-
1
-
-
39749109478
-
Triggers, targets and treatments for thrombosis
-
Mackman N. Triggers, targets and treatments for thrombosis. Nature 2008;451:914–918.
-
(2008)
Nature
, vol.451
, pp. 914-918
-
-
Mackman, N.1
-
2
-
-
0036851876
-
Platelets in atherothrombosis
-
Ruggeri ZM. Platelets in atherothrombosis. Nat Med 2002;8:1227–1234.
-
(2002)
Nat Med
, vol.8
, pp. 1227-1234
-
-
Ruggeri, Z.M.1
-
3
-
-
84869854718
-
In vivo roles of factor XII
-
Renne T, Schmaier AH, Nickel KF, Blomback M, Maas C. In vivo roles of factor XII. Blood 2012;120:4296–4303.
-
(2012)
Blood
, vol.120
, pp. 4296-4303
-
-
Renne, T.1
Schmaier, A.H.2
Nickel, K.F.3
Blomback, M.4
Maas, C.5
-
4
-
-
72949092068
-
Activated human platelets induce factor XIIa-mediated contact activation
-
Back J, Sanchez J, Elgue G, Ekdahl KN, Nilsson B. Activated human platelets induce factor XIIa-mediated contact activation. Biochem Biophys Res Commun 2010;391:11–17.
-
(2010)
Biochem Biophys Res Commun
, vol.391
, pp. 11-17
-
-
Back, J.1
Sanchez, J.2
Elgue, G.3
Ekdahl, K.N.4
Nilsson, B.5
-
5
-
-
32344441350
-
Platelets promote coagulation factor XII-mediated proteolytic cascade systems in plasma
-
Johne J, Blume C, Benz P, Pozgajová M, Ullrich M, Schuh K, Nieswandt B, Walter U, Renné T. Platelets promote coagulation factor XII-mediated proteolytic cascade systems in plasma. Biol Chem 2006;387:173–178.
-
(2006)
Biol Chem
, vol.387
, pp. 173-178
-
-
Johne, J.1
Blume, C.2
Benz, P.3
Pozgajová, M.4
Ullrich, M.5
Schuh, K.6
Nieswandt, B.7
Walter, U.8
Renné, T.9
-
6
-
-
0019370191
-
Contributions of human platelets to the proteolytic activation of blood coagulation factors XII and XI
-
Walsh PN, Griffin JH. Contributions of human platelets to the proteolytic activation of blood coagulation factors XII and XI. Blood 1981;57:106–118.
-
(1981)
Blood
, vol.57
, pp. 106-118
-
-
Walsh, P.N.1
Griffin, J.H.2
-
7
-
-
0013853269
-
Availability of platelet Factor 3 and activation of factor XII in thrombasthenia
-
Castaldi PA, Larrieu MJ, Caen J. Availability of platelet Factor 3 and activation of factor XII in thrombasthenia. Nature 1965;207:422–424.
-
(1965)
Nature
, vol.207
, pp. 422-424
-
-
Castaldi, P.A.1
Larrieu, M.J.2
Caen, J.3
-
8
-
-
78650015566
-
Decreased in vitro thrombin generation and clot stability in human FXII-null blood and plasma
-
Pluthero FG, Ryan C, Williams S, Brandao LR, Kahr WH. Decreased in vitro thrombin generation and clot stability in human FXII-null blood and plasma. Br J Haematol 2011;152:111–112.
-
(2011)
Br J Haematol
, vol.152
, pp. 111-112
-
-
Pluthero, F.G.1
Ryan, C.2
Williams, S.3
Brandao, L.R.4
Kahr, W.H.5
-
9
-
-
84964756537
-
New agents for thromboprotection. A role for factor XII and XIIa inhibition
-
Labberton L, Kenne E, Renne T. New agents for thromboprotection. A role for factor XII and XIIa inhibition. Hamostaseologie 2015;35:338–350.
-
(2015)
Hamostaseologie
, vol.35
, pp. 338-350
-
-
Labberton, L.1
Kenne, E.2
Renne, T.3
-
10
-
-
71149116751
-
Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo
-
Müller F, Mutch NJ, Schenk WA, Smith SA, Esterl L, Spronk HM, Schmidbauer S, Gahl WA, Morrissey JH, Renné T. Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo. Cell 2009;139:1143–1156.
