Tumour homing and therapeutic effect of colloidal nanoparticles depend on the number of attached antibodies

Nature Communications

Volumn 7, Issue , 2016, Pages

  Colombo, Miriam ^a   Fiandra, Luisa ^b   Alessio, Giulia ^a,b   Mazzucchelli, Serena ^b   Nebuloni, Manuela ^b   De Palma, Clara ^b   Kantner, Karsten ^c   Pelaz, Beatriz ^c   Rotem, Rany ^a   Corsi, Fabio ^b,d   Parak, Wolfgang J ^c,e   Prosperi, Davide ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d IRCCS   (Italy)

^e CIC BIOMAGUNE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; GOLD NANOPARTICLE; NANOCONJUGATE; TRASTUZUMAB; TRASTUZUMAB GOLD NANOPARTICLE CONJUGATE; UNCLASSIFIED DRUG; ANTIBODY; DRUG CARRIER; MONOCLONAL ANTIBODY; NANOPARTICLE;

ANTIBODY; CANCER; COLLOID; EXPERIMENTAL STUDY; LIGAND; NANOPARTICLE; NUMERICAL MODEL; OPTIMIZATION; RODENT; TUMOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG TARGETING; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MCF 7 CELL LINE; MOLECULARLY TARGETED THERAPY; MOUSE; NONHUMAN; ANIMAL; CELL SURVIVAL; COLLOID; DRUG DELIVERY SYSTEM; EXPERIMENTAL NEOPLASM; IMMUNOLOGY; IMMUNOTHERAPY; PROCEDURES; TUMOR CELL LINE;

ANIMALS; ANTIBODIES; ANTIBODIES, MONOCLONAL; CELL LINE, TUMOR; CELL SURVIVAL; COLLOIDS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; IMMUNOTHERAPY; MICE; NANOPARTICLES; NEOPLASMS, EXPERIMENTAL;

EID: 85006372741     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms13818     Document Type: Article

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