Moclobemide exerts anti-inflammatory effect in lipopolysaccharide-activated primary mixed glial cell culture

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 382, Issue 5-6, 2010, Pages 409-417

  Bielecka, A M ^a   Paul Samojedny, M ^a   Obuchowicz, E ^a  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

IL 1 ; IL 10; Moclobemide; NF B p65 subunit; Primary mixed glia culture; TNF

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; MOCLOBEMIDE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL CULTURE; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CYTOKINE PRODUCTION; DEGENERATIVE DISEASE; GENE EXPRESSION; GLIA CELL; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NEUROTRANSMISSION; NONHUMAN; PROTEIN EXPRESSION; RAT; SEROTONIN UPTAKE;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIDEPRESSIVE AGENTS; CELL NUCLEUS; CELLS, CULTURED; INTERLEUKIN-10; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MOCLOBEMIDE; MONOAMINE OXIDASE INHIBITORS; NEUROGLIA; RATS; RATS, WISTAR; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 78649959103     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-010-0535-4     Document Type: Article

References (39)

1. H Allain A Lieury F Brunet-Bourgin C Mirabaud P Trebon F Le Coz JM Gandon 1992 Antidepressants and cognition: comparative effects of moclobemide, viloxazine and maprotiline Psychopharmacology 106 56 61 10.1007/BF02246237
2. A Boland J Gérardy D Mossay D Delapierre V Seutin 2002 Pirlindole and dehydropirlindole protect rat cultured neuronal cells against oxidative stress-induced cell death through a mechanism unrelated to MAO-A inhibition Br J Pharmacol 135 730 10.1038/sj.bjp.0704519
3. U Bonnet T Leniger M Wiemann 2000 Moclobemide reduces intracellular pH and neuronal activity of CA3 neurones in guinea-pig hippocampal slices-implication for its neuroprotective properties Neuropharmocology 23 2067 2074 10.1016/S0028-3908(00)00033-2 (Pubitemid 30645630)
4. MM Bradford 1976 A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 248 254 1:CAS:528:DyaE28XksVehtrY%3D 10.1016/0003-2697(76)90527- 3 942051
5. SH Chiou HH Ku TH Tsai HL Lin LH Chen CS Chien LL Ho CH Lee YL Chang 2006 Moclobemide upregulated Bcl-2 expression and induced neural stem cell differentiation into serotoninergic neuron via extracellular-regulated kinase pathway Br J Pharmacol 148 587 598 1:CAS:528:DC%2BD28XmsVansrc%3D 10.1038/sj.bjp.0706766 16702990 (Pubitemid 43993050)
6. M Da Prada R Kettler HH Keller WP Burkard D Muggli-Maniglio WE Haefely 1989 Neurochemical profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type A J Pharmacol Exp Ther 248 400 414 2783611 (Pubitemid 19063520)
7. N Drigues T Poltyrev C Bejar M Weinstock MBH Youdim 2003 cDNA gene expression profile of rat hippocampus after chronic treatment with antidepressant drugs J Neuronal Transm. 110 1413 1436 1:CAS:528: DC%2BD3sXps1yitL8%3D 10.1007/s00702-003-0077-8 (Pubitemid 38041347)
8. LW Fitzgerald L Kaplinsky HK Kimelberg 1990 Serotonin metabolism by monoamine oxidase in rat primary astrocyte cultures J Neurochem 55 2008 2014 1:CAS:528:DyaK3MXjs1Cgtw%3D%3D 10.1111/j.1471-4159.1990.tb05789.x 1700071
9. I Glezer AI Simard S Rivest 2007 Neuroprotective role of innate immune system by microglia Neuroscience 29 867 883 10.1016/j.neuroscience.2007.02.055 (Pubitemid 47102534)
