메뉴 건너뛰기




Volumn 83, Issue 10, 2012, Pages 1322-1328

Local drug delivery of alendronate gel for the treatment of patients with chronic periodontitis with diabetes mellitus: A double-masked controlled clinical trial

Author keywords

Alendronate; Bone regeneration; Chronic periodontitis; Diabetes mellitus; Regeneration

Indexed keywords

ALENDRONIC ACID; BONE DENSITY CONSERVATION AGENT;

EID: 84867169921     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2012.110292     Document Type: Article
Times cited : (46)

References (43)
  • 1
    • 25844460542 scopus 로고    scopus 로고
    • Host response modulation in the management of periodontal diseases
    • Salvi GE, Lang NP. Host response modulation in the management of periodontal diseases. J Clin Periodontol 2005;32(Suppl. 6):108-129.
    • (2005) J Clin Periodontol , vol.32 , Issue.SUPPL. 6 , pp. 108-129
    • Salvi, G.E.1    Lang, N.P.2
  • 2
    • 20644434164 scopus 로고    scopus 로고
    • Etiology and pathogenesis of periodontal diseases
    • v
    • Tatakis DN, Kumar PS. Etiology and pathogenesis of periodontal diseases. Dent Clin North Am 2005;49: 491-516, v.
    • (2005) Dent Clin North Am , vol.49 , pp. 491-516
    • Tatakis, D.N.1    Kumar, P.S.2
  • 3
    • 33748575279 scopus 로고    scopus 로고
    • American Academy of Periodontology commissioned paper. Diabetes mellitus and periodontal diseases
    • Mealey BL, Oates TW. American Academy of Periodontology commissioned paper. Diabetes mellitus and periodontal diseases. J Periodontol 2006;77:1289-1303.
    • (2006) J Periodontol , vol.77 , pp. 1289-1303
    • Mealey, B.L.1    Oates, T.W.2
  • 4
    • 42449114509 scopus 로고    scopus 로고
    • Diabetes mellitus and inflammatory periodontal diseases
    • Mealey BL, Rose LF. Diabetes mellitus and inflammatory periodontal diseases. Curr Opin Endocrinol Diabetes Obes 2008;15:135-141.
    • (2008) Curr Opin Endocrinol Diabetes Obes , vol.15 , pp. 135-141
    • Mealey, B.L.1    Rose, L.F.2
  • 5
    • 0034704598 scopus 로고    scopus 로고
    • Infections associated with diabetes mellitus
    • Mangan D, Selwitz RH, Genco R. Infections associated with diabetes mellitus. N Engl J Med 2000;342:896.
    • (2000) N Engl J Med , vol.342 , pp. 896
    • Mangan, D.1    Selwitz, R.H.2    Genco, R.3
  • 6
    • 0024219149 scopus 로고
    • CPITN assessment of periodontal disease in diabetic patients
    • BacićM, Plancak D, GranićM. CPITN assessment of periodontal disease in diabetic patients. J Periodontol 1988;59:816-822.
    • (1988) J Periodontol , vol.59 , pp. 816-822
    • Bacićm1    Plancak, D.2    Granićm3
  • 7
    • 0026113065 scopus 로고
    • Periodontal disease in non-insulin-dependent diabetes mellitus
    • Emrich LJ, Shlossman M, Genco RJ. Periodontal disease in non-insulin-dependent diabetes mellitus. J Periodontol 1991;62:123-131.
    • (1991) J Periodontol , vol.62 , pp. 123-131
    • Emrich, L.J.1    Shlossman, M.2    Genco, R.J.3
  • 9
    • 0027633619 scopus 로고
    • Long-term control of diabetes mellitus and periodontitis
    • Tervonen T, Oliver RC. Long-term control of diabetes mellitus and periodontitis. J Clin Periodontol 1993;20: 431-435.
    • (1993) J Clin Periodontol , vol.20 , pp. 431-435
    • Tervonen, T.1    Oliver, R.C.2
  • 10
    • 0026365920 scopus 로고
    • Bone and biologically compatible materials in dentistry
    • Binderman I. Bone and biologically compatible materials in dentistry. Curr Opin Dent 1991;1:836-840.
    • (1991) Curr Opin Dent , vol.1 , pp. 836-840
    • Binderman, I.1
  • 11
    • 0026721147 scopus 로고
    • The bone morphogenetic protein family and osteogenesis
    • Wozney JM. The bone morphogenetic protein family and osteogenesis. Mol Reprod Dev 1992;32:160-167.
    • (1992) Mol Reprod Dev , vol.32 , pp. 160-167
    • Wozney, J.M.1
  • 12
  • 13
    • 0028303357 scopus 로고
    • Duration of the effects of intravenous alendronate in postmenopausal women and in patients with primary hyperparathyroidism and Paget's disease of bone
