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Volumn 24, Issue 4, 2016, Pages 458-472

Microparticles as controlled drug delivery carrier for the treatment of ulcerative colitis: A brief review

Author keywords

Colon; Inflammatory bowel disease; Multiparticulate carrier; pH sensitive polymer; Ulcerative colitis

Indexed keywords

ADALIMUMAB; AZATHIOPRINE; BALSALAZIDE; CELLULOSE; CHITOSAN; CIPROFLOXACIN; COPOLYMER; DEOXYGLUCOSE; DEXAMETHASONE; DEXAMETHASONE SODIUM PHOSPHATE; DRUG CARRIER; EUDRAGIT; GUAR GUM; HYDROXYPROPYLMETHYLCELLULOSE; INFLIXIMAB; MESALAZINE; METHACRYLIC ACID; METHOTREXATE; METRONIDAZOLE; MICROPARTICLE CARRIER; MICROSPHERE; NANOCARRIER; NANOSPHERE; OLSALAZINE; POLYMER; PREDNISONE; PRODRUG; SALAZOSULFAPYRIDINE; SOLVENT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84999041260     PISSN: 13190164     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsps.2014.10.001     Document Type: Review
Times cited : (119)

References (96)
  • 2
    • 0036457057 scopus 로고    scopus 로고
    • Inflammatory bowel disease: new insights into pathogenesis and treatment
    • Ardizzone, S., Porro, G.B., Inflammatory bowel disease: new insights into pathogenesis and treatment. J. Intern. Med. 252:6 (2002), 475–496.
    • (2002) J. Intern. Med. , vol.252 , Issue.6 , pp. 475-496
    • Ardizzone, S.1    Porro, G.B.2
  • 3
    • 0027254453 scopus 로고
    • An in vivo investigation into the suitability of pH dependent polymers for colonic targeting
    • Ashford, M., Fell, J.T., Attwood, D., Sharma, H., Woodhead, P.J., An in vivo investigation into the suitability of pH dependent polymers for colonic targeting. Int. J. Pharm. 95:1 (1993), 193–199.
    • (1993) Int. J. Pharm. , vol.95 , Issue.1 , pp. 193-199
    • Ashford, M.1    Fell, J.T.2    Attwood, D.3    Sharma, H.4    Woodhead, P.J.5
  • 4
    • 73849135453 scopus 로고    scopus 로고
    • Preparation of ethylcellulose coated gelatin microspheres as a multiparticulate colonic delivery system for 5-aminosalicilic acid
    • Atyabi, F., Vahabzadeh, R., Dinarvand, R., Preparation of ethylcellulose coated gelatin microspheres as a multiparticulate colonic delivery system for 5-aminosalicilic acid. Iran. J. Pharm. Res., 2010, 81–86.
    • (2010) Iran. J. Pharm. Res. , pp. 81-86
    • Atyabi, F.1    Vahabzadeh, R.2    Dinarvand, R.3
  • 5
    • 50549187947 scopus 로고
    • Sulphasalazine and salicylazosulphadimidine in ulcerative colitis
    • Baron, J., Connell, A., Lennard-Jones, J., Avery Jones, F., Sulphasalazine and salicylazosulphadimidine in ulcerative colitis. Lancet 279:7239 (1962), 1094–1096.
    • (1962) Lancet , vol.279 , Issue.7239 , pp. 1094-1096
    • Baron, J.1    Connell, A.2    Lennard-Jones, J.3    Avery Jones, F.4
  • 6
    • 84880589703 scopus 로고    scopus 로고
    • Preparation characterization and in-vitro release studies of enteric coated gelatin capsules containing guar gum microspheres for targeted delivery of 5-fluorouracil to colon
    • Bhat, Subramanya K., Keshavayya, J., Kulkarni, Venkatrao H., Venugoapala Reddy, K.R., Kulkarni, Anandrao R., Kulkarni, Preeti V., Preparation characterization and in-vitro release studies of enteric coated gelatin capsules containing guar gum microspheres for targeted delivery of 5-fluorouracil to colon. Der Pharma Chem. 5:3 (2013), 221–231.
    • (2013) Der Pharma Chem. , vol.5 , Issue.3 , pp. 221-231
    • Bhat, S.K.1    Keshavayya, J.2    Kulkarni, V.H.3    Venugoapala Reddy, K.R.4    Kulkarni, A.R.5    Kulkarni, P.V.6
  • 7
    • 0031929292 scopus 로고    scopus 로고
    • Management of inflammatory bowel disease
    • 71-2
    • Botoman, V.A., Bonner, G.F., Botoman, D.A., Management of inflammatory bowel disease. Am. Fam. Physician 57:1 (1998), 57–68 71-2.
    • (1998) Am. Fam. Physician , vol.57 , Issue.1 , pp. 57-68
    • Botoman, V.A.1    Bonner, G.F.2    Botoman, D.A.3
  • 8
    • 0034820299 scopus 로고    scopus 로고
    • Side effects of corticosteroid therapy
    • Buchman, A.L., Side effects of corticosteroid therapy. J. Clin. Gastroenterol. 33:4 (2001), 289–294.
    • (2001) J. Clin. Gastroenterol. , vol.33 , Issue.4 , pp. 289-294
    • Buchman, A.L.1
  • 9
    • 4344602852 scopus 로고    scopus 로고
    • Guidelines for the management of inflammatory bowel disease in adults
    • Carter, M.J., Lobo, A.J., Travis, S.P., Guidelines for the management of inflammatory bowel disease in adults. Gut 53:Suppl. 5 (2004), v1–v16.
    • (2004) Gut , vol.53 , pp. v1-v16
    • Carter, M.J.1    Lobo, A.J.2    Travis, S.P.3
  • 10
    • 84999008454 scopus 로고    scopus 로고
    • Design and development of satranidazole microspheres for colon targeted drug delivery
    • Chandra, Dinesh, Yadav, Indranil Kumar, Singh, Hari Pratap, Jain, D.A., Design and development of satranidazole microspheres for colon targeted drug delivery. Int. J. Pharm. Chem. Sci., 1(3), 2012.