10. I Goshen R Yirmiya 2009 Interleukin-1 (IL-1): a central regulator of stress responses Front Neuroendocrinol 30 30 45 1:CAS:528:DC%2BD1MXhsVKnug%3D%3D 10.1016/j.yfrne.2008.10.001 19017533
11. J Haddad 2009 Thymulin and zinc (Zn2+)-mediated inhibition of endotoxin-induced production of proinflammatory cytokines and NF-kappaB nuclear translocation and activation in the alveolar epithelium: unraveling the molecular immunomodulatory, anti-inflammatory effect of thymulin/Zn2+ in vitro Mol Immunol 47 205 214 1:CAS:528:DC%2BD1MXhsVyjurvJ 10.1016/j.molimm.2009.09.034 19850345
12. NP Hailer C Vogt HW Korf F Dehghani 2005 Interleukin-1beta exacerbates and interleukin-1 receptor antagonist attenuates neuronal injury and microglial activation after excitotoxic damage in organotypic hippocampal slice cultures Eur J Neurosci 21 2347 2360 10.1111/j.1460-9568.2005.04067.x 15932594 (Pubitemid 40813918)
13. S Hashioka YH Han S Fuji T Kato A Monji H Utsumi M Sawada H Nakanishi S Kanba 2007 Phosphatidylserine and phosphatidylcholine-containing liposomes inhibit amyloid beta and interferon-gamma-induced microglial activation Free Radic Biol Med 1 945 954 10.1016/j.freeradbiomed.2006.12.003 (Pubitemid 46356888)
14. YY Huang CH Peng YP Yang CC Wu WM Hsu HJ Wang KH Chan YP Chou SJ Chen YL Chang 2008 Desipramine activated Bcl-2 expression and inhibited lipopolysaccharide-induced apoptosis in hippocampus-derived adult neural stem cells J Pharmacol Sci 104 61 72 10.1254/jphs.FP0061255
15. J Hwang LT Zhen J Ock MG Lee SH Kim HW Lee HC Park K Suk 2009 Inhibition of glial inflammatory activation and neurotoxicity by tricyclic antidepressants Neuropharmacology 55 826 834 10.1016/j.neuropharm.2008.06.045
16. G Kenis M Maes 2002 Effect of antidepressants on the production of cytokines Int J Neuropsychopharmacol 54 401 412 10.1017/S1461145702003164 (Pubitemid 35470359)
17. C Konradi P Riederer K Jellinger R Denney 1987 Cellular action of MAO inhibitors J Neural Transm Suppl 25 15 25 1:STN:280:DyaL1c7hslCkug%3D%3D 3480938
18. JW Koo RS Duman 2009 Evidence for IL-1 receptor blockade as a therapeutic strategy for the treatment of depression Curr Opin Investig Drugs 10 664 671 1:CAS:528:DC%2BC3cXnt1Khs7o%3D 19579172
19. A Lin C Song G Kenis E Bosmans R De Jongh S Scharpe M Maes 2000 The in vitro immunosuppressive effects of moclobemide in healthy volunteers J Affect Disord 58 69 74 1:STN:280:DC%2BD3c3isFyitg%3D%3D 10.1016/S0165-0327(99)00076-2 10760560 (Pubitemid 30173213)
20. M Maes 1999 Major depression and activation of the inflammatory response system Adv Exp Med Biol 461 25 46 1:CAS:528:DC%2BD3cXis1equ7c%3D 10.1007/978-0-585-37970-8-2 10442165
21. M Maes R Yirmyia J Noraberg S Brene J Hibbeln G Perini M Kubera P Bob B Lerer M Maj 2009 The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression Metab Brain Dis 24 27 53 1:CAS:528:DC%2BD1MXhvVOjsro%3D 10.1007/s11011-008- 9118-1 19085093
22. CA Massaad BP Portier Taglialatela 2004 Inhibition of transcription factor activity by nuclear compartment-associated Bcl-2 J Biol Chem 24 54470 54478 10.1074/jbc.M407659200 (Pubitemid 40053187)
23. B Mesples F Plaisant P Gressens 2003 Effects of interleukin-10 on neonatal excitotoxic brain lesions in mice Brain Res Dev Brain Res 14 25 32 10.1016/S0165-3806(02)00636-3 (Pubitemid 36315689)
