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Volumn 126, Issue 12, 2016, Pages 4404-4416

MicroRNA-29b mediates altered innate immune development in acute leukemia

(19)  Mundy Bosse, Bethany L a   Scoville, Steven D b   Chen, Li a   McConnell, Kathleen a   Mao, Hsiaoyin C a   Ahmed, Elshafa H a   Zorko, Nicholas c   Harvey, Sophia d   Cole, Jordan e   Zhang, Xiaoli f   Costinean, Stefan g   Croce, Carlo M h,i   Larkin, Karilyn a   Byrd, John C a,i   Vasu, Sumithira a,i   Blum, William a,i   Yu, Jianhua a,i   Freud, Aharon G a,i   Caligiuri, Michael A a,h  


Author keywords

[No Author keywords available]

Indexed keywords

GRANZYME B; MICRORNA 29B; PERFORIN; EOMES PROTEIN, HUMAN; EOMES PROTEIN, MOUSE; GRANZYME; GZMB PROTEIN, MOUSE; MICRORNA; MIRN29 MICRORNA, HUMAN; MIRN29 MICRORNA, MOUSE; RNA; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21; TUMOR PROTEIN;

EID: 85002851532     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI85413     Document Type: Article
Times cited : (54)

References (62)
  • 1
    • 85002804184 scopus 로고    scopus 로고
    • SEER Cancer Statistics Review, 1975-2012. National Cancer Institute Published April 2015. Accessed September 20, 2016
    • SEER Cancer Statistics Review, 1975-2012. National Cancer Institute. http://seer.cancer.gov/csr/1975-2012. Published April 2015. Accessed September 20, 2016.
  • 2
    • 84888428219 scopus 로고    scopus 로고
    • Location and cellular stages of natural killer cell development
    • Yu J, Freud AG, Caligiuri M.A. Location and cellular stages of natural killer cell development. Trends Immunol. 2013;34(12):573-582.
    • (2013) Trends Immunol. , vol.34 , Issue.12 , pp. 573-582
    • Yu, J.1    Freud, A.G.2    Caligiuri, M.A.3
  • 3
    • 20144388509 scopus 로고    scopus 로고
    • Successful adoptive transfer and in vivo expansion of human haploiden-tical NK cells in patients with cancer
    • Miller JS, et al. Successful adoptive transfer and in vivo expansion of human haploiden-tical NK cells in patients with cancer. Blood. 2005;105(8):3051-3057.
    • (2005) Blood. , vol.105 , Issue.8 , pp. 3051-3057
    • Miller, J.S.1
  • 4
    • 0037086131 scopus 로고    scopus 로고
    • Effectiveness of donor natural killer cell alloreactivity in mis-matched hematopoietic transplants
    • Ruggeri L, et al. Effectiveness of donor natural killer cell alloreactivity in mis-matched hematopoietic transplants. Science. 2002;295(5562):2097-2100.
    • (2002) Science. , vol.295 , Issue.5562 , pp. 2097-2100
    • Ruggeri, L.1
  • 5
    • 0025215573 scopus 로고
    • Loss of natural killer activity as an indicator of relapse in acute leukaemia
    • Tratkiewicz JA, Szer J. Loss of natural killer activity as an indicator of relapse in acute leukaemia. Clin Exp Immunol. 1990;80(2):241-246.
    • (1990) Clin Exp Immunol. , vol.80 , Issue.2 , pp. 241-246
    • Tratkiewicz, J.A.1    Szer, J.2
  • 6
    • 0027368830 scopus 로고
    • Role of natural killer cells in cancer
    • Pross HF, Lotzová E. Role of natural killer cells in cancer. Nat Immun. 1993;12(4-5):279-292.
    • (1993) Nat Immun. , vol.12 , Issue.4-5 , pp. 279-292
    • Pross, H.F.1    Lotzová, E.2
  • 7
    • 0029887832 scopus 로고    scopus 로고
    • Natural killer cell activity and cytokine production as prognostic factors in adult acute leukemia
    • Tajima F, Kawatani T, Endo A, Kawasaki H. Natural killer cell activity and cytokine production as prognostic factors in adult acute leukemia. Leukemia. 1996;10(3):478-482.
