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Volumn 47, Issue 1, 2017, Pages 129-138

Comparison of anti-interleukin-5 therapies in patients with severe asthma: global and indirect meta-analyses of randomized placebo-controlled trials

Author keywords

[No Author keywords available]

Indexed keywords

BENRALIZUMAB; INTERLEUKIN 5; MEPOLIZUMAB; PLACEBO; RESLIZUMAB; ANTIASTHMATIC AGENT; BIOLOGICAL MARKER; MONOCLONAL ANTIBODY;

EID: 85006386654     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/cea.12853     Document Type: Review
Times cited : (96)

References (33)
  • 1
    • 84942787538 scopus 로고    scopus 로고
    • A summary of the new GINA strategy: a roadmap to asthma control
    • Reddel HK, Bateman ED, Becker A et al. A summary of the new GINA strategy: a roadmap to asthma control. Eur Respir J 2015; 46:622–39.
    • (2015) Eur Respir J , vol.46 , pp. 622-639
    • Reddel, H.K.1    Bateman, E.D.2    Becker, A.3
  • 2
    • 0037438409 scopus 로고    scopus 로고
    • Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway
    • Flood-Page PT, Menzies-Gow AN, Kay AB, Robinson DS. Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway. Am J Respir Crit Care Med 2003; 167:199–204.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 199-204
    • Flood-Page, P.T.1    Menzies-Gow, A.N.2    Kay, A.B.3    Robinson, D.S.4
  • 4
    • 0025037094 scopus 로고
    • Eosinophilic inflammation in asthma
    • Bousquet J, Chanez P, Lacoste JY et al. Eosinophilic inflammation in asthma. N Engl J Med 1990; 323:1033–9.
    • (1990) N Engl J Med , vol.323 , pp. 1033-1039
    • Bousquet, J.1    Chanez, P.2    Lacoste, J.Y.3
  • 5
    • 79551505136 scopus 로고    scopus 로고
    • Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome
    • Lötvall J, Akdis CA, Bacharier LB et al. Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome. J Allergy Clin Immunol 2011; 127:355–60.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 355-360
    • Lötvall, J.1    Akdis, C.A.2    Bacharier, L.B.3
  • 6
    • 84860679595 scopus 로고    scopus 로고
    • Asthma phenotypes: the evolution from clinical to molecular approaches
    • Wenzel SE. Asthma phenotypes: the evolution from clinical to molecular approaches. Nat Med 2012; 18:716–25.
    • (2012) Nat Med , vol.18 , pp. 716-725
    • Wenzel, S.E.1
  • 8
    • 84865558388 scopus 로고    scopus 로고
    • Immunologic therapeutic interventions in asthma: impact on natural history
    • Bourdin A, Humbert M, Chanez P. Immunologic therapeutic interventions in asthma: impact on natural history. Clin Chest Med 2012; 33:585–97.
    • (2012) Clin Chest Med , vol.33 , pp. 585-597
    • Bourdin, A.1    Humbert, M.2    Chanez, P.3
  • 9
    • 20044362008 scopus 로고    scopus 로고
    • Benefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATE
    • Humbert M, Beasley R, Ayres J et al. Benefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATE. Allergy 2005; 60:309–16.
    • (2005) Allergy , vol.60 , pp. 309-316
    • Humbert, M.1    Beasley, R.2    Ayres, J.3
  • 10
    • 84876883293 scopus 로고    scopus 로고
    • Exploring the effects of omalizumab in allergic asthma: an analysis of biomarkers in the EXTRA study
    • Hanania NA, Wenzel S, Rosén K et al. Exploring the effects of omalizumab in allergic asthma: an analysis of biomarkers in the EXTRA study. Am J Respir Crit Care Med 2013; 187:804–11.
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 804-811
    • Hanania, N.A.1    Wenzel, S.2    Rosén, K.3
  • 11
    • 69249150516 scopus 로고    scopus 로고
    • T-helper type 2-driven inflammation defines major subphenotypes of asthma
