-
1
-
-
84929439166
-
A 4-Drug combination (viekira pak) for hepatitis C
-
Abramowicz, M., Zuccotti, G., Pflomm, J.M., A 4-Drug combination (viekira pak) for hepatitis C. Jama-J Am. Med. Assoc. 313 (2015), 1857–1858.
-
(2015)
Jama-J Am. Med. Assoc.
, vol.313
, pp. 1857-1858
-
-
Abramowicz, M.1
Zuccotti, G.2
Pflomm, J.M.3
-
2
-
-
15944425764
-
Sensitive determination of clarithromycin in human plasma by high-performance liquid chromatography with spectrophotometric detection
-
Amini, H., Ahmadiani, A., Sensitive determination of clarithromycin in human plasma by high-performance liquid chromatography with spectrophotometric detection. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 817 (2005), 193–197.
-
(2005)
J. Chromatogr. B Anal. Technol. Biomed. Life Sci.
, vol.817
, pp. 193-197
-
-
Amini, H.1
Ahmadiani, A.2
-
3
-
-
77949569493
-
Antibiotic resistance and its cost: is it possible to reverse resistance?
-
Andersson, D.I., Hughes, D., Antibiotic resistance and its cost: is it possible to reverse resistance?. Nat. Rev. Microbiol. 8 (2010), 260–271.
-
(2010)
Nat. Rev. Microbiol.
, vol.8
, pp. 260-271
-
-
Andersson, D.I.1
Hughes, D.2
-
4
-
-
80052851832
-
Ebola virus entry requires the cholesterol transporter Niemann-Pick C1
-
340–U115
-
Carette, J.E., Raaben, M., Wong, A.C., Herbert, A.S., Obernosterer, G., Mulherkar, N., Kuehne, A.I., Kranzusch, P.J., Griffin, A.M., Ruthel, G., Dal Cin, P., Dye, J.M., Whelan, S.P., Chandran, K., Brummelkamp, T.R., Ebola virus entry requires the cholesterol transporter Niemann-Pick C1. Nature, 477, 2011 340–U115.
-
(2011)
Nature
, vol.477
-
-
Carette, J.E.1
Raaben, M.2
Wong, A.C.3
Herbert, A.S.4
Obernosterer, G.5
Mulherkar, N.6
Kuehne, A.I.7
Kranzusch, P.J.8
Griffin, A.M.9
Ruthel, G.10
Dal Cin, P.11
Dye, J.M.12
Whelan, S.P.13
Chandran, K.14
Brummelkamp, T.R.15
-
5
-
-
19144365133
-
Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection
-
Chandran, K., Sullivan, N.J., Felbor, U., Whelan, S.P., Cunningham, J.M., Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection. Science 308 (2005), 1643–1645.
-
(2005)
Science
, vol.308
, pp. 1643-1645
-
-
Chandran, K.1
Sullivan, N.J.2
Felbor, U.3
Whelan, S.P.4
Cunningham, J.M.5
-
6
-
-
80052868218
-
Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection
-
344–U122
-
Cote, M., Misasi, J., Ren, T., Bruchez, A., Lee, K., Filone, C.M., Hensley, L., Li, Q., Ory, D., Chandran, K., Cunningham, J., Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection. Nature, 477, 2011 344–U122.
-
(2011)
Nature
, vol.477
-
-
Cote, M.1
Misasi, J.2
Ren, T.3
Bruchez, A.4
Lee, K.5
Filone, C.M.6
Hensley, L.7
Li, Q.8
Ory, D.9
Chandran, K.10
Cunningham, J.11
-
7
-
-
0033815396
-
Pharmacokinetics of (deaminohydroxy)toremifene in humans: a new, selective estrogen-receptor modulator
-
DeGregorio, M.W., Wurz, G.T., Taras, T.L., Erkkola, R.U., Halonen, K.H., Huupponen, R.K., Pharmacokinetics of (deaminohydroxy)toremifene in humans: a new, selective estrogen-receptor modulator. Eur. J. Clin. Pharmacol. 56 (2000), 469–475.
-
(2000)
Eur. J. Clin. Pharmacol.
