메뉴 건너뛰기




Volumn 60, Issue 7, 2012, Pages 1059-1063

Effect of insulin versus triple oral therapy on the progression of hepatic steatosis in type 2 diabetes

Author keywords

Hepatic steatosis; Insulin; NAFLD; Triglyceride; Type 2 diabetes

Indexed keywords

BIOLOGICAL MARKER; CHOLESTEROL; GLIBENCLAMIDE; GLUCOSE; HEMOGLOBIN A1C; INSULIN; INSULIN ASPART; LIPID; METFORMIN; PIOGLITAZONE; TRIACYLGLYCEROL;

EID: 85006136707     PISSN: 17088267     EISSN: 17088267     Source Type: Journal    
DOI: 10.2310/JIM.0b013e3182621c5f     Document Type: Article
Times cited : (10)

References (32)
  • 1
    • 10644220306 scopus 로고    scopus 로고
    • Prevalence of hepatic steatosis in an urban population in the united states: Impact of ethnicity
    • Browning JD, Szczepaniak LS, Dobbins R, et al. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology. 2004;40(6):1387-1395.
    • (2004) Hepatology. , vol.40 , Issue.6 , pp. 1387-1395
    • Browning, J.D.1    Szczepaniak, L.S.2    Dobbins, R.3
  • 2
    • 0141615879 scopus 로고    scopus 로고
    • Fatty liver in type 2 diabetes mellitus: Relation to regional adiposity, fatty acids, and insulin resistance
    • Kelley DE, McKolanis TM, Hegazi RA, et al. Fatty liver in type 2 diabetes mellitus: relation to regional adiposity, fatty acids, and insulin resistance. Am J Physiol Endocrinol Metab. 2003;285(4): E906YE916.
    • (2003) Am J Physiol Endocrinol Metab. , vol.285 , Issue.4
    • Kelley, D.E.1    McKolanis, T.M.2    Hegazi, R.A.3
  • 3
    • 0842313004 scopus 로고    scopus 로고
    • Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients
    • Bajaj M, Suraamornkul S, Piper P, et al. Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients. J Clin Endocrinol Metab. 2004;89(1):200-206.
    • (2004) J Clin Endocrinol Metab. , vol.89 , Issue.1 , pp. 200-206
    • Bajaj, M.1    Suraamornkul, S.2    Piper, P.3
  • 4
    • 0037567697 scopus 로고    scopus 로고
    • Pioglitazone reduces hepatic fat content and augments splanchnic glucose uptake in patients with type 2 diabetes
    • Bajaj M, Suraamornkul S, Pratipanawatr T, et al. Pioglitazone reduces hepatic fat content and augments splanchnic glucose uptake in patients with type 2 diabetes. Diabetes. 2003;52(6): 1364-1370.
    • (2003) Diabetes. , vol.52 , Issue.6 , pp. 1364-1370
    • Bajaj, M.1    Suraamornkul, S.2    Pratipanawatr, T.3
  • 5
    • 33751545838 scopus 로고    scopus 로고
    • A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis
    • 22
    • Belfort R, Harrison SA, Brown K, et al. A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. N Engl J Med. 30 2006;355(22):2297-2307.
    • (2006) N Engl J Med. , vol.30 , Issue.355 , pp. 2297-2307
    • Belfort, R.1    Harrison, S.A.2    Brown, K.3
  • 6
    • 1442355447 scopus 로고    scopus 로고
    • A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis
    • Promrat K, Lutchman G, Uwaifo GI, et al. A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis. Hepatology. 2004;39(1):188-196.
    • (2004) Hepatology. , vol.39 , Issue.1 , pp. 188-196
    • Promrat, K.1    Lutchman, G.2    Uwaifo, G.I.3
  • 7
    • 0012785395 scopus 로고    scopus 로고
    • Metformin reverses fatty liver disease in obese, leptin-deficient mice
    • Lin HZ, Yang SQ, Chuckaree C, et al. Metformin reverses fatty liver disease in obese, leptin-deficient mice. Nat Med. 2000;6(9): 998-1003.
    • (2000) Nat Med. , vol.6 , Issue.9 , pp. 998-1003
    • Lin, H.Z.1    Yang, S.Q.2    Chuckaree, C.3