    • Woodruff PG, Modrek B, Choy DF et al. T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am J Respir Crit Care Med 2009; 180:388–95.
    • (2009) Am J Respir Crit Care Med , vol.180 , pp. 388-395
    • Woodruff, P.G.1    Modrek, B.2    Choy, D.F.3
  • 12
    • 81455155725 scopus 로고    scopus 로고
    • Reslizumab for poorly controlled, eosinophilic asthma: a randomized, placebo-controlled study
    • Castro M, Mathur S, Hargreave F et al. Reslizumab for poorly controlled, eosinophilic asthma: a randomized, placebo-controlled study. Am J Respir Crit Care Med 2011; 184:1125–32.
    • (2011) Am J Respir Crit Care Med , vol.184 , pp. 1125-1132
    • Castro, M.1    Mathur, S.2    Hargreave, F.3
  • 13
    • 84919382915 scopus 로고    scopus 로고
    • Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study
    • Castro M, Wenzel SE, Bleecker ER et al. Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study. Lancet Respir Med 2014; 2:879–90.
    • (2014) Lancet Respir Med , vol.2 , pp. 879-890
    • Castro, M.1    Wenzel, S.E.2    Bleecker, E.R.3
  • 14
    • 84887020563 scopus 로고    scopus 로고
    • Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia
    • Laviolette M, Gossage DL, Gauvreau G et al. Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia. J Allergy Clin Immunol 2013; 132:1086–1096.e5.
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 1086-1096.e5
    • Laviolette, M.1    Gossage, D.L.2    Gauvreau, G.3
  • 15
    • 84929026123 scopus 로고    scopus 로고
    • Reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: results from two multicentre, parallel, double-blind, randomised, placebo-controlled, phase 3 trials
    • Castro M, Zangrilli J, Wechsler ME et al. Reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: results from two multicentre, parallel, double-blind, randomised, placebo-controlled, phase 3 trials. Lancet Respir Med 2015; 3:355–66.
    • (2015) Lancet Respir Med , vol.3 , pp. 355-366
    • Castro, M.1    Zangrilli, J.2    Wechsler, M.E.3
  • 16
    • 84907423833 scopus 로고    scopus 로고
    • Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma
    • Bel EH, Wenzel SE, Thompson PJ et al. Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma. N Engl J Med 2014; 371:1189–97.
    • (2014) N Engl J Med , vol.371 , pp. 1189-1197
    • Bel, E.H.1    Wenzel, S.E.2    Thompson, P.J.3
  • 17
    • 84907424177 scopus 로고    scopus 로고
    • Mepolizumab treatment in patients with severe eosinophilic asthma
    • Ortega HG, Liu MC, Pavord ID et al. Mepolizumab treatment in patients with severe eosinophilic asthma. N Engl J Med 2014; 371:1198–207.
    • (2014) N Engl J Med , vol.371 , pp. 1198-1207
    • Ortega, H.G.1    Liu, M.C.2    Pavord, I.D.3
  • 18
    • 84865145614 scopus 로고    scopus 로고
    • Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial
    • Pavord ID, Korn S, Howarth P et al. Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet 2012; 380:651–9.
    • (2012) Lancet , vol.380 , pp. 651-659
    • Pavord, I.D.1    Korn, S.2    Howarth, P.3
  • 19
    • 36749065556 scopus 로고    scopus 로고
    • A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma
    • Flood-Page P, Swenson C, Faiferman I et al. A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma. Am J Respir Crit Care Med 2007; 176:1062–71.
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 1062-1071
    • Flood-Page, P.1    Swenson, C.2    Faiferman, I.3
  • 20
    • 61849086181 scopus 로고    scopus 로고
    • Mepolizumab and exacerbations of refractory eosinophilic asthma
    • Haldar P, Brightling CE, Hargadon B et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med 2009; 360:973–84.
    • (2009) N Engl J Med , vol.360 , pp. 973-984