    • (2012) Int. J. Pharm. Chem. Sci. , vol.1 , Issue.3
    • Chandra, D.1    Yadav, I.K.2    Singh, H.P.3    Jain, D.A.4
  • 11
    • 84876556333 scopus 로고    scopus 로고
    • Eudragit S-100 coated sodium alginate microspheres of naproxen sodium: formulation, optimization and in vitro evaluation
    • Chawla, Anuj, Sharma, Pooja, Pawar, Pravin, Eudragit S-100 coated sodium alginate microspheres of naproxen sodium: formulation, optimization and in vitro evaluation. Acta Pharm. 62 (2012), 529–545.
    • (2012) Acta Pharm. , vol.62 , pp. 529-545
    • Chawla, A.1    Sharma, P.2    Pawar, P.3
  • 12
    • 0038725720 scopus 로고    scopus 로고
    • Pharmaceutical approaches to colon targeted drug delivery systems
    • Chourasia, M., Jain, S.K., Pharmaceutical approaches to colon targeted drug delivery systems. J. Pharm. Pharm. Sci. 2003:6 (2003), 33–66.
    • (2003) J. Pharm. Pharm. Sci. , vol.2003 , Issue.6 , pp. 33-66
    • Chourasia, M.1    Jain, S.K.2
  • 14
    • 84862644846 scopus 로고    scopus 로고
    • Nano-and microparticulate drug carriers for targeting of the inflamed intestinal mucosa
    • Collnot, E.-M., Ali, H., Lehr, C.-M., Nano-and microparticulate drug carriers for targeting of the inflamed intestinal mucosa. J. Control. Release 161:2 (2012), 235–246.
    • (2012) J. Control. Release , vol.161 , Issue.2 , pp. 235-246
    • Collnot, E.-M.1    Ali, H.2    Lehr, C.-M.3
  • 16
    • 0037151566 scopus 로고    scopus 로고
    • Alginate microparticles for enzyme peroral administration
    • Coppi, G., Iannuccelli, V., Bernabei, M., Cameroni, R., Alginate microparticles for enzyme peroral administration. Int. J. Pharm. 242:1 (2002), 263–266.
    • (2002) Int. J. Pharm. , vol.242 , Issue.1 , pp. 263-266
    • Coppi, G.1    Iannuccelli, V.2    Bernabei, M.3    Cameroni, R.4
  • 17
    • 84875965089 scopus 로고    scopus 로고
    • Eudragit® microparticles for the release of budesonide: a comparative study
    • Cortesi, Rita, Ravani, Laura, Menegatti, Enea, Esposito, Elisabetta, Ronconi, F., Eudragit® microparticles for the release of budesonide: a comparative study. Indian J. Pharm. Sci. 74:5 (2012), 415–421.
    • (2012) Indian J. Pharm. Sci. , vol.74 , Issue.5 , pp. 415-421
    • Cortesi, R.1    Ravani, L.2    Menegatti, E.3    Esposito, E.4    Ronconi, F.5
  • 18
    • 79955561083 scopus 로고    scopus 로고
    • Epidemiology and natural history of inflammatory bowel diseases
    • Cosnes, J., Gower-Rousseau, C., Seksik, P., Cortot, A., Epidemiology and natural history of inflammatory bowel diseases. Gastroenterology 140:6 (2011), 1785–1794.
    • (2011) Gastroenterology , vol.140 , Issue.6 , pp. 1785-1794
    • Cosnes, J.1    Gower-Rousseau, C.2    Seksik, P.3    Cortot, A.4
  • 19
    • 77953376189 scopus 로고    scopus 로고
    • Development and characterization of pectin-prednisolone microspheres for colon targeted delivery
    • Dashora, A., Jain, C.P., Development and characterization of pectin-prednisolone microspheres for colon targeted delivery. Int. J. ChemTech Res. 1:3 (2009), 51–757.
    • (2009) Int. J. ChemTech Res. , vol.1 , Issue.3 , pp. 51-757
    • Dashora, A.1    Jain, C.P.2
  • 20
    • 0033543545 scopus 로고    scopus 로고
    • Inhibition of interleukin-1-stimulated NF-κB RelA/p65 phosphorylation by mesalamine is accompanied by decreased transcriptional activity
    • Egan, L.J., Mays, D.C., Huntoon, C.J., Bell, M.P., Pike, M.G., Sandborn, W.J., et al. Inhibition of interleukin-1-stimulated NF-κB RelA/p65 phosphorylation by mesalamine is accompanied by decreased transcriptional activity. J. Biol. Chem. 274:37 (1999), 26448–26453.
    • (1999) J. Biol. Chem. , vol.274 , Issue.37 , pp. 26448-26453
    • Egan, L.J.1    Mays, D.C.2    Huntoon, C.J.3    Bell, M.P.4    Pike, M.G.5    Sandborn, W.J.6
  • 22
    • 0037203695 scopus 로고    scopus 로고
    • Oral delayed-release system based on Zn-pectinate gel (ZPG) microparticles as an alternative carrier to calcium pectinate beads for colonic drug delivery
    • El-Gibaly, I., Oral delayed-release system based on Zn-pectinate gel (ZPG) microparticles as an alternative carrier to calcium pectinate beads for colonic drug delivery. Int. J. Pharm. 232:1–2 (2002), 199–211.
    • (2002) Int. J. Pharm. , vol.232 , Issue.1-2 , pp. 199-211
    • El-Gibaly, I.1
  • 23
    • 77957357041 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor-alphaloaded Microspheres as a prospective novel treatment for Crohn's disease fistulae
    • Foong, K.S., Patel, R., Forbes, A., Day, R.M., Anti-tumor necrosis factor-alphaloaded Microspheres as a prospective novel treatment for Crohn's disease fistulae. Tissue Eng. Part C Methods 16:16 (2010), 855–864.
    • (2010) Tissue Eng. Part C Methods , vol.16 , Issue.16 , pp. 855-864
    • Foong, K.S.1    Patel, R.2    Forbes, A.3    Day, R.M.4
  • 24
    • 79953777773 scopus 로고    scopus 로고
    • Glucocorticosteroid therapy in inflammatory bowel disease: systematic review and meta-analysis
    • Ford, A.C., Bernstein, C.N., Khan, K.J., Abreu, M.T., Marshall, J.K., Talley, N.J., et al. Glucocorticosteroid therapy in inflammatory bowel disease: systematic review and meta-analysis. Am. J. Gastroenterol. 106:4 (2011), 590–599.