-
(2009)
Cell
, vol.139
, pp. 1143-1156
-
-
Müller, F.1
Mutch, N.J.2
Schenk, W.A.3
Smith, S.A.4
Esterl, L.5
Spronk, H.M.6
Schmidbauer, S.7
Gahl, W.A.8
Morrissey, J.H.9
Renné, T.10
-
11
-
-
84893834884
-
A factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk
-
222ra217
-
Larsson M, Rayzman V, Nolte MW, Nickel KF, Björkqvist J, Jämsä A, Hardy MP, Fries M, Schmidbauer S, Hedenqvist P, Broomé M, Pragst I, Dickneite G, Wilson MJ, Nash AD, Panousis C, Renné T. A factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk. Sci Transl Med 2014;6:222ra217
-
(2014)
Sci Transl Med
, vol.6
-
-
Larsson, M.1
Rayzman, V.2
Nolte, M.W.3
Nickel, K.F.4
Björkqvist, J.5
Jämsä, A.6
Hardy, M.P.7
Fries, M.8
Schmidbauer, S.9
Hedenqvist, P.10
Broomé, M.11
Pragst, I.12
Dickneite, G.13
Wilson, M.J.14
Nash, A.D.15
Panousis, C.16
Renné, T.17
-
12
-
-
67650759738
-
Inorganic polyphosphate: Essential for growth and survival
-
Rao NN, Gomez-Garcia MR, Kornberg A. Inorganic polyphosphate: Essential for growth and survival. Annu Rev Biochem 2009;78:605–647.
-
(2009)
Annu Rev Biochem
, vol.78
, pp. 605-647
-
-
Rao, N.N.1
Gomez-Garcia, M.R.2
Kornberg, A.3
-
13
-
-
7244225025
-
Human platelet dense granules contain polyphosphate and are similar to acidocalcisomes of bacteria and unicellular eukaryotes
-
Ruiz FA, Lea CR, Oldfield E, Docampo R. Human platelet dense granules contain polyphosphate and are similar to acidocalcisomes of bacteria and unicellular eukaryotes. J Biol Chem 2004;279:44250–44257.
-
(2004)
J Biol Chem
, vol.279
, pp. 44250-44257
-
-
Ruiz, F.A.1
Lea, C.R.2
Oldfield, E.3
Docampo, R.4
-
14
-
-
78149439563
-
Polyphosphate exerts differential effects on blood clotting, depending on polymer size
-
Smith SA, Choi SH, Davis-Harrison R, Huyck J, Boettcher J, Rienstra CM, Morrissey JH. Polyphosphate exerts differential effects on blood clotting, depending on polymer size. Blood 2010;116:4353–4359.
-
(2010)
Blood
, vol.116
, pp. 4353-4359
-
-
Smith, S.A.1
Choi, S.H.2
Davis-Harrison, R.3
Huyck, J.4
Boettcher, J.5
Rienstra, C.M.6
Morrissey, J.H.7
-
15
-
-
84939227812
-
Defective glycosylation of coagulation factor XII underlies hereditary angioedema type III
-
Björkqvist J, de Maat S, Lewandrowski U, Di Gennaro A, Oschatz C, Schönig K, Nöthen MM, Drouet C, Braley H, Nolte MW, Sickmann A, Panousis C, Maas C, Renné T. Defective glycosylation of coagulation factor XII underlies hereditary angioedema type III. J Clin Invest 2015;125:3132–3146.
-
(2015)
J Clin Invest
, vol.125
, pp. 3132-3146
-
-
Björkqvist, J.1
de Maat, S.2
Lewandrowski, U.3
Di Gennaro, A.4
Oschatz, C.5
Schönig, K.6
Nöthen, M.M.7
Drouet, C.8
Braley, H.9
Nolte, M.W.10
Sickmann, A.11
Panousis, C.12
Maas, C.13
Renné, T.14
-
16
-
-
84926205053
-
Plasma contact system activation drives anaphylaxis in severe mast cell-mediated allergic reactions
-
Sala-Cunill A, Björkqvist J, Senter R, Guilarte M, Cardona V, Labrador M, Nickel KF, Butler L, Luengo O, Kumar P, Labberton L, Long A, Di Gennaro A, Kenne E, Jämsä A, Krieger T, Schlüter H, Fuchs T, Flohr S, Hassiepen U, Cumin F, McCrae K, Maas C, Stavrou E, Renné T. Plasma contact system activation drives anaphylaxis in severe mast cell-mediated allergic reactions. J Allergy Clin Immunol 2015;135:1031–1043.
