Poststroke Depression: A Scientific Statement for Healthcare Professionals from the American Heart Association/American Stroke Association

Stroke

Volumn 48, Issue 2, 2017, Pages e30-e43

  Towfighi, Amytis ^a   Ovbiagele, Bruce ^a   El Husseini, Nada ^a   Hackett, Maree L ^a   Jorge, Ricardo E ^a   Kissela, Brett M ^a   Mitchell, Pamela H ^a   Skolarus, Lesli E ^a   Whooley, Mary A ^a   Williams, Linda S ^a  

^a NONE

Author keywords

AHA Scientific Statements; depression; management; prevention control; screening; stroke; treatment

Indexed keywords

ANTIDEPRESSANT AGENT;

CAREGIVER; CEREBROVASCULAR ACCIDENT; CLINICAL OUTCOME; CLINICAL PRACTICE; DEPRESSION; DISEASE ASSOCIATION; FUNCTIONAL ASSESSMENT; HEALTH CARE UTILIZATION; HUMAN; INCIDENCE; MEDICAL HISTORY; META ANALYSIS (TOPIC); MORTALITY; MULTICENTER STUDY (TOPIC); NEUROMODULATION; PATHOPHYSIOLOGY; POSTSTROKE DEPRESION; PREVALENCE; PREVENTIVE MEDICINE; PRIORITY JOURNAL; PSYCHOPHARMACOTHERAPY; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SCREENING; SELF CARE; STROKE REHABILITATION; SYSTEMATIC REVIEW (TOPIC); COMPLICATION; EPIDEMIOLOGY; HEALTH CARE PERSONNEL; MEDICAL SOCIETY; STANDARDS; STROKE; UNITED STATES;

AMERICAN HEART ASSOCIATION; DEPRESSION; HEALTH PERSONNEL; HUMANS; STROKE; UNITED STATES;

EID: 85004066465     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STR.0000000000000113     Document Type: Review

References (102)

