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Volumn 311, Issue , 2017, Pages 36-45

Hepatic expansion of virus-specific CD8+BTLA+ T cells with regulatory properties in chronic hepatitis B virus infection

Author keywords

B and T lymphocyte attenuator; Chronic virus infection; Hepatitis B virus; Regulatory CD8+ T cells

Indexed keywords

B AND LYMPHOCYTE ATTENUATOR; CD27 ANTIGEN; CD45RA ANTIGEN; CYTOKINE; GAMMA INTERFERON; HLA A24 ANTIGEN; INTERLEUKIN 10; PROGRAMMED DEATH 1 RECEPTOR; TETRAMER; UNCLASSIFIED DRUG; VIRUS DNA; BTLA PROTEIN, MOUSE; IMMUNOGLOBULIN RECEPTOR;

EID: 85002061897     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2016.10.002     Document Type: Article
Times cited : (26)

References (35)
  • 1
    • 14944375587 scopus 로고    scopus 로고
    • Immunology of hepatitis B virus and hepatitis C virus infection
    • [1] Rehermann, B., Nascimbeni, M., Immunology of hepatitis B virus and hepatitis C virus infection. Nat. Rev. Immunol. 5 (2005), 215–229.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 215-229
    • Rehermann, B.1    Nascimbeni, M.2
  • 2
    • 0038461904 scopus 로고    scopus 로고
    • Kinetics of the immune response during HBV and HCV infection
    • [2] Bertoletti, A., Ferrari, C., Kinetics of the immune response during HBV and HCV infection. Hepatology 38 (2003), 4–13.
    • (2003) Hepatology , vol.38 , pp. 4-13
    • Bertoletti, A.1    Ferrari, C.2
  • 3
    • 79956077563 scopus 로고    scopus 로고
    • T cell exhaustion
    • [3] Wherry, E.J., T cell exhaustion. Nat. Immunol. 12 (2011), 492–499.
    • (2011) Nat. Immunol. , vol.12 , pp. 492-499
    • Wherry, E.J.1
  • 4
    • 36349000276 scopus 로고    scopus 로고
    • The phenotype of hepatitis B virus-specific T cells differ in the liver and blood in chronic hepatitis B virus infection
    • [4] Chang, J.J., Thompson, A.J., Visvanathan, K., et al. The phenotype of hepatitis B virus-specific T cells differ in the liver and blood in chronic hepatitis B virus infection. Hepatology 46 (2007), 1332–1340.
    • (2007) Hepatology , vol.46 , pp. 1332-1340
    • Chang, J.J.1    Thompson, A.J.2    Visvanathan, K.3
  • 5
    • 44649166448 scopus 로고    scopus 로고
    • Dynamic programmed death 1 expression by virus-specific CD8 T cells correlates with the outcome of acute hepatitis B
    • 1949, e1-3
    • [5] Zhang, Z., Zhang, J.Y., Wherry, E.J., et al. Dynamic programmed death 1 expression by virus-specific CD8 T cells correlates with the outcome of acute hepatitis B. Gastroenterology 134 (2008), 1938–1949 1949, e1-3.
    • (2008) Gastroenterology , vol.134 , pp. 1938-1949
    • Zhang, Z.1    Zhang, J.Y.2    Wherry, E.J.3
  • 6
    • 34247117935 scopus 로고    scopus 로고
    • Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection
    • [6] Boni, C., Fisicaro, P., Valdatta, C., et al. Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection. J. Virol. 81 (2007), 4215–4225.
    • (2007) J. Virol. , vol.81 , pp. 4215-4225
    • Boni, C.1    Fisicaro, P.2    Valdatta, C.3
  • 7
    • 84868159278 scopus 로고    scopus 로고
    • Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection
    • [7] Nebbia, G., Peppa, D., Schurich, A., et al. Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection. PLoS One, 7, 2012, e47648.
    • (2012) PLoS One , vol.7 , pp. e47648
    • Nebbia, G.1    Peppa, D.2    Schurich, A.3
  • 8
    • 77958486229 scopus 로고    scopus 로고
    • Regulatory T cells in HBV and HCV liver diseases: implication of regulatory T lymphocytes in the control of immuneresponse
    • [8] Miroux, C., Vausselin, T., Delhem, N., Regulatory T cells in HBV and HCV liver diseases: implication of regulatory T lymphocytes in the control of immuneresponse. Expert Opin. Biol. Ther. 10 (2010), 1563–1572.
    • (2010) Expert Opin. Biol. Ther. , vol.10 , pp. 1563-1572
    • Miroux, C.1    Vausselin, T.2    Delhem, N.3