    • (2011) Am. J. Gastroenterol. , vol.106 , Issue.4 , pp. 590-599
    • Ford, A.C.1    Bernstein, C.N.2    Khan, K.J.3    Abreu, M.T.4    Marshall, J.K.5    Talley, N.J.6
  • 25
    • 8844286917 scopus 로고    scopus 로고
    • New oral delivery systems for treatment of inflammatory bowel disease
    • Friend, D.R., New oral delivery systems for treatment of inflammatory bowel disease. Adv. Drug Deliv. Rev. 57:2 (2005), 247–265.
    • (2005) Adv. Drug Deliv. Rev. , vol.57 , Issue.2 , pp. 247-265
    • Friend, D.R.1
  • 26
    • 0034690954 scopus 로고    scopus 로고
    • Preparation of enteric coated timed-release press-coated tablets and evaluation of their function by in vitro and in vivo tests for colon targeting
    • Fukui, E., Miyamura, N., Uemura, K., Kobayashi, M., Preparation of enteric coated timed-release press-coated tablets and evaluation of their function by in vitro and in vivo tests for colon targeting. Int. J. Pharm. 204:1 (2000), 7–15.
    • (2000) Int. J. Pharm. , vol.204 , Issue.1 , pp. 7-15
    • Fukui, E.1    Miyamura, N.2    Uemura, K.3    Kobayashi, M.4
  • 27
    • 85047690640 scopus 로고    scopus 로고
    • Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis
    • Fuss, I.J., Heller, F., Boirivant, M., Leon, F., Yoshida, M., Fichtner-Feigl, S., et al. Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis. J. Clin. Invest. 113:10 (2004), 1490–1497.
    • (2004) J. Clin. Invest. , vol.113 , Issue.10 , pp. 1490-1497
    • Fuss, I.J.1    Heller, F.2    Boirivant, M.3    Leon, F.4    Yoshida, M.5    Fichtner-Feigl, S.6
  • 28
    • 84930037564 scopus 로고    scopus 로고
    • Development of mucoadhesive microsphere for colon delivery
    • Gawde, Preeti, Agrawal, Shikha, Jain, Prabhat, Development of mucoadhesive microsphere for colon delivery. Int. J. Pharm. Biol. Arch. 3:3 (2012), 440–442.
    • (2012) Int. J. Pharm. Biol. Arch. , vol.3 , Issue.3 , pp. 440-442
    • Gawde, P.1    Agrawal, S.2    Jain, P.3
  • 29
    • 0031172207 scopus 로고    scopus 로고
    • There are various methods for the preparation of nanoparticles which includes ionic gelation method, complex coacervation, emulsion cross linking and spray drying
    • Ghandehari, H., Kopeckova, P., Kopecek, J., There are various methods for the preparation of nanoparticles which includes ionic gelation method, complex coacervation, emulsion cross linking and spray drying. Biomaterials 18 (1997), 861–872.
    • (1997) Biomaterials , vol.18 , pp. 861-872
    • Ghandehari, H.1    Kopeckova, P.2    Kopecek, J.3
  • 30
    • 77953448626 scopus 로고    scopus 로고
    • A comparative review of recently developed particulate drug carrier systems. Taxonomy upgrade extras
    • Gilhotra, Ritu Mehra, Bhardwaj, Vishv Priya, Mishra, D.N., A comparative review of recently developed particulate drug carrier systems. Taxonomy upgrade extras. Target. Drug Deliv. Syst., 7(3), 2009.
    • (2009) Target. Drug Deliv. Syst. , vol.7 , Issue.3
    • Gilhotra, R.M.1    Bhardwaj, V.P.2    Mishra, D.N.3
  • 31
    • 80052443097 scopus 로고    scopus 로고
    • Enhanced transferrin receptor expression by proinflammatory cytokines in enterocytes as a means for local delivery of drugs to inflamed gut mucosa
    • Harel, E., Rubinstein, A., Nissan, A., Khazanov, E., Nadler Milbauer, M., Barenholz, Y., Tirosh, B., Enhanced transferrin receptor expression by proinflammatory cytokines in enterocytes as a means for local delivery of drugs to inflamed gut mucosa. PLoS One, 6, 2011, e24202.
    • (2011) PLoS One , vol.6 , pp. e24202
    • Harel, E.1    Rubinstein, A.2    Nissan, A.3    Khazanov, E.4    Nadler Milbauer, M.5    Barenholz, Y.6    Tirosh, B.7
  • 32
    • 84998540519 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of combined time and pH dependent oral colon targeted prednisolone microspheres
    • Hashem, Fahima M., Shaker, Dalia S., Nasr, Mohamed, Ragaey, Reem, In vitro and in vivo evaluation of combined time and pH dependent oral colon targeted prednisolone microspheres. Br. J. Pharm. Res. 3:3 (2013), 20–434.
    • (2013) Br. J. Pharm. Res. , vol.3 , Issue.3 , pp. 20-434
    • Hashem, F.M.1    Shaker, D.S.2    Nasr, M.3    Ragaey, R.4
  • 33
    • 0014589722 scopus 로고
    • A new method for studying gut transit times using radioopaque markers
    • Hinton, J., Lennard-Jones, J., Young, A., A new method for studying gut transit times using radioopaque markers. Gut 10:10 (1969), 842–847.
    • (1969) Gut , vol.10 , Issue.10 , pp. 842-847
    • Hinton, J.1    Lennard-Jones, J.2    Young, A.3
  • 35
    • 10344262099 scopus 로고    scopus 로고
    • Albendazole microspheres for colonic delivery
    • Jain, Sunil K., Rai, Gopal, Saraf, D.K., Agrawal, G.P., Albendazole microspheres for colonic delivery. Pharm. Technol. 28:12 (2004), 66–71.
