메뉴 건너뛰기




Volumn 83, Issue 3, 2017, Pages 444-454

Efficacy of bisphosphonate as an adjunct to nonsurgical periodontal therapy in the management of periodontal disease: a systematic review

Author keywords

Bisphosphonates; periodontal disease; scaling and root planning; systematic review

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; NERIDRONIC ACID;

EID: 85000360797     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/bcp.13147     Document Type: Review
Times cited : (55)

References (44)
  • 2
    • 0040991018 scopus 로고
    • Effect of rough surfaces upon gingival tissues
    • Waerhaug J. Effect of rough surfaces upon gingival tissues. J Dent Res 1956; 35: 323–325.
    • (1956) J Dent Res , vol.35 , pp. 323-325
    • Waerhaug, J.1
  • 3
    • 0036583007 scopus 로고    scopus 로고
    • Clinical significance of non-surgical periodontal therapy: an evidence-based perspective of scaling and root planing
    • Cobb CM. Clinical significance of non-surgical periodontal therapy: an evidence-based perspective of scaling and root planing. J Clin Periodontol 2002; 29: 22–32.
    • (2002) J Clin Periodontol , vol.29 , pp. 22-32
    • Cobb, C.M.1
  • 4
    • 84960483862 scopus 로고    scopus 로고
    • Role of antimicrobial photodynamic therapy in the treatment of aggressive periodontitis: a systematic review
    • Vohra F, Akram Z, Safii SH, Vaithilingam RD, Ghanem A, Sergis K, et al. Role of antimicrobial photodynamic therapy in the treatment of aggressive periodontitis: a systematic review. Photodiagnosis Photodyn Ther 2015; 13: 139–147.
    • (2015) Photodiagnosis Photodyn Ther , vol.13 , pp. 139-147
    • Vohra, F.1    Akram, Z.2    Safii, S.H.3    Vaithilingam, R.D.4    Ghanem, A.5    Sergis, K.6
  • 5
    • 84964200227 scopus 로고    scopus 로고
    • Bactericidal efficacy of photodynamic therapy against periodontal pathogens in periodontal disease: a systematic review
    • Akram Z, Al-Shareef SA, Daood U, Asiri FY, Shah AH, AlQahtani MA, et al. Bactericidal efficacy of photodynamic therapy against periodontal pathogens in periodontal disease: a systematic review. Photomed Laser Surg 2016; 34: 137–149.
    • (2016) Photomed Laser Surg , vol.34 , pp. 137-149
    • Akram, Z.1    Al-Shareef, S.A.2    Daood, U.3    Asiri, F.Y.4    Shah, A.H.5    AlQahtani, M.A.6
  • 6
    • 84992126230 scopus 로고    scopus 로고
    • Effect of photodynamic therapy and laser alone as adjunct to scaling and root planing on gingival crevicular fluid inflammatory proteins in periodontal disease: a systematic review
    • Akram Z, Abduljabbar T, Sauro S, Daood U. Effect of photodynamic therapy and laser alone as adjunct to scaling and root planing on gingival crevicular fluid inflammatory proteins in periodontal disease: a systematic review. Photodiagnosis Photodyn Ther 2016. doi:10.1016/j.pdpdt.2016.09.004.
    • (2016) Photodiagnosis Photodyn Ther
    • Akram, Z.1    Abduljabbar, T.2    Sauro, S.3    Daood, U.4
  • 7
    • 84989201965 scopus 로고    scopus 로고
    • Role of lasers as an adjunct to scaling and root planing in patients with type 2 diabetes mellitus: a systematic review
    • Abduljabbar T, Javed F, Shah A, Samer MS, Vohra F, Akram Z. Role of lasers as an adjunct to scaling and root planing in patients with type 2 diabetes mellitus: a systematic review. Lasers Med Sci 2016. doi:10.1007/s10103-016-2086-5.
    • (2016) Lasers Med Sci
    • Abduljabbar, T.1    Javed, F.2    Shah, A.3    Samer, M.S.4    Vohra, F.5    Akram, Z.6
  • 8
    • 84962168804 scopus 로고    scopus 로고
    • Antibiotics/antimicrobials: systemic and local administration in the therapy of mild to moderately advanced periodontitis
    • Jepsen K, Jepsen S. Antibiotics/antimicrobials: systemic and local administration in the therapy of mild to moderately advanced periodontitis. Periodontol 2000 2016; 71: 82–112.