1. Hackett ML, Pickles K. Part I: frequency of depression after stroke: an updated systematic review and meta-analysis of observational studies. Int J Stroke. 2014;9:1017-1025. doi: 10.1111/ijs.12357.
2. Kutlubaev MA, Hackett ML. Part II: predictors of depression after stroke and impact of depression on stroke outcome: an updated systematic review of observational studies. Int J Stroke. 2014;9:1026-1036. doi: 10.1111/ijs.12356.
3. Bartoli F, Lillia N, Lax A, Crocamo C, Mantero V, Carrà G, Agostoni E, Clerici M. Depression after stroke and risk of mortality: a systematic review and meta-analysis. Stroke Res Treat. 2013;2013:862978. doi: 10.1155/2013/862978.
4. Hasin DS, Goodwin RD, Stinson FS, Grant BF. Epidemiology of major depressive disorder: results from the National Epidemiologic Survey on Alcoholism and Related Conditions. Arch Gen Psychiatry. 2005;62:1097-1106. doi: 10.1001/archpsyc.62.10.1097.
5. Kessler RC, Chiu WT, Demler O, Merikangas KR, Walters EE. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005;62:617-627. doi: 10.1001/archpsyc.62.6.617.
6. Ayerbe L, Ayis S, Crichton S, Wolfe CD, Rudd AG. The natural history of depression up to 15 years after stroke: the South London Stroke Register. Stroke. 2013;44:1105-1110. doi: 10.1161/STROKEAHA. 111.679340.
7. Hackett ML, Yapa C, Parag V, Anderson CS. Frequency of depression after stroke: a systematic review of observational studies. Stroke. 2005;36:1330-1340. doi: 10.1161/01.STR.0000165928.19135.35.
8. Ayerbe L, Ayis S, Wolfe CD, Rudd AG. Natural history, predictors and outcomes of depression after stroke: systematic review and meta-analy-sis. Br J Psychiatry. 2013;202:14-21. doi: 10.1192/bjp.bp.111.107664.
9. Ng KC, Chan KL, Straughan PT. A study of post-stroke depression in a rehabilitative center. Acta Psychiatr Scand. 1995;92:75-79.
10. Nys GM, van Zandvoort MJ, van der Worp HB, de Haan EH, de Kort PL, Kappelle LJ. Early depressive symptoms after stroke: neuropsychologi-cal correlates and lesion characteristics. J Neurol Sci. 2005;228:27-33. doi: 10.1016/j.jns.2004.09.031.
11. Murphy E. Social origins of depression in old age. Br J Psychiatry. 1982;141:135-142.
12. Whyte EM, Mulsant BH. Post stroke depression: epidemiology, patho-physiology, and biological treatment. Biol Psychiatry. 2002;52:253-264.
13. Folstein MF, Maiberger R, McHugh PR. Mood disorder as a specifc complication of stroke. J Neurol Neurosurg Psychiatry. 1977;40: 1018-1020.
14. Burvill P, Johnson G, Jamrozik K, Anderson C, Stewart-Wynne E. Risk factors for post-stroke depression. Int J Geriatr Psychiatry. 1997;12:219-226.
15. Lieberman D, Friger M, Fried V, Grinshpun Y, Mytlis N, Tylis R, Galinsky D, Lieberman D. Characterization of elderly patients in rehabilitation: stroke versus hip fracture. Disabil Rehabil. 1999;21:542-547.
16. Starkstein SE, Fedoroff JP, Price TR, Leiguarda R, Robinson RG. Anosognosia in patients with cerebrovascular lesions. A study of causative factors. Stroke. 1992;23:1446-1453.
17. Fujikawa T, Yamawaki S, Touhouda Y. Incidence of silent cerebral infarction in patients with major depression. Stroke. 1993;24:1631-1634.
18. Alexopoulos GS, Meyers BS, Young RC, Kakuma T, Silbersweig D, Charlson M. Clinically defned vascular depression. Am J Psychiatry. 1997;154:562-565. doi: 10.1176/ajp.154.4.562.
19. Loubinoux I, Kronenberg G, Endres M, Schumann-Bard P, Freret T, Filipkowski RK, Kaczmarek L, Popa-Wagner A. Post-stroke depression: mechanisms, translation and therapy. J Cell Mol Med. 2012;16:1961-1969. doi: 10.1111/j.1582-4934.2012.01555.x.
20. Craft TK, DeVries AC. Role of IL-1 in poststroke depressive-like behavior in mice. Biol Psychiatry. 2006;60:812-818. doi: 10.1016/j. biopsych.2006.03.011.
