Impairment on the lateral mobility induced by structural changes underlies the functional deficiency of the lupusassociated polymorphism FcγRIIB-T232

Journal of Experimental Medicine

Volumn 213, Issue 12, 2016, Pages 2707-2727

  Xu, Liling ^a   Xia, Mengdie ^b   Guo, Jun ^c   Sun, Xiaolin ^d   Li, Hua ^c   XuC , Chenguang ^a   Gu, Xiaomei ^a   Zhang, Haowen ^a   Yi, Junyang ^a   Fang, Yan ^a   Xie, Hengyi ^a   Wang, Jing ^a   Shen, Zhixun ^a   Xue, Boxin ^e   Sun, Yujie ^e   Meckel, Tobias ^f   Chen, Ying Hua ^a   Hu, Zhibin ^g   Li, Zhanguo ^d   Xu, Chenqi ^c,h   Gong, Haipeng ^b   Liu, Wanli ^a   more..

^a Tsinghua University   (China)

^b TSINGHUA UNIVERSITY   (China)

^c INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^d PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

^e PEKING UNIVERSITY   (China)

^f DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

^g NANJING MEDICAL UNIVERSITY   (China)

^h SHANGHAITECH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD86 ANTIGEN; FC RECEPTOR IIB; IMMUNOGLOBULIN G ANTIBODY; ANTIGEN ANTIBODY COMPLEX; FC RECEPTOR; FCGR2B PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE LIPID;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; GENE FUNCTION; GENE STRUCTURE; GENETIC POLYMORPHISM; HUMAN; LUPUS VULGARIS; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DOMAIN; SINGLE NUCLEOTIDE POLYMORPHISM; AMINO ACID SEQUENCE; B LYMPHOCYTE; BIOLOGICAL MODEL; CELL CULTURE; CELL LINE; CELL MEMBRANE; CHEMICAL PHENOMENA; CHEMISTRY; DIFFUSION; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GENETICS; METABOLISM; MONOCYTE; PROTEIN SECONDARY STRUCTURE; SINGLE MOLECULE IMAGING; SYSTEMIC LUPUS ERYTHEMATOSUS;

AMINO ACID SEQUENCE; ANTIGEN-ANTIBODY COMPLEX; B-LYMPHOCYTES; CELL LINE; CELL MEMBRANE; CELLS, CULTURED; DIFFUSION; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE LIPIDS; MODELS, BIOLOGICAL; MOLECULAR DYNAMICS SIMULATION; MONOCYTES; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, ANTIGEN, B-CELL; RECEPTORS, IGG; SINGLE MOLECULE IMAGING;

EID: 84999810249     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20160528     Document Type: Article

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