    • (2004) Pharm. Technol. , vol.28 , Issue.12 , pp. 66-71
    • Jain, S.K.1    Rai, G.2    Saraf, D.K.3    Agrawal, G.P.4
  • 36
    • 79952026564 scopus 로고    scopus 로고
    • Development and evaluation of gelatin microspheres of tramadol hydrochloride
    • Jeevana, B., Sunitha, J.G., Development and evaluation of gelatin microspheres of tramadol hydrochloride. J. Young Pharm. 1:1 (2009), 24–27.
    • (2009) J. Young Pharm. , vol.1 , Issue.1 , pp. 24-27
    • Jeevana, B.1    Sunitha, J.G.2
  • 37
    • 0035795021 scopus 로고    scopus 로고
    • Evaluation of an intestinal pressure-controlled colon delivery capsules prepared by a dipping method
    • Jeong, Y.-I., Ohno, T., Hu, Z., Yoshikawa, Y., Shibata, N., Nagata, S., et al. Evaluation of an intestinal pressure-controlled colon delivery capsules prepared by a dipping method. J. Control. Release 71:2 (2001), 175–182.
    • (2001) J. Control. Release , vol.71 , Issue.2 , pp. 175-182
    • Jeong, Y.-I.1    Ohno, T.2    Hu, Z.3    Yoshikawa, Y.4    Shibata, N.5    Nagata, S.6
  • 38
    • 84911460889 scopus 로고    scopus 로고
    • Magnetic microspheres as magical novel drug delivery system: a review
    • Kakar, S., Batra, D., Singh, R., Nautiyal, U., Magnetic microspheres as magical novel drug delivery system: a review. J. Acute Dis. 2:1 (2012), 1–12.
    • (2012) J. Acute Dis. , vol.2 , Issue.1 , pp. 1-12
    • Kakar, S.1    Batra, D.2    Singh, R.3    Nautiyal, U.4
  • 39
    • 0032863681 scopus 로고    scopus 로고
    • Pulmonary delivery of insulin with nebulized DL-lactide/glycolide copolymer (PLGA) nanospheres to prolong hypoglycemic effect
    • Kawashima, Y., Yamamoto, H., Takeuchi, H., Fujioka, S., Hino, T., Pulmonary delivery of insulin with nebulized DL-lactide/glycolide copolymer (PLGA) nanospheres to prolong hypoglycemic effect. J. Cont. Rel. 62 (1999), 279–287.
    • (1999) J. Cont. Rel. , vol.62 , pp. 279-287
    • Kawashima, Y.1    Yamamoto, H.2    Takeuchi, H.3    Fujioka, S.4    Hino, T.5
  • 41
    • 67349275241 scopus 로고    scopus 로고
    • Microspheres for Drug Delivery. BioMEMS and Biomedical Nanotechnology
    • Springer pp. 19–50
    • Kim, K.K., Pack, D.W., Microspheres for Drug Delivery. BioMEMS and Biomedical Nanotechnology. 2006, Springer pp. 19–50.
    • (2006)
    • Kim, K.K.1    Pack, D.W.2
  • 42
    • 0034872426 scopus 로고    scopus 로고
    • Size-dependent bioadhesion of micro- and nanoparticulate carriers to the inflamed colonic mucosa
    • Lamprecht, A., Schäfer, U., Lehr, C.-M., Size-dependent bioadhesion of micro- and nanoparticulate carriers to the inflamed colonic mucosa. Pharm. Res. 18:6 (2001), 788–793.
    • (2001) Pharm. Res. , vol.18 , Issue.6 , pp. 788-793
    • Lamprecht, A.1    Schäfer, U.2    Lehr, C.-M.3
  • 43
    • 0034756945 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease
    • Lamprecht, A., Ubrich, N., Yamamoto, H., Schäfer, U., Takeuchi, H., Maincent, P., et al. Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease. J. Pharmacol. Exp. Ther. 299:2 (2001), 75–81.
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , Issue.2 , pp. 75-81
    • Lamprecht, A.1    Ubrich, N.2    Yamamoto, H.3    Schäfer, U.4    Takeuchi, H.5    Maincent, P.6
  • 44
    • 19444381516 scopus 로고    scopus 로고
    • A pH-sensitive microsphere system for the colon delivery of tacrolimus containing nanoparticles
    • Lamprecht, A., Yamamoto, H., Takeuchi, H., Kawashima, Y., A pH-sensitive microsphere system for the colon delivery of tacrolimus containing nanoparticles. J. Control. Release 104:2 (2005), 337–346.
    • (2005) J. Control. Release , vol.104 , Issue.2 , pp. 337-346
    • Lamprecht, A.1    Yamamoto, H.2    Takeuchi, H.3    Kawashima, Y.4
  • 46
    • 84888389605 scopus 로고    scopus 로고
    • PEG-functionalized microparticles selectively target inflamed mucosa in inflammatory bowel disease
    • Lautenschläger, C., Schmidt, C., Lehr, C.-M., Fischer, D., Stallmach, A., PEG-functionalized microparticles selectively target inflamed mucosa in inflammatory bowel disease. Eur. J. Pharm. Biopharm. 85:3 (2013), 578–586.
    • (2013) Eur. J. Pharm. Biopharm. , vol.85 , Issue.3 , pp. 578-586
    • Lautenschläger, C.1    Schmidt, C.2    Lehr, C.-M.3    Fischer, D.4    Stallmach, A.5
  • 47
    • 84998645266 scopus 로고    scopus 로고
    • Time-dependent Systems for Colonic Delivery
    • Marcel Dekker New York
    • Lee, W.W., Wilson, C.G., Mukherji, G., Time-dependent Systems for Colonic Delivery. 2003, Marcel Dekker, New York.
    • (2003)
    • Lee, W.W.1    Wilson, C.G.2    Mukherji, G.3
  • 49
    • 36248938630 scopus 로고    scopus 로고
    • Ulcerative colitis: diagnosis and management
    • Liang, D., Ulcerative colitis: diagnosis and management. Hosp. Physician, 2002, 53.