21. Snaphaan L, van der Werf S, Kanselaar K, de Leeuw FE. Post-stroke depressive symptoms are associated with post-stroke characteristics. Cerebrovasc Dis. 2009;28:551-557. doi: 10.1159/000247598.
22. Altieri M, Maestrini I, Mercurio A, Troisi P, Sgarlata E, Rea V, Di Piero V, Lenzi GL. Depression after minor stroke: prevalence and predictors. Eur J Neurol. 2012;19:517-521. doi: 10.1111/j.1468-1331. 2011.03583.x.
23. Robinson RG, Shoemaker WJ, Schlumpf M, Valk T, Bloom FE. Effect of experimental cerebral infarction in rat brain on catecholamines and behaviour. Nature. 1975;255:332-334.
24. Robinson RG, Kubos KL, Starr LB, Rao K, Price TR. Mood changes in stroke patients: relationship to lesion location. Compr Psychiatry. 1983;24:555-566.
25. Carson AJ, MacHale S, Allen K, Lawrie SM, Dennis M, House A, Sharpe M. Depression after stroke and lesion location: a systematic review. Lancet. 2000;356:122-126. doi: 10.1016/S0140-6736(00)02448-X.
26. Wei N, Yong W, Li X, Zhou Y, Deng M, Zhu H, Jin H. Post-stroke depression and lesion location: a systematic review. J Neurol. 2015;262:81-90. doi: 10.1007/s00415-014-7534-1.
27. Yu L, Liu CK, Chen JW, Wang SY, Wu YH, Yu SH. Relationship between post-stroke depression and lesion location: a meta-analysis. Kaohsiung J Med Sci. 2004;20:372-380. doi: 10.1016/ S1607-551X(09)70173-1.
28. Kim JM, Stewart R, Kang HJ, Kim SW, Shin IS, Kim HR, Shin MG, Kim JT, Park MS, Cho KH, Yoon JS. A longitudinal study of SLC6A4 DNA promoter methylation and poststroke depression. J Psychiatr Res. 2013;47:1222-1227. doi: 10.1016/j.jpsychires.2013.04.010.
29. Kim JM, Stewart R, Kang HJ, Kim SY, Kim SW, Shin IS, Park MS, Kim HR, Shin MG, Cho KH, Yoon JS. A longitudinal study of BDNF promoter methylation and genotype with poststroke depression. J Affect Disord. 2013;149:93-99. doi: 10.1016/j.jad.2013.01.008.
30. Kim JM, Stewart R, Kim SW, Shin IS, Kim JT, Park MS, Park SW, Kim YH, Cho KH, Yoon JS. Associations of cytokine gene polymorphisms with post-stroke depression. World J Biol Psychiatry. 2012;13:579-587. doi: 10.3109/15622975.2011.588247.
31. Spalletta G, Bossù P, Ciaramella A, Bria P, Caltagirone C, Robinson RG. The etiology of poststroke depression: a review of the literature and a new hypothesis involving infammatory cytokines. Mol Psychiatry. 2006;11:984-991. doi: 10.1038/sj.mp.4001879.
32. Rocco A, Afra J, Toscano M, Sirimarco G, Di Clemente L, Altieri M, Lenzi GL, Di Piero V. Acute subcortical stroke and early serotonergic modification: a IDAP study. Eur J Neurol. 2007;14:1378-1382. doi: 10.1111/j.1468-1331.2007.01985.x.
33. Newberg AR, Davydow DS, Lee HB. Cerebrovascular disease basis of depression: post-stroke depression and vascular depression. Int Rev Psychiatry. 2006;18:433-441. doi: 10.1080/09540260600935447.
34. Noonan K, Carey LM, Crewther SG. Meta-analyses indicate associations between neuroendocrine activation, deactivation in neu-rotrophic and neuroimaging markers in depression after stroke. J Stroke Cerebrovasc Dis. 2013;22:e124-e135. doi: 10.1016/j. jstrokecerebrovasdis.2012.09.008.
35. Hackett ML, Anderson CS. Predictors of depression after stroke: a systematic review of observational studies. Stroke. 2005;36:2296-2301. doi: 10.1161/01.STR.0000183622.75135.a4.
36. De Ryck A, Brouns R, Geurden M, Elseviers M, De Deyn PP, Engelborghs S. Risk factors for poststroke depression: identification of inconsistencies based on a systematic review. J Geriatr Psychiatry Neurol. 2014;27:147-158. doi: 10.1177/0891988714527514.