    • (2016) Periodontol 2000 , vol.71 , pp. 82-112
    • Jepsen, K.1    Jepsen, S.2
  • 9
    • 43049109229 scopus 로고    scopus 로고
    • Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy
    • Russell R, Watts N, Ebetino F, Rogers M. Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy. Osteoporos Int 2008; 19: 733–759.
    • (2008) Osteoporos Int , vol.19 , pp. 733-759
    • Russell, R.1    Watts, N.2    Ebetino, F.3    Rogers, M.4
  • 11
    • 33845912677 scopus 로고    scopus 로고
    • Therapy insight: the risks and benefits of bisphosphonates for the treatment of tumor-induced bone disease
    • Dunstan CR, Felsenberg D, Seibel MJ. Therapy insight: the risks and benefits of bisphosphonates for the treatment of tumor-induced bone disease. Nat Clin Pract Oncol 2007; 4: 42–55.
    • (2007) Nat Clin Pract Oncol , vol.4 , pp. 42-55
    • Dunstan, C.R.1    Felsenberg, D.2    Seibel, M.J.3
  • 12
    • 23944461952 scopus 로고    scopus 로고
    • Mechanism of action of bisphosphonates
    • Reszka AA, Rodan GA. Mechanism of action of bisphosphonates. Curr Osteoporos Rep 2003; 1: 45–52.
    • (2003) Curr Osteoporos Rep , vol.1 , pp. 45-52
    • Reszka, A.A.1    Rodan, G.A.2
  • 13
    • 84865963753 scopus 로고    scopus 로고
    • Effects of low-dose doxycycline and bisphosphonate clodronate on alveolar bone loss and gingival levels of matrix metalloproteinase-9 and interleukin-1β in rats with diabetes: a histomorphometric and immunohistochemical study
    • Özdemir SP, Kurtis B, Tüter G, Bozkurt S, Gültekin SE, Sengüven B, et al. Effects of low-dose doxycycline and bisphosphonate clodronate on alveolar bone loss and gingival levels of matrix metalloproteinase-9 and interleukin-1β in rats with diabetes: a histomorphometric and immunohistochemical study. J Periodontol 2012; 83: 1172–1182.
    • (2012) J Periodontol , vol.83 , pp. 1172-1182
    • Özdemir, S.P.1    Kurtis, B.2    Tüter, G.3    Bozkurt, S.4    Gültekin, S.E.5    Sengüven, B.6
  • 14
    • 84906791340 scopus 로고    scopus 로고
    • Matrix metalloproteinases and periodontal diseases
    • Sapna G, Gokul S, Bagri-Manjrekar K. Matrix metalloproteinases and periodontal diseases. Oral Dis 2014; 20: 538–550.
    • (2014) Oral Dis , vol.20 , pp. 538-550
    • Sapna, G.1    Gokul, S.2    Bagri-Manjrekar, K.3
  • 15
    • 49449106328 scopus 로고    scopus 로고
    • Host-response therapeutics for periodontal diseases
    • Giannobile WV. Host-response therapeutics for periodontal diseases. J Periodontol 2008; 79: 1592–1600.
    • (2008) J Periodontol , vol.79 , pp. 1592-1600
    • Giannobile, W.V.1
  • 16
    • 84874633511 scopus 로고    scopus 로고
    • 1% alendronate gel as local drug delivery in the treatment of class II furcation defects: a randomized controlled clinical trial
    • Pradeep A, Kumari M, Rao NS, Naik SB. 1% alendronate gel as local drug delivery in the treatment of class II furcation defects: a randomized controlled clinical trial. J Periodontol 2013; 84: 307–315.
    • (2013) J Periodontol , vol.84 , pp. 307-315
    • Pradeep, A.1    Kumari, M.2    Rao, N.S.3    Naik, S.B.4
  • 17
    • 84863393245 scopus 로고    scopus 로고
    • Clinical efficacy of 1% alendronate gel as a local drug delivery system in the treatment of chronic periodontitis: a randomized, controlled clinical trial
    • Sharma A, Pradeep A. Clinical efficacy of 1% alendronate gel as a local drug delivery system in the treatment of chronic periodontitis: a randomized, controlled clinical trial. J Periodontol 2012; 83: 11–18.
    • (2012) J Periodontol , vol.83 , pp. 11-18
    • Sharma, A.1    Pradeep, A.2
  • 18
    • 64949139040 scopus 로고    scopus 로고
    • Lack of short-term adjunctive effect of systemic neridronate in non-surgical periodontal therapy of advanced generalized chronic periodontitis: an open label-randomized clinical trial
    • Graziani F, Cei S, Guerrero A, La Ferla F, Vano M, Tonetti M, et al. Lack of short-term adjunctive effect of systemic neridronate in non-surgical periodontal therapy of advanced generalized chronic periodontitis: an open label-randomized clinical trial. J Clin Periodontol 2009; 36: 419–427.
    • (2009) J Clin Periodontol , vol.36 , pp. 419-427
    • Graziani, F.1    Cei, S.2    Guerrero, A.3    La Ferla, F.4    Vano, M.5    Tonetti, M.6
  • 19
    • 69149107165 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
    • Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 2009; 151: 264–269.
    • (2009) Ann Intern Med , vol.151 , pp. 264-269
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 20
    • 77953611072 scopus 로고    scopus 로고
    • CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials
    • Moher D, Hopewell S, Schulz KF, Montori V, Gøtzsche PC, Devereaux PJ, et al. CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. J Clin Epidemiol 2010; 63: e1–37.
    • (2010) J Clin Epidemiol , vol.63 , pp. e1-37
    • Moher, D.1    Hopewell, S.2    Schulz, K.F.3    Montori, V.4    Gøtzsche, P.C.5    Devereaux, P.J.6
  • 24
    • 84856002448 scopus 로고    scopus 로고
    • Clinical efficacy of 1% alendronate gel in adjunct to mechanotherapy in the treatment of aggressive periodontitis: a randomized controlled clinical trial
    • Sharma A, Pradeep A. Clinical efficacy of 1% alendronate gel in adjunct to mechanotherapy in the treatment of aggressive periodontitis: a randomized controlled clinical trial. J Periodontol 2012; 83: 19–26.
    • (2012) J Periodontol , vol.83 , pp. 19-26
    • Sharma, A.1    Pradeep, A.2
  • 25
    • 84867169921 scopus 로고    scopus 로고
    • Local drug delivery of alendronate gel for the treatment of patients with chronic periodontitis with diabetes mellitus: a double-masked controlled clinical trial
    • Pradeep A, Sharma A, Rao NS, Bajaj P, Naik SB, Kumari M. Local drug delivery of alendronate gel for the treatment of patients with chronic periodontitis with diabetes mellitus: a double-masked controlled clinical trial. J Periodontol 2012; 83: 1322–1328.
    • (2012) J Periodontol , vol.83 , pp. 1322-1328
    • Pradeep, A.1    Sharma, A.2    Rao, N.S.3    Bajaj, P.4    Naik, S.B.5    Kumari, M.6
  • 26
    • 23044488738 scopus 로고    scopus 로고
    • Bisphosphonate therapy improves the outcome of conventional periodontal treatment: results of a 12-month, randomized, placebo-controlled study
    • Lane N, Armitage GC, Loomer P, Hsieh S, Majumdar S, Wang HY, et al. Bisphosphonate therapy improves the outcome of conventional periodontal treatment: results of a 12-month, randomized, placebo-controlled study. J Periodontol 2005; 76: 1113–1122.
    • (2005) J Periodontol , vol.76 , pp. 1113-1122
    • Lane, N.1    Armitage, G.C.2    Loomer, P.3    Hsieh, S.4    Majumdar, S.5    Wang, H.Y.6
  • 27
    • 13844311046 scopus 로고    scopus 로고
    • Effect of alendronate on periodontal disease in postmenopausal women: a randomized placebo-controlled trial
    • Rocha ML, Malacara JM, Sánchez-Marin FJ, de la Torre CJV, Fajardo ME. Effect of alendronate on periodontal disease in postmenopausal women: a randomized placebo-controlled trial. J Periodontol 2004; 75: 1579–1585.
    • (2004) J Periodontol , vol.75 , pp. 1579-1585
    • Rocha, M.L.1    Malacara, J.M.2    Sánchez-Marin, F.J.3    de la Torre, C.J.V.4    Fajardo, M.E.5
  • 28
    • 0034966432 scopus 로고    scopus 로고
    • Clinical and radiological improvement of periodontal disease in patients with type 2 diabetes mellitus treated with alendronate: a randomized, placebo-controlled trial
    • Rocha M, Nava LE, de la Torre CV, Sánchez-Marín F, Garay-Sevilla ME, Malacara JM. Clinical and radiological improvement of periodontal disease in patients with type 2 diabetes mellitus treated with alendronate: a randomized, placebo-controlled trial. J Periodontol 2001; 72: 204–209.
