Inflammatory bowel disease is associated with an increased risk of inflammatory skin diseases: A population-based cross-sectional study

Journal of the American Academy of Dermatology

Volumn 76, Issue 1, 2017, Pages 40-48

  Kim, Miri ^a   Choi, Kwang Hyun ^b   Hwang, Se Won ^a   Lee, Young Bok ^a   Park, Hyun Jeong ^a   Bae, Jung Min ^a  

^a The Catholic University of Korea   (South Korea)

^b Veterans Health Service Medical Center   (South Korea)

Author keywords

atopic dermatitis; epidemiology; inflammatory bowel disease; psoriasis; rosacea

Indexed keywords

ADOLESCENT; ADULT; AGED; ALOPECIA AREATA; ARTICLE; ATOPIC DERMATITIS; CHILD; CLINICAL EVALUATION; CONTROLLED STUDY; CROHN DISEASE; CROSS-SECTIONAL STUDY; DATA BASE; DISEASE ASSOCIATION; FEMALE; HUMAN; INFECTION RISK; KOREA; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OUTCOME ASSESSMENT; PATIENT RISK; PRIORITY JOURNAL; PSORIASIS; RISK ASSESSMENT; RISK FACTOR; ROSACEA; ULCERATIVE COLITIS; VERY ELDERLY; VITILIGO; YOUNG ADULT; AGE; CASE CONTROL STUDY; COLITIS, ULCERATIVE; DERMATITIS, ATOPIC; SEX DIFFERENCE; SKIN DISEASES; SOUTH KOREA;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ALOPECIA AREATA; CASE-CONTROL STUDIES; CHILD; COLITIS, ULCERATIVE; CROHN DISEASE; CROSS-SECTIONAL STUDIES; DERMATITIS, ATOPIC; FEMALE; HUMANS; MALE; MIDDLE AGED; PSORIASIS; REPUBLIC OF KOREA; ROSACEA; SEX FACTORS; SKIN DISEASES; VITILIGO; YOUNG ADULT;

EID: 85002947473     PISSN: 01909622     EISSN: 10976787     Source Type: Journal    
DOI: 10.1016/j.jaad.2016.08.022     Document Type: Article

References (53)

1. 1 Sartor, R.B., Pathogenesis and immune mechanisms of chronic inflammatory bowel diseases. Am J Gastroenterol 92 (1997), 5s–11s.
2. 2 Brown, S.J., Mayer, L., The immune response in inflammatory bowel disease. Am J Gastroenterol 102 (2007), 2058–2069.
3. 3 Cohen, A.D., Dreiher, J., Birkenfeld, S., Psoriasis associated with ulcerative colitis and Crohn's disease. J Eur Acad Dermatol Venereol 23 (2009), 561–565.
4. 4 Spoendlin, J., Karatas, G., Furlano, R.I., Jick, S.S., Meier, C.R., Rosacea in patients with ulcerative colitis and Crohn's disease: a population-based case-control study. Inflamm Bowel Dis 22 (2016), 680–687.
5. 5 Schmitt, J., Schwarz, K., Baurecht, H., et al. Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes. J Allergy Clin Immunol 137 (2016), 130–136.
6. 6 Lee, F.I., Bellary, S.V., Francis, C., Increased occurrence of psoriasis in patients with Crohn's disease and their relatives. Am J Gastroenterol 85 (1990), 962–963.
7. 7 Bernstein, C.N., Wajda, A., Blanchard, J.F., The clustering of other chronic inflammatory diseases in inflammatory bowel disease: a population-based study. Gastroenterology 129 (2005), 827–836.
8. 8 Yates, V.M., Watkinson, G., Kelman, A., Further evidence for an association between psoriasis, Crohn's disease and ulcerative colitis. Br J Dermatol 106 (1982), 323–330.
9. 9 Egeberg A, Mallbris L, Warren RB, et al. Association between psoriasis and inflammatory bowel disease - a Danish nationwide cohort study. Br J Dermatol. http://dx.doi.org/10.1111/bjd.14528. Published online June 20, 2016.
10. 10 Asarch, A., Barak, O., Loo, D.S., Gottlieb, A.B., Th17 cells: a new paradigm for cutaneous inflammation. J Dermatolog Treat 19 (2008), 259–266.
11. 11 Fitch, E., Harper, E., Skorcheva, I., Kurtz, S.E., Blauvelt, A., Pathophysiology of psoriasis: recent advances on IL-23 and Th17 cytokines. Curr Rheumatol Rep 9 (2007), 461–467.
12. 12 Fujino, S., Andoh, A., Bamba, S., et al. Increased expression of interleukin 17 in inflammatory bowel disease. Gut 52 (2003), 65–70.
13. 13 Song, L., Zhou, R., Huang, S., et al. High intestinal and systemic levels of interleukin-23/T-helper 17 pathway in Chinese patients with inflammatory bowel disease. Mediators Inflamm, 2013, 2013, 425915.
14. 14 Skroza, N., Proietti, I., Pampena, R., et al. Correlations between psoriasis and inflammatory bowel diseases. Biomed Res Int, 2013, 2013, 983902.
15. 15 Lee, E., Trepicchio, W.L., Oestreicher, J.L., et al. Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris. J Exp Med 199 (2004), 125–130.
16. 16 Sabat, R., Philipp, S., Hoflich, C., et al. Immunopathogenesis of psoriasis. Exp Dermatol 16 (2007), 779–798.
17. 17 Cargill, M., Schrodi, S.J., Chang, M., et al. A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet 80 (2007), 273–290.
18. 18 Smith, R.L., Warren, R.B., Eyre, S., et al. Polymorphisms in the IL-12beta and IL-23R genes are associated with psoriasis of early onset in a UK cohort. J Invest Dermatol 128 (2008), 1325–1327.
19. 19 Kim, S.W., Kim, E.S., Moon, C.M., et al. Genetic polymorphisms of IL-23R and IL-17A and novel insights into their associations with inflammatory bowel disease. Gut 60 (2011), 1527–1536.
20. 20 Harris, K.A., Horst, S., Gadani, A., et al. Patients with refractory Crohn's disease successfully treated with ustekinumab. Inflamm Bowel Dis 22 (2016), 397–401.
21. 21 Li, W.Q., Cho, E., Khalili, H., Wu, S., Chan, A.T., Qureshi, A.A., Rosacea, use of tetracycline, and risk of incident inflammatory bowel disease in women. Clin Gastroenterol Hepatol 14 (2016), 220–225.e3.
22. 22 Buhl, T., Sulk, M., Nowak, P., et al. Molecular and morphological characterization of inflammatory infiltrate in rosacea reveals activation of Th1/Th17 pathways. J Invest Dermatol 135 (2015), 2198–2208.
23. 23 El-Tawil, A.M., A population-based case-control study of potential risk factors for IBD. Am J Gastroenterol, 104, 2009, 1064.
24. 24 Kim, M., Kim, K.E., Jung, H.Y., et al. Recombinant erythroid differentiation regulator 1 inhibits both inflammation and angiogenesis in a mouse model of rosacea. Exp Dermatol 24 (2015), 680–685.
25. 25 Schauber, J., Rieger, D., Weiler, F., et al. Heterogeneous expression of human cathelicidin hCAP18/LL-37 in inflammatory bowel diseases. Eur J Gastroenterol Hepatol 18 (2006), 615–621.
26. 26 Goyette, P., Boucher, G., Mallon, D., et al. High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis. Nat Genet 47 (2015), 172–179.
27. 27 Chang, A.L., Raber, I., Xu, J., et al. Assessment of the genetic basis of rosacea by genome-wide association study. J Invest Dermatol 135 (2015), 1548–1555.
28. 28 Reinholz, M., Ruzicka, T., Schauber, J., Cathelicidin LL-37: an antimicrobial peptide with a role in inflammatory skin disease. Ann Dermatol 24 (2012), 126–135.