    • (2002) Hosp. Physician , pp. 53
    • Liang, D.1
  • 50
    • 80054865213 scopus 로고    scopus 로고
    • Preparation and characterization of meselamine loaded PLGA nanoparticles
    • Mahajan, N.M., Sakarkar, D.M., Manmode, A.S., Preparation and characterization of meselamine loaded PLGA nanoparticles. Int. J. Pharm. Pharm. Sci., 3(4), 2011.
    • (2011) Int. J. Pharm. Pharm. Sci. , vol.3 , Issue.4
    • Mahajan, N.M.1    Sakarkar, D.M.2    Manmode, A.S.3
  • 51
    • 77951889041 scopus 로고    scopus 로고
    • Colon-specific drug delivery behavior of pH-responsive PMAA/perlite composite
    • Mahkam, Mehrdad, Vakhshouri, Laleh, Colon-specific drug delivery behavior of pH-responsive PMAA/perlite composite. Int. J. Mol. Sci. 11:4 (2010), 1546–1556.
    • (2010) Int. J. Mol. Sci. , vol.11 , Issue.4 , pp. 1546-1556
    • Mahkam, M.1    Vakhshouri, L.2
  • 52
    • 62949197149 scopus 로고    scopus 로고
    • pH-Sensitive nanospheres for colon-specific drug delivery in experimentally induced colitis rat model
    • Makhlof, A., Tozuka, Y., Takeuchi, H., pH-Sensitive nanospheres for colon-specific drug delivery in experimentally induced colitis rat model. Eur. J. Pharm. Biopharm. 72:1 (2009), 1–8.
    • (2009) Eur. J. Pharm. Biopharm. , vol.72 , Issue.1 , pp. 1-8
    • Makhlof, A.1    Tozuka, Y.2    Takeuchi, H.3
  • 53
    • 18744395801 scopus 로고    scopus 로고
    • Effect of preparation temperature in solvent evaporation process on Eudragit RS microsphere properties
    • Mateović-Rojnik, Tatjana, Frlan, Rok, Bogataj, Marija, Bukovec, Peter, Mrhar, Aleš, Effect of preparation temperature in solvent evaporation process on Eudragit RS microsphere properties. Chem. Pharm. Bull. 53:1 (2005), 143–146.
    • (2005) Chem. Pharm. Bull. , vol.53 , Issue.1 , pp. 143-146
    • Mateović-Rojnik, T.1    Frlan, R.2    Bogataj, M.3    Bukovec, P.4    Mrhar, A.5
  • 55
    • 80051493362 scopus 로고    scopus 로고
    • Current treatment of ulcerative colitis
    • Meier, J., Sturm, A., Current treatment of ulcerative colitis. World J. Gastroenterol. 17:27 (2011), 3204–3212.
    • (2011) World J. Gastroenterol. , vol.17 , Issue.27 , pp. 3204-3212
    • Meier, J.1    Sturm, A.2
  • 58
    • 77953307288 scopus 로고    scopus 로고
    • Environmental risk factors for inflammatory bowel disease
    • Molodecky, N.A., Kaplan, G.G., Environmental risk factors for inflammatory bowel disease. Gastroenterol. Hepatol., 6(5), 2010, 339.
    • (2010) Gastroenterol. Hepatol. , vol.6 , Issue.5 , pp. 339
    • Molodecky, N.A.1    Kaplan, G.G.2
  • 59
    • 83755219473 scopus 로고    scopus 로고
    • Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review
    • Molodecky, N.A., Soon, I.S., Rabi, D.M., Ghali, W.A., Ferris, M., Chernoff, G., et al. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology 142:1 (2012), 46–54.
    • (2012) Gastroenterology , vol.142 , Issue.1 , pp. 46-54
    • Molodecky, N.A.1    Soon, I.S.2    Rabi, D.M.3    Ghali, W.A.4    Ferris, M.5    Chernoff, G.6
  • 60
    • 0027230553 scopus 로고
    • Thalidomide exerts its inhibitory action on TNF-α by enhancing m RNA degradation
    • Moreira, A.L., Sampaio, E.P., Zmuidzinas, A., Frindt, P., Smith, K.A., Kaplan, G., Thalidomide exerts its inhibitory action on TNF-α by enhancing m RNA degradation. J. Exp. Med. 177:6 (1993), 1675–1680.
    • (1993) J. Exp. Med. , vol.177 , Issue.6 , pp. 1675-1680
    • Moreira, A.L.1    Sampaio, E.P.2    Zmuidzinas, A.3    Frindt, P.4    Smith, K.A.5    Kaplan, G.6
  • 61
    • 18544408493 scopus 로고    scopus 로고
    • Development of an oral drug delivery system targeting immune-regulating cells in experimental inflammatory bowel disease: a new therapeutic strategy
    • Nakase, Hiroshi, Okazaki, Kazuichi, Tabata, Yasuhiko, Uose, Suguru, Ohana, Masaya, Uchida, Kazushige, Matsushima, Yumi, Kawanami, Chiharu, Oshima, Chikashi, Ikada, Yoshito, Chiba, Tsutomu, Development of an oral drug delivery system targeting immune-regulating cells in experimental inflammatory bowel disease: a new therapeutic strategy. J. Pharmacol. Exp. Ther. 292 (2000), 5–21.
    • (2000) J. Pharmacol. Exp. Ther. , vol.292 , pp. 5-21
    • Nakase, H.1    Okazaki, K.2    Tabata, Y.3    Uose, S.4    Ohana, M.5    Uchida, K.6    Matsushima, Y.7    Kawanami, C.8    Oshima, C.9    Ikada, Y.10    Chiba, T.11
  • 62
    • 84887616757 scopus 로고    scopus 로고
    • Progression of low-grade dysplasia to advanced neoplasia based on the location and morphology of dysplasia in ulcerative colitis patients with extensive colitis under colonoscopic surveillance
    • Navaneethan, U., Jegadeesan, R., Gutierrez, N.G., Venkatesh, P.G., Hammel, J.P., Shen, B., et al. Progression of low-grade dysplasia to advanced neoplasia based on the location and morphology of dysplasia in ulcerative colitis patients with extensive colitis under colonoscopic surveillance. J. Crohns Colitis 7:12 (2013), e684–e691.