24. S Mori R Zanardi M Popoli S Garbini N Brunello E Smeraldi G Racagni J Perez 1998 cAMP-dependent phosphorylation system after short and long-term administration of moclobemide J Psychiatr Res 32 111 115 1:STN:280: DyaK1czlvV2hsQ%3D%3D 10.1016/S0022-3956(98)00003-X 9694007 (Pubitemid 28306461)
25. BT Mosman L Jean JM Landesman 1983 Studies using lectins to determine mineral interactions with cellular membranes Environ Health Perspect 51 23 25 10.2307/3429723
26. E Obuchowicz J Kowalski K Labuzek R Krysiak J Pendzich ZS Herman 2006 Amitriptyline and nortriptyline inhibit interleukin-1 release by rat mixed glial and microglial cell cultures Int J Neuropsychopharmacol 9 27 35 1:CAS:528:DC%2BD28Xht1eitg%3D%3D 10.1017/S146114570500547X 15963243 (Pubitemid 43068332)
27. E Pinteaux NJ Rothwell H Boutin 2006 Neuroprotective actions of endogenous interleukin-1 receptor antagonist (IL-1ra) are mediated by glia Glia 1 551 556 10.1002/glia.20308
28. L Qian ML Block SJ Wei CF Lin J Reece H Pang B Wilson JS Hong PM Flood 2006 Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase J Pharmacol Exp Ther 3 44 52 10.1124/jpet.106.106351 (Pubitemid 44455109)
29. CR Raetz C Whitfield 2002 Lipopolysaccharide endotoxins Annu Rev Biochem 71 635 700 1:CAS:528:DC%2BD38Xos1Clt7w%3D 10.1146/annurev.biochem.71.110601. 135414 12045108 (Pubitemid 34800232)
30. P Riederer L Lachenmayer G Laux 2004 Clinical applications of MAO-inhibitors Curr Med Chem 1 2033 2043
31. M Sawada A Suzumura H Hosoya T Marunouchi T Nagatsu 1999 Interleukin-10 inhibits both production of cytokines and expression of cytokine receptors in microglia J Neurochem 72 1466 1472 1:CAS:528:DyaK1MXitFCks7k%3D 10.1046/j.1471-4159.1999.721466.x 10098850 (Pubitemid 29140817)
32. OJ Schiepers MC Wichers M Maes 2005 Cytokines and major depression Prog Neuropsychopharmacol Biol Psychiatry 29 201 217 1:CAS:528:DC%2BD2MXptlCqsQ%3D%3D 10.1016/j.pnpbp.2004.11.003 15694227 (Pubitemid 40202906)
33. RS Smith 1991 The macrophage theory of depression Med Hypotheses 4 298 306 10.1016/0306-9877(91)90272-Z
34. H Takeuchi S Jin J Wang G Zhang J Kawanokuchi R Kuno Y Sonobe T Mizuno A Suzumura 2006 Tumor necrosis factor-alpha induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner J Biol Chem 28 21362 21368 10.1074/jbc.M600504200 (Pubitemid 44115475)
35. Tichauer J, Sand K, von Bernhardi R (2007) Modulation by astrocytes of microglial cell mediated neuroinflammation: effect on the activation of microglia signaling pathway. Neuroimmunomodulation 14:165-174
36. GE Trott HJ Friese M Menzel G Nissen 1992 Use of moclobemide in children with attention deficit hyperactivity disorder Psychopharmacology 106 134 136 10.1007/BF02246258
37. M Verleye R Steinschneider F Xavier FX Bernard JM Jean-Marie Gillardin 2007 Moclobemide attenuates anoxia and glutamate-induced neuronal damage in vitro independently of interaction with glutamate receptor subtypes Brain Res 23 8 30
38. Vollmar P, Haghikia A, Dermietzel R, Faustmann PM (2008) Venlafaxine exhibits an anti-inflammatory effect in an inflammatory co-culture model. Int J Neuropsychopharmacol 11-7
39. M Zhu F Gu J Shi J Hu Y Hu Z Zhao 2008 Increased oxidative stress and astrogliosis responses in conditional double-knockout mice of Alzheimer-like presenilin-1 and presenilin-2 Free Radic Biol Med 15 1493 1499 10.1016/j.freeradbiomed.2008.08.027