메뉴 건너뛰기




Volumn 2, Issue 5, 2014, Pages

Paracellular route is the major urate transport pathway across the blood-placental barrier

Author keywords

Paracellular; Placenta; Syncytiotrophoblast; Urate transporter; Uric acid

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; ESTRONE SULFATE; GLUCOSE TRANSPORTER; GLUCOSE TRANSPORTER 9; HYPOXANTHINE; ORGANIC ANION TRANSPORTER 10; ORGANIC ANION TRANSPORTER 4; UNCLASSIFIED DRUG;

EID: 85002687746     PISSN: None     EISSN: 2051817X     Source Type: Journal    
DOI: 10.14814/phy2.12013     Document Type: Article
Times cited : (13)

References (39)
  • 1
    • 33846837206 scopus 로고    scopus 로고
    • New insights into renal transport of urate
    • Anzai, N., Y. Kanai, and H. Endou. 2007. New insights into renal transport of urate. Curr. Opin. Rheumatol. 19:151-157.
    • (2007) Curr. Opin. Rheumatol , vol.19 , pp. 151-157
    • Anzai, N.1    Kanai, Y.2    Endou, H.3
  • 2
    • 55249096942 scopus 로고    scopus 로고
    • Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans
    • Anzai, N., K. Ichida, P. Jutabha, T. Kimura, E. Babu, C. J. Jin, et al. 2008. Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans. J. Biol. Chem. 283:26834-26838.
    • (2008) J. Biol. Chem , vol.283 , pp. 26834-26838
    • Anzai, N.1    Ichida, K.2    Jutabha, P.3    Kimura, T.4    Babu, E.5    Jin, C.J.6
  • 3
    • 84858276787 scopus 로고    scopus 로고
    • Recent advances in renal urate transport: Characterization of candidate transporters indicated by genome-wide association studies
    • Anzai, N., P. Jutabha, S. Amonpatumrat-Takahashi, and H. Sakurai. 2012. Recent advances in renal urate transport: characterization of candidate transporters indicated by genome-wide association studies. Clin. Exp. Nephrol. 16:89-95.
    • (2012) Clin. Exp. Nephrol , vol.16 , pp. 89-95
    • Anzai, N.1    Jutabha, P.2    Amonpatumrat-Takahashi, S.3    Sakurai, H.4
  • 4
    • 1942437498 scopus 로고    scopus 로고
    • Identification and characterization of human glucose transporter-like protein-9 (GLUT9)-Alternative splicing alters trafficking
    • Augustin, R., M. O. Carayannopoulos, L. O. Dowd, J. E. Phay, J. F. Moley, and K. H. Moley. 2004. Identification and characterization of human glucose transporter-like protein-9 (GLUT9)-Alternative splicing alters trafficking. J. Biol. Chem. 279:16229-16236.
    • (2004) J. Biol. Chem , vol.279 , pp. 16229-16236
    • Augustin, R.1    Carayannopoulos, M.O.2    Dowd, L.O.3    Phay, J.E.4    Moley, J.F.5    Moley, K.H.6
  • 5
    • 47749112096 scopus 로고    scopus 로고
    • Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13)
    • Bahn, A., Y. Hagos, S. Reuter, D. Balen, H. Brzica, W. Krick, et al. 2008. Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13). J. Biol. Chem. 283:16332-16341.
    • (2008) J. Biol. Chem , vol.283 , pp. 16332-16341
    • Bahn, A.1    Hagos, Y.2    Reuter, S.3    Balen, D.4    Brzica, H.5    Krick, W.6
  • 6
    • 0242290366 scopus 로고    scopus 로고
    • Human organic anion transporter 3 (HOAT3) can operate as an exchanger and mediate secretory urate flux
    • Bakhiya, A., A. Bahn, G. Burckhardt, and N. Wolff. 2003. Human organic anion transporter 3 (hOAT3) can operate as an exchanger and mediate secretory urate flux. Cell. Physiol. Biochem. 13:249-256.
