Thyrotropin and Insulin-Like Growth Factor 1 Receptor Crosstalk Upregulates Sodium-Iodide Symporter Expression in Primary Cultures of Human Thyrocytes

Thyroid

Volumn 26, Issue 12, 2016, Pages 1794-1803

  Morgan, Sarah J ^a   Neumann, Susanne ^a   Marcus Samuels, Bernice ^a   Gershengorn, Marvin C ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

cAMP; IGF 1R; sodium iodide symporter; TSHR

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 8 [4 (1 AMINOCYCLOBUTYL)PHENYL] 9 PHENYL 1,2,4 TRIAZOLO[3,4 F][1,6]NAPHTHYRIDIN 3(2H) ONE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; DEIODINASE TYPE 2; LINSITINIB; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SODIUM IODIDE SYMPORTER; SOMATOMEDIN C RECEPTOR; THYROGLOBULIN; THYROID PEROXIDASE; THYROTROPIN; UNCLASSIFIED DRUG; COTRANSPORTER; PROTEIN KINASE B; SOMATOMEDIN C; THYROTROPIN RECEPTOR;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; PHARMACOLOGICAL BLOCKING; PRIMARY CELL CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; THYROID FOLLICULAR CELL; UPREGULATION; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION;

CELLS, CULTURED; HUMANS; INSULIN-LIKE GROWTH FACTOR I; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, IGF TYPE 1; RECEPTORS, THYROTROPIN; SIGNAL TRANSDUCTION; SYMPORTERS; THYROID EPITHELIAL CELLS; THYROTROPIN; UP-REGULATION;

EID: 85006314856     PISSN: 10507256     EISSN: 15579077     Source Type: Journal    
DOI: 10.1089/thy.2016.0323     Document Type: Article

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