    • (2013) J. Crohns Colitis , vol.7 , Issue.12 , pp. e684-e691
    • Navaneethan, U.1    Jegadeesan, R.2    Gutierrez, N.G.3    Venkatesh, P.G.4    Hammel, J.P.5    Shen, B.6
  • 63
    • 84867027990 scopus 로고    scopus 로고
    • Mucosal healing in inflammatory bowel diseases: a systematic review
    • Neurath, M.F., Travis, S.P., Mucosal healing in inflammatory bowel diseases: a systematic review. Gut 61:11 (2012), 1619–1635.
    • (2012) Gut , vol.61 , Issue.11 , pp. 1619-1635
    • Neurath, M.F.1    Travis, S.P.2
  • 64
    • 84873451525 scopus 로고    scopus 로고
    • Pectin-HPMC E15LV Vs pH sensitive polymer coating films for delayed drug delivery to colon: a comparison of two dissolution models to assess colonic targeting performance in-vitro
    • Newton, A.M.J., Prabakaran, L., Jayaveera, K., Pectin-HPMC E15LV Vs pH sensitive polymer coating films for delayed drug delivery to colon: a comparison of two dissolution models to assess colonic targeting performance in-vitro. Int. J. Appl. Res. Nat. Prod. 5:3 (2012), 1–16.
    • (2012) Int. J. Appl. Res. Nat. Prod. , vol.5 , Issue.3 , pp. 1-16
    • Newton, A.M.J.1    Prabakaran, L.2    Jayaveera, K.3
  • 65
    • 37249092895 scopus 로고    scopus 로고
    • Gastrointestinal distribution and absorption behavior of Eudragit-coated chitosan–prednisolone conjugate microspheres in rats with TNBS-induced colitis
    • Oosegi, T., Onishi, H., Machida, Y., Gastrointestinal distribution and absorption behavior of Eudragit-coated chitosan–prednisolone conjugate microspheres in rats with TNBS-induced colitis. Int. J. Pharm. 348:1 (2008), 80–88.
    • (2008) Int. J. Pharm. , vol.348 , Issue.1 , pp. 80-88
    • Oosegi, T.1    Onishi, H.2    Machida, Y.3
  • 66
    • 13744255984 scopus 로고    scopus 로고
    • Safety and efficacy of adalimumab (D2E7) in Crohn's disease patients with an attenuated response to infliximab
    • Papadakis, K.A., Shaye, O.A., Vasiliauskas, E.A., Ippoliti, A., Dubinsky, M.C., Birt, J., et al. Safety and efficacy of adalimumab (D2E7) in Crohn's disease patients with an attenuated response to infliximab. Am. J. Gastroenterol. 100:1 (2005), 75–79.
    • (2005) Am. J. Gastroenterol. , vol.100 , Issue.1 , pp. 75-79
    • Papadakis, K.A.1    Shaye, O.A.2    Vasiliauskas, E.A.3    Ippoliti, A.4    Dubinsky, M.C.5    Birt, J.6
  • 67
    • 34548214206 scopus 로고    scopus 로고
    • Therapeutic opportunities in colon-specific drug-delivery systems
    • Patel, M., Shah, T., Amin, A., Therapeutic opportunities in colon-specific drug-delivery systems. Crit. Rev. Ther. Drug Carrier Syst., 24(2), 2007.
    • (2007) Crit. Rev. Ther. Drug Carrier Syst. , vol.24 , Issue.2
    • Patel, M.1    Shah, T.2    Amin, A.3
  • 68
    • 85068618520 scopus 로고    scopus 로고
    • Colon targeted drug delivery systems: a review on primary and novel approaches
    • Philip, A.K., Philip, B., Colon targeted drug delivery systems: a review on primary and novel approaches. Oman Med. J., 25(2), 2010, 79.
    • (2010) Oman Med. J. , vol.25 , Issue.2 , pp. 79
    • Philip, A.K.1    Philip, B.2
  • 69
    • 84886293820 scopus 로고    scopus 로고
    • Formulation and evaluation of coated microspheres for colon targeting
    • Raj, Behin Sundara, Shanthi, Nair, Rajesh Sreedharan, Samraj, Punitha Isaac, Vidya, Formulation and evaluation of coated microspheres for colon targeting. J. Appl. Pharm. Sci. 3:8 (2013), 68–S74.
    • (2013) J. Appl. Pharm. Sci. , vol.3 , Issue.8 , pp. 68-S74
    • Raj, B.S.1    Shanthi2    Nair, R.S.3    Samraj, P.I.4    Vidya5
  • 70
    • 84875890993 scopus 로고    scopus 로고
    • Preparation and in-vitro characterization of ethyl cellulose coated pectin alginate microspheres of 5-fluorouracil for colon targeting
    • Ramana, G., Krishna, Chaitanya A., Preparation and in-vitro characterization of ethyl cellulose coated pectin alginate microspheres of 5-fluorouracil for colon targeting. J Appl. Pharm. Sci. 1:08 (2011), 70–76.
    • (2011) J Appl. Pharm. Sci. , vol.1 , Issue.8 , pp. 70-76
    • Ramana, G.1    Krishna, C.A.2
  • 71
    • 0036786888 scopus 로고    scopus 로고
    • Sulphasalazine and mesalazine: serious adverse reactions re-evaluated on the basis of suspected adverse reaction reports to the Committee on Safety of Medicines
    • Ransford, R., Langman, M., Sulphasalazine and mesalazine: serious adverse reactions re-evaluated on the basis of suspected adverse reaction reports to the Committee on Safety of Medicines. Gut 51:4 (2002), 536–539.
    • (2002) Gut , vol.51 , Issue.4 , pp. 536-539
    • Ransford, R.1    Langman, M.2
  • 72
    • 84860015067 scopus 로고    scopus 로고
    • Eudragitæ fs based colonic microparticles of metoprolol tartrate
    • Rasool, Fatima, Ahmad, Mahmood, Murtaza, Ghulam, Khan, Haji M.S., Khan, Shujaat Ali, Eudragitæ fs based colonic microparticles of metoprolol tartrate. Acta Pol. Pharm. 69:2 (2012), 347–353.