    • (1996) Leukemia. , vol.10 , Issue.3 , pp. 478-482
    • Tajima, F.1    Kawatani, T.2    Endo, A.3    Kawasaki, H.4
  • 9
    • 0041737499 scopus 로고    scopus 로고
    • Functional expression and release of ligands for the activating immu-noreceptor NKG2D in leukemia
    • Salih HR, et al. Functional expression and release of ligands for the activating immu-noreceptor NKG2D in leukemia. Blood. 2003;102(4):1389-1396.
    • (2003) Blood. , vol.102 , Issue.4 , pp. 1389-1396
    • Salih, H.R.1
  • 10
    • 38949193232 scopus 로고    scopus 로고
    • NKG2D ligand expression in AML increases in response to HDAC inhibitor valproic acid and contributes to allorecognition by NK-cell lines with single KIR-HLA class i specificities
    • Diermayr S, et al. NKG2D ligand expression in AML increases in response to HDAC inhibitor valproic acid and contributes to allorecognition by NK-cell lines with single KIR-HLA class I specificities. Blood. 2008;111(3):1428-1436.
    • (2008) Blood. , vol.111 , Issue.3 , pp. 1428-1436
    • Diermayr, S.1
  • 11
    • 77957734984 scopus 로고    scopus 로고
    • Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia
    • Cooley S, et al. Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia. Blood. 2010;116(14):2411-2419.
    • (2010) Blood. , vol.116 , Issue.14 , pp. 2411-2419
    • Cooley, S.1
  • 12
    • 70349561448 scopus 로고    scopus 로고
    • PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model
    • Zhang L, Gajewski TF, Kline J. PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model. Blood. 2009;114(8):1545-1552.
    • (2009) Blood. , vol.114 , Issue.8 , pp. 1545-1552
    • Zhang, L.1    Gajewski, T.F.2    Kline, J.3
  • 13
    • 84905375431 scopus 로고    scopus 로고
    • The stimulation of PD-L1-specific cytotoxic T lymphocytes can both directly and indirectly enhance antileu-kemic immunity
    • Ahmad SM, Svane IM, Andersen MH. The stimulation of PD-L1-specific cytotoxic T lymphocytes can both directly and indirectly enhance antileu-kemic immunity. Blood Cancer J. 2014;4:e230.
    • (2014) Blood Cancer J. , vol.4 , pp. e230
    • Ahmad, S.M.1    Svane, I.M.2    Andersen, M.H.3
  • 14
    • 33344466283 scopus 로고    scopus 로고
    • CTLA-4 blockade by a human MAb enhances the capacity of AML-derived DC to induce T-cell responses against AML cells in an autologous culture sys-tem
    • Zhong RK, Loken M, Lane TA, Ball ED. CTLA-4 blockade by a human MAb enhances the capacity of AML-derived DC to induce T-cell responses against AML cells in an autologous culture sys-tem. Cytotherapy. 2006;8(1):3-12.
    • (2006) Cytotherapy. , vol.8 , Issue.1 , pp. 3-12
    • Zhong, R.K.1    Loken, M.2    Lane, T.A.3    Ball, E.D.4
  • 15
    • 67349221158 scopus 로고    scopus 로고
    • HLA-E upregulation on IFN-gamma-activated AML blasts impairs CD94/NKG2A-dependent NK cytolysis after haplo-mismatched hematopoietic SCT
    • Nguyen S, et al. HLA-E upregulation on IFN-gamma-activated AML blasts impairs CD94/NKG2A-dependent NK cytolysis after haplo-mismatched hematopoietic SCT. Bone Marrow Transplant. 2009;43(9):693-699.
    • (2009) Bone Marrow Transplant. , vol.43 , Issue.9 , pp. 693-699
    • Nguyen, S.1
  • 16
    • 84869819029 scopus 로고    scopus 로고
    • A phase 1 trial of the anti-KIR antibody IPH2101 in patients with relapsed/refractory multiple myeloma
    • Benson DM, et al. A phase 1 trial of the anti-KIR antibody IPH2101 in patients with relapsed/refractory multiple myeloma. Blood. 2012;120(22):4324-4333.
    • (2012) Blood. , vol.120 , Issue.22 , pp. 4324-4333
    • Benson, D.M.1
  • 17
    • 31144449386 scopus 로고    scopus 로고
    • CD27 dissects mature NK cells into two subsets with distinct responsiveness and migratory capacity
    • Hayakawa Y, Smyth MJ. CD27 dissects mature NK cells into two subsets with distinct responsiveness and migratory capacity. J Immunol. 2006;176(3):1517-1524.
    • (2006) J Immunol. , vol.176 , Issue.3 , pp. 1517-1524
    • Hayakawa, Y.1    Smyth, M.J.2
  • 18
    • 67049114093 scopus 로고    scopus 로고
    • Maturation of mouse NK cells is a 4-stage developmental program
    • Chiossone L, Chaix J, Fuseri N, Roth C, Vivier E, Walzer T. Maturation of mouse NK cells is a 4-stage developmental program. Blood. 2009;113(22):5488-5496.
    • (2009) Blood. , vol.113 , Issue.22 , pp. 5488-5496
    • Chiossone, L.1    Chaix, J.2    Fuseri, N.3    Roth, C.4    Vivier, E.5    Walzer, T.6
  • 19
    • 50949124847 scopus 로고    scopus 로고
    • Human natural killer cells
    • Caligiuri M.A. Human natural killer cells. Blood. 2008;112(3):461-469.
    • (2008) Blood. , vol.112 , Issue.3 , pp. 461-469
    • Caligiuri, M.A.1
  • 20
    • 84897958959 scopus 로고    scopus 로고
    • Human natural killer cell development in secondary lymphoid tissues
    • Freud AG, Yu J, Caligiuri M.A. Human natural killer cell development in secondary lymphoid tissues. Semin Immunol. 2014;26(2):132-137.
    • (2014) Semin Immunol. , vol.26 , Issue.2 , pp. 132-137
    • Freud, A.G.1    Yu, J.2    Caligiuri, M.A.3
  • 21
    • 1842785209 scopus 로고    scopus 로고
    • T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells
    • Townsend MJ, et al. T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells. Immunity. 2004;20(4):477-494.
    • (2004) Immunity. , vol.20 , Issue.4 , pp. 477-494
    • Townsend, M.J.1
  • 22
    • 84862777436 scopus 로고    scopus 로고
    • The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation
    • Gordon SM, et al. The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation. Immunity. 2012;36(1):55-67.
    • (2012) Immunity. , vol.36 , Issue.1 , pp. 55-67
    • Gordon, S.M.1
  • 23
    • 80051890269 scopus 로고    scopus 로고
    • MicroRNA-29 regulates T-box transcription factors and interfer-on-? Production in helper T cells
    • Steiner DF, et al. MicroRNA-29 regulates T-box transcription factors and interfer-on-? production in helper T cells. Immunity. 2011;35(2):169-181.
    • (2011) Immunity. , vol.35 , Issue.2 , pp. 169-181
    • Steiner, D.F.1
  • 24
    • 84941776166 scopus 로고    scopus 로고
    • MicroRNA-15/16 antagonizes Myb to control NK cell maturation
    • Sullivan RP, et al. MicroRNA-15/16 antagonizes Myb to control NK cell maturation. J Immunol. 2015;195(6):2806-2817.
    • (2015) J Immunol. , vol.195 , Issue.6 , pp. 2806-2817
    • Sullivan, R.P.1
  • 25
    • 80052033649 scopus 로고    scopus 로고
    • The microRNA miR-29 controls innate and adaptive immune responses to intra-cellular bacterial infection by targeting interfer-on-?
    • Ma F, et al. The microRNA miR-29 controls innate and adaptive immune responses to intra-cellular bacterial infection by targeting interfer-on-?. Nat Immunol. 2011;12(9):861-869.
    • (2011) Nat Immunol. , vol.12 , Issue.9 , pp. 861-869
    • Ma, F.1
  • 26
    • 84925300700 scopus 로고    scopus 로고
    • Micro-RNA management of NK-cell developmental and functional programs
    • Leong JW, Sullivan RP, Fehniger TA. micro-RNA management of NK-cell developmental and functional programs. Eur J Immunol. 2014;44(10):2862-2868.
    • (2014) Eur J Immunol. , vol.44 , Issue.10 , pp. 2862-2868
    • Leong, J.W.1    Sullivan, R.P.2    Fehniger, T.A.3
  • 27
    • 84864812650 scopus 로고    scopus 로고
    • MiR-29ab1 deficiency identifies a negative feedback loop controlling Th1 bias that is dysregulated in multiple sclerosis
    • Smith KM, et al. miR-29ab1 deficiency identifies a negative feedback loop controlling Th1 bias that is dysregulated in multiple sclerosis. J Immunol. 2012;189(4):1567-1576.
    • (2012) J Immunol. , vol.189 , Issue.4 , pp. 1567-1576
    • Smith, K.M.1
  • 28
    • 84892879433 scopus 로고    scopus 로고
    • Eradicating acute myeloid leukemia in a Mll(PTD/wt):Flt3(ITD/wt) murine model: A path to novel therapeutic approaches for human disease
    • Bernot KM, et al. Eradicating acute myeloid leukemia in a Mll(PTD/wt):Flt3(ITD/wt) murine model: a path to novel therapeutic approaches for human disease. Blood. 2013;122(23):3778-3783.
    • (2013) Blood. , vol.122 , Issue.23 , pp. 3778-3783
    • Bernot, K.M.1
  • 29
    • 0037093066 scopus 로고    scopus 로고
    • Defective expression and function of natural killer cell-triggering receptors in patients with acute myeloid leukemia
    • Costello RT, et al. Defective expression and function of natural killer cell-triggering receptors in patients with acute myeloid leukemia. Blood. 2002;99(10):3661-3667.
    • (2002) Blood. , vol.99 , Issue.10 , pp. 3661-3667
    • Costello, R.T.1
  • 30
    • 49649107807 scopus 로고    scopus 로고
    • An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation
    • Dulphy N, et al. An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation. J Immunol. 2008;181(3):2227-2237.
    • (2008) J Immunol. , vol.181 , Issue.3 , pp. 2227-2237
    • Dulphy, N.1
  • 31
    • 28544432065 scopus 로고    scopus 로고
    • Activated natural killer cells from patients with acute myeloid leukemia are cytotoxic against autologous leukemic blasts in NOD/SCID mice
    • Siegler U, Kalberer CP, Nowbakht P, Sendelov S, Meyer-Monard S, Wodnar-Filipowicz A. Activated natural killer cells from patients with acute myeloid leukemia are cytotoxic against autologous leukemic blasts in NOD/SCID mice. Leukemia. 2005;19(12):2215-2222.
    • (2005) Leukemia. , vol.19 , Issue.12 , pp. 2215-2222
    • Siegler, U.1    Kalberer, C.P.2    Nowbakht, P.3    Sendelov, S.4    Meyer-Monard, S.5    Wodnar-Filipowicz, A.6
  • 32
    • 0036079077 scopus 로고    scopus 로고
    • In vivo developmental stages in murine natural killer cell maturation
    • Kim S, et al. In vivo developmental stages in murine natural killer cell maturation. Nat Immunol. 2002;3(6):523-528.
    • (2002) Nat Immunol. , vol.3 , Issue.6 , pp. 523-528
    • Kim, S.1
  • 33
    • 34247170073 scopus 로고    scopus 로고
    • NK cell maturation and peripheral homeostasis is associated with KLRG1 up-regulation
    • Huntington ND, et al. NK cell maturation and peripheral homeostasis is associated with KLRG1 up-regulation. J Immunol. 2007;178(8):4764-4770.
    • (2007) J Immunol. , vol.178 , Issue.8 , pp. 4764-4770
    • Huntington, N.D.1
  • 34
    • 84899760855 scopus 로고    scopus 로고
    • Leukemia-induced pheno-typic and functional defects in natural killer cells predict failure to achieve remission in acute myeloid leukemia
    • Stringaris K, et al. Leukemia-induced pheno-typic and functional defects in natural killer cells predict failure to achieve remission in acute myeloid leukemia. Haematologica. 2014;99(5):836-847.
    • (2014) Haematologica. , vol.99 , Issue.5 , pp. 836-847
    • Stringaris, K.1
  • 35
    • 33845987986 scopus 로고    scopus 로고
    • Deficient expression of NCR in NK cells from acute myeloid leukemia: Evolution during leukemia treatment and impact of leukemia cells in NCRdull phenotype induction
    • Fauriat C, et al. Deficient expression of NCR in NK cells from acute myeloid leukemia: Evolution during leukemia treatment and impact of leukemia cells in NCRdull phenotype induction. Blood. 2007;109(1):323-330.
    • (2007) Blood. , vol.109 , Issue.1 , pp. 323-330
    • Fauriat, C.1
  • 36
    • 59149095895 scopus 로고    scopus 로고
    • Glucocorticoid-induced tumor necrosis factor receptor-related protein ligand subverts immunosurveillance of acute myeloid leukemia in humans
    • Baessler T, et al. Glucocorticoid-induced tumor necrosis factor receptor-related protein ligand subverts immunosurveillance of acute myeloid leukemia in humans. Cancer Res. 2009;69(3):1037-1045.
    • (2009) Cancer Res. , vol.69 , Issue.3 , pp. 1037-1045
    • Baessler, T.1
  • 37
    • 4344669257 scopus 로고    scopus 로고
    • Prevalence and clinical significance of resistance to perforin-and FAS-mediated cell death in leukemia
    • Otten HG, van Ginkel WG, Hagenbeek A, Petersen EJ. Prevalence and clinical significance of resistance to perforin-and FAS-mediated cell death in leukemia. Leukemia. 2004;18(8):1401-1405.
    • (2004) Leukemia. , vol.18 , Issue.8 , pp. 1401-1405
    • Otten, H.G.1    Van Ginkel, W.G.2    Hagenbeek, A.3    Petersen, E.J.4
  • 38
    • 0034661878 scopus 로고    scopus 로고
    • Impaired binding of perforin on the surface of tumor cells is a cause of target cell resistance against cytotoxic effector cells
    • Lehmann C, Zeis M, Schmitz N, Uharek L. Impaired binding of perforin on the surface of tumor cells is a cause of target cell resistance against cytotoxic effector cells. Blood. 2000;96(2):594-600.
    • (2000) Blood. , vol.96 , Issue.2 , pp. 594-600
    • Lehmann, C.1    Zeis, M.2    Schmitz, N.3    Uharek, L.4
  • 39
    • 84941788007 scopus 로고    scopus 로고
    • Defective NK cells in acute myeloid leukemia patients at diagnosis are associated with blast transcriptional signatures of immune evasion
    • Khaznadar Z, et al. Defective NK cells in acute myeloid leukemia patients at diagnosis are associated with blast transcriptional signatures of immune evasion. J Immunol. 2015;195(6):2580-2590.
    • (2015) J Immunol. , vol.195 , Issue.6 , pp. 2580-2590
    • Khaznadar, Z.1
  • 40
    • 0035874522 scopus 로고    scopus 로고
    • Human natural killer cells: A unique innate immunoregulatory role for the CD56(bright) subset
    • Cooper MA, et al. Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subset. Blood. 2001;97(10):3146-3151.
    • (2001) Blood. , vol.97 , Issue.10 , pp. 3146-3151
    • Cooper, M.A.1
  • 41
    • 78851472118 scopus 로고    scopus 로고
    • Pre-eminence and per-sistence of immature natural killer cells in acute myeloid leukemia patients in first complete remission
    • Dauguet N, Récher C, Demur C, Fournié JJ, Poupot M, Poupot R. Pre-eminence and per-sistence of immature natural killer cells in acute myeloid leukemia patients in first complete remission. Am J Hematol. 2011;86(2):209-213.
    • (2011) Am J Hematol. , vol.86 , Issue.2 , pp. 209-213
    • Dauguet, N.1    Récher, C.2    Demur, C.3    Fournié, J.J.4    Poupot, M.5    Poupot, R.6
  • 42
    • 33750686595 scopus 로고    scopus 로고
    • Human natural killer cell development
    • Freud AG, Caligiuri M.A. Human natural killer cell development. Immunol Rev. 2006;214:56-72.