    • (2001) J Periodontol , vol.72 , pp. 204-209
    • Rocha, M.1    Nava, L.E.2    de la Torre, C.V.3    Sánchez-Marín, F.4    Garay-Sevilla, M.E.5    Malacara, J.M.6
  • 29
    • 0024406012 scopus 로고
    • Inhibition of osteoclast-like cell formation by bisphosphonates in long-term cultures of human bone marrow
    • Hughes D, MacDonald B, Russell R, Gowen M. Inhibition of osteoclast-like cell formation by bisphosphonates in long-term cultures of human bone marrow. J Clin Investig 1989; 83: 1930–1935.
    • (1989) J Clin Investig , vol.83 , pp. 1930-1935
    • Hughes, D.1    MacDonald, B.2    Russell, R.3    Gowen, M.4
  • 30
    • 0029934545 scopus 로고    scopus 로고
    • Bisphosphonates induce osteoblasts to secrete an inhibitor of osteoclast-mediated resorption
    • Vitte C, Fleisch H, Guenther HL. Bisphosphonates induce osteoblasts to secrete an inhibitor of osteoclast-mediated resorption. Endocrinol 1996; 137: 2324–2333.
    • (1996) Endocrinol , vol.137 , pp. 2324-2333
    • Vitte, C.1    Fleisch, H.2    Guenther, H.L.3
  • 31
    • 27344453813 scopus 로고    scopus 로고
    • Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment
    • Marx RE, Sawatari Y, Fortin M, Broumand V. Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment. J Oral Maxillofac Surg 2005; 63: 1567–1575.
    • (2005) J Oral Maxillofac Surg , vol.63 , pp. 1567-1575
    • Marx, R.E.1    Sawatari, Y.2    Fortin, M.3    Broumand, V.4
  • 32
    • 29144519913 scopus 로고    scopus 로고
    • Osteonecrosis of the jaws in patients with a history of receiving bisphosphonate therapy: strategies for prevention and early recognition
    • Melo MD, Obeid G. Osteonecrosis of the jaws in patients with a history of receiving bisphosphonate therapy: strategies for prevention and early recognition. J Am Dent Assoc 2005; 136: 1675–1681.
    • (2005) J Am Dent Assoc , vol.136 , pp. 1675-1681
    • Melo, M.D.1    Obeid, G.2
  • 33
    • 50649114676 scopus 로고    scopus 로고
    • Osteonecrosis of the maxilla and mandible in patients with advanced cancer treated with bisphosphonate therapy
    • Estilo CL, Van Poznak CH, Wiliams T, Bohle GC, Lwin PT, Zhou Q, et al. Osteonecrosis of the maxilla and mandible in patients with advanced cancer treated with bisphosphonate therapy. Oncologist 2008; 13: 911–920.
    • (2008) Oncologist , vol.13 , pp. 911-920
    • Estilo, C.L.1    Van Poznak, C.H.2    Wiliams, T.3    Bohle, G.C.4    Lwin, P.T.5    Zhou, Q.6
  • 34
    • 84873411988 scopus 로고    scopus 로고
    • A systematic review on the effects of local antimicrobials as adjuncts to subgingival debridement, compared with subgingival debridement alone, in the treatment of chronic periodontitis
    • Matesanz-Pérez P, García-Gargallo M, Figuero E, Bascones-Martínez A, Sanz M, Herrera D. A systematic review on the effects of local antimicrobials as adjuncts to subgingival debridement, compared with subgingival debridement alone, in the treatment of chronic periodontitis. J Clin Periodontol 2013; 40: 227–241.
    • (2013) J Clin Periodontol , vol.40 , pp. 227-241
    • Matesanz-Pérez, P.1    García-Gargallo, M.2    Figuero, E.3    Bascones-Martínez, A.4    Sanz, M.5    Herrera, D.6
  • 35
    • 84877093537 scopus 로고    scopus 로고
    • Single or repeated antimicrobial photodynamic therapy as adjunct to ultrasonic debridement in residual periodontal pockets: clinical, microbiological, and local biological effects
    • Campanile VSM, Giannopoulou C, Campanile G, Cancela JA, Mombelli A. Single or repeated antimicrobial photodynamic therapy as adjunct to ultrasonic debridement in residual periodontal pockets: clinical, microbiological, and local biological effects. Lasers Med Sci 2015; 30: 27–34.