  • 9
    • 0036597371 scopus 로고    scopus 로고
    • CD4+ CD25+ suppressor T cells: more questions than answers
    • [9] Shevach, E.M., CD4+ CD25+ suppressor T cells: more questions than answers. Nat. Rev. Immunol. 2 (2002), 389–400.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 10
    • 2142702915 scopus 로고    scopus 로고
    • Hepatic expansion of a virus-specific regulatory CD8(+) T cell population in chronic hepatitis C virus infection
    • [10] Accapezzato, D., Francavilla, V., Paroli, M., et al. Hepatic expansion of a virus-specific regulatory CD8(+) T cell population in chronic hepatitis C virus infection. J. Clin. Invest. 113 (2004), 963–972.
    • (2004) J. Clin. Invest. , vol.113 , pp. 963-972
    • Accapezzato, D.1    Francavilla, V.2    Paroli, M.3
  • 11
    • 84881635553 scopus 로고    scopus 로고
    • Role of regulatory T cells during virus infection
    • [11] Veiga-Parga, T., Sehrawat, S., Rouse, B.T., Role of regulatory T cells during virus infection. Immunol. Rev. 255 (2013), 182–196.
    • (2013) Immunol. Rev. , vol.255 , pp. 182-196
    • Veiga-Parga, T.1    Sehrawat, S.2    Rouse, B.T.3
  • 12
    • 84864770681 scopus 로고    scopus 로고
    • Regulatory T cells are the most important determinant factor of hepatitis B infection prognosis: a systematic review and meta-analysis
    • [12] Aalaei-Andabili, S.H., Alavian, S.M., Regulatory T cells are the most important determinant factor of hepatitis B infection prognosis: a systematic review and meta-analysis. Vaccine 30 (2012), 5595–5602.
    • (2012) Vaccine , vol.30 , pp. 5595-5602
    • Aalaei-Andabili, S.H.1    Alavian, S.M.2
  • 13
    • 84880119204 scopus 로고    scopus 로고
    • Cutting edge: prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells
    • [13] Youngblood, B., Noto, A., Porichis, F., et al. Cutting edge: prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells. J. Immunol. 191 (2013), 540–544.
    • (2013) J. Immunol. , vol.191 , pp. 540-544
    • Youngblood, B.1    Noto, A.2    Porichis, F.3
  • 14
    • 84875538870 scopus 로고    scopus 로고
    • Re-evaluation of PD-1 expression by T cells as a marker for immune exhaustion during SIV infection
    • [14] Hong, J.J., Amancha, P.K., Rogers, K., et al. Re-evaluation of PD-1 expression by T cells as a marker for immune exhaustion during SIV infection. PLoS One, 8, 2013, e60186.
    • (2013) PLoS One , vol.8 , pp. e60186
    • Hong, J.J.1    Amancha, P.K.2    Rogers, K.3
  • 15
    • 0028235641 scopus 로고
    • Classification of chronic hepatitis: diagnosis, grading and staging
    • [15] Desmet, V.J., Gerber, M., Hoofnagle, J.H., et al. Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 19 (1994), 1513–1520.
    • (1994) Hepatology , vol.19 , pp. 1513-1520
    • Desmet, V.J.1    Gerber, M.2    Hoofnagle, J.H.3
  • 16
    • 75149117314 scopus 로고    scopus 로고
    • Antiviral intrahepatic T-cell responses can be restored by blocking programmed death-1 pathway in chronic hepatitis B
    • 693, e1–4
    • [16] Fisicaro, P., Valdatta, C., Massari, M., et al. Antiviral intrahepatic T-cell responses can be restored by blocking programmed death-1 pathway in chronic hepatitis B. Gastroenterology 138 (2010), 682–693 693, e1–4.
    • (2010) Gastroenterology , vol.138 , pp. 682-693
    • Fisicaro, P.1    Valdatta, C.2    Massari, M.3
  • 17
    • 84891490960 scopus 로고    scopus 로고
    • B and T lymphocyte attenuator is highly expressed on intrahepatic T cells during chronic HBV infection and regulates their function
    • [17] Cai, G., Nie, X., Li, L., et al. B and T lymphocyte attenuator is highly expressed on intrahepatic T cells during chronic HBV infection and regulates their function. J. Gastroenterol. 48 (2013), 1362–1372.
    • (2013) J. Gastroenterol. , vol.48 , pp. 1362-1372
    • Cai, G.1    Nie, X.2    Li, L.3
  • 18