    • Adami S, Zamberlan N, Mian M, et al. Duration of the effects of intravenous alendronate in postmenopausal women and in patients with primary hyperparathyroidism and Paget's disease of bone. Bone Miner 1994;25:75-82.
    • (1994) Bone Miner , vol.25 , pp. 75-82
    • Adami, S.1    Zamberlan, N.2    Mian, M.3
  • 14
    • 0028851590 scopus 로고
    • Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis
    • The Alendronate Phase III Osteoporosis Treatment Study Group
    • Liberman UA, Weiss SR, Bröll J, et al; The Alendronate Phase III Osteoporosis Treatment Study Group. Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. N Engl J Med 1995;333:1437-1443.
    • (1995) N Engl J Med , vol.333 , pp. 1437-1443
    • Liberman, U.A.1    Weiss, S.R.2    Bröll, J.3
  • 16
    • 0037263826 scopus 로고    scopus 로고
    • The effect of alendronate sodium on alveolar bone loss in periodontitis (clinical trial)
    • El-Shinnawi UM, El-Tantawy SI. The effect of alendronate sodium on alveolar bone loss in periodontitis (clinical trial). J Int Acad Periodontol 2003;5:5-10.
    • (2003) J Int Acad Periodontol , vol.5 , pp. 5-10
    • El-Shinnawi, U.M.1    El-Tantawy, S.I.2
  • 17
    • 23044488738 scopus 로고    scopus 로고
    • Bisphosphonate therapy improves the outcome of conventional periodontal treatment: Results of a 12-month, randomized, placebo-controlled study
    • Lane N, Armitage GC, Loomer P, et al. Bisphosphonate therapy improves the outcome of conventional periodontal treatment: Results of a 12-month, randomized, placebo-controlled study. J Periodontol 2005;76: 1113-1122.
    • (2005) J Periodontol , vol.76 , pp. 1113-1122
    • Lane, N.1    Armitage, G.C.2    Loomer, P.3
  • 20
    • 0027986414 scopus 로고
    • Histomorphometrical analysis of the effects of the bisphosphonate alendronate on bone loss caused by experimental periodontitis in monkeys
    • Weinreb M, Quartuccio H, Seedor JG, et al. Histomorphometrical analysis of the effects of the bisphosphonate alendronate on bone loss caused by experimental periodontitis in monkeys. J Periodontal Res 1994;29:35-40.
    • (1994) J Periodontal Res , vol.29 , pp. 35-40
    • Weinreb, M.1    Quartuccio, H.2    Seedor, J.G.3
  • 21
    • 0028872059 scopus 로고
    • The effect of bisphosphonate on alveolar bone resorption following mucoperiosteal flap surgery in the mandible of rats
    • Yaffe A, Fine N, Alt I, Binderman I. The effect of bisphosphonate on alveolar bone resorption following mucoperiosteal flap surgery in the mandible of rats. J Periodontol 1995;66:999-1003.
    • (1995) J Periodontol , vol.66 , pp. 999-1003
    • Yaffe, A.1    Fine, N.2    Alt, I.3    Binderman, I.4
  • 22
    • 0028128128 scopus 로고
    • Regional accelerated phenomenon in the mandible following mucoperiosteal flap surgery
    • Yaffe A, Fine N, Binderman I. Regional accelerated phenomenon in the mandible following mucoperiosteal flap surgery. J Periodontol 1994;65:79-83.
    • (1994) J Periodontol , vol.65 , pp. 79-83
    • Yaffe, A.1    Fine, N.2    Binderman, I.3
  • 23
    • 22144480665 scopus 로고    scopus 로고
    • Formulation and evaluation of alendronate sodium gel for the treatment of bone resorptive lesions in periodontitis
    • Reddy GT, Kumar TM, Veena KM. Formulation and evaluation of alendronate sodium gel for the treatment of bone resorptive lesions in periodontitis. Drug Deliv 2005;12:217-222.
    • (2005) Drug Deliv , vol.12 , pp. 217-222
    • Reddy, G.T.1    Kumar, T.M.2    Veena, K.M.3
  • 24
    • 0033848045 scopus 로고    scopus 로고
    • Effectiveness of local delivery of alendronate in reducing alveolar bone loss following periodontal surgery in rats
    • Binderman I, Adut M, Yaffe A. Effectiveness of local delivery of alendronate in reducing alveolar bone loss following periodontal surgery in rats. J Periodontol 2000; 71:1236-1240.
    • (2000) J Periodontol , vol.71 , pp. 1236-1240
    • Binderman, I.1    Adut, M.2    Yaffe, A.3