    • (2006) Immunol Rev. , vol.214 , pp. 56-72
    • Freud, A.G.1    Caligiuri, M.A.2
  • 43
    • 73949118737 scopus 로고    scopus 로고
    • MicroRNA 29b func-tions in acute myeloid leukemia
    • Garzon R, et al. MicroRNA 29b func-tions in acute myeloid leukemia. Blood. 2009;114(26):5331-5341.
    • (2009) Blood. , vol.114 , Issue.26 , pp. 5331-5341
    • Garzon, R.1
  • 44
    • 42449141513 scopus 로고    scopus 로고
    • MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia
    • Garzon R, et al. MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia. Blood. 2008;111(6):3183-3189.
    • (2008) Blood. , vol.111 , Issue.6 , pp. 3183-3189
    • Garzon, R.1
  • 45
    • 77950480186 scopus 로고    scopus 로고
    • Sp1/NF?B/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia
    • Liu S, et al. Sp1/NF?B/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia. Cancer Cell. 2010;17(4):333-347.
    • (2010) Cancer Cell. , vol.17 , Issue.4 , pp. 333-347
    • Liu, S.1
  • 46
    • 84872534918 scopus 로고    scopus 로고
    • RNA trafficking by acute myelog-enous leukemia exosomes
    • Huan J, et al. RNA trafficking by acute myelog-enous leukemia exosomes. Cancer Res. 2013;73(2):918-929.
    • (2013) Cancer Res. , vol.73 , Issue.2 , pp. 918-929
    • Huan, J.1
  • 47
    • 84983456248 scopus 로고    scopus 로고
    • Characterization of CLL exosomes reveals a distinct microRNA signature and enhanced secretion by activation of BCR signaling
    • Yeh YY, et al. Characterization of CLL exosomes reveals a distinct microRNA signature and enhanced secretion by activation of BCR signaling. Blood. 2015;125(21):3297-3305.
    • (2015) Blood. , vol.125 , Issue.21 , pp. 3297-3305
    • Yeh, Y.Y.1
  • 48
    • 77955406553 scopus 로고    scopus 로고
    • Tumor-derived microvesicles induce, expand and up-regulate biological activities of human regulatory T cells (Treg)
    • Szajnik M, Czystowska M, Szczepanski MJ, Mandapathil M, Whiteside TL. Tumor-derived microvesicles induce, expand and up-regulate biological activities of human regulatory T cells (Treg). PLoS One. 2010;5(7):e11469.
    • (2010) PLoS One. , vol.5 , Issue.7 , pp. e11469
    • Szajnik, M.1    Czystowska, M.2    Szczepanski, M.J.3    Mandapathil, M.4    Whiteside, T.L.5
  • 49
    • 80052384534 scopus 로고    scopus 로고
    • Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via mem-brane-associated transforming growth factor-ß1
    • Szczepanski MJ, Szajnik M, Welsh A, Whiteside TL, Boyiadzis M. Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via mem-brane-associated transforming growth factor-ß1. Haematologica. 2011;96(9):1302-1309.
    • (2011) Haematologica. , vol.96 , Issue.9 , pp. 1302-1309
    • Szczepanski, M.J.1    Szajnik, M.2    Welsh, A.3    Whiteside, T.L.4    Boyiadzis, M.5
  • 50
    • 84873149964 scopus 로고    scopus 로고
    • Immune modulation of T-cell and NK (natural killer) cell activities by TEXs (tumour-derived exosomes)
    • Whiteside TL. Immune modulation of T-cell and NK (natural killer) cell activities by TEXs (tumour-derived exosomes). Biochem Soc Trans. 2013;41(1):245-251.
    • (2013) Biochem Soc Trans. , vol.41 , Issue.1 , pp. 245-251
    • Whiteside, T.L.1
  • 52
    • 84898725160 scopus 로고    scopus 로고
    • Clonal tracking of rhesus macaque hematopoiesis highlights a distinct lineage origin for natural killer cells
    • Wu C, et al. Clonal tracking of rhesus macaque hematopoiesis highlights a distinct lineage origin for natural killer cells. Cell Stem Cell. 2014;14(4):486-499.