  • 8
    • 0035883890 scopus 로고    scopus 로고
    • Metformin in non-alcoholic steatohepatitis
    • Marchesini G, Brizi M, Bianchi G, et al. Metformin in non-alcoholic steatohepatitis. Lancet. 2001;358(9285):893-894.
    • (2001) Lancet. , vol.358 , Issue.9285 , pp. 893-894
    • Marchesini, G.1    Brizi, M.2    Bianchi, G.3
  • 9
    • 19144365586 scopus 로고    scopus 로고
    • A randomized controlled trial of metformin versus vitamin e or prescriptive diet in nonalcoholic fatty liver disease
    • Bugianesi E, Gentilcore E, Manini R, et al. A randomized controlled trial of metformin versus vitamin E or prescriptive diet in nonalcoholic fatty liver disease. Am J Gastroenterol. 2005;100(5): 1082-1090.
    • (2005) Am J Gastroenterol. , vol.100 , Issue.5 , pp. 1082-1090
    • Bugianesi, E.1    Gentilcore, E.2    Manini, R.3
  • 10
    • 1642296465 scopus 로고    scopus 로고
    • Metformin in the treatment of patients with non-alcoholic steatohepatitis
    • Uygun A, Kadayifci A, Isik AT, et al. Metformin in the treatment of patients with non-alcoholic steatohepatitis. Aliment Pharmacol Ther. 2004;19(5):537-544.
    • (2004) Aliment Pharmacol Ther. , vol.19 , Issue.5 , pp. 537-544
    • Uygun, A.1    Kadayifci, A.2    Isik, A.T.3
  • 11
    • 3242745192 scopus 로고    scopus 로고
    • Effects of rosiglitazone and metformin on liver fat content, hepatic insulin resistance, insulin clearance, and gene expression in adipose tissue in patients with type 2 diabetes
    • Tiikkainen M, Hakkinen AM, Korsheninnikova E, et al. Effects of rosiglitazone and metformin on liver fat content, hepatic insulin resistance, insulin clearance, and gene expression in adipose tissue in patients with type 2 diabetes. Diabetes. 2004;53(8): 2169-2176.
    • (2004) Diabetes. , vol.53 , Issue.8 , pp. 2169-2176
    • Tiikkainen, M.1    Hakkinen, A.M.2    Korsheninnikova, E.3
  • 12
    • 3142670354 scopus 로고    scopus 로고
    • Metformin in the treatment of non-alcoholic steatohepatitis: A pilot open label trial
    • Nair S, Diehl AM, Wiseman M, et al. Metformin in the treatment of non-alcoholic steatohepatitis: a pilot open label trial. Aliment Pharmacol Ther. 2004;20(1):23-28.
    • (2004) Aliment Pharmacol Ther. , vol.20 , Issue.1 , pp. 23-28
    • Nair, S.1    Diehl, A.M.2    Wiseman, M.3
  • 13
    • 0036788388 scopus 로고    scopus 로고
    • Effects of insulin treatment in type 2 diabetic patients on intracellular lipid content in liver and skeletal muscle
    • Anderwald C, Bernroider E, Krssak M, et al. Effects of insulin treatment in type 2 diabetic patients on intracellular lipid content in liver and skeletal muscle. Diabetes. 2002;51(10):3025-3032.
    • (2002) Diabetes. , vol.51 , Issue.10 , pp. 3025-3032
    • Anderwald, C.1    Bernroider, E.2    Krssak, M.3
  • 14
    • 35048878739 scopus 로고    scopus 로고
    • Effect of pioglitazone therapy on myocardial and hepatic steatosis in insulin-treated patients with type 2 diabetes
    • Zib I, Jacob AN, Lingvay I, et al. Effect of pioglitazone therapy on myocardial and hepatic steatosis in insulin-treated patients with type 2 diabetes. J Investig Med. 2007;55(5):230-236.
    • (2007) J Investig Med. , vol.55 , Issue.5 , pp. 230-236
    • Zib, I.1    Jacob, A.N.2    Lingvay, I.3
  • 15
    • 34247593406 scopus 로고    scopus 로고
    • Effect of insulin-metformin combination on hepatic steatosis in patients with type 2 diabetes
