A novel anti-viral role for STAT3 in IFN-α signalling responses

Cellular and Molecular Life Sciences

Volumn 74, Issue 9, 2017, Pages 1755-1764

  Mahony, Rebecca ^a   Gargan, Siobhán ^a   Roberts, Kim L ^a   Bourke, Nollaig ^c   Keating, Sinead E ^a   Bowie, Andrew G ^a   O’Farrelly, Cliona ^a,b   Stevenson, Nigel J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Anti viral; IFN stimulated gene (ISG); Influenza virus; Interferon alpha (IFN ); Janus kinase signal transducer of activator of transcription (JAK STAT); STAT3; Vaccinia virus

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE; 2',5' OLIGOADENYLATE SYNTHETASE 2; ALPHA INTERFERON; INTERFERON REGULATORY FACTOR; INTERFERON STIMUSTIMULATED GENE FACTOR 15; MYXOVIRUS RESISTANCE GENE B PROTEIN; MYXOVIRUS RESISTANCE PROTEIN; PROTEIN KINASE R; STAT3 PROTEIN; UNCLASSIFIED DRUG; 2',5'-OLIGOADENYLATE SYNTHETASE 2, HUMAN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNE EVASION; INFLUENZA A VIRUS; LIMIT OF QUANTITATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; VACCINIA VIRUS; VIRUS INHIBITION; VIRUS REPLICATION; ANIMAL; CELL LINE; GENE SILENCING; METABOLISM; PHYSIOLOGY;

2',5'-OLIGOADENYLATE SYNTHETASE; ANIMALS; CELL LINE; EIF-2 KINASE; GENE KNOCKDOWN TECHNIQUES; HUMANS; INFLUENZA A VIRUS; INTERFERON-ALPHA; MICE; MYXOVIRUS RESISTANCE PROTEINS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; VACCINIA VIRUS;

EID: 85006373117     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-016-2435-3     Document Type: Article

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