-
(2015)
J Allergy Clin Immunol
, vol.135
, pp. 1031-1043
-
-
Sala-Cunill, A.1
Björkqvist, J.2
Senter, R.3
Guilarte, M.4
Cardona, V.5
Labrador, M.6
Nickel, K.F.7
Butler, L.8
Luengo, O.9
Kumar, P.10
Labberton, L.11
Long, A.12
Di Gennaro, A.13
Kenne, E.14
Jämsä, A.15
Krieger, T.16
Schlüter, H.17
Fuchs, T.18
Flohr, S.19
Hassiepen, U.20
Cumin, F.21
McCrae, K.22
Maas, C.23
Stavrou, E.24
Renné, T.25
more..
-
17
-
-
84897026647
-
Polyphosphate suppresses complement via the terminal pathway
-
Wat JM, Foley JH, Krisinger MJ, Ocariza LM, Lei V, Wasney GA, Lameignere E, Strynadka NC, Smith SA, Morrissey JH, Conway EM. Polyphosphate suppresses complement via the terminal pathway. Blood 2014;123:768–776.
-
(2014)
Blood
, vol.123
, pp. 768-776
-
-
Wat, J.M.1
Foley, J.H.2
Krisinger, M.J.3
Ocariza, L.M.4
Lei, V.5
Wasney, G.A.6
Lameignere, E.7
Strynadka, N.C.8
Smith, S.A.9
Morrissey, J.H.10
Conway, E.M.11
-
18
-
-
84892897673
-
Time-dependent degradation and tissue factor addition mask the ability of platelet polyphosphates in activating factor XII-mediated coagulation
-
Nickel KF, Spronk HM, Mutch NJ, Renne T. Time-dependent degradation and tissue factor addition mask the ability of platelet polyphosphates in activating factor XII-mediated coagulation. Blood 2013;122:3847–3849.
-
(2013)
Blood
, vol.122
, pp. 3847-3849
-
-
Nickel, K.F.1
Spronk, H.M.2
Mutch, N.J.3
Renne, T.4
-
19
-
-
84986557913
-
Neutralizing blood-borne polyphosphate in-vivo provides safe thromboprotection
-
Labberton L, Kenne E, Long AT, Nickel KF, Di Gennaro A, Rigg RA, Hernandez JS, Butler L, Maas C, Stavrou EX, Renné T. Neutralizing blood-borne polyphosphate in-vivo provides safe thromboprotection. Nat Commun 2016;7:12616. doi: 10.1038/ncomms12616.
-
(2016)
Nat Commun
, vol.7
, pp. 12616
-
-
Labberton, L.1
Kenne, E.2
Long, A.T.3
Nickel, K.F.4
Di Gennaro, A.5
Rigg, R.A.6
Hernandez, J.S.7
Butler, L.8
Maas, C.9
Stavrou, E.X.10
Renné, T.11
-
21
-
-
0027439691
-
An exopolyphosphatase of Escherichia coli the enzyme and its ppx gene in a polyphosphate operon
-
Akiyama M, Crooke E, Kornberg A. An exopolyphosphatase of Escherichia coli the enzyme and its ppx gene in a polyphosphate operon. J Biol Chem 1993;268:633–639.
-
(1993)
J Biol Chem
, vol.268
, pp. 633-639
-
-
Akiyama, M.1
Crooke, E.2
Kornberg, A.3
-
22
-
-
84929319009
-
Platelet secretion: From haemostasis to wound healing and beyond
-
Golebiewska EM, Poole AW. Platelet secretion: From haemostasis to wound healing and beyond. Blood Rev 2015;29:153–162.
-
(2015)
Blood Rev
, vol.29
, pp. 153-162
-
-
Golebiewska, E.M.1
Poole, A.W.2
-
24
-
-
1642535447
-
Differential role of protein kinase C delta isoform in agonist-induced dense granule secretion in human platelets
-
Murugappan S, Tuluc F, Dorsam RT, Shankar H, Kunapuli SP. Differential role of protein kinase C delta isoform in agonist-induced dense granule secretion in human platelets. J Biol Chem 2004;279:2360–2367.