    • (2014) Cell Stem Cell. , vol.14 , Issue.4 , pp. 486-499
    • Wu, C.1
  • 53
    • 60549117539 scopus 로고    scopus 로고
    • IL-15 trans-presentation promotes human NK cell development and differentiation in vivo
    • Huntington ND, et al. IL-15 trans-presentation promotes human NK cell development and differentiation in vivo. J Exp Med. 2009;206(1):25-34.
    • (2009) J Exp Med. , vol.206 , Issue.1 , pp. 25-34
    • Huntington, N.D.1
  • 54
    • 78149439385 scopus 로고    scopus 로고
    • CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset
    • Lopez-Vergès S, et al. CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset. Blood. 2010;116(19):3865-3874.
    • (2010) Blood. , vol.116 , Issue.19 , pp. 3865-3874
    • Lopez-Vergès, S.1
  • 55
    • 34247150402 scopus 로고    scopus 로고
    • CD56brightCD16-kill-er Ig-like receptor-NK cells display longer telomeres and acquire features of CD56dim NK cells upon activation
    • Romagnani C, et al. CD56brightCD16-kill-er Ig-like receptor-NK cells display longer telomeres and acquire features of CD56dim NK cells upon activation. J Immunol. 2007;178(8):4947-4955.
    • (2007) J Immunol. , vol.178 , Issue.8 , pp. 4947-4955
    • Romagnani, C.1
  • 56
    • 75649122988 scopus 로고    scopus 로고
    • CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets
    • Yu J, et al. CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets. Blood. 2010;115(2):274-281.
    • (2010) Blood. , vol.115 , Issue.2 , pp. 274-281
    • Yu, J.1
  • 57
    • 0037606040 scopus 로고    scopus 로고
    • CD56bright natural killer cells are present in human lymph nodes and are activated by T cell-derived IL-2: A potential new link between adaptive and innate immunity
    • Fehniger TA, et al. CD56bright natural killer cells are present in human lymph nodes and are activated by T cell-derived IL-2: a potential new link between adaptive and innate immunity. Blood. 2003;101(8):3052-3057.
    • (2003) Blood. , vol.101 , Issue.8 , pp. 3052-3057
    • Fehniger, T.A.1
  • 58
    • 84864565435 scopus 로고    scopus 로고
    • Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias
    • Zorko NA, et al. Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias. Blood. 2012;120(5):1130-1136.
    • (2012) Blood. , vol.120 , Issue.5 , pp. 1130-1136
    • Zorko, N.A.1
  • 59
    • 84930802235 scopus 로고    scopus 로고
    • Disruption of miR-29 leads to aberrant differentiation of smooth muscle cells selectively associated with distal lung vascula-ture
    • Cushing L, et al. Disruption of miR-29 leads to aberrant differentiation of smooth muscle cells selectively associated with distal lung vascula-ture. PLoS Genet. 2015;11(5):e1005238.
    • (2015) PLoS Genet. , vol.11 , Issue.5 , pp. e1005238
    • Cushing, L.1
  • 60
    • 84879147532 scopus 로고    scopus 로고
    • Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells
    • Trotta R, et al. Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells. Blood. 2013;121(16):3126-3134.
    • (2013) Blood. , vol.121 , Issue.16 , pp. 3126-3134
    • Trotta, R.1
  • 61
    • 84859864322 scopus 로고    scopus 로고
    • MiR-155 regulates IFN-? Production in natural killer cells
    • Trotta R, et al. miR-155 regulates IFN-? production in natural killer cells. Blood. 2012;119(15):3478-3485.
    • (2012) Blood. , vol.119 , Issue.15 , pp. 3478-3485
    • Trotta, R.1
  • 62
    • 84925036069 scopus 로고    scopus 로고
    • Transcription factor Foxo1 is a negative regulator of natural killer cell maturation and function
    • Deng Y, et al. Transcription factor Foxo1 is a negative regulator of natural killer cell maturation and function. Immunity. 2015;42(3):457-470.
    • (2015) Immunity. , vol.42 , Issue.3 , pp. 457-470
    • Deng, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.