    • Haldar, P.1    Brightling, C.E.2    Hargadon, B.3
  • 23
    • 79959925787 scopus 로고    scopus 로고
    • Interpreting indirect treatment comparisons and network meta-analysis for health-care decision making: report of the ISPOR task force on indirect treatment comparisons good research practices: Part 1
    • Jansen JP, Fleurence R, Devine B et al. Interpreting indirect treatment comparisons and network meta-analysis for health-care decision making: report of the ISPOR task force on indirect treatment comparisons good research practices: Part 1. Value Health 2011; 14:417–28.
    • (2011) Value Health , vol.14 , pp. 417-428
    • Jansen, J.P.1    Fleurence, R.2    Devine, B.3
  • 24
    • 70449411807 scopus 로고    scopus 로고
    • The BUGS project: evolution, critique and future directions
    • Lunn D, Spiegelhalter D, Thomas A, Best N. The BUGS project: evolution, critique and future directions. Stat Med 2009; 28:3049–67.
    • (2009) Stat Med , vol.28 , pp. 3049-3067
    • Lunn, D.1    Spiegelhalter, D.2    Thomas, A.3    Best, N.4
  • 26
    • 84875467652 scopus 로고    scopus 로고
    • Efficacy of anti-interleukin-5 therapy with mepolizumab in patients with asthma: a meta-analysis of randomized placebo-controlled trials
    • Liu Y, Zhang S, Li D, Jiang S. Efficacy of anti-interleukin-5 therapy with mepolizumab in patients with asthma: a meta-analysis of randomized placebo-controlled trials. PLoS ONE 2013; 8:e59872.
    • (2013) PLoS ONE , vol.8
    • Liu, Y.1    Zhang, S.2    Li, D.3    Jiang, S.4
  • 28
    • 84949108027 scopus 로고    scopus 로고
    • Mepolizumab: first global approval
    • Keating GM. Mepolizumab: first global approval. Drugs 2015; 75:2163–9.
    • (2015) Drugs , vol.75 , pp. 2163-2169
    • Keating, G.M.1
  • 29
    • 84903852024 scopus 로고    scopus 로고
    • The role of mepolizumab in atopic and nonatopic severe asthma with persistent eosinophilia
    • Ortega H, Chupp G, Bardin P et al. The role of mepolizumab in atopic and nonatopic severe asthma with persistent eosinophilia. Eur Respir J 2014; 44:239–41.
    • (2014) Eur Respir J , vol.44 , pp. 239-241
    • Ortega, H.1    Chupp, G.2    Bardin, P.3
  • 30
    • 80053084755 scopus 로고    scopus 로고
    • Lebrikizumab treatment in adults with asthma
    • Corren J, Lemanske RF, Hanania NA et al. Lebrikizumab treatment in adults with asthma. N Engl J Med 2011; 365:1088–98.
    • (2011) N Engl J Med , vol.365 , pp. 1088-1098
    • Corren, J.1    Lemanske, R.F.2    Hanania, N.A.3
  • 31
    • 84879401471 scopus 로고    scopus 로고
    • Dupilumab in persistent asthma with elevated eosinophil levels
    • Wenzel S, Ford L, Pearlman D et al. Dupilumab in persistent asthma with elevated eosinophil levels. N Engl J Med 2013; 368:2455–66.
    • (2013) N Engl J Med , vol.368 , pp. 2455-2466
    • Wenzel, S.1    Ford, L.2    Pearlman, D.3
  • 32
    • 84901759301 scopus 로고    scopus 로고
    • Effects of an anti-TSLP antibody on allergen-induced asthmatic responses
    • Gauvreau GM, O'Byrne PM, Boulet L-P et al. Effects of an anti-TSLP antibody on allergen-induced asthmatic responses. N Engl J Med 2014; 370:2102–10.
    • (2014) N Engl J Med , vol.370 , pp. 2102-2110
    • Gauvreau, G.M.1    O'Byrne, P.M.2    Boulet, L.-P.3
  • 33
    • 84929774279 scopus 로고    scopus 로고
    • Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme
    • Krug N, Hohlfeld JM, Kirsten A-M et al. Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme. N Engl J Med 2015; 372:1987–95.
    • (2015) N Engl J Med , vol.372 , pp. 1987-1995
    • Krug, N.1    Hohlfeld, J.M.2    Kirsten, A.-M.3


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