Engineering Aspergillus niger for galactaric acid production: Elimination of galactaric acid catabolism by using RNA sequencing and CRISPR/Cas9

Microbial Cell Factories

Volumn 15, Issue 1, 2016, Pages

  Kuivanen, Joosu ^a   Wang, Y M Jasmin ^a   Richard, Peter ^a  

^a VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

Author keywords

Aspergillus niger; CRISPR; d galacturonic acid; Galactaric acid; Metabolic engineering; Mucic acid; Pectin; Uronate dehydrogenase

Indexed keywords

DICARBOXYLIC ACID; GALACTARIC ACID; GALACTURONIC ACID; GUIDE RNA; OXIDOREDUCTASE; PECTIN; SINGLE CHIMERIC GUIDE RNA; UNCLASSIFIED DRUG; URONATE DEHYDROGENASE; SUGAR ACID;

ARTICLE; ASPERGILLUS NIGER; BIOPROCESS; CATABOLISM; CONTROLLED STUDY; CRISPR CAS SYSTEM; FUNGAL BIOMASS; GENE DELETION; HETEROLOGOUS EXPRESSION; METABOLIC ENGINEERING; NONHUMAN; RNA SEQUENCE; TRANSCRIPTOMICS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENETICS; METABOLISM; PROCEDURES; SEQUENCE ANALYSIS;

ASPERGILLUS NIGER; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; METABOLIC ENGINEERING; SEQUENCE ANALYSIS, RNA; SUGAR ACIDS;

EID: 85003707555     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-016-0613-5     Document Type: Article

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