29. 29 Weidinger, S., Novak, N., Atopic dermatitis. Lancet 387 (2016), 1109–1122.
30. 30 Saeki, H., Tsunemi, Y., Fujita, H., et al. Prevalence of atopic dermatitis determined by clinical examination in Japanese adults. J Dermatol 33 (2006), 817–819.
31. 31 Sugiura, H., Umemoto, N., Deguchi, H., et al. Prevalence of childhood and adolescent atopic dermatitis in a Japanese population: comparison with the disease frequency examined 20 years ago. Acta Derm Venereol 78 (1998), 293–294.
32. 32 Bae, J.M., Choi, Y.Y., Park, C.O., Chung, K.Y., Lee, K.H., Efficacy of allergen-specific immunotherapy for atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials. J Allergy Clin Immunol 132 (2013), 110–117.
33. 33 Noh, S., Park, C.O., Bae, J.M., et al. Lower vitamin D status is closely correlated with eczema of the head and neck. J Allergy Clin Immunol 133 (2014), 1767–1770.e6.
34. 34 Koga, C., Kabashima, K., Shiraishi, N., Kobayashi, M., Tokura, Y., Possible pathogenic role of Th17 cells for atopic dermatitis. J Invest Dermatol 128 (2008), 2625–2630.
35. 35 Noda, S., Suarez-Farinas, M., Ungar, B., et al. The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization. J Allergy Clin Immunol 136 (2015), 1254–1264.
36. 36 Gill, L., Zarbo, A., Isedeh, P., Jacobsen, G., Lim, H.W., Hamzavi, I., Comorbid autoimmune diseases in patients with vitiligo: a cross-sectional study. J Am Acad Dermatol 74 (2016), 295–302.
37. 37 Lee, H., Lee, M.H., Lee, D.Y., et al. Prevalence of vitiligo and associated comorbidities in Korea. Yonsei Med J 56 (2015), 719–725.
38. 38 Lew, B.L., Cho, H.R., Haw, S., Kim, H.J., Chung, J.H., Sim, W.Y., Association between IL17A/IL17RA gene polymorphisms and susceptibility to alopecia areata in the Korean population. Ann Dermatol 24 (2012), 61–65.
39. 39 Laberge, G., Mailloux, C.M., Gowan, K., et al. Early disease onset and increased risk of other autoimmune diseases in familial generalized vitiligo. Pigment Cell Res 18 (2005), 300–305.
40. 40 Schallreuter, K.U., Lemke, R., Brandt, O., et al. Vitiligo and other diseases: coexistence or true association? Hamburg study on 321 patients. Dermatology 188 (1994), 269–275.
41. 41 Chen, Y.T., Chen, Y.J., Hwang, C.Y., et al. Comorbidity profiles in association with vitiligo: a nationwide population-based study in Taiwan. J Eur Acad Dermatol Venereol 29 (2015), 1362–1369.
42. 42 Chu, S.Y., Chen, Y.J., Tseng, W.C., et al. Comorbidity profiles among patients with alopecia areata: the importance of onset age, a nationwide population-based study. J Am Acad Dermatol 65 (2011), 949–956.
43. 43 Ettefagh, L., Nedorost, S., Mirmirani, P., Alopecia areata in a patient using infliximab: new insights into the role of tumor necrosis factor on human hair follicles. Arch Dermatol, 140, 2004, 1012.
44. 44 Garcia Bartels, N., Lee, H.H., Worm, M., Burmester, G.R., Sterry, W., Blume-Peytavi, U., Development of alopecia areata universalis in a patient receiving adalimumab. Arch Dermatol 142 (2006), 1654–1655.
45. 45 Patel, K.V., Sanderson, J.D., Irving, P.M., Alopecia areata: a possible extraintestinal manifestation of Crohn's disease. J Crohns Colitis, 7, 2013, e503.
46. 46 Safina, D.D., Abdulkhakov, R.A., Abdulkhakov, S.R., Odintsova, A., Cheremina, N.A., Clinical case of a combination of ulcerative colitis and alopecia areata. [in Russian] Eksp Klin Gastroenterol, 2013, 92–96.
47. 47 Patel, K.V., Farrant, P., Sanderson, J.D., Irving, P.M., Hair loss in patients with inflammatory bowel disease. Inflamm Bowel Dis 19 (2013), 1753–1763.
48. 48 Thomas, E.A., Kadyan, R.S., Alopecia areata and autoimmunity: a clinical study. Indian J Dermatol 53 (2008), 70–74.
49. 49 Gruppo Italiano Studi Epidemiologici in Dermatologia, Epidemiological evidence of the association between lichen planus and two immune-related diseases: alopecia areata and ulcerative colitis. Arch Dermatol 127 (1991), 688–691.
50. 50 Goh, C., Finkel, M., Christos, P.J., Sinha, A.A., Profile of 513 patients with alopecia areata: associations of disease subtypes with atopy, autoimmune disease and positive family history. J Eur Acad Dermatol Venereol 20 (2006), 1055–1060.
51. 51 Picco, M.F., Zubiaurre, I., Adluni, M., Cangemi, J.R., Shelton, D., Immunomodulators are associated with a lower risk of first surgery among patients with non-penetrating non-stricturing Crohn's disease. Am J Gastroenterol 104 (2009), 2754–2759.
52. 52 Flasar, M.H., Chao, J., Ozbay, A.B., Skup, M., Lu, M., Cross, R., Biological and immunomodulator use in Crohn's disease in a Medicaid population. Inflamm Bowel Dis 22 (2016), 1056–1064.
53. 53 Lolli, E., Saraceno, R., Calabrese, E., et al. Psoriasis phenotype in inflammatory bowel disease: a case-control prospective study. J Crohns Colitis 9 (2015), 699–707.