    • (2003) Cell. Physiol. Biochem , vol.13 , pp. 249-256
    • Bakhiya, A.1    Bahn, A.2    Burckhardt, G.3    Wolff, N.4
  • 7
    • 79952508984 scopus 로고    scopus 로고
    • Asymmetric syncytial expression of GLUT9 splice variants in human term placenta and alterations in diabetic pregnancies
    • Bibee, K. P., N. P. Illsley, and K. H. Moley. 2011. Asymmetric syncytial expression of GLUT9 splice variants in human term placenta and alterations in diabetic pregnancies. Reprod. Sci. 18:20-27.
    • (2011) Reprod. Sci , vol.18 , pp. 20-27
    • Bibee, K.P.1    Illsley, N.P.2    Moley, K.H.3
  • 8
    • 84867866650 scopus 로고    scopus 로고
    • Renal transport of uric acid: Evolving concepts and uncertainties
    • Bobulescu, I. A., and O. W. Moe. 2012. Renal transport of uric acid: evolving concepts and uncertainties. Adv. Chronic Kidney Dis. 19:358-371.
    • (2012) Adv. Chronic Kidney Dis , vol.19 , pp. 358-371
    • Bobulescu, I.A.1    Moe, O.W.2
  • 9
    • 0013950256 scopus 로고
    • Serum uric acid levels in normal pregnancy with observations on the renal excretion of urate in pregnancy
    • Boyle, J. A., S. Campbell, A. M. Duncan, W. R. Greig, and W. W. Buchanan. 1966. Serum uric acid levels in normal pregnancy with observations on the renal excretion of urate in pregnancy. J. Clin. Pathol. 19:501-503.
    • (1966) J. Clin. Pathol , vol.19 , pp. 501-503
    • Boyle, J.A.1    Campbell, S.2    Duncan, A.M.3    Greig, W.R.4    Buchanan, W.W.5
  • 10
    • 0028055641 scopus 로고
    • Transport of PAH, urate, TEA, and fluid by isolated perfused and nonperfused avian renal proximal tubules
    • Brokl, O. H., E. J. Braun, and W. H. Dantzler. 1994. Transport of PAH, urate, TEA, and fluid by isolated perfused and nonperfused avian renal proximal tubules. Am. J. Physiol. 266:R1085-R1094.
    • (1994) Am. J. Physiol , vol.266 , pp. R1085-R1094
    • Brokl, O.H.1    Braun, E.J.2    Dantzler, W.H.3
  • 11
    • 0000518648 scopus 로고    scopus 로고
    • Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta
    • Cha, S. H., T. Sekine, H. Kusuhara, E. Yu, J. Y. Kim, D. K. Kim, et al. 2000. Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. J. Biol. Chem. 275:4507-4512.
    • (2000) J. Biol. Chem , vol.275 , pp. 4507-4512
    • Cha, S.H.1    Sekine, T.2    Kusuhara, H.3    Yu, E.4    Kim, J.Y.5    Kim, D.K.6
  • 14
    • 0037161834 scopus 로고    scopus 로고
    • Molecular identification of a renal urate anion exchanger that regulates blood urate levels
    • Enomoto, A., H. Kimura, A. Chairoungdua, Y. Shigeta, P. Jutabha, S. H. Cha, et al. 2002. Molecular identification of a renal urate anion exchanger that regulates blood urate levels. Nature 417:447-452.
    • (2002) Nature , vol.417 , pp. 447-452
    • Enomoto, A.1    Kimura, H.2    Chairoungdua, A.3    Shigeta, Y.4    Jutabha, P.5    Cha, S.H.6
  • 15
    • 0021809877 scopus 로고
    • Plasma renin activity, blood uric acid and plasma volume in pregnancy-induced hypertension
    • Fievet, P., L. Pleskov, I. Desailly, A. Carayon, J. F. de Fremont, B. Coevoet, et al. 1985. Plasma renin activity, blood uric acid and plasma volume in pregnancy-induced hypertension. Nephron 40:429-432.