    • 78649912279 scopus 로고    scopus 로고
    • B and T lymphocyte attenuator is highly expressed on CMV-specific T cells during infection and regulates their function
    • [18] Serriari, N.E., Gondois-Rey, F., Guillaume, Y., et al. B and T lymphocyte attenuator is highly expressed on CMV-specific T cells during infection and regulates their function. J. Immunol. 185 (2010), 3140–3148.
    • (2010) J. Immunol. , vol.185 , pp. 3140-3148
    • Serriari, N.E.1    Gondois-Rey, F.2    Guillaume, Y.3
  • 19
    • 84884677993 scopus 로고    scopus 로고
    • A novel nanoparticle containing MOG peptide with BTLA induces T cell tolerance and prevents multiple sclerosis
    • [19] Yuan, B., Zhao, L., Fu, F., et al. A novel nanoparticle containing MOG peptide with BTLA induces T cell tolerance and prevents multiple sclerosis. Mol. Immunol. 57 (2013), 93–99.
    • (2013) Mol. Immunol. , vol.57 , pp. 93-99
    • Yuan, B.1    Zhao, L.2    Fu, F.3
  • 20
    • 70849103215 scopus 로고    scopus 로고
    • Amelioration of myocarditis by HVEM-overexpressing dendritic cells through induction of IL-10-producing cells
    • [20] Cai, G., Wang, H., Qin, Q., et al. Amelioration of myocarditis by HVEM-overexpressing dendritic cells through induction of IL-10-producing cells. Cardiovasc. Res. 84 (2009), 425–433.
    • (2009) Cardiovasc. Res. , vol.84 , pp. 425-433
    • Cai, G.1    Wang, H.2    Qin, Q.3
  • 21
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • [21] Maloy, K.J., Powrie, F., Regulatory T cells in the control of immune pathology. Nat. Immunol. 2 (2001), 816–822.
    • (2001) Nat. Immunol. , vol.2 , pp. 816-822
    • Maloy, K.J.1    Powrie, F.2
  • 22
    • 0034716925 scopus 로고    scopus 로고
    • Regulatory T cells: key controllers of immunologic self-tolerance
    • [22] Sakaguchi, S., Regulatory T cells: key controllers of immunologic self-tolerance. Cell 101 (2000), 455–458.
    • (2000) Cell , vol.101 , pp. 455-458
    • Sakaguchi, S.1
  • 23
    • 79953709110 scopus 로고    scopus 로고
    • Regulation of inflammation, autoimmunity, and infection immunity by HVEM-BTLA signaling
    • [23] Shui, J.W., Steinberg, M.W., Kronenberg, M., Regulation of inflammation, autoimmunity, and infection immunity by HVEM-BTLA signaling. J. Leukoc. Biol. 89 (2011), 517–523.
    • (2011) J. Leukoc. Biol. , vol.89 , pp. 517-523
    • Shui, J.W.1    Steinberg, M.W.2    Kronenberg, M.3
  • 24
    • 77952317248 scopus 로고    scopus 로고
    • Slow down and survive: Enigmatic immunoregulation by BTLA and HVEM
    • [24] Murphy, T.L., Murphy, K.M., Slow down and survive: Enigmatic immunoregulation by BTLA and HVEM. Annu. Rev. Immunol. 28 (2010), 389–411.
    • (2010) Annu. Rev. Immunol. , vol.28 , pp. 389-411
    • Murphy, T.L.1    Murphy, K.M.2
  • 25
    • 33645220927 scopus 로고    scopus 로고
    • Expression of the interleukin-7 receptor alpha chain (CD127) on virus-specific CD8+ T cells identifies functionally and phenotypically defined memory T cells during acute resolving hepatitis B virus infection
    • [25] Boettler, T., Panther, E., Bengsch, B., et al. Expression of the interleukin-7 receptor alpha chain (CD127) on virus-specific CD8+ T cells identifies functionally and phenotypically defined memory T cells during acute resolving hepatitis B virus infection. J. Virol. 80 (2006), 3532–3540.
    • (2006) J. Virol. , vol.80 , pp. 3532-3540
    • Boettler, T.1    Panther, E.2    Bengsch, B.3
  • 26
    • 0037340417 scopus 로고    scopus 로고
    • Lineage relationship and protective immunity of memory CD8 T cell subsets
    • [26] Wherry, E.J., Teichgräber, V., Becker, T.C., et al. Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat. Immunol. 4 (2003), 225–234.
    • (2003) Nat. Immunol. , vol.4 , pp. 225-234
    • Wherry, E.J.1    Teichgräber, V.2    Becker, T.C.3
  • 27
    • 0037385715 scopus 로고    scopus 로고