37. Parikh RM, Robinson RG, Lipsey JR, Starkstein SE, Fedoroff JP, Price TR. The impact of poststroke depression on recovery in activities of daily living over a 2-year follow-up. Arch Neurol. 1990;47:785-789.
38. Robinson RG, Bolla-Wilson K, Kaplan E, Lipsey JR, Price TR. Depression infuences intellectual impairment in stroke patients. Br J Psychiatry. 1986;148:541-547.
39. Wulsin L, Alwell K, Moomaw CJ, Lindsell CJ, Kleindorfer DO, Woo D, Flaherty ML, Khatri P, Adeoye O, Ferioli S, Broderick JP, Kissela BM. Comparison of two depression measures for predicting stroke outcomes. J Psychosom Res. 2012;72:175-179. doi: 10.1016/j. jpsychores.2011.11.015.
40. Chollet F, Tardy J, Albucher JF, Thalamas C, Berard E, Lamy C, Bejot Y, Deltour S, Jaillard A, Niclot P, Guillon B, Moulin T, Marque P, Pariente J, Arnaud C, Loubinoux I. Fluoxetine for motor recovery after acute isch-aemic stroke (FLAME): a randomised placebo-controlled trial. Lancet Neurol. 2011;10:123-130. doi: 10.1016/S1474-4422(10)70314-8.
41. Dam M, Tonin P, De Boni A, Pizzolato G, Casson S, Ermani M, Freo U, Piron L, Battistin L. Effects of fuoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy. Stroke. 1996;27:1211-1214.
42. Pariente J, Loubinoux I, Carel C, Albucher JF, Leger A, Manelfe C, Rascol O, Chollet F. Fluoxetine modulates motor performance and cerebral activation of patients recovering from stroke. Ann Neurol. 2001;50:718-729.
43. Zittel S, Weiller C, Liepert J. Citalopram improves dexterity in chronic stroke patients. Neurorehabil Neural Repair. 2008;22:311-314. doi: 10.1177/1545968307312173.
44. Acler M, Robol E, Fiaschi A, Manganotti P. A double-blind placebo RCT to investigate the effects of serotonergic modulation on brain excitability and motor recovery in stroke patients. J Neurol. 2009;256:1152-1158. doi: 10.1007/s00415-009-5093-7.
45. Mead GE, Hsieh CF, Lee R, Kutlubaev MA, Claxton A, Hankey GJ, Hackett ML. Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. Cochrane Database Syst Rev. 2012;11:CD009286. doi: 10.1002/14651858.CD009286.pub2.
46. Naess H, Waje-Andreassen U, Thomassen L, Nyland H, Myhr KM. Health-related quality of life among young adults with ischemic stroke on long-term follow-up. Stroke. 2006;37:1232-1236. doi: 10.1161/01. STR.0000217652.42273.02.
47. Paolucci S, Gandolfo C, Provinciali L, Torta R, Toso V; DESTRO Study Group. The Italian multicenter observational study on post-stroke depression (DESTRO). J Neurol. 2006;253:556-562. doi: 10.1007/ s00415-006-0058-6.
48. Christensen MC, Mayer SA, Ferran JM, Kissela B. Depressed mood after intracerebral hemorrhage: the FAST trial. Cerebrovasc Dis. 2009;27:353-360. doi: 10.1159/000202012.
49. Sturm JW, Donnan GA, Dewey HM, Macdonell RA, Gilligan AK, Srikanth V, Thrift AG. Quality of life after stroke: the North East Melbourne Stroke Incidence Study (NEMESIS). Stroke. 2004;35:2340-2345. doi: 10.1161/01.STR.0000141977.18520.3b.
50. Pan JH, Song XY, Lee SY, Kwok T. Longitudinal analysis of quality of life for stroke survivors using latent curve models. Stroke. 2008;39:2795-2802. doi: 10.1161/STROKEAHA.108.515460.
51. Williams LS, Bakas T, Brizendine E, Plue L, Tu W, Hendrie H, Kroenke K. How valid are family proxy assessments of stroke patients' health-related quality of life? Stroke. 2006;37:2081-2085. doi: 10.1161/01. STR.0000230583.10311.9f.
52. Jia H, Damush TM, Qin H, Ried LD, Wang X, Young LJ, Williams LS. The impact of poststroke depression on healthcare use by veterans with acute stroke. Stroke. 2006;37:2796-2801. doi: 10.1161/01. STR.0000244783.53274.a4.
53. Ghose SS, Williams LS, Swindle RW. Depression and other mental health diagnoses after stroke increase inpatient and outpatient medical utilization three years poststroke. Med Care. 2005;43:1259-1264.