-
(2004)
J Biol Chem
, vol.279
, pp. 2360-2367
-
-
Murugappan, S.1
Tuluc, F.2
Dorsam, R.T.3
Shankar, H.4
Kunapuli, S.P.5
-
25
-
-
84862729665
-
Polyphosphate: An ancient molecule that links platelets, coagulation, and inflammation
-
Morrissey JH, Choi SH, Smith SA. Polyphosphate: An ancient molecule that links platelets, coagulation, and inflammation. Blood 2012;119:5972–5979.
-
(2012)
Blood
, vol.119
, pp. 5972-5979
-
-
Morrissey, J.H.1
Choi, S.H.2
Smith, S.A.3
-
26
-
-
32244448581
-
Polyphosphate modulates blood coagulation and fibrinolysis
-
Smith SA, Mutch NJ, Baskar D, Rohloff P, Docampo R, Morrissey JH. Polyphosphate modulates blood coagulation and fibrinolysis. Proc Natl Acad Sci USA 2006;103:903–908.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 903-908
-
-
Smith, S.A.1
Mutch, N.J.2
Baskar, D.3
Rohloff, P.4
Docampo, R.5
Morrissey, J.H.6
-
27
-
-
84255201932
-
Polyphosphate is a cofactor for the activation of factor XI by thrombin
-
Choi SH, Smith SA, Morrissey JH. Polyphosphate is a cofactor for the activation of factor XI by thrombin. Blood 2011;118:6963–6970.
-
(2011)
Blood
, vol.118
, pp. 6963-6970
-
-
Choi, S.H.1
Smith, S.A.2
Morrissey, J.H.3
-
28
-
-
84925310761
-
Polyphosphate accelerates factor V activation by factor XIa
-
Choi SH, Smith SA, Morrissey JH. Polyphosphate accelerates factor V activation by factor XIa. Thromb Haemost 2014;113:599–604.
-
(2014)
Thromb Haemost
, vol.113
, pp. 599-604
-
-
Choi, S.H.1
Smith, S.A.2
Morrissey, J.H.3
-
29
-
-
50349100313
-
Polyphosphate enhances fibrin clot structure
-
Smith SA, Morrissey JH. Polyphosphate enhances fibrin clot structure. Blood 2008;112:2810–2816.
-
(2008)
Blood
, vol.112
, pp. 2810-2816
-
-
Smith, S.A.1
Morrissey, J.H.2
-
30
-
-
77952974521
-
Polyphosphate modifies the fibrin network and down-regulates fibrinolysis by attenuating binding of tPA and plasminogen to fibrin
-
Mutch NJ, Engel R, Uitte de Willige S, Philippou H, Ariens RA. Polyphosphate modifies the fibrin network and down-regulates fibrinolysis by attenuating binding of tPA and plasminogen to fibrin. Blood 2010;115:3980–3988.
-
(2010)
Blood
, vol.115
, pp. 3980-3988
-
-
Mutch, N.J.1
Engel, R.2
Uitte de Willige, S.3
Philippou, H.4
Ariens, R.A.5
-
31
-
-
84910090892
-
Size-controlled synthesis of granular polyphosphate nanoparticles at physiologic salt concentrations for blood clotting
-
Donovan AJ, Kalkowski J, Smith SA, Morrissey JH, Liu Y. Size-controlled synthesis of granular polyphosphate nanoparticles at physiologic salt concentrations for blood clotting. Biomacromolecules 2014;15:3976–3984.
-
(2014)
Biomacromolecules
, vol.15
, pp. 3976-3984
-
-
Donovan, A.J.1
Kalkowski, J.2
Smith, S.A.3
Morrissey, J.H.4
Liu, Y.5
-
32
-
-
84955171842
-
Factor XII: A novel target for safe prevention of thrombosis and inflammation
-
Kenne E, Nickel KF, Long AT, Fuchs TA, Stavrou EX, Stahl FR, Renné T. Factor XII: A novel target for safe prevention of thrombosis and inflammation. J Intern Med 2015;278:571–585.
-
(2015)
J Intern Med
, vol.278
, pp. 571-585
-
-
Kenne, E.1
Nickel, K.F.2
Long, A.T.3
Fuchs, T.A.4
Stavrou, E.X.5
Stahl, F.R.6
Renné, T.7
|