    • (1985) Nephron , vol.40 , pp. 429-432
    • Fievet, P.1    Pleskov, L.2    Desailly, I.3    Carayon, A.4    De Fremont, J.F.5    Coevoet, B.6
  • 17
    • 0035166355 scopus 로고    scopus 로고
    • Etiology of third-trimester maternal hyperuricemia in nonpreeclamptic twin gestations
    • Fischer, R. L. M., L. S. M. Weisberg, and M. L. P. Hediger. 2001. Etiology of third-trimester maternal hyperuricemia in nonpreeclamptic twin gestations. Obstet. Gynecol. 97:62-65.
    • (2001) Obstet. Gynecol , vol.97 , pp. 62-65
    • Fischer, R.L.M.1    Weisberg, L.S.M.2    Hediger, M.L.P.3
  • 18
    • 33846692496 scopus 로고    scopus 로고
    • Human renal organic anion transporter 4 operates as an asymmetric urate transporter
    • Hagos, Y., D. Stein, B. Ugele, G. Burckhardt, and A. Bahn. 2007. Human renal organic anion transporter 4 operates as an asymmetric urate transporter. J. Am. Soc. Nephrol. 18:430-439.
    • (2007) J. Am. Soc. Nephrol , vol.18 , pp. 430-439
    • Hagos, Y.1    Stein, D.2    Ugele, B.3    Burckhardt, G.4    Bahn, A.5
  • 19
    • 0346734163 scopus 로고    scopus 로고
    • Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion
    • Ichida, K., M. Hosoyamada, I. Hisatome, A. Enomoto, M. Hikita, H. Endou, et al. 2004. Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion. J. Am. Soc. Nephrol. 15:164-173.
    • (2004) J. Am. Soc. Nephrol , vol.15 , pp. 164-173
    • Ichida, K.1    Hosoyamada, M.2    Hisatome, I.3    Enomoto, A.4    Hikita, M.5    Endou, H.6
  • 20
    • 78049387680 scopus 로고    scopus 로고
    • Human sodium phosphate transporter 4 (HNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate
    • Jutabha, P., N. Anzai, K. Kitamura, A. Taniguchi, S. Kaneko, K. Yan, et al. 2010. Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate. J. Biol. Chem. 285:35123-35132.
    • (2010) J. Biol. Chem , vol.285 , pp. 35123-35132
    • Jutabha, P.1    Anzai, N.2    Kitamura, K.3    Taniguchi, A.4    Kaneko, S.5    Yan, K.6
  • 21
    • 0028105873 scopus 로고
    • Levels of erythrocyte malonyldialdehyde, vitamin E, reduced glutathione, G6PD activity & plasma urate in patients of pregnancy induced hypertension
    • Kabi, B. C., N. Goel, Y. N. Rao, R. Tripathy, A. Tempe, and A. S. Thakur. 1994. Levels of erythrocyte malonyldialdehyde, vitamin E, reduced glutathione, G6PD activity and plasma urate in patients of pregnancy induced hypertension. Indian J. Med. Res. 100:23-25.
    • (1994) Indian J. Med. Res , vol.100 , pp. 23-25
    • Kabi, B.C.1    Goel, N.2    Rao, Y.N.3    Tripathy, R.4    Tempe, A.5    Thakur, A.S.6
  • 22
    • 84896963895 scopus 로고    scopus 로고
    • Expression of SLC2A9 isoforms in the kidney and their localization in polarized epithelial cells
    • Kimura, T., M. Takahashi, K. Yan, and H. Sakurai. 2014. Expression of SLC2A9 isoforms in the kidney and their localization in polarized epithelial cells. PLoS One 9: e84996.
    • (2014) Plos One , vol.9
    • Kimura, T.1    Takahashi, M.2    Yan, K.3    Sakurai, H.4
  • 23
    • 85004889178 scopus 로고
    • The uric acid content of the blood of new-borns
    • Kingsbury, F. B., and J. P. Sedgwick. 1917. The uric acid content of the blood of new-borns. J. Biol. Chem. 31: 261-268.
    • (1917) J. Biol. Chem , vol.31 , pp. 261-268
    • Kingsbury, F.B.1    Sedgwick, J.P.2
  • 24
    • 0021314623 scopus 로고
    • Risk grouping of 113 patients with hypertensive disorders during pregnancy, with respect to serum urate, proteinuria and time of onset of hypertension
    • Liedholm, H., S. Montan, and A. Aberg. 1984. Risk grouping of 113 patients with hypertensive disorders during pregnancy, with respect to serum urate, proteinuria and time of onset of hypertension. Acta Obstet. Gynecol. Scand. Suppl. 118:43-48.
    • (1984) Cta Obstet. Gynecol. Scand. Suppl , vol.118 , pp. 43-48
    • Liedholm, H.1    Montan, S.2    Aberg, A.3
  • 25
    • 84860836541 scopus 로고    scopus 로고
    • Regulation of uric acid excretion by the kidney
    • Lipkowitz, M. S. 2012. Regulation of uric acid excretion by the kidney. Curr. Rheumatol. Rep. 14:179-188.
    • (2012) Curr. Rheumatol. Rep , vol.14 , pp. 179-188
    • Lipkowitz, M.S.1
  • 27
    • 84860876716 scopus 로고    scopus 로고
    • Intestinal ischemia-reperfusion increases efflux for uric acid via paracellular route in the intestine, but decreases that via transcellular route mediated by BCRP
    • Ogura, J., K. Kuwayama, A. Takaya, Y. Terada, T. Tsujimoto, T. Koizumi, et al. 2012. Intestinal ischemia-reperfusion increases efflux for uric acid via paracellular route in the intestine, but decreases that via transcellular route mediated by BCRP. J. Pharm. Pharm. Sci. 15:295-304.
    • (2012) J. Pharm. Pharm. Sci , vol.15 , pp. 295-304
    • Ogura, J.1    Kuwayama, K.2    Takaya, A.3    Terada, Y.4    Tsujimoto, T.5    Koizumi, T.6
  • 28
    • 0019568177 scopus 로고
    • Determination of the apparent transport constants for urate absorption in the rat proximal tubule
    • Sansom, S. C., H. O. Senekjian, T. F. Knight, H. Babino, D. Steplock, and E. J. Weinman. 1981. Determination of the apparent transport constants for urate absorption in the rat proximal tubule. Am. J. Physiol. 240:F406-F410.
    • (1981) Am. J. Physiol , vol.240 , pp. F406-F410
    • Sansom, S.C.1    Senekjian, H.O.2    Knight, T.F.3    Babino, H.4    Steplock, D.5    Weinman, E.J.6
  • 29
    • 0030855487 scopus 로고    scopus 로고
    • Expression cloning and characterization of a novel multispecific organic anion transporter
    • Sekine, T., N. Watanabe, M. Hosoyamada, Y. Kanai, and H. Endou. 1997. Expression cloning and characterization of a novel multispecific organic anion transporter. J. Biol. Chem. 272:18526-18529.
    • (1997) J. Biol. Chem , vol.272 , pp. 18526-18529
    • Sekine, T.1    Watanabe, N.2    Hosoyamada, M.3    Kanai, Y.4    Endou, H.5
  • 30
    • 0001901705 scopus 로고
    • The uric acid content of maternal and fetal blood
    • Slemons, J. M., and L. J. Bogert. 1917. The uric acid content of maternal and fetal blood. J. Biol. Chem. 32:63-69.
    • (1917) J. Biol. Chem , vol.32 , pp. 63-69
    • Slemons, J.M.1    Bogert, L.J.2
  • 31
    • 4344667232 scopus 로고    scopus 로고
    • Maternal plasma hypoxanthine levels in nonpreeclamptic twin pregnancies
    • Suzuki, S., and Y. Yoneyama. 2004. Maternal plasma hypoxanthine levels in nonpreeclamptic twin pregnancies. Tohoku J. Exp. Med. 203:349-352.
    • (2004) Tohoku J. Exp. Med , vol.203 , pp. 349-352
    • Suzuki, S.1    Yoneyama, Y.2
  • 32
    • 0034595094 scopus 로고    scopus 로고
    • P-aminohippuric acid transport at renal apical membrane mediated by human inorganic phosphate transporter NPT1
    • Uchino, H., I. Tamai, K. Yamashita, Y. Minemoto, Y. Sai, H. Yabuuchi, et al. 2000. p-aminohippuric acid transport at renal apical membrane mediated by human inorganic phosphate transporter NPT1. Biochem. Biophys. Res. Commun. 270:254-259.
    • (2000) Biochem. Biophys. Res. Commun , vol.270 , pp. 254-259
    • Uchino, H.1    Tamai, I.2    Yamashita, K.3    Minemoto, Y.4    Sai, Y.5    Yabuuchi, H.6
  • 33
    • 12144257103 scopus 로고    scopus 로고
    • Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites
    • Van Aubel, R. A., P. H. Smeets, J. J. van den Heuvel, and F. G. Russel. 2005. Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites. Am. J. Physiol. Renal. Physiol. 288:F327-F333.
    • (2005) Am. J. Physiol. Renal. Physiol , vol.288 , pp. F327-F333
    • Van Aubel, R.A.1    Smeets, P.H.2    Van Den Heuvel, J.J.3    Russel, F.G.4
  • 34
    • 0023759443 scopus 로고
    • Uric acid levels: A useful index of the severity of preeclampsia and perinatal prognosis
    • Voto, L. S., R. Illia, H. A. Darbon-Grosso, F. U. Imaz, and M. Margulies. 1988. Uric acid levels: a useful index of the severity of preeclampsia and perinatal prognosis. J. Perinat. Med. 16:123-126.
    • (1988) J. Perinat. Med , vol.16 , pp. 123-126
    • Voto, L.S.1    Illia, R.2    Darbon-Grosso, H.A.3    Imaz, F.U.4    Margulies, M.5
  • 35
    • 0033188484 scopus 로고    scopus 로고
    • Estimation of plasma uric acid in pregnancy induced hypertension (PIH). Is the test still relevant
    • Wakwe, V. C., and O. O. Abudu. 1999. Estimation of plasma uric acid in pregnancy induced hypertension (PIH). Is the test still relevant? Afr. J. Med. Med. Sci. 28:155-158.
    • (1999) Afr. J. Med. Med. Sci , vol.28 , pp. 155-158
    • Wakwe, V.C.1    Abudu, O.O.2
  • 36
    • 0020535886 scopus 로고
    • Effect of anion exchange inhibitors and para-aminohippurate on the transport of urate in the rat proximal tubule
    • Weinman, E. J., S. C. Sansom, S. Bennett, and A. M. Kahn. 1983. Effect of anion exchange inhibitors and para-aminohippurate on the transport of urate in the rat proximal tubule. Kidney Int. 23:832-837.
    • (1983) Kidney Int , vol.23 , pp. 832-837
    • Weinman, E.J.1    Sansom, S.C.2    Bennett, S.3    Kahn, A.M.4
  • 39
    • 0037455066 scopus 로고    scopus 로고
    • Vaginal submucosal dendritic cells, but not Langerhans cells, induce protective Th1 responses to herpes simplex virus-2
    • Zhao, X., E. Deak, K. Soderberg, M. Linehan, D. Spezzano, J. Zhu, et al. 2003. Vaginal submucosal dendritic cells, but not Langerhans cells, induce protective Th1 responses to herpes simplex virus-2. J. Exp. Med. 197:153-162.
    • (2003) J. Exp. Med , vol.197 , pp. 153-162
    • Zhao, X.1    Deak, E.2    Soderberg, K.3    Linehan, M.4    Spezzano, D.5    Zhu, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.