54. Dossa A, Glickman ME, Berlowitz D. Association between mental health conditions and rehospitalization, mortality, and functional outcomes in patients with stroke following inpatient rehabilitation. BMC Health Serv Res. 2011;11:311. doi: 10.1186/1472-6963-11-311.
55. Blanchette CM, Simoni-Wastila L, Shaya F, Orwig D, Noel J, Stuart B. Health care use in depressed, elderly, cardiac patients and the effect of antidepressant use. Am J Health Syst Pharm. 2009;66:366-372. doi: 10.2146/ajhp080092.
56. Ayerbe L, Ayis S, Rudd AG, Heuschmann PU, Wolfe CD. Natural history, predictors, and associations of depression 5 years after stroke: the South London Stroke Register. Stroke. 2011;42:1907-1911. doi: 10.1161/STROKEAHA.110.605808.
57. Ayerbe L, Ayis S, Crichton SL, Rudd AG, Wolfe CD. Explanatory factors for the increased mortality of stroke patients with depression. Neurology. 2014;83:2007-2012. doi: 10.1212/WNL.0000000000001029.
58. Meader N, Moe-Byrne T, Llewellyn A, Mitchell AJ. Screening for post-stroke major depression: a meta-analysis of diagnostic validity studies. J Neurol Neurosurg Psychiatry. 2014;85:198-206. doi: 10.1136/ jnnp-2012-304194.
59. Whooley MA, Avins AL, Miranda J, Browner WS. Case-finding instruments for depression. Two questions are as good as many. J Gen Intern Med. 1997;12:439-445.
60. Turner A, Hambridge J, White J, Carter G, Clover K, Nelson L, Hackett M. Depression screening in stroke: a comparison of alternative measures with the structured diagnostic interview for the diagnostic and statistical manual of mental disorders, fourth edition (major depressive episode) as criterion standard. Stroke. 2012;43:1000-1005. doi: 10.1161/ STROKEAHA.111.643296.
61. de Man-van Ginkel JM, Hafsteinsdóttir T, Lindeman E, Burger H, Grobbee D, Schuurmans M. An effcient way to detect poststroke depression by subsequent administration of a 9-item and a 2-item Patient Health Questionnaire. Stroke. 2012;43:854-856. doi: 10.1161/STROKEAHA.111.640276.
62. Williams LS, Brizendine EJ, Plue L, Bakas T, Tu W, Hendrie H, Kroenke K. Performance of the PHQ-9 as a screening tool for depression after stroke. Stroke. 2005;36:635-638. doi: 10.1161/01.STR.0000155688.18207.33.
63. McManus D, Pipkin SS, Whooley MA. Screening for depression in patients with coronary heart disease (data from the Heart and Soul Study). Am J Cardiol. 2005;96:1076-1081. doi: 10.1016/j.amjcard.2005.06.037.
64. Dowrick C, Buchan I. Twelve month outcome of depression in general practice: does detection or disclosure make a difference? BMJ. 1995;311:1274-1276.
65. Callahan CM, Hendrie HC, Dittus RS, Brater DC, Hui SL, Tierney WM. Improving treatment of late life depression in primary care: a randomized clinical trial. J Am Geriatr Soc. 1994;42:839-846.
66. Williams JW Jr, Mulrow CD, Kroenke K, Dhanda R, Badgett RG, Omori D, Lee S. Case-finding for depression in primary care: a randomized trial. Am J Med. 1999;106:36-43.
67. Whooley MA, Stone B, Soghikian K. Randomized trial of case-fnd-ing for depression in elderly primary care patients. J Gen Intern Med. 2000;15:293-300.
68. Katon WJ, Lin EH, Von Korff M, Ciechanowski P, Ludman EJ, Young B, Peterson D, Rutter CM, McGregor M, McCulloch D. Collaborative care for patients with depression and chronic illnesses. N Engl J Med. 2010;363:2611-2620. doi: 10.1056/NEJMoa1003955.
69. Simon G. Collaborative care for depression. BMJ. 2006;332:249-250. doi: 10.1136/bmj.332.7536.249.
70. Archer J, Bower P, Gilbody S, Lovell K, Richards D, Gask L, Dickens C, Coventry P. Collaborative care for depression and anxiety problems. Cochrane Database Syst Rev. 2012;10:CD006525. doi: 10.1002/14651858.CD006525.pub2.
71. Katon W, Russo J, Lin EH, Schmittdiel J, Ciechanowski P, Ludman E, Peterson D, Young B, Von Korff M. Cost-effectiveness of a multicondition collaborative care intervention: a randomized controlled trial. Arch Gen Psychiatry. 2012;69:506-514. doi: 10.1001/archgenpsychiatry.2011.1548.
72. Siu AL, Bibbins-Domingo K, Grossman DC, Baumann LC, Davidson KW, Ebell M, García FA, Gillman M, Herzstein J, Kemper AR, Krist AH, Kurth AE, Owens DK, Phillips WR, Phipps MG, Pignone MP; US Preventive Services Task Force (USPSTF). Screening for depression in adults: US Preventive Services Task Force recommendation statement. JAMA. 2016;315:380-387. doi: 10.1001/jama.2015.18392.
73. Williams LS, Kroenke K, Bakas T, Plue LD, Brizendine E, Tu W, Hendrie H. Care management of poststroke depression: a randomized, controlled trial. Stroke. 2007;38:998-1003. doi: 10.1161/01. STR.0000257319.14023.61.
74. Williams LS, Ofner S, Yu Z, Beyth RJ, Plue L, Damush T. Pre-post evaluation of automated reminders may improve detection and management of post-stroke depression. J Gen Intern Med. 2011;26:852-857. doi: 10.1007/s11606-011-1709-6.
75. Duncan PW, Zorowitz R, Bates B, Choi JY, Glasberg JJ, Graham GD, Katz RC, Lamberty K, Reker D. Management of Adult Stroke Rehabilitation Care: a clinical practice guideline. Stroke. 2005;36:e100- e143. doi: 10.1161/01.STR.0000180861.54180.FF.
76. Miller EL, Murray L, Richards L, Zorowitz RD, Bakas T, Clark P, Billinger SA; on behalf of the American Heart Association Council on Cardiovascular Nursing and the Stroke Council. Comprehensive overview of nursing and interdisciplinary rehabilitation care of the stroke patient: a scientific statement from the American Heart Association. Stroke. 2010;41:2402-2448. doi: 10.1161/STR.0b013e3181e7512b.
77. Intercollegiate Stroke Working Party. National Clinic Guideline for Stroke. 4th ed. London: Royal College of Physicians; 2012.
78. Stroke Foundation of New Zealand and New Zealand Guidelines Group, Clinical Guidelines for Stroke Management 2010. Wellington, New Zealand: Stroke Foundation of New Zealand; 2010.
79. National Stroke Foundation. Clinical Guidelines for Stroke Management. Melbourne, Australia: National Stroke Foundation; 2010.
80. Berg A, Palomäki H, Lönnqvist J, Lehtihalmes M, Kaste M. Depression among caregivers of stroke survivors. Stroke. 2005;36:639-643. doi: 10.1161/01.STR.0000155690.04697.c0.
81. Schulz R, Beach SR. Caregiving as a risk factor for mortality: the Caregiver Health Effects Study. JAMA. 1999;282:2215-2219.
82. Ohtomo E, Hirai S, Terashi A, Hasegawa K, Tazaki Y, Araki G, Ito E, Nishimura T and Furukawa T. Clinical evaluation of aniracetam on psychiatric symptoms related to cerebrovascular disease. J Clin Exp Med. 1991;156:143-187.
83. Hackett ML, Anderson CS, House A, Xia J. Interventions for treating depression after stroke. Cochrane Database Syst Rev. 2008:CD003437.
84. Robinson RG, Jorge RE, Clarence-Smith K. Double-blind randomized treatment of poststroke depression using nefracetam. J Neuropsychiatry Clin Neurosci. 2008;20:178-184. doi: 10.1176/jnp.2008.20.2.178.
85. Grade C, Redford B, Chrostowski J, Toussaint L, Blackwell B. Methylphenidate in early poststroke recovery: a double-blind, placebo-controlled study. Arch Phys Med Rehabil. 1998;79:1047-1050.
86. Jorge RE, Moser DJ, Acion L, Robinson RG. Treatment of vascular depression using repetitive transcranial magnetic stimulation. Arch Gen Psychiatry. 2008;65:268-276. doi: 10.1001/archgenpsychiatry. 2007.45.