, vol.56
, pp. 469-475
-
-
DeGregorio, M.W.1
Wurz, G.T.2
Taras, T.L.3
Erkkola, R.U.4
Halonen, K.H.5
Huupponen, R.K.6
-
8
-
-
84857693882
-
Productive replication of Ebola virus is regulated by the c-abl1 tyrosine kinase
-
Garcia, M., Cooper, A., Shi, W., Bornmann, W., Carrion, R., Kalman, D., Nabel, G.J., Productive replication of Ebola virus is regulated by the c-abl1 tyrosine kinase. Sci. Transl. Med., 4, 2012.
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Garcia, M.1
Cooper, A.2
Shi, W.3
Bornmann, W.4
Carrion, R.5
Kalman, D.6
Nabel, G.J.7
-
9
-
-
84936947069
-
Niemann-pick C1 Is Essential for Ebolavirus Replication and Pathogenesis in Vivo
-
Mbio 6
-
Herbert, A.S., Davidson, C., Kuehne, A.I., Bakken, R., Braigen, S.Z., Gunn, K.E., Whelan, S.P., Brummelkamp, T.R., Twenhafel, N.A., Chandran, K., Walkley, S.U., Dye, J.M., Niemann-pick C1 Is Essential for Ebolavirus Replication and Pathogenesis in Vivo. 2015 Mbio 6.
-
(2015)
-
-
Herbert, A.S.1
Davidson, C.2
Kuehne, A.I.3
Bakken, R.4
Braigen, S.Z.5
Gunn, K.E.6
Whelan, S.P.7
Brummelkamp, T.R.8
Twenhafel, N.A.9
Chandran, K.10
Walkley, S.U.11
Dye, J.M.12
-
10
-
-
0029095483
-
Time to hit HIV, early and hard
-
Ho, D.D., Time to hit HIV, early and hard. N. Engl. J. Med. 333 (1995), 450–451.
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 450-451
-
-
Ho, D.D.1
-
11
-
-
84937631791
-
Emerging intracellular receptors for hemorrhagic fever viruses
-
Jae, L.T., Brummelkamp, T.R., Emerging intracellular receptors for hemorrhagic fever viruses. Trends Microbiol. 23 (2015), 392–400.
-
(2015)
Trends Microbiol.
, vol.23
, pp. 392-400
-
-
Jae, L.T.1
Brummelkamp, T.R.2
-
12
-
-
84880544466
-
FDA-approved selective estrogen receptor modulators inhibit Ebola virus infection
-
190ra179
-
Johansen, L.M., Brannan, J.M., Delos, S.E., Shoemaker, C.J., Stossel, A., Lear, C., Hoffstrom, B.G., Dewald, L.E., Schornberg, K.L., Scully, C., Lehar, J., Hensley, L.E., White, J.M., Olinger, G.G., FDA-approved selective estrogen receptor modulators inhibit Ebola virus infection. Sci. Transl. Med., 5, 2013 190ra179.
-
(2013)
Sci. Transl. Med.
, vol.5
-
-
Johansen, L.M.1
Brannan, J.M.2
Delos, S.E.3
Shoemaker, C.J.4
Stossel, A.5
Lear, C.6
Hoffstrom, B.G.7
Dewald, L.E.8
Schornberg, K.L.9
Scully, C.10
Lehar, J.11
Hensley, L.E.12
White, J.M.13
Olinger, G.G.14
-
13
-
-
0028345515
-
Pharmacokinetics of mefloquine alone or in combination with artesunate
-
Karbwang, J., Na Bangchang, K., Thanavibul, A., Back, D.J., Bunnag, D., Harinasuta, T., Pharmacokinetics of mefloquine alone or in combination with artesunate. Bull. World Health Organ 72 (1994), 83–87.
-
(1994)
Bull. World Health Organ
, vol.72
, pp. 83-87
-
-
Karbwang, J.1
Na Bangchang, K.2
Thanavibul, A.3
Back, D.J.4
Bunnag, D.5
Harinasuta, T.6
-
14
-
-
84921918086
-
Pharmacokinetics and safety study of posaconazole intravenous solution administered peripherally to healthy subjects
-
Kersemaekers, W.M., van Iersel, T., Nassander, U., O'Mara, E., Waskin, H., Caceres, M., van Iersel, M.L., Pharmacokinetics and safety study of posaconazole intravenous solution administered peripherally to healthy subjects. Antimicrob. Agents Chemother. 59 (2015), 1246–1251.
-
(2015)
Antimicrob. Agents Chemother.
, vol.59
, pp. 1246-1251
-
-
Kersemaekers, W.M.1
van Iersel, T.2
Nassander, U.3
O'Mara, E.4
Waskin, H.5
Caceres, M.6
van Iersel, M.L.7
-
15
-
-
84924964870
-
Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs
-
Kouznetsova, J., Sun, W., Martinez-Romero, C., Tawa, G., Shinn, P., Chen, C.Z., Schimmer, A., Sanderson, P., McKew, J.C., Zheng, W., Garcia-Sastre, A., Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs. Emerg. Microbes Infect., 3, 2014, e84.
-
(2014)
Emerg. Microbes Infect.
, vol.3
, pp. e84
-
-
Kouznetsova, J.1
Sun, W.2
Martinez-Romero, C.3
Tawa, G.4
Shinn, P.5
Chen, C.Z.6
Schimmer, A.7
Sanderson, P.8
McKew, J.C.9
Zheng, W.10
Garcia-Sastre, A.11
-
16
-
-
84875965830
-
A systematic screen of FDA-approved drugs for inhibitors of biological threat agents
-
Madrid, P.B., Chopra, S., Manger, I.D., Gilfillan, L., Keepers, T.R., Shurtleff, A.C., Green, C.E., Iyer, L.V., Dilks, H.H., Davey, R.A., Kolokoltsov, A.A., Carrion, R. Jr., Patterson, J.L., Bavari, S., Panchal, R.G., Warren, T.K., Wells, J.B., Moos, W.H., Burke, R.L., Tanga, M.J., A systematic screen of FDA-approved drugs for inhibitors of biological threat agents. PLoS One, 8, 2013, e60579.
-
(2013)
PLoS One
, vol.8
, pp. e60579
-
-
Madrid, P.B.1
Chopra, S.2
Manger, I.D.3
Gilfillan, L.4
Keepers, T.R.5
Shurtleff, A.C.6
Green, C.E.7
Iyer, L.V.8
Dilks, H.H.9
Davey, R.A.10
Kolokoltsov, A.A.11
Carrion, R.12
Patterson, J.L.13
Bavari, S.14
Panchal, R.G.15
Warren, T.K.16
Wells, J.B.17
Moos, W.H.18
Burke, R.L.19
Tanga, M.J.20
more..
-
17
-
-
84863767856
-
Ebolavirus requires acid sphingomyelinase activity and plasma membrane sphingomyelin for infection
-
Miller, M.E., Adhikary, S., Kolokoltsov, A.A., Davey, R.A., Ebolavirus requires acid sphingomyelinase activity and plasma membrane sphingomyelin for infection. J. Virol. 86 (2012), 7473–7483.
-
(2012)
J. Virol.
, vol.86
, pp. 7473-7483
-
-
Miller, M.E.1
Adhikary, S.2
Kolokoltsov, A.A.3
Davey, R.A.4
-
18
-
-
85001072981
-
Helicobacter pylori 23S rRNA gene sequencing for the identification of mutations associated with clarithromycin resistance in FFPE samples
-
373a-373a
-
Mitui, M., Khokhar, S.K., Leos, N.K., Doern, C.D., Park, J.Y., Helicobacter pylori 23S rRNA gene sequencing for the identification of mutations associated with clarithromycin resistance in FFPE samples. Lab. Invest, 93, 2013 373a-373a.
-
(2013)
Lab. Invest
, vol.93
-
-
Mitui, M.1
Khokhar, S.K.2
Leos, N.K.3
Doern, C.D.4
Park, J.Y.5
-
19
-
-
84929486001
-
Ebola virus entry: a curious and complex series of events
-
Moller-Tank, S., Maury, W., Ebola virus entry: a curious and complex series of events. PLoS Pathog., 11, 2015, e1004731.
-
(2015)
PLoS Pathog.
, vol.11
, pp. e1004731
-
-
Moller-Tank, S.1
Maury, W.2
-
20
-
-
4644332720
-
Posaconazole is a potent inhibitor of sterol 14 alpha-demethylation in yeasts and molds
-
Munayyer, H.K., Mann, P.A., Chau, A.S., Yarosh-Tomaine, T., Greene, J.R., Hare, R.S., Heimark, L., Palermo, R.E., Loebenberg, D., McNicholas, P.M., Posaconazole is a potent inhibitor of sterol 14 alpha-demethylation in yeasts and molds. Antimicrob. Agents Chemother. 48 (2004), 3690–3696.
-
(2004)
Antimicrob. Agents Chemother.
, vol.48
, pp. 3690-3696
-
-
Munayyer, H.K.1
Mann, P.A.2
Chau, A.S.3
Yarosh-Tomaine, T.4
Greene, J.R.5
Hare, R.S.6
Heimark, L.7
Palermo, R.E.8
Loebenberg, D.9
McNicholas, P.M.10
-
21
-
-
84867904922
-
Inhibitory effects of pepstatin a and mefloquine on the growth of babesia parasites
-
Munkhjargal, T., AbouLaila, M., Terkawi, M.A., Sivakumar, T., Ichikawa, M., Davaasuren, B., Nyamjargal, T., Yokoyama, N., Igarashi, I., Inhibitory effects of pepstatin a and mefloquine on the growth of babesia parasites. Am. J. Trop. Med. Hyg. 87 (2012), 681–688.
-
(2012)
Am. J. Trop. Med. Hyg.
, vol.87
, pp. 681-688
-
-
Munkhjargal, T.1
AbouLaila, M.2
Terkawi, M.A.3
Sivakumar, T.4
Ichikawa, M.5
Davaasuren, B.6
Nyamjargal, T.7
Yokoyama, N.8
Igarashi, I.9
-
22
-
-
84923815384
-
Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment
-
Sakurai, Y., Kolokoltsov, A.A., Chen, C.C., Tidwell, M.W., Bauta, W.E., Klugbauer, N., Grimm, C., Wahl-Schott, C., Biel, M., Davey, R.A., Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment. Science 347 (2015), 995–998.
-
(2015)
Science
, vol.347
, pp. 995-998
-
-
Sakurai, Y.1
Kolokoltsov, A.A.2
Chen, C.C.3
Tidwell, M.W.4
Bauta, W.E.5
Klugbauer, N.6
Grimm, C.7
Wahl-Schott, C.8
Biel, M.9
Davey, R.A.10
-
23
-
-
78649796783
-
The Position of Mefloquine as a 21(st) Century Malaria Chemoprophylaxis
-
Malaria J 9
-
Schlagenhauf, P., Adamcova, M., Regep, L., Schaerer, M.T., Rhein, H.G., The Position of Mefloquine as a 21(st) Century Malaria Chemoprophylaxis. 2010 Malaria J 9.
-
(2010)
-
-
Schlagenhauf, P.1
Adamcova, M.2
Regep, L.3
Schaerer, M.T.4
Rhein, H.G.5
-
24
-
-
84971672804
-
Drug Combination Therapy Increases Successful Drug Repositioning
-
Drug Discov Today
-
Sun, W., Sanderson, P., Zheng, W., Drug Combination Therapy Increases Successful Drug Repositioning. 2016, Drug Discov Today.
-
(2016)
-
-
Sun, W.1
Sanderson, P.2
Zheng, W.3
-
25
-
-
73049089683
-
An enzymatic virus-like particle assay for sensitive detection of virus entry
-
Tscherne, D.M., Manicassamy, B., Garcia-Sastre, A., An enzymatic virus-like particle assay for sensitive detection of virus entry. J. Virol. Methods 163 (2010), 336–343.
-
(2010)
J. Virol. Methods
, vol.163
, pp. 336-343
-
-
Tscherne, D.M.1
Manicassamy, B.2
Garcia-Sastre, A.3
-
27
-
-
84892696212
-
Toremifene for breast Cancer: a review of 20 Years of data
-
Vogel, C.L., Johnston, M.A., Capers, C., Braccia, D., Toremifene for breast Cancer: a review of 20 Years of data. Clin. Breast Cancer 14 (2014), 1–9.
-
(2014)
Clin. Breast Cancer
, vol.14
, pp. 1-9
-
-
Vogel, C.L.1
Johnston, M.A.2
Capers, C.3
Braccia, D.4
-
28
-
-
33845710284
-
Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: an externally controlled trial
-
Walsh, T.J., Raad, I., Patterson, T.F., Chandrasekar, P., Donowitz, G.R., Graybill, R., Greene, R.E., Hachem, R., Hadley, S., Herbrecht, R., Langston, A., Louie, A., Ribaud, P., Segal, B.H., Stevens, D.A., van Burik, J.A., White, C.S., Corcoran, G., Gogate, J., Krishna, G., Pedicone, L., Hardalo, C., Perfect, J.R., Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: an externally controlled trial. Clin. Infect. Dis. 44 (2007), 2–12.
-
(2007)
Clin. Infect. Dis.
, vol.44
, pp. 2-12
-
-
Walsh, T.J.1
Raad, I.2
Patterson, T.F.3
Chandrasekar, P.4
Donowitz, G.R.5
Graybill, R.6
Greene, R.E.7
Hachem, R.8
Hadley, S.9
Herbrecht, R.10
Langston, A.11
Louie, A.12
Ribaud, P.13
Segal, B.H.14
Stevens, D.A.15
van Burik, J.A.16
White, C.S.17
Corcoran, G.18
Gogate, J.19
Krishna, G.20
Pedicone, L.21
Hardalo, C.22
Perfect, J.R.23
more..
-
29
-
-
78249280753
-
A grid algorithm for high throughput fitting of dose-response curve data
-
Wang, Y., Jadhav, A., Southal, N., Huang, R., Nguyen, D.T., A grid algorithm for high throughput fitting of dose-response curve data. Curr. Chem. Genomics 4 (2010), 57–66.
-
(2010)
Curr. Chem. Genomics
, vol.4
, pp. 57-66
-
-
Wang, Y.1
Jadhav, A.2
Southal, N.3
Huang, R.4
Nguyen, D.T.5
-
30
-
-
84865529940
-
A high-throughput sphingomyelinase assay using natural substrate
-
Xu, M., Liu, K., Southall, N., Marugan, J.J., Remaley, A.T., Zheng, W., A high-throughput sphingomyelinase assay using natural substrate. Anal. Bioanal. Chem. 404 (2012), 407–414.
-
(2012)
Anal. Bioanal. Chem.
, vol.404
, pp. 407-414
-
-
Xu, M.1
Liu, K.2
Southall, N.3
Marugan, J.J.4
Remaley, A.T.5
Zheng, W.6
-
31
-
-
84869223163
-
delta-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders
-
Xu, M., Liu, K., Swaroop, M., Porter, F.D., Sidhu, R., Firnkes, S., Ory, D.S., Marugan, J.J., Xiao, J., Southall, N., Pavan, W.J., Davidson, C., Walkley, S.U., Remaley, A.T., Baxa, U., Sun, W., McKew, J.C., Austin, C.P., Zheng, W., delta-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders. J. Biol. Chem. 287 (2012), 39349–39360.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 39349-39360
-
-
Xu, M.1
Liu, K.2
Swaroop, M.3
Porter, F.D.4
Sidhu, R.5
Firnkes, S.6
Ory, D.S.7
Marugan, J.J.8
Xiao, J.9
Southall, N.10
Pavan, W.J.11
Davidson, C.12
Walkley, S.U.13
Remaley, A.T.14
Baxa, U.15
Sun, W.16
McKew, J.C.17
Austin, C.P.18
Zheng, W.19
-
32
-
-
84978437369
-
Toremifene interacts with and destabilizes the Ebola virus glycoprotein
-
Zhao, Y., Ren, J., Harlos, K., Jones, D.M., Zeltina, A., Bowden, T.A., Padilla-Parra, S., Fry, E.E., Stuart, D.I., Toremifene interacts with and destabilizes the Ebola virus glycoprotein. Nature 535 (2016), 169–172.
-
(2016)
Nature
, vol.535
, pp. 169-172
-
-
Zhao, Y.1
Ren, J.2
Harlos, K.3
Jones, D.M.4
Zeltina, A.5
Bowden, T.A.6
Padilla-Parra, S.7
Fry, E.E.8
Stuart, D.I.9
|