    • T cell fitness determined by signal strength
    • [27] Gett, A.V., Sallusto, F., Lanzavecchia, A., et al. T cell fitness determined by signal strength. Nat. Immunol. 4 (2003), 355–360.
    • (2003) Nat. Immunol. , vol.4 , pp. 355-360
    • Gett, A.V.1    Sallusto, F.2    Lanzavecchia, A.3
  • 28
    • 84863393290 scopus 로고    scopus 로고
    • CD8(+) T cells specific for tumor antigens can be rendered dysfunctional by the tumor microenvironment through upregulation of the inhibitory receptors BTLA and PD-1
    • [28] Fourcade, J., Sun, Z., Pagliano, O., et al. CD8(+) T cells specific for tumor antigens can be rendered dysfunctional by the tumor microenvironment through upregulation of the inhibitory receptors BTLA and PD-1. Cancer Res. 72 (2012), 887–896.
    • (2012) Cancer Res. , vol.72 , pp. 887-896
    • Fourcade, J.1    Sun, Z.2    Pagliano, O.3
  • 29
    • 84866176745 scopus 로고    scopus 로고
    • CD160 and PD-1 co-expression on HIV-specific CD8 T cells defines a subset with advanced dysfunction
    • [29] Peretz, Y., He, Z., Shi, Y., et al. CD160 and PD-1 co-expression on HIV-specific CD8 T cells defines a subset with advanced dysfunction. PLoS Pathog., 8, 2012, e1002840.
    • (2012) PLoS Pathog. , vol.8 , pp. e1002840
    • Peretz, Y.1    He, Z.2    Shi, Y.3
  • 30
    • 79957661532 scopus 로고    scopus 로고
    • Bim-mediated apoptosis and PD-1/PD-L1 pathway impair reactivity of PD1(+)/CD127(−) HCV-specific CD8(+) cells targeting the virus in chronic hepatitis C virus infection
    • [30] Larrubia, J.R., Benito-Martínez, S., Miquel, J., et al. Bim-mediated apoptosis and PD-1/PD-L1 pathway impair reactivity of PD1(+)/CD127(−) HCV-specific CD8(+) cells targeting the virus in chronic hepatitis C virus infection. Cell. Immunol. 269 (2011), 104–114.
    • (2011) Cell. Immunol. , vol.269 , pp. 104-114
    • Larrubia, J.R.1    Benito-Martínez, S.2    Miquel, J.3
  • 31
    • 65649139622 scopus 로고    scopus 로고
    • PD-L1 negatively regulates CD4+CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV
    • [31] Franceschini, D., Paroli, M., Francavilla, V., et al. PD-L1 negatively regulates CD4+CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV. J. Clin. Invest. 119 (2009), 551–564.
    • (2009) J. Clin. Invest. , vol.119 , pp. 551-564
    • Franceschini, D.1    Paroli, M.2    Francavilla, V.3
  • 32
    • 84887822666 scopus 로고    scopus 로고
    • Recurrence of another hepatitis B virus escape mutant comes back in a patient infected with HIV and low CD4+ count
    • [32] Milazzo, L., Ebranati, E., Cattaneo, D., et al. Recurrence of another hepatitis B virus escape mutant comes back in a patient infected with HIV and low CD4+ count. J. Med. Virol. 86 (2014), 97–101.
    • (2014) J. Med. Virol. , vol.86 , pp. 97-101
    • Milazzo, L.1    Ebranati, E.2    Cattaneo, D.3
  • 33
    • 77957346775 scopus 로고    scopus 로고
    • Molecular genetics of HBV infection
    • [33] Locarnini, S., Zoulim, F., Molecular genetics of HBV infection. Antivir. Ther. 15:Suppl. 3 (2010), 3–14.
    • (2010) Antivir. Ther. , vol.15 , pp. 3-14
    • Locarnini, S.1    Zoulim, F.2
  • 34
    • 65449117568 scopus 로고    scopus 로고
    • Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells
    • [34] Wu, J., Meng, Z., Jiang, M., et al. Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells. Hepatology 49 (2009), 1132–1140.
    • (2009) Hepatology , vol.49 , pp. 1132-1140
    • Wu, J.1    Meng, Z.2    Jiang, M.3
  • 35
    • 77955496554 scopus 로고    scopus 로고
    • The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein
    • [35] Wei, C., Ni, C., Song, T., et al. The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein. J. Immunol. 185 (2010), 1158–1168.
    • (2010) J. Immunol. , vol.185 , pp. 1158-1168
    • Wei, C.1    Ni, C.2    Song, T.3


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