Mutational landscape in children with myelodysplastic syndromes is distinct from adults: Specific somatic drivers and novel germline variants

Leukemia

Volumn 31, Issue 3, 2017, Pages 759-762

  Pastor, V ^a   Hirabayashi, S ^a,h   Karow, A ^b,h,i   Wehrle, J ^c,d   Kozyra, E J ^a   Nienhold, R ^b   Ruzaike, G ^a   Lebrecht, D ^a   Yoshimi, A ^a   Niewisch, M ^a   Ripperger, T ^d,e   Gohring G ^d,e   Baumann, I ^e   Schwarz, S ^f,g   Strahm, B ^a   Flotho, C ^a,d   Skoda, R C ^b   Niemeyer, C M ^a,d   Wlodarski, M W ^a,d  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

^c UNIVERSITY OF FREIBURG   (Germany)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^e HANNOVER MEDICAL SCHOOL   (Germany)

^f Department of Pathology   (Germany)

^g UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^h ST LUKE'S INTERNATIONAL HOSPITAL   (Japan)

ⁱ UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR RUNX1;

ADOLESCENT; CHILD; CHILDHOOD CANCER; CLINICAL ARTICLE; COHORT ANALYSIS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETIC VARIABILITY; GERMLINE MUTATION; GRANULOCYTE; HUMAN; LETTER; MALE; MONOSOMY 7; MUTATIONAL ANALYSIS; MYELODYSPLASTIC SYNDROME; NEXT GENERATION SEQUENCING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SANGER SEQUENCING; SOMATIC MUTATION; ADULT; DNA MUTATIONAL ANALYSIS; GENETIC DATABASE; GENETICS; MUTATION; PRESCHOOL CHILD; PROCEDURES;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; DATABASES, GENETIC; DNA MUTATIONAL ANALYSIS; FEMALE; GERM-LINE MUTATION; HUMANS; MALE; MUTATION; MYELODYSPLASTIC SYNDROMES;

EID: 85001610207     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2016.342     Document Type: Letter

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