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Volumn 10, Issue 6, 2016, Pages 623-628

Induction of heme oxygenase-1 with dietary quercetin reduces obesity-induced hepatic inflammation through macrophage phenotype switching

Author keywords

Inflammation; Macrophage; Obesity; Quercetin

Indexed keywords


EID: 85006314362     PISSN: 19761457     EISSN: 20056168     Source Type: Journal    
DOI: 10.4162/nrp.2016.10.6.623     Document Type: Article
Times cited : (37)

References (33)
  • 1
    • 33750999322 scopus 로고    scopus 로고
    • Role of Kupffer cells in host defense and liver disease
    • Bilzer M, Roggel F, Gerbes AL. Role of Kupffer cells in host defense and liver disease. Liver Int 2006;26:1175-86.
    • (2006) Liver Int , vol.26 , pp. 1175-1186
    • Bilzer, M.1    Roggel, F.2    Gerbes, A.L.3
  • 5
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 2007;117:175-84.
    • (2007) J Clin Invest , vol.117 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 9
    • 0033543566 scopus 로고    scopus 로고
    • Nrf2, a Cap’n’Collar transcription factor, regulates induction of the heme oxygenase-1 gene
    • Alam J, Stewart D, Touchard C, Boinapally S, Choi AM, Cook JL. Nrf2, a Cap’n’Collar transcription factor, regulates induction of the heme oxygenase-1 gene. J Biol Chem 1999;274:26071-8.
    • (1999) J Biol Chem , vol.274 , pp. 26071-26078
    • Alam, J.1    Stewart, D.2    Touchard, C.3    Boinapally, S.4    Choi, A.M.5    Cook, J.L.6
  • 10
    • 0036127426 scopus 로고    scopus 로고
    • Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
    • Lee TS, Chau LY. Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat Med 2002;8:240-6.
    • (2002) Nat Med , vol.8 , pp. 240-246
    • Lee, T.S.1    Chau, L.Y.2
  • 11
    • 77953527349 scopus 로고    scopus 로고
    • Role of heme oxygenase in inflammation, insulinsignalling, diabetes and obesity
    • Ndisang JF. Role of heme oxygenase in inflammation, insulinsignalling, diabetes and obesity. Mediators Inflamm 2010;2010: 359732.
    • (2010) Mediators Inflamm , vol.2010
    • Ndisang, J.F.1
  • 12
    • 44249095590 scopus 로고    scopus 로고
    • Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells
    • Kim DH, Burgess AP, Li M, Tsenovoy PL, Addabbo F, McClung JA, Puri N, Abraham NG. Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells. J Pharmacol Exp Ther 2008;325:833-40.
    • (2008) J Pharmacol Exp Ther , vol.325 , pp. 833-840
    • Kim, D.H.1    Burgess, A.P.2    Li, M.3    Tsenovoy, P.L.4    Addabbo, F.5    McClung, J.A.6    Puri, N.7    Abraham, N.G.8
  • 14
    • 0141988655 scopus 로고    scopus 로고
    • Anti-inflammatory actions of the heme oxygenase-1 pathway
    • Alcaraz MJ, Fernández P, Guillén MI. Anti-inflammatory actions of the heme oxygenase-1 pathway. Curr Pharm Des 2003;9:2541-51.
    • (2003) Curr Pharm Des , vol.9 , pp. 2541-2551
    • Alcaraz, M.J.1    Fernández, P.2    Guillén, M.I.3
  • 15
    • 84912124749 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 with hemin reduces obesity-induced adipose tissue inflammation via adipose macrophage phenotype switching
    • Tu TH, Joe Y, Choi HS, Chung HT, Yu R. Induction of heme oxygenase-1 with hemin reduces obesity-induced adipose tissue inflammation via adipose macrophage phenotype switching. Mediators Inflamm 2014;2014:290708.
    • (2014) Mediators Inflamm , pp. 2014
    • Tu, T.H.1    Joe, Y.2    Choi, H.S.3    Chung, H.T.4    Yu, R.5
  • 17
    • 84884884530 scopus 로고    scopus 로고
    • Therapeutic roles of heme oxygenase-1 in metabolic diseases: Curcumin and resveratrol analogues as possible inducers of heme oxygenase-1
    • Son Y, Lee JH, Chung HT, Pae HO. Therapeutic roles of heme oxygenase-1 in metabolic diseases: curcumin and resveratrol analogues as possible inducers of heme oxygenase-1. Oxid Med Cell Longev 2013;2013:639541.
    • (2013) Oxid Med Cell Longev , pp. 2013
    • Son, Y.1    Lee, J.H.2    Chung, H.T.3    Pae, H.O.4
  • 18
    • 1942473768 scopus 로고    scopus 로고
    • Quercetin, an anti-oxidant bioflavonoid, attenuates diabetic nephropathy in rats
    • Anjaneyulu M, Chopra K. Quercetin, an anti-oxidant bioflavonoid, attenuates diabetic nephropathy in rats. Clin Exp Pharmacol Physiol 2004;31:244-8.
    • (2004) Clin Exp Pharmacol Physiol , vol.31 , pp. 244-248
    • Anjaneyulu, M.1    Chopra, K.2
  • 19
    • 80052703398 scopus 로고    scopus 로고
    • Quercetin attenuates inflammation in human macrophages and adipocytes exposed to macrophage-conditioned media
    • Overman A, Chuang CC, McIntosh M. Quercetin attenuates inflammation in human macrophages and adipocytes exposed to macrophage-conditioned media. Int J Obes (Lond) 2011;35:1165-72.
    • (2011) Int J Obes (Lond) , vol.35 , pp. 1165-1172
    • Overman, A.1    Chuang, C.C.2    McIntosh, M.3
  • 20
    • 84863550183 scopus 로고    scopus 로고
    • Quercetin ameliorates cardiovascular, hepatic, and metabolic changes in diet-induced metabolic syndrome in rats
    • Panchal SK, Poudyal H, Brown L. Quercetin ameliorates cardiovascular, hepatic, and metabolic changes in diet-induced metabolic syndrome in rats. J Nutr 2012;142:1026-32.
    • (2012) J Nutr , vol.142 , pp. 1026-1032
    • Panchal, S.K.1    Poudyal, H.2    Brown, L.3
  • 21
    • 84900525909 scopus 로고    scopus 로고
    • Quercetin suppresses MIP-1alpha-induced adipose inflammation by downregulating its receptors CCR1/CCR5 and inhibiting inflammatory signaling
    • Noh HJ, Kim CS, Kang JH, Park JY, Choe SY, Hong SM, Yoo H, Park T, Yu R. Quercetin suppresses MIP-1alpha-induced adipose inflammation by downregulating its receptors CCR1/CCR5 and inhibiting inflammatory signaling. J Med Food 2014;17:550-7.
    • (2014) J Med Food , vol.17 , pp. 550-557
    • Noh, H.J.1    Kim, C.S.2    Kang, J.H.3    Park, J.Y.4    Choe, S.Y.5    Hong, S.M.6    Yoo, H.7    Park, T.8    Yu, R.9
  • 23
    • 84869869189 scopus 로고    scopus 로고
    • Dietary quercetin ameliorates nonalcoholic steatohepatitis induced by a high-fat diet in gerbils
    • Ying HZ, Liu YH, Yu B, Wang ZY, Zang JN, Yu CH. Dietary quercetin ameliorates nonalcoholic steatohepatitis induced by a high-fat diet in gerbils. Food Chem Toxicol 2013;52:53-60.
    • (2013) Food Chem Toxicol , vol.52 , pp. 53-60
    • Ying, H.Z.1    Liu, Y.H.2    Yu, B.3    Wang, Z.Y.4    Zang, J.N.5    Yu, C.H.6
  • 26
    • 85006285246 scopus 로고    scopus 로고
    • The inhibitory effect of quercetin on adipose tissue inflammation in mice fed on a high-fat diet
    • Kim CS, Yu R. The inhibitory effect of quercetin on adipose tissue inflammation in mice fed on a high-fat diet. Korean J Obes 2014;23: 170-8.
    • (2014) Korean J Obes , vol.23 , pp. 170-178
    • Kim, C.S.1    Yu, R.2
  • 27
    • 0141888287 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced nitric oxide production by flavonoids in RAW264.7 macrophages involves heme oxygenase-1
    • Lin HY, Juan SH, Shen SC, Hsu FL, Chen YC. Inhibition of lipopolysaccharide-induced nitric oxide production by flavonoids in RAW264.7 macrophages involves heme oxygenase-1. Biochem Pharmacol 2003;66:1821-32.
    • (2003) Biochem Pharmacol , vol.66 , pp. 1821-1832
    • Lin, H.Y.1    Juan, S.H.2    Shen, S.C.3    Hsu, F.L.4    Chen, Y.C.5
  • 28
    • 84881320210 scopus 로고    scopus 로고
    • Pathophysiology of NASH: Perspectives for a targeted treatment
    • Marra F, Lotersztajn S. Pathophysiology of NASH: perspectives for a targeted treatment. Curr Pharm Des 2013;19:5250-69.
    • (2013) Curr Pharm Des , vol.19 , pp. 5250-5269
    • Marra, F.1    Lotersztajn, S.2
  • 29
    • 84870042853 scopus 로고    scopus 로고
    • Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factoralpha production
    • Tosello-Trampont AC, Landes SG, Nguyen V, Novobrantseva TI, Hahn YS. Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factoralpha production. J Biol Chem 2012;287:40161-72.
    • (2012) J Biol Chem , vol.287 , pp. 40161-40172
    • Tosello-Trampont, A.C.1    Landes, S.G.2    Nguyen, V.3    Novobrantseva, T.I.4    Hahn, Y.S.5
  • 30
    • 84894815681 scopus 로고    scopus 로고
    • Quercetin reduces obesity-associated ATM infiltration and inflammation in mice: A mechanism including AMPKalpha1/SIRT 1
    • Dong J, Zhang X, Zhang L, Bian HX, Xu N, Bao B, Liu J. Quercetin reduces obesity-associated ATM infiltration and inflammation in mice: a mechanism including AMPKalpha1/SIRT 1. J Lipid Res 2014; 55:363-74.
    • (2014) J Lipid Res , vol.55 , pp. 363-374
    • Dong, J.1    Zhang, X.2    Zhang, L.3    Bian, H.X.4    Xu, N.5    Bao, B.6    Liu, J.7
  • 33
    • 84885930898 scopus 로고    scopus 로고
    • Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-kappaB-induced inflammatory mediators production in RAW 264.7 cells
    • Endale M, Park SC, Kim S, Kim SH, Yang Y, Cho JY, Rhee MH. Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-kappaB-induced inflammatory mediators production in RAW 264.7 cells. Immunobiology 2013;218: 1452-67.
    • (2013) Immunobiology , vol.218 , pp. 1452-1467
    • Endale, M.1    Park, S.C.2    Kim, S.3    Kim, S.H.4    Yang, Y.5    Cho, J.Y.6    Rhee, M.H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.