87. Mitchell PH, Veith RC, Becker KJ, Buzaitis A, Cain KC, Fruin M, Tirschwell D, Teri L. Brief psychosocial-behavioral intervention with antidepressant reduces poststroke depression signifcantly more than usual care with antidepressant: living well with stroke: randomized, controlled trial. Stroke. 2009;40:3073-3078. doi: 10.1161/ STROKEAHA.109.549808.
88. Kirkness CJ, Becker KJ, Cain KC, Kohen R, Tirschwell DL, Teri L, Veith RR and Mitchell PH. Telephone versus in-person psychosocial behavioral treatment in post-stroke depression. Stroke. 2015;46(suppl 1): AWP125.
89. Thomas SA, Walker MF, Macniven JA, Haworth H, Lincoln NB. Communication and Low Mood (CALM): a randomized controlled trial of behavioural therapy for stroke patients with aphasia. Clin Rehabil. 2013;27:398-408. doi: 10.1177/0269215512462227.
90. Alexopoulos GS, Wilkins VM, Marino P, Kanellopoulos D, Reding M, Sirey JA, Raue PJ, Ghosh S, O'Dell MW, Kiosses DN. Ecosystem focused therapy in poststroke depression: a preliminary study. Int J Geriatr Psychiatry. 2012;27:1053-1060. doi: 10.1002/gps.2822.
91. Ellis G, Mant J, Langhorne P, Dennis M, Winner S. Stroke liaison workers for stroke patients and carers: an individual patient data meta-analy-sis. Cochrane Database Syst Rev. 2010:CD005066.
92. Smith J, Forster A, Young J; Cochrane Group for information provision after stroke. Cochrane review: information provision for stroke patients and their caregivers. Clin Rehabil. 2009;23:195-206. doi: 10.1177/0269215508092820.
93. Parke HL, Epiphaniou E, Pearce G, Taylor SJ, Sheikh A, Griffths CJ, Greenhalgh T, Pinnock H. Self-management support interventions for stroke survivors: A systematic meta-review. PLoS One. 2015;10:e0131448. doi: 10.1371/journal.pone.0131448.
94. Jones F, Riazi A. Self-effcacy and self-management after stroke: a systematic review. Disabil Rehabil. 2011;33:797-810. doi: 10.3109/ 09638288.2010.511415.
95. Beekman AT, Smit F, Stek ML, Reynolds CF 3rd, Cuijpers PC. Preventing depression in high-risk groups. Curr Opin Psychiatry. 2010;23:8-11. doi: 10.1097/YCO.0b013e328333e17f.
96. Salter KL, Foley NC, Zhu L, Jutai JW, Teasell RW. Prevention of poststroke depression: does prophylactic pharmacotherapy work? J Stroke Cerebrovasc Dis. 2013;22:1243-1251. doi: 10.1016/j. jstrokecerebrovasdis.2012.03.013.
97. Hackett ML, Anderson CS, House A, Halteh C. Interventions for preventing depression after stroke. Cochrane Database Syst Rev. 2008:CD003689.
98. Tsai CS, Wu CL, Chou SY, Tsang HY, Hung TH, Su JA. Prevention of poststroke depression with milnacipran in patients with acute ischemic stroke: a double-blind randomized placebo-controlled trial. Int Clin Psychopharmacol. 2011;26:263-267. doi: 10.1097/ YIC.0b013e32834a5c64.
99. Robinson RG, Jorge RE, Moser DJ, Acion L, Solodkin A, Small SL, Fonzetti P, Hegel M, Arndt S. Escitalopram and problem-solving therapy for prevention of poststroke depression: a randomized controlled trial. JAMA. 2008;299:2391-2400. doi: 10.1001/jama.299.20.2391.
100. Xu J, Wang J, Liu J. Preventive effects of antidepressants on post-stroke depression. Chin Ment Health J. 2006;20:186-188.
101. Watkins CL, Wathan JV, Leathley MJ, Auton MF, Deans CF, Dickinson HA, Jack CI, Sutton CJ, van den Broek MD, Lightbody CE. The 12-month effects of early motivational interviewing after acute stroke: a randomized controlled trial. Stroke. 2011;42:1956-1961. doi: 10.1161/ STROKEAHA.110.602227.
102. Mikami K, Jorge RE, Moser DJ, Arndt S, Jang M, Solodkin A, Small SL, Fonzetti P, Hegel MT, Robinson RG. Increased frequency of frst-epi-sode poststroke depression after discontinuation of escitalopram. Stroke. 2011;42:3281-3283. doi: 10.1161/STROKEAHA.111.626507.