Impaired recognition of mycobacterium tuberculosis by alveolar macrophages from diabetic mice

Journal of Infectious Diseases

Volumn 214, Issue 11, 2016, Pages 1629-1637

  Martinez, Nuria ^a   Ketheesan, Natkunam ^b   West, Kim ^a   Vallerskog, Therese ^a   Kornfeld, Hardy ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b JAMES COOK UNIVERSITY   (Australia)

Author keywords

Alveolar macrophages; CD14; Diabetes; MARCO; Mycobacterium tuberculosis; Phagocytosis

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; CD14 ANTIGEN; CORD FACTOR; LEUKOCYTE ANTIGEN; MACROPHAGE RECEPTOR WITH COLLAGENOUS STRUCTURE; UNCLASSIFIED DRUG; IMMUNOGLOBULIN RECEPTOR; MARCO PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; BACTERIAL CELL WALL; BONE MARROW DERIVED MACROPHAGE; CONFERENCE PAPER; CONTROLLED STUDY; DIABETES MELLITUS; EX VIVO STUDY; IN VIVO STUDY; INFECTION SENSITIVITY; LUNG ALVEOLUS MACROPHAGE; MALE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; ANIMAL; C57BL MOUSE; CHEMISTRY; DISEASE PREDISPOSITION; GENE EXPRESSION; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MICROBIOLOGY;

ANIMALS; ANTIGENS, CD14; DIABETES MELLITUS; DISEASE SUSCEPTIBILITY; GENE EXPRESSION; LYMPHOCYTE ACTIVATION; MACROPHAGES, ALVEOLAR; MALE; MICE, INBRED C57BL; MYCOBACTERIUM TUBERCULOSIS; PHAGOCYTOSIS; RECEPTORS, IMMUNOLOGIC;

EID: 85006109659     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiw436     Document Type: Conference Paper

References (31)

1. Martinez N, Kornfeld H. Diabetes and immunity to tuberculosis. Eur J Immunol 2014; 44:617-26.
2. Restrepo BI, Schlesinger LS. Impact of diabetes on the natural history of tuberculosis. Diabetes Res Clin Pract 2014; 106:191-9.
3. Odone A, Houben RM, White RG, Lonnroth K. The effect of diabetes and under-nutrition trends on reaching 2035 global tuberculosis targets. Lancet Diabetes En-docrinol 2014; 2:754-64.
4. Martens GW, Arikan MC, Lee J, Ren F, Greiner D, Kornfeld H. Tuberculosis sus-ceptibility of diabetic mice. Am J Respir Cell Mol Biol 2007; 37:518-24.
5. Vallerskog T, Martens GW, Kornfeld H. Diabetic mice display a delayed adaptive immune response to Mycobacterium tuberculosis. J Immunol 2010; 184:6275-82.
6. Wolf AJ, Desvignes L, Linas B, et al. Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs. J Exp Med 2008; 205:105-15.
7. Wolf AJ, Linas B, Trevejo-Nunez GJ, et al. Mycobacterium tuberculosis infects den-dritic cells with high frequency and impairs their function in vivo. J Immunol 2007; 179:2509-19.
8. Humphreys IR, Stewart GR, Turner DJ, et al. A role for dendritic cells in the dissemination of mycobacterial infection. Microbes Infect 2006; 8:1339-46.
9. Bhatt K, Hickman SP, Salgame P. Cutting edge: a new approach to modeling early lung immunity in murine tuberculosis. J Immunol 2004; 172:2748-51.
10. Blomgran R, Ernst JD. Lung neutrophils facilitate activation of naive antigen-specific CD4+ T cells during Mycobacterium tuberculosis infection. J Immunol 2011; 186:7110-9.
11. Khader SA, Partida-Sanchez S, Bell G, et al. Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection. J Exp Med 2006; 203:1805-15.
12. Bowdish DM, Sakamoto K, Kim MJ, et al. MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis. PLoS Pathog 2009; 5:e1000474.
13. Manigrasso MB, Juranek J, Ramasamy R, Schmidt AM. Unlocking the biology of RAGE in diabetic microvascular complications. Trends Endocrinol Metab 2014; 25:15-22.
14. Ishikawa E, Ishikawa T, Morita YS, et al. Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle. J Exp Med 2009; 206:2879-88.
15. Repasy T, Lee J, Marino S, et al. Intracellular bacillary burden reflects a burst size for Mycobacterium tuberculosis in vivo. PLoS Pathog 2013; 9:e1003190.
16. Repasy T, Martinez N, Lee J, West K, Li W, Kornfeld H. Bacillary replication and macrophage necrosis are determinants of neutrophil recruitment in tuberculosis. Microbes Infect 2015; 17:564-74.
17. Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001; 414:813-20.
18. Divangahi M, Desjardins D, Nunes-Alves C, Remold HG, Behar SM. Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis. Nat Immunol 2010; 11:751-8.
19. Jeon CY, Murray MB. Diabetes mellitus increases the risk of active tuberculosis: a systematic review of 13 observational studies. PLoS Med 2008; 5:e152.
20. Hossain MM, Norazmi MN. Pattern recognition receptors and cytokines in My-cobacterium tuberculosis infection-the double-edged sword? Biomed Res Int 2013; 2013:179174.
21. Pecora ND, Gehring AJ, Canaday DH, Boom WH, Harding CV. Mycobacterium tuberculosis LprA is a lipoprotein agonist of TLR2 that regulates innate immunity and APC function. J Immunol 2006; 177:422-9.
22. Quesniaux VJ, Nicolle DM, Torres D, et al. Toll-like receptor 2 (TLR2)-depen-dent-positive and TLR2-independent-negative regulation of proinflammatory cy-tokines by mycobacterial lipomannans. J Immunol 2004; 172:4425-34.
23. Murphy J, Summer R, Wilson AA, Kotton DN, Fine A. The prolonged life-span of alveolar macrophages. Am J Respir Cell Mol Biol 2008; 38:380-5.
24. Epelman S, Lavine KJ, Randolph GJ. Origin and functions of tissue macrophages. Immunity 2014; 41:21-35.
25. Gautier EL, Shay T, Miller J, et al. Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue mac-rophages. Nat Immunol 2012; 13:1118-28.
26. Chackerian AA, Alt JM, Perera TV, Dascher CC, Behar SM. Dissemination of My-cobacterium tuberculosis is influenced by host factors and precedes the initiation of T-cell immunity. Infect Immun 2002; 70:4501-9.
27. Tian T, Woodworth J, Skold M, Behar SM. In vivo depletion of CD11c+ cells delays the CD4+ T cell response to Mycobacterium tuberculosis and exacerbates the outcome of infection. J Immunol 2005; 175:3268-72.
28. Giacco F, Brownlee M. Oxidative stress and diabetic complications. Circ Res 2010; 107:1058-70.
29. Viswanathan V, Kumpatla S, Aravindalochanan V, et al. Prevalence of diabetes and pre-diabetes and associated risk factors among tuberculosis patients in India. PLoS One 2012; 7:e41367.
30. Gupta S, Shenoy VP, Bairy I, Srinivasa H, Mukhopadhyay C. Diabetes mellitus and HIV as co-morbidities in tuberculosis patients of rural south India. J Infect Public Health 2011; 4:140-4.
31. Litwinoff E, Hurtado Del Pozo C, Ramasamy R, Schmidt AM. Emerging targets for therapeutic development in diabetes and its complications: the RAGE Signaling Pathway. Clin Pharmacol Ther 2015; 98:135-44.