts. Circulation 105:1727-1733.
    • (2002) Circulation , vol.105 , pp. 1727-1733
    • Taegtmeyer, H.1    McNulty, P.2    Young, M.E.3
  • 49
    • 0346308381 scopus 로고    scopus 로고
    • Improved method for accurate and efficient quantification of MRS data with use of prior knowledge
    • Vanhamme, L., A. van den Boogaart, and S. Van Huffel. 1997. Improved method for accurate and efficient quantification of MRS data with use of prior knowledge. J. Magn. Reson. 129:35-43.
    • (1997) J. Magn. Reson , vol.129 , pp. 35-43
    • Vanhamme, L.1    Van Den Boogaart, A.2    Van Huffel, S.3
  • 50
    • 0021349050 scopus 로고
    • Effects of moderate pressure overload cardiac hypertrophy on the distribution of creatine kinase isozymes
    • Vatner, D. E., and J. S. Ingwall. 1984. Effects of moderate pressure overload cardiac hypertrophy on the distribution of creatine kinase isozymes. Proc. Soc. Exp. Biol. Med. 175:5-9.
    • (1984) Proc. Soc. Exp. Biol. Med , vol.175 , pp. 5-9
    • Vatner, D.E.1    Ingwall, J.S.2
  • 51
    • 79952066868 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy: From the pathophysiology of the cardiac myocytes to current diagnosis and management strategies.
    • Voulgari, C., D. Papadogiannis, and N. Tentolouris. 2010. Diabetic cardiomyopathy: from the pathophysiology of the cardiac myocytes to current diagnosis and management strategies. Vasc. Health Risk Manag. 6:883-903.
    • (2010) Vasc. Health Risk Manag , vol.6 , pp. 883-903
    • Voulgari, C.1    Papadogiannis, D.2    Tentolouris, N.3
  • 52
    • 80052800016 scopus 로고    scopus 로고
    • The creatine kinase system and pleiotropic effects of creatine
    • Wallimann, T., M. Tokarska-Schlattner, and U. Schlattner. 2011. The creatine kinase system and pleiotropic effects of creatine. Amino Acids 40:1271-1296.
    • (2011) Amino Acids , vol.40 , pp. 1271-1296
    • Wallimann, T.1    Tokarska-Schlattner, M.2    Schlattner, U.3
  • 53
    • 0021924286 scopus 로고
    • Redistribution of creatine kinase isoenzymes in chronically overloaded myocardium.
    • Younes, A., J. M. Schneider, J. Bercovici, and B. Swynghedauw. 1985. Redistribution of creatine kinase isoenzymes in chronically overloaded myocardium. Cardiovasc. Res. 19:15-19.
    • (1985) Cardiovasc. Res , vol.19 , pp. 15-19
    • Younes, A.1    Schneider, J.M.2    Bercovici, J.3    Swynghedauw, B.4
  • 54
    • 0037117651 scopus 로고    scopus 로고
    • Adaptation and maladaptation of the heart in diabetes: Part II: Potential mechanisms
    • Young, M. E., P. McNulty, and H. Taegtmeyer. 2002. Adaptation and maladaptation of the heart in diabetes: part II: potential mechanisms. Circulation 105:1861-1870.
    • (2002) Circulation , vol.105 , pp. 1861-1870
    • Young, M.E.1    McNulty, P.2    Taegtmeyer, H.3


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