Viral and bacterial co-infection in severe pneumonia triggers innate immune responses and specifically enhances IP-10: A translational study

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Hoffmann, Jonathan ^a   MacHado, Daniela ^a   Terrier, Olivier ^b   Pouzol, Stephane ^a   Messaoudi, Mélina ^a   Basualdo, Wilma ^c   Espínola, Emilio E ^d   Guillen, Rosa M ^d   Rosa Calatrava, Manuel ^b   Picot, Valentina ^a   Bénet, Thomas ^e   Endtz, Hubert ^a   Russomando, Graciela ^d   Paranhos Baccalà, Glaúcia ^a  

^a CENTRE INTERNATIONAL DE RECHERCHE EN INFECTIOLOGIE   (France)

^b INSERM   (France)

^c Laboratorio Central de Salud Pública   (Paraguay)

^d UNIVERSIDAD NACIONAL DE ASUNCIÓN   (Paraguay)

^e EDOUARD HERRIOT HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL10 PROTEIN, HUMAN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; MESSENGER RNA; MICRORNA; SOCS6 PROTEIN, HUMAN; SUPPRESSOR OF CYTOKINE SIGNALING;

ADULT; AGED; BACTERIAL INFECTION; BIOLOGICAL MODEL; FEMALE; GENE EXPRESSION PROFILING; GENETICS; HUMAN; IMMUNOLOGY; INFANT; INFLUENZA A VIRUS (H1N1); INNATE IMMUNITY; MACROPHAGE; MALE; METABOLISM; MICROBIOLOGY; MIDDLE AGED; MIXED INFECTION; NUCLEOTIDE SEQUENCE; PNEUMONIA; STREPTOCOCCUS PNEUMONIAE; TRANSLATIONAL RESEARCH; VIROLOGY; VIRUS INFECTION; YOUNG ADULT;

ADULT; AGED; BACTERIAL INFECTIONS; BASE SEQUENCE; CHEMOKINE CXCL10; COINFECTION; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IMMUNITY, INNATE; INFANT; INFLUENZA A VIRUS, H1N1 SUBTYPE; MACROPHAGES; MALE; MICRORNAS; MIDDLE AGED; MODELS, BIOLOGICAL; PNEUMONIA; RNA, MESSENGER; STREPTOCOCCUS PNEUMONIAE; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANSLATIONAL MEDICAL RESEARCH; VIRUS DISEASES; YOUNG ADULT;

EID: 85002158079     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep38532     Document Type: Article

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