    • Lingvay I, Raskin P, Szczepaniak LS. Effect of insulin-metformin combination on hepatic steatosis in patients with type 2 diabetes. J Diabetes Complications. 2007;21(3):137-142.
    • (2007) J Diabetes Complications. , vol.21 , Issue.3 , pp. 137-142
    • Lingvay, I.1    Raskin, P.2    Szczepaniak, L.S.3
  • 16
    • 0042655389 scopus 로고    scopus 로고
    • Benefits of combination therapy of insulin and oral hypoglycemic agents
    • Garber AJ. Benefits of combination therapy of insulin and oral hypoglycemic agents. Arch Intern Med. 2003;163(15): 1781-1782.
    • (2003) Arch Intern Med. , vol.163 , Issue.15 , pp. 1781-1782
    • Garber, A.J.1
  • 17
    • 70349675747 scopus 로고    scopus 로고
    • Insulin-based versus triple oral therapy for newly diagnosed type 2 diabetes: Which is better?
    • Lingvay I, Legendre JL, Kaloyanova PF, et al. Insulin-based versus triple oral therapy for newly diagnosed type 2 diabetes: which is better? Diabetes Care. 2009;32(10):1789-1795.
    • (2009) Diabetes Care. , vol.32 , Issue.10 , pp. 1789-1795
    • Lingvay, I.1    Legendre, J.L.2    Kaloyanova, P.F.3
  • 18
    • 0030946601 scopus 로고    scopus 로고
    • In vivo determination of intra-myocellular lipids in human muscle by means of localized 1h-mr-spectroscopy
    • Boesch C, Slotboom J, Hoppeler H, et al. In vivo determination of intra-myocellular lipids in human muscle by means of localized 1H-MR-spectroscopy. Magn Reson Med. 1997;37(4):484-493.
    • (1997) Magn Reson Med. , vol.37 , Issue.4 , pp. 484-493
    • Boesch, C.1    Slotboom, J.2    Hoppeler, H.3
  • 19
    • 0027457161 scopus 로고
    • Comparison of localized proton nmr signals of skeletal muscle and fat tissue in vivo: Two lipid compartments in muscle tissue
    • Schick F, Eismann B, Jung WI, et al. Comparison of localized proton NMR signals of skeletal muscle and fat tissue in vivo: two lipid compartments in muscle tissue. Magn Reson Med. 1993;29(2): 158-167.
    • (1993) Magn Reson Med. , vol.29 , Issue.2 , pp. 158-167
    • Schick, F.1    Eismann, B.2    Jung, W.I.3
  • 20
    • 0037371754 scopus 로고    scopus 로고
    • Myocardial triglycerides and systolic function in humans: In vivo evaluation by localized proton spectroscopy and cardiac imaging
    • Szczepaniak LS, Dobbins RL, Metzger GJ, et al. Myocardial triglycerides and systolic function in humans: in vivo evaluation by localized proton spectroscopy and cardiac imaging. Magn Reson Med. 2003;49(3):417-423.
    • (2003) Magn Reson Med. , vol.49 , Issue.3 , pp. 417-423
    • Szczepaniak, L.S.1    Dobbins, R.L.2    Metzger, G.J.3
  • 21
    • 0033007207 scopus 로고    scopus 로고
    • Measurement of intracellular triglyceride stores by h spectroscopy: Validation in vivo
    • Szczepaniak LS, Babcock EE, Schick F, et al. Measurement of intracellular triglyceride stores by H spectroscopy: validation in vivo. Am J Physiol. 1999;276(5 Pt 1):E977-989.
    • (1999) Am J Physiol. , vol.276 , Issue.5 PART 1
    • Szczepaniak, L.S.1    Babcock, E.E.2    Schick, F.3
  • 23
    • 34548385838 scopus 로고    scopus 로고
    • Cardiac steatosis in diabetes mellitus: A 1h-magnetic resonance spectroscopy study
    • McGavock JM, Lingvay I, Zib I, et al. Cardiac steatosis in diabetes mellitus: a 1H-magnetic resonance spectroscopy study. Circulation. 2007;116(10):1170-1175.
    • (2007) Circulation. , vol.116 , Issue.10 , pp. 1170-1175
    • McGavock, J.M.1    Lingvay, I.2    Zib, I.3
  • 24
    • 27144543513 scopus 로고    scopus 로고
