Long-term pre-treatment of antioxidant Ginkgo biloba extract EGb-761 attenuates cerebral-ischemia-induced neuronal damage in aged mice

Biomedicine and Pharmacotherapy

Volumn 85, Issue , 2017, Pages 256-263

  Zhou, Xiaomei ^a   Qi, Yinliang ^a   Chen, Ting ^a  

^a Dept of Respiratory and Critical Care Medicine   (China)

Author keywords

Aging; Antioxidant; Brain injury; EGb 761; Ginkgo biloba; Ischemia

Indexed keywords

ANTIOXIDANT; CYCLIC AMP DEPENDENT PROTEIN KINASE; GINKGO BILOBA EXTRACT; GLUTATHIONE; MALONALDEHYDE; NEUROPROTECTIVE AGENT; PHOSPHOPROTEIN PHOSPHATASE 2A; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SUPEROXIDE DISMUTASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOPROTEIN PHOSPHATASE 2; PLANT EXTRACT;

ADULT; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE SEVERITY; GENE EXPRESSION; LONG TERM CARE; MALE; MIDDLE AGED; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; TRAUMATIC BRAIN INJURY; UPREGULATION; AGE; ANIMAL; BRAIN; C57BL MOUSE; CONVALESCENCE; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; ENZYME ACTIVATION; INFARCTION, MIDDLE CEREBRAL ARTERY; METABOLISM; NERVE CELL; NERVE DEGENERATION; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; TIME FACTOR;

AGE FACTORS; AGING; ANIMALS; ANTIOXIDANTS; BRAIN; BRAIN EDEMA; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MICE, INBRED C57BL; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PLANT EXTRACTS; PROTEIN PHOSPHATASE 2; RECOVERY OF FUNCTION; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 85006820155     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2016.11.013     Document Type: Article

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