  • 25
    • 0030798645 scopus 로고    scopus 로고
    • Local delivery of an amino bisphosphonate prevents the resorptive phase of alveolar bone following mucoperiosteal flap surgery in rats
    • Yaffe A, Iztkovich M, Earon Y, Alt I, Lilov R, Binderman I. Local delivery of an amino bisphosphonate prevents the resorptive phase of alveolar bone following mucoperiosteal flap surgery in rats. J Periodontol 1997;68: 884-889.
    • (1997) J Periodontol , vol.68 , pp. 884-889
    • Yaffe, A.1    Iztkovich, M.2    Earon, Y.3    Alt, I.4    Lilov, R.5    Binderman, I.6
  • 26
    • 33947707231 scopus 로고    scopus 로고
    • Effect of long-term oral bisphosphonates on implant wound healing: Literature review and a case report
    • Wang HL, Weber D, McCauley LK. Effect of long-term oral bisphosphonates on implant wound healing: Literature review and a case report. J Periodontol 2007;78: 584-594.
    • (2007) J Periodontol , vol.78 , pp. 584-594
    • Wang, H.L.1    Weber, D.2    McCauley, L.K.3
  • 27
    • 33646942734 scopus 로고    scopus 로고
    • Oral post-surgical complications following the administration of bisphosphonates given for osteopenia related to malignancy
    • Soileau KM. Oral post-surgical complications following the administration of bisphosphonates given for osteopenia related to malignancy. J Periodontol 2006;77:738-743.
    • (2006) J Periodontol , vol.77 , pp. 738-743
    • Soileau, K.M.1
  • 28
    • 0024100710 scopus 로고
    • Remodelling of interdental alveolar bone after periodontal flap procedures assessed by means of computer-assisted densitometric image analysis (CADIA)
    • Brägger U, Pasquali L, Kornman KS. Remodelling of interdental alveolar bone after periodontal flap procedures assessed by means of computer-assisted densitometric image analysis (CADIA). J Clin Periodontol 1988;15:558-564.
    • (1988) J Clin Periodontol , vol.15 , pp. 558-564
    • Brägger, U.1    Pasquali, L.2    Kornman, K.S.3
  • 29
    • 0015305425 scopus 로고
    • Alveolar crest reduction following full and partial thickness flaps
    • Wood DL, Hoag PM, Donnenfeld OW, Rosenfeld LD. Alveolar crest reduction following full and partial thickness flaps. J Periodontol 1972;43:141-144.
    • (1972) J Periodontol , vol.43 , pp. 141-144
    • Wood, D.L.1    Hoag, P.M.2    Donnenfeld, O.W.3    Rosenfeld, L.D.4
  • 30
    • 84863393245 scopus 로고    scopus 로고
    • Clinical efficacy of 1% alendronate gel as local drug delivery system in the treatment of chronic periodontitis: A randomized controlled clinical trial
    • Sharma A, Pradeep AR. Clinical efficacy of 1% alendronate gel as local drug delivery system in the treatment of chronic periodontitis: A randomized controlled clinical trial. J Periodontol 2012;83:11-18.
    • (2012) J Periodontol , vol.83 , pp. 11-18
    • Sharma, A.1    Pradeep, A.R.2
  • 31
    • 84856002448 scopus 로고    scopus 로고
    • Clinical efficacy of 1% alendronate gel in adjunct to mechanotherapy in the treatment of aggressive periodontitis: A randomized controlled clinical trial
    • Sharma A, Pradeep AR. Clinical efficacy of 1% alendronate gel in adjunct to mechanotherapy in the treatment of aggressive periodontitis: A randomized controlled clinical trial. J Periodontol 2012;83:19-26.
    • (2012) J Periodontol , vol.83 , pp. 19-26
    • Sharma, A.1    Pradeep, A.R.2
  • 32
    • 78651276631 scopus 로고    scopus 로고
    • Diagnosis and classification of diabetes mellitus
    • American Diabetes Association
    • American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 2011; 34(Suppl. 1):S62-S69.
    • (2011) Diabetes Care , vol.34 , Issue.SUPPL. 1
  • 33
    • 0023583441 scopus 로고
    • The microbiota associated with successful or failing osseointegrated titanium implants
    • Mombelli A, van Oosten MA, Schurch E, Lang NP. The microbiota associated with successful or failing osseointegrated titanium implants. Oral Microbiol Immunol 1987;2:145-151.
