Time-dependent degradation and tissue factor addition mask the ability of platelet polyphosphates in activating factor XII–mediated coagulation

Blood

Volumn 122, Issue 23, 2013, Pages 3847-3849

  Nickel, Katrin Faye ^a   Spronk, Henri M ^b   Mutch, Nicola J ^c   Renné, Thomas ^a,d  

^a KAROLINSKA INSTITUTE   (Sweden)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF ABERDEEN   (United Kingdom)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; BLOOD CLOTTING FACTOR 12; CALCIMYCIN; CALCIUM; PHOSPHOLIPID; PLATELET POLYPHOSPHATE; POLYPHOSPHATE; PROCOAGULANT; THROMBIN; THROMBIN RECEPTOR ACTIVATING PEPTIDE 6; THROMBOPLASTIN; UNCLASSIFIED DRUG;

BLOOD CLOTTING; BLOOD CLOTTING TIME; COMPARATIVE STUDY; HUMAN; LETTER; PRIORITY JOURNAL; PROTEIN DEGRADATION; THROMBOCYTE ACTIVATION; THROMBOCYTE FREE PLASMA; THROMBOCYTE FUNCTION; ANIMAL; BLOOD; METABOLISM; THROMBOCYTE;

ANIMALS; BLOOD PLATELETS; FACTOR XII; HUMANS; POLYPHOSPHATES;

EID: 84892897673     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-09-525840     Document Type: Letter

References (13)

1. Caen J, Wu Q. Hageman factor, platelets and polyphosphates: early history and recent connection. J Thromb Haemost. 2010;8(8):1670-1674.
2. Smith SA, Mutch NJ, Baskar D, Rohloff P, Docampo R, Morrissey JH. Polyphosphate modulates blood coagulation and fibrinolysis. Proc Natl Acad Sci U S A. 2006;103(4):903-908.
3. Müller F, Mutch NJ, Schenk WA, et al. Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo. Cell. 2009;139(6):1143-1156.
4. Semeraro F, Ammollo CT, Morrissey JH, et al. Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4. Blood. 2011;118(7):1952-1961.
5. Ghosh S, Shukla D, Suman K, et al. Inositol hexakisphosphate kinase 1 maintains hemostasis in mice by regulating platelet polyphosphate levels. Blood. 2013;122(8):1478-1486.
6. Smith SA, Choi SH, Davis-Harrison R, et al. Polyphosphate exerts differential effects on blood clotting, depending on polymer size. Blood. 2010;116(20):4353-4359.
7. Smith SA, Choi SH, Collins JN, Travers RJ, Cooley BC, Morrissey JH. Inhibition of polyphosphate as a novel strategy for preventing thrombosis and inflammation. Blood. 2012;120(26):5103-5110.
8. Faxälv L, Boknäs N, Ström JO, et al. Putting polyphosphates to the test: evidence against platelet-induced activation of factor XII [published online ahead of print July 29, 2013]. Blood. 2013;122(23):3818-3824.
9. Smith SA, Morrissey JH. Comment on Putting polyphosphates to the test: evidence against platelet-induced activation of factor XII. e-Letter online, August 26, 2013. http://bloodjournal.hematologylibrary.org/content/early/2013/07/29/blood-2013-05-499384/reply.
10. Butenas S, Mann KG. Active tissue factor in blood? Nat Med. 2004;10(11):1155-1156; author reply 1156.
11. Ramström S, Rånby M, Lindahl TL. Platelet phosphatidylserine exposure and procoagulant activity in clotting whole blood - different effects of collagen, TRAP and calcium ionophore A23187. Thromb Haemost. 2003;89(1):132-141.
12. Onder S, Kazmanli K, Kok FN. Alteration of PTFE surface to increase its blood compatibility. J Biomater Sci Polym Ed. 2011;22(11):1443-1457.
13. Takahashi K, Aoki T, Kohmoto S, et al. Activation of kallikrein-kinin system in human plasma with purified serine protease from Dermatophagoides farinae. Int Arch Allergy Appl Immunol. 1990;91(1):80-85.