Specific Frontostriatal Circuits for Impaired Cognitive Flexibility and Goal-Directed Planning in Obsessive-Compulsive Disorder: Evidence From Resting-State Functional Connectivity

Biological Psychiatry

Volumn 81, Issue 8, 2017, Pages 708-717

  Vaghi, Matilde M ^a   Vértes, Petra E ^a   Kitzbichler, Manfred G ^a   Apergis Schoute, Annemieke M ^a   van der Flier, Febe E ^a   Fineberg, Naomi A ^b,c   Sule, Akeem ^d   Zaman, Rashid ^a   Voon, Valerie ^a   Kundu, Prantik ^e   Bullmore, Edward T ^a   Robbins, Trevor W ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b HERTFORDSHIRE PARTNERSHIP UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^c UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

^d Lillyhall Business Centre   (United Kingdom)

^e MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Cognitive flexibility; Frontostriatal circuits; Functional connectivity; Goal directed planning; Obsessive compulsive disorder; Resting state

Indexed keywords

ADULT; ARTICLE; BOLD SIGNAL; BRAIN REGION; CLINICAL ARTICLE; COGNITION; COGNITIVE FLEXIBILITY; CONNECTOME; CONTROLLED STUDY; EMOTION; FEMALE; FRONTOSTRIATAL CIRCUIT; FUNCTIONAL CONNECTIVITY; GOAL DIRECTED PLANNING; HUMAN; MALE; MENTAL PERFORMANCE; MOTIVATION; NUCLEUS ACCUMBENS; OBSESSIVE COMPULSIVE DISORDER; PRIORITY JOURNAL; RESTING STATE NETWORK; SYMPTOM; VENTROLATERAL PREFRONTAL CORTEX; ATTENTION; BRAIN MAPPING; CORPUS STRIATUM; EXECUTIVE FUNCTION; NERVE TRACT; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PHYSIOLOGY; PREFRONTAL CORTEX; SEVERITY OF ILLNESS INDEX;

ADULT; ATTENTION; BRAIN MAPPING; COGNITION; CORPUS STRIATUM; EXECUTIVE FUNCTION; FEMALE; GOALS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEURAL PATHWAYS; OBSESSIVE-COMPULSIVE DISORDER; PREFRONTAL CORTEX; SEVERITY OF ILLNESS INDEX;

EID: 85005963590     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2016.08.009     Document Type: Article

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