A switch in regulatory T cells through farm exposure during immune maturation in childhood

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 72, Issue 4, 2017, Pages 604-615

  Schroder P C ^a   Illi, S ^a   Casaca, V I ^a   Lluis, A ^b   Bock A ^a   Roduit, C ^c,d   Depner, M ^a   Frei, R ^d,e   Genuneit, J ^f   Pfefferle, P I ^g,h   Roponen, M ⁱ   Weber, J ^a   Braun Fahrlander C ^j,k   Riedler, J ^l,m   Dalphin, J C ⁿ   Pekkanen, J ^o,p   Lauener, R ^d,q   von Mutius, E ^a,h   Schaub, B ^a,h   Hyvärinen, Anne ^r   Karvonen, Anne M ^r   Hirvonen, Maija Riitta ^r   Tiittanen, Pekka ^r   Remes, Sami ^r   Kaulek, Vincent ^r   Dalphin, Marie Laure ^r   Ege, Markus J ^r   Loss, Georg J ^r   Renz, Harald ^r   Doekes, Gert ^r   Kabesch, Michael ^r   more..

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b DEPARTMENT OF MEDICINE   (United States)

^c UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^d Christine Kühne Center for Allergy Research and Education   (Switzerland)

^e UNIVERSITY OF ZURICH   (Switzerland)

^f UNIVERSITY OF ULM   (Germany)

^g PHILIPPS UNIVERSITY MARBURG   (Germany)

^h German Center for Lung Research (DZL)   (Germany)

ⁱ UNIVERSITY OF EASTERN FINLAND   (Finland)

^j SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^k UNIVERSITY OF BASEL   (Switzerland)

^l Schwarzach Hospital   (Austria)

^m PARACELSUS MEDICAL UNIVERSITY   (Austria)

ⁿ UNIVERSITY HOSPITAL OF BESANÇON   (France)

^o NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^p UNIVERSITY OF HELSINKI   (Finland)

^q Children's Hospital of Eastern Switzerland   (Switzerland)

^r German Centre for Lung Research ^*

more..

Author keywords

animal stable; asthma; farming; milk; regulatory T cells (Tregs)

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 5; INTERLEUKIN 9; IONOMYCIN; LIPOPOLYSACCHARIDE; PHORBOL 13 ACETATE 12 MYRISTATE; TRANSCRIPTION FACTOR FOXP3; ALLERGEN; BIOLOGICAL MARKER; CYTOKINE; IMMUNOGLOBULIN E; MESSENGER RNA;

ARTICLE; ASTHMA; CD4+ CD25+ T LYMPHOCYTE; CELL MATURATION; CHILD; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; EX VIVO STUDY; FEMALE; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUESTIONNAIRE; REGULATORY T LYMPHOCYTE; TH17 CELL; AGE; AGRICULTURAL LAND; ANIMAL; CLINICAL TRIAL; FOLLOW UP; GENE EXPRESSION; GENETICS; HEALTH SURVEY; IMMUNITY; IMMUNOLOGY; INFANT; LYMPHOCYTE COUNT; METABOLISM; MULTICENTER STUDY; NEWBORN; PREGNANCY; PRESCHOOL CHILD; T LYMPHOCYTE SUBPOPULATION;

AGE FACTORS; ALLERGENS; ANIMALS; ASTHMA; BIOMARKERS; CHILD; CHILD, PRESCHOOL; CYTOKINES; ENVIRONMENTAL EXPOSURE; FARMS; FEMALE; FOLLOW-UP STUDIES; GENE EXPRESSION; HUMANS; IMMUNITY; IMMUNOGLOBULIN E; INFANT; INFANT, NEWBORN; LYMPHOCYTE COUNT; MALE; PHENOTYPE; POPULATION SURVEILLANCE; PREGNANCY; RNA, MESSENGER; SURVEYS AND QUESTIONNAIRES; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY;

EID: 85003749687     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/all.13069     Document Type: Article

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