    • (1987) Oral Microbiol Immunol , vol.2 , pp. 145-151
    • Mombelli, A.1    Van Oosten, M.A.2    Schurch, E.3    Lang, N.P.4
  • 34
    • 75949163484 scopus 로고
    • Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition
    • Silness J, Löe H. Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 1964;22:121-135.
    • (1964) Acta Odontol Scand , vol.22 , pp. 121-135
    • Silness, J.1    Löe, H.2
  • 35
    • 80053605018 scopus 로고    scopus 로고
    • Autologous platelet-rich fibrin in the treatment of mandibular degree II furcation defects: A randomized clinical trial
    • Pradeep AR, Sharma A. Autologous platelet-rich fibrin in the treatment of mandibular degree II furcation defects: A randomized clinical trial. J Periodontol. 2011;82: 1396-1403.
    • (2011) J Periodontol. , vol.82 , pp. 1396-1403
    • Pradeep, A.R.1    Sharma, A.2
  • 36
    • 0034966432 scopus 로고    scopus 로고
    • Clinical and radiological improvement of periodontal disease in patients with type 2 diabetes mellitus treated with alendronate: A randomized, placebo-controlled trial
    • Rocha M, Nava LE, Vázquez de la Torre C, Sánchez- Márin F, Garay-Sevilla ME, Malacara JM. Clinical and radiological improvement of periodontal disease in patients with type 2 diabetes mellitus treated with alendronate: A randomized, placebo-controlled trial. J Periodontol 2001;72:204-209.
    • (2001) J Periodontol , vol.72 , pp. 204-209
    • Rocha, M.1    Nava, L.E.2    Vázquez De La Torre, C.3    Sánchez- Márin, F.4    Garay-Sevilla, M.E.5    Malacara, J.M.6
  • 38
    • 0034305122 scopus 로고    scopus 로고
    • Local antimicrobial therapies in periodontal disease
    • Kinane DF. Local antimicrobial therapies in periodontal disease. Ann R Australas Coll Dent Surg 2000;15: 57-60.
    • (2000) Ann R Australas Coll Dent Surg , vol.15 , pp. 57-60
    • Kinane, D.F.1
  • 39
    • 0029258603 scopus 로고
    • The role of antibiotics in the treatment of periodontitis (Part 2 - Controlled drug delivery)
    • Needleman IG, Pandya NV, Smith SR, Foyle DM. The role of antibiotics in the treatment of periodontitis (Part 2 - Controlled drug delivery). Eur J Prosthodont Restor Dent 1995;3:111-117.
    • (1995) Eur J Prosthodont Restor Dent , vol.3 , pp. 111-117
    • Needleman, I.G.1    Pandya, N.V.2    Smith, S.R.3    Foyle, D.M.4
  • 41
    • 0035213275 scopus 로고    scopus 로고
    • Rheological characterization of bioadhesive, antimicrobial, semisolids designed for the treatment of periodontal diseases: Transient and dynamic viscoelastic and continuous shear analysis
    • Jones DS, Brown AF, Woolfson AD. Rheological characterization of bioadhesive, antimicrobial, semisolids designed for the treatment of periodontal diseases: Transient and dynamic viscoelastic and continuous shear analysis. J Pharm Sci 2001;90:1978-1990.
    • (2001) J Pharm Sci , vol.90 , pp. 1978-1990
    • Jones, D.S.1    Brown, A.F.2    Woolfson, A.D.3
  • 42
    • 1542614043 scopus 로고    scopus 로고
    • Novel mucoadhesive buccal formulation containing metronidazole for the treatment of periodontal disease
    • Perioli L, Ambrogi V, Rubini D, et al. Novel mucoadhesive buccal formulation containing metronidazole for the treatment of periodontal disease. J Control Release 2004;95:521-533.
    • (2004) J Control Release , vol.95 , pp. 521-533
    • Perioli, L.1    Ambrogi, V.2    Rubini, D.3
  • 43
    • 0030469411 scopus 로고    scopus 로고
    • Development and mechanical characterization of bioadhesive semi-solid, polymeric systems containing tetracycline for the treatment of periodontal diseases
    • Jones DS, Woolfson AD, Djokic J, Coulter WA. Development and mechanical characterization of bioadhesive semi-solid, polymeric systems containing tetracycline for the treatment of periodontal diseases. Pharm Res 1996;13:1734-1738.
    • (1996) Pharm Res , vol.13 , pp. 1734-1738
    • Jones, D.S.1    Woolfson, A.D.2    Djokic, J.3    Coulter, W.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.