Antidepressant compounds can be both pro- and anti-inflammatory in human hippocampal cells

International Journal of Neuropsychopharmacology

Volumn 18, Issue 3, 2015, Pages

  Horowitz, Mark Abie ^a   Wertz, Jasmin ^a   Zhu, Danhui ^a   Cattaneo, Annamaria ^a,c   Musaelyan, Ksenia ^a   Nikkheslat, Naghmeh ^a   Thuret, Sandrine ^b   Pariante, Carmine Maria ^a   Zunszain, Patricia Ana ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b James Black Centre   (United Kingdom)

^c IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

Author keywords

Cytokines; Depression; Inflammation; Neural stem cells; Omega 3 fatty acids

Indexed keywords

AGOMELATINE; ALPHA INTERFERON; DOCOSAHEXAENOIC ACID; GAMMA INTERFERON INDUCIBLE PROTEIN 10; ICOSAPENTAENOIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 15; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MOCLOBEMIDE; SERTRALINE; VENLAFAXINE; ANTIDEPRESSANT AGENT; ANTIINFLAMMATORY AGENT; CYTOKINE; MESSENGER RNA; OMEGA 3 FATTY ACID;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; HIPPOCAMPUS; HUMAN; HUMAN CELL; IMMUNOMODULATION; NEURAL STEM CELL; PRIORITY JOURNAL; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; SIGNAL TRANSDUCTION; STEM CELL; TIME FACTOR;

ANTI-INFLAMMATORY AGENTS; ANTIDEPRESSIVE AGENTS; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FATTY ACIDS, OMEGA-3; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HUMANS; INTERLEUKIN-1BETA; NF-KAPPA B; RNA, MESSENGER; SIGNAL TRANSDUCTION; STEM CELLS; TIME FACTORS;

EID: 85005865066     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1093/ijnp/pyu076     Document Type: Article

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