    • (2012) Acta Pol. Pharm. , vol.69 , Issue.2 , pp. 347-353
    • Rasool, F.1    Ahmad, M.2    Murtaza, G.3    Khan, H.M.S.4    Khan, S.A.5
  • 73
    • 0023920745 scopus 로고
    • Comparison of delayed release 5 aminosalicylic acid (mesalazine) and sulphasalazine in the treatment of mild to moderate ulcerative colitis relapse
    • Riley, S., Mani, V., Goodman, M., Herd, M., Dutt, S., Turnberg, L., Comparison of delayed release 5 aminosalicylic acid (mesalazine) and sulphasalazine in the treatment of mild to moderate ulcerative colitis relapse. Gut 29:5 (1988), 669–674.
    • (1988) Gut , vol.29 , Issue.5 , pp. 669-674
    • Riley, S.1    Mani, V.2    Goodman, M.3    Herd, M.4    Dutt, S.5    Turnberg, L.6
  • 74
    • 0344734115 scopus 로고    scopus 로고
    • Design of a new multiparticulate system for potential site-specific and controlled drug delivery to the colonic region
    • Rodrı́guez, M., Vila-Jato, J.L., Torres, D., Design of a new multiparticulate system for potential site-specific and controlled drug delivery to the colonic region. J. Control. Release 55:1 (1998), 7–77.
    • (1998) J. Control. Release , vol.55 , Issue.1 , pp. 7-77
    • Rodrı́guez, M.1    Vila-Jato, J.L.2    Torres, D.3
  • 75
    • 84896713816 scopus 로고    scopus 로고
    • Chronic ulcerative colitis and colorectal cancer
    • Rogler, Gerhard, Chronic ulcerative colitis and colorectal cancer. Cancer Lett. 345:2 (2014), 235–241.
    • (2014) Cancer Lett. , vol.345 , Issue.2 , pp. 235-241
    • Rogler, G.1
  • 77
    • 79952107339 scopus 로고    scopus 로고
    • Synthesis and in vitro evaluation of carboxymethyl starch–chitosan nanoparticles as drug delivery system to the colon
    • Saboktakin, M.R., Tabatabaie, R.M., Maharramov, A., Ramazanov, M.A., Synthesis and in vitro evaluation of carboxymethyl starch–chitosan nanoparticles as drug delivery system to the colon. Int. J. Biol. Macromol. 48:3 (2011), 381–385.
    • (2011) Int. J. Biol. Macromol. , vol.48 , Issue.3 , pp. 381-385
    • Saboktakin, M.R.1    Tabatabaie, R.M.2    Maharramov, A.3    Ramazanov, M.A.4
  • 78
    • 0034754477 scopus 로고    scopus 로고
    • Etanercept for active Crohn's disease: a randomized, double-blind, placebo-controlled trial
    • Sandborn, W.J., Hanauer, S.B., Katz, S., Safdi, M., Wolf, D.G., Baerg, R.D., et al. Etanercept for active Crohn's disease: a randomized, double-blind, placebo-controlled trial. Gastroenterology 121:5 (2001), 1088–1094.
    • (2001) Gastroenterology , vol.121 , Issue.5 , pp. 1088-1094
    • Sandborn, W.J.1    Hanauer, S.B.2    Katz, S.3    Safdi, M.4    Wolf, D.G.5    Baerg, R.D.6
  • 79
    • 84934927886 scopus 로고    scopus 로고
    • pH triggered delivery of curcumin from Eudragit-coated chitosan microspheres for inflammatory bowel disease: characterization and pharmacodynamic evaluation
    • (in Press)
    • Sareen, R., Jain, N., Rajkumari, A., Dhar, K.L., pH triggered delivery of curcumin from Eudragit-coated chitosan microspheres for inflammatory bowel disease: characterization and pharmacodynamic evaluation. Drug Deliv., 2014 (in Press).
    • (2014) Drug Deliv.
    • Sareen, R.1    Jain, N.2    Rajkumari, A.3    Dhar, K.L.4
  • 80
    • 0015757745 scopus 로고
    • Metabolism of foreign compounds by gastrointestinal microorganisms
    • Scheline, R.R., Metabolism of foreign compounds by gastrointestinal microorganisms. Pharmacol. Rev., 25(4), 1973, 451.
    • (1973) Pharmacol. Rev. , vol.25 , Issue.4 , pp. 451
    • Scheline, R.R.1
  • 81
    • 0023521441 scopus 로고
    • Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study
    • Schroeder, K.W., Tremaine, W.J., Ilstrup, D.M., Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study. N. Engl. J. Med. 317:26 (1987), 625–629.
    • (1987) N. Engl. J. Med. , vol.317 , Issue.26 , pp. 625-629
    • Schroeder, K.W.1    Tremaine, W.J.2    Ilstrup, D.M.3
  • 82
    • 0028964310 scopus 로고
    • The mouse/human chimeric monoclonal antibody cA2 neutralizes TNF in vitro and protects transgenic mice from cachexia and TNF lethality in vivo
    • Siegel, S.A., Shealy, D.J., Nakada, M.T., Le, J., Woulfe, D.S., Probert, L., et al. The mouse/human chimeric monoclonal antibody cA2 neutralizes TNF in vitro and protects transgenic mice from cachexia and TNF lethality in vivo. Cytokine 7:1 (1995), 15–25.
    • (1995) Cytokine , vol.7 , Issue.1 , pp. 15-25
    • Siegel, S.A.1    Shealy, D.J.2    Nakada, M.T.3    Le, J.4    Woulfe, D.S.5    Probert, L.6
  • 83
    • 34447641291 scopus 로고    scopus 로고
    • Modified-release solid formulations for colonic delivery
    • Singh, B.M., Modified-release solid formulations for colonic delivery. Recent Pat. Drug Delivery Formulation 1 (2007), 53–63.
    • (2007) Recent Pat. Drug Delivery Formulation , vol.1 , pp. 53-63
    • Singh, B.M.1
  • 84
    • 84901414702 scopus 로고    scopus 로고
    • Colon specific drug delivery systems: a review on pharmaceutical approaches with current trends
    • Sowmya, Cherukuri, Reddy, Chappidi Suryaprakash, Vishnu Priya, Neelaboina, Sandhya, Reddipalli, Komaragiri, Keerthi, Colon specific drug delivery systems: a review on pharmaceutical approaches with current trends. Int. Res. J. Pharm., 3(7), 2012, 45.