    • Determination of triglyceride in the human myocardium by magnetic resonance spectroscopy: Reproducibility and sensitivity of the method
    • Reingold JS, McGavock JM, Kaka S, et al. Determination of triglyceride in the human myocardium by magnetic resonance spectroscopy: reproducibility and sensitivity of the method. Am J Physiol Endocrinol Metab. 2005;289(5):E935YE939.
    • (2005) Am J Physiol Endocrinol Metab. , vol.289 , Issue.5
    • Reingold, J.S.1    McGavock, J.M.2    Kaka, S.3
  • 26
    • 70349929485 scopus 로고    scopus 로고
    • Noninvasive quantification of pancreatic fat in humans
    • Lingvay I, Esser V, Legendre JL, et al. Noninvasive quantification of pancreatic fat in humans. J Clin Endocrinol Metab. 2009;94(10): 4070-4076.
    • (2009) J Clin Endocrinol Metab. , vol.94 , Issue.10 , pp. 4070-4076
    • Lingvay, I.1    Esser, V.2    Legendre, J.L.3
  • 27
    • 12144259379 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy to measure hepatic triglyceride content: Prevalence of hepatic steatosis in the general population
    • Szczepaniak LS, Nurenberg P, Leonard D, et al. Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population. Am J Physiol Endocrinol Metab. 2005;288(2):E462YE468.
    • (2005) Am J Physiol Endocrinol Metab. , vol.288 , Issue.2
    • Szczepaniak, L.S.1    Nurenberg, P.2    Leonard, D.3
  • 28
    • 0036184727 scopus 로고    scopus 로고
    • Bulk magnetic susceptibility effects on the assessment of intra- and extramyocellular lipids in vivo
    • Szczepaniak LS, Dobbins RL, Stein DT, et al. Bulk magnetic susceptibility effects on the assessment of intra- and extramyocellular lipids in vivo. Magn Reson Med. 2002;47(3):607-610.
    • (2002) Magn Reson Med. , vol.47 , Issue.3 , pp. 607-610
    • Szczepaniak, L.S.1    Dobbins, R.L.2    Stein, D.T.3
  • 29
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • Kleiner DE, Brunt EM, Van Natta M, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 2005;41(6):1313-1321.
    • (2005) Hepatology. , vol.41 , Issue.6 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van Natta, M.3
  • 30
    • 20444443042 scopus 로고    scopus 로고
    • Sampling variability of liver biopsy in nonalcoholic fatty liver disease
    • Ratziu V, Charlotte F, Heurtier A, et al. Sampling variability of liver biopsy in nonalcoholic fatty liver disease. Gastroenterology. 2005;128(7):1898-1906.
    • (2005) Gastroenterology. , vol.128 , Issue.7 , pp. 1898-1906
    • Ratziu, V.1    Charlotte, F.2    Heurtier, A.3
  • 31
    • 0031844760 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Assessment of variability in pathologic interpretations
    • Younossi ZM, Gramlich T, Liu YC, et al. Nonalcoholic fatty liver disease: assessment of variability in pathologic interpretations. Mod Pathol. 1998;11(6):560-565.
    • (1998) Mod Pathol. , vol.11 , Issue.6 , pp. 560-565
    • Younossi, Z.M.1    Gramlich, T.2    Liu, Y.C.3
  • 32
    • 33947131149 scopus 로고    scopus 로고
    • Effects of insulin therapy on liver fat content and hepatic insulin sensitivity in patients with type 2 diabetes
    • Juurinen L, Tiikkainen M, Hakkinen AM, et al. Effects of insulin therapy on liver fat content and hepatic insulin sensitivity in patients with type 2 diabetes. Am J Physiol Endocrinol Metab. 2007;292(3): E829YE835.
    • (2007) Am J Physiol Endocrinol Metab. , vol.292 , Issue.3
    • Juurinen, L.1    Tiikkainen, M.2    Hakkinen, A.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.