    • (2015) Lasers Med Sci , vol.30 , pp. 27-34
    • Campanile, V.S.M.1    Giannopoulou, C.2    Campanile, G.3    Cancela, J.A.4    Mombelli, A.5
  • 36
    • 84861820208 scopus 로고    scopus 로고
    • Periodontal regeneration with enamel matrix derivative in reconstructive periodontal therapy: a systematic review
    • Koop R, Merheb J, Quirynen M. Periodontal regeneration with enamel matrix derivative in reconstructive periodontal therapy: a systematic review. J Periodontol 2012; 83: 707–720.
    • (2012) J Periodontol , vol.83 , pp. 707-720
    • Koop, R.1    Merheb, J.2    Quirynen, M.3
  • 37
    • 33646950003 scopus 로고    scopus 로고
    • Local drug delivery in the treatment of periodontal diseases: assessing the clinical significance of the results
    • Greenstein G. Local drug delivery in the treatment of periodontal diseases: assessing the clinical significance of the results. J Periodontol 2006; 77: 565–578.
    • (2006) J Periodontol , vol.77 , pp. 565-578
    • Greenstein, G.1
  • 39
    • 84884963680 scopus 로고    scopus 로고
    • Effects of ageing, prolonged estrogen deficiency and zoledronate on bone tissue mineral distribution
    • Brennan M, Gleeson J, O'Brien F, McNamara L. Effects of ageing, prolonged estrogen deficiency and zoledronate on bone tissue mineral distribution. J Mech Behav Biomed Mater 2014; 29: 161–170.
    • (2014) J Mech Behav Biomed Mater , vol.29 , pp. 161-170
    • Brennan, M.1    Gleeson, J.2    O'Brien, F.3    McNamara, L.4
  • 40
    • 13244272104 scopus 로고    scopus 로고
    • Expression of the receptor of advanced glycation end products in gingival tissues of type 2 diabetes patients with chronic periodontal disease: a study utilizing immunohistochemistry and RT-PCR
    • Katz J, Bhattacharyya I, Farkhondeh-Kish F, Perez F, Caudle R, Heft M. Expression of the receptor of advanced glycation end products in gingival tissues of type 2 diabetes patients with chronic periodontal disease: a study utilizing immunohistochemistry and RT-PCR. J Clin Periodontol 2005; 32: 40–44.
    • (2005) J Clin Periodontol , vol.32 , pp. 40-44
    • Katz, J.1    Bhattacharyya, I.2    Farkhondeh-Kish, F.3    Perez, F.4    Caudle, R.5    Heft, M.6
  • 41
    • 84876792272 scopus 로고    scopus 로고
    • Gingival advanced glycation end-products in diabetes mellitus-associated chronic periodontitis: an immunohistochemical study
    • Zizzi A, Tirabassi G, Aspriello S, Piemontese M, Rubini C, Lucarini G. Gingival advanced glycation end-products in diabetes mellitus-associated chronic periodontitis: an immunohistochemical study. J Periodontal Res 2013; 48: 293–301.
    • (2013) J Periodontal Res , vol.48 , pp. 293-301
    • Zizzi, A.1    Tirabassi, G.2    Aspriello, S.3    Piemontese, M.4    Rubini, C.5    Lucarini, G.6
  • 42
    • 84994716324 scopus 로고    scopus 로고
    • Cytokine profile in chronic periodontitis patients with and without obesity: a systematic review and meta-analysis
    • Akram Z, Abduljabbar T, Abu-Hassan MI, Javed F, Vohra F. Cytokine profile in chronic periodontitis patients with and without obesity: a systematic review and meta-analysis. Dis Markers 2016. doi:10.1155/2016/4801418.
    • (2016) Dis Markers
    • Akram, Z.1    Abduljabbar, T.2    Abu-Hassan, M.I.3    Javed, F.4    Vohra, F.5
  • 43
    • 84961821148 scopus 로고    scopus 로고
    • Efficacy of non-surgical periodontal therapy in the management of chronic periodontitis among obese and non-obese patients: a systematic review and meta-analysis
    • Akram Z, Safii SH, Vaithilingam RD, Baharuddin NA, Javed F, Vohra F. Efficacy of non-surgical periodontal therapy in the management of chronic periodontitis among obese and non-obese patients: a systematic review and meta-analysis. Clin Oral Investig 2016; 20: 903–914.
    • (2016) Clin Oral Investig , vol.20 , pp. 903-914
    • Akram, Z.1    Safii, S.H.2    Vaithilingam, R.D.3    Baharuddin, N.A.4    Javed, F.5    Vohra, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.