    • (2012) Int. Res. J. Pharm. , vol.3 , Issue.7 , pp. 45
    • Sowmya, C.1    Reddy, C.S.2    Vishnu Priya, N.3    Sandhya, R.4    Komaragiri, K.5
  • 85
    • 0031913741 scopus 로고    scopus 로고
    • Disruption of intestinal barrier function associated with experimental colitis: possible role of mast cells
    • Stein, J., Ries, J., Barrett, K.E., Disruption of intestinal barrier function associated with experimental colitis: possible role of mast cells. Am. J. Physiol. Gastrointest. Liver Physiol. 274:1 (1998), G203–G209.
    • (1998) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.274 , Issue.1 , pp. G203-G209
    • Stein, J.1    Ries, J.2    Barrett, K.E.3
  • 86
    • 33847381116 scopus 로고    scopus 로고
    • The fundamental basis of inflammatory bowel disease
    • Strober, W., Fuss, I., Mannon, P., The fundamental basis of inflammatory bowel disease. J. Clin. Invest. 117:3 (2007), 514–521.
    • (2007) J. Clin. Invest. , vol.117 , Issue.3 , pp. 514-521
    • Strober, W.1    Fuss, I.2    Mannon, P.3
  • 87
    • 0029123032 scopus 로고
    • Application of a spray drying technique in the production of TRH-containing injectable sustained-release microparticles of biodegradable polymers
    • Takada, S., Uda, Y., Toguchi, H., Ogawa, Y., Application of a spray drying technique in the production of TRH-containing injectable sustained-release microparticles of biodegradable polymers. PD J PhAarm. Sci. Technol. 49:4 (1995), 180–184.
    • (1995) PD J PhAarm. Sci. Technol. , vol.49 , Issue.4 , pp. 180-184
    • Takada, S.1    Uda, Y.2    Toguchi, H.3    Ogawa, Y.4
  • 88
    • 84879491455 scopus 로고    scopus 로고
    • Overcoming therapeutic obstacles in inflammatory bowel diseases: a comprehensive review on novel drug delivery strategies
    • Talaei, F., Atyabi, F., Azhdarzadeh, M., Dinarvand, R., Saadatzadeh, A., Overcoming therapeutic obstacles in inflammatory bowel diseases: a comprehensive review on novel drug delivery strategies. Eur. J. Pharm. Sci. 49:4 (2013), 712–722.
    • (2013) Eur. J. Pharm. Sci. , vol.49 , Issue.4 , pp. 712-722
    • Talaei, F.1    Atyabi, F.2    Azhdarzadeh, M.3    Dinarvand, R.4    Saadatzadeh, A.5
  • 89
    • 80455122788 scopus 로고    scopus 로고
    • Optimization of conventional therapy in patients with IBD
    • Taylor, K.M., Irving, P.M., Optimization of conventional therapy in patients with IBD. Nat. Rev. Gastroenterol. Hepatol. 8:11 (2011), 646–656.
    • (2011) Nat. Rev. Gastroenterol. Hepatol. , vol.8 , Issue.11 , pp. 646-656
    • Taylor, K.M.1    Irving, P.M.2
  • 91
    • 0032786343 scopus 로고    scopus 로고
    • Oral mesalazine for the treatment of Crohn's disease: clinical efficacy with respect to pharmacokinetic properties
    • Tromm, A., Griga, T., May, B., Oral mesalazine for the treatment of Crohn's disease: clinical efficacy with respect to pharmacokinetic properties. Hepatogastroenterology 46:30 (1998), 3124–3135.
    • (1998) Hepatogastroenterology , vol.46 , Issue.30 , pp. 3124-3135
    • Tromm, A.1    Griga, T.2    May, B.3
  • 92
    • 0031763109 scopus 로고    scopus 로고
    • Long-term treatment of ulcerative colitis with ciprofloxacin: a prospective, double-blind, placebo-controlled study
    • Turunen, U.M., Färkkilä, M.A., Hakala, K., Seppälä, K., Sivonen, A., Ögren, M., et al. Long-term treatment of ulcerative colitis with ciprofloxacin: a prospective, double-blind, placebo-controlled study. Gastroenterology 115:5 (1998), 1072–1078.
    • (1998) Gastroenterology , vol.115 , Issue.5 , pp. 1072-1078
    • Turunen, U.M.1    Färkkilä, M.A.2    Hakala, K.3    Seppälä, K.4    Sivonen, A.5    Ögren, M.6
  • 93
    • 78650500199 scopus 로고    scopus 로고
    • Microencapsulation of budesonide with dextran by spray drying technique for colon-targeted delivery: an in vitro/in vivo evaluation in induced colitis in rat
    • Varshosaz, Jaleh, Ahmadi, Fatemeh, Emami, Jaber, Tavakoli, Naser, Minaiyan, Mohsen, Mahzouni, Parvin, Dorkoosh, Farid, Microencapsulation of budesonide with dextran by spray drying technique for colon-targeted delivery: an in vitro/in vivo evaluation in induced colitis in rat. J. Microencapsul. 28:1 (2011), 2–73.
    • (2011) J. Microencapsul. , vol.28 , Issue.1 , pp. 2-73
    • Varshosaz, J.1    Ahmadi, F.2    Emami, J.3    Tavakoli, N.4    Minaiyan, M.5    Mahzouni, P.6    Dorkoosh, F.7
  • 94
    • 84999012996 scopus 로고    scopus 로고
    • Preparation of biodegradable insulin nanocapsules from biocompatible microemulsions
    • Watnasirichaikul, S., Davies, N.M., Rades, T., et al. Preparation of biodegradable insulin nanocapsules from biocompatible microemulsions. Pharm. Res. 9 (2000), 176684–176689.
    • (2000) Pharm. Res. , vol.9 , pp. 176684-176689
    • Watnasirichaikul, S.1    Davies, N.M.2    Rades, T.3
  • 95
    • 1842447648 scopus 로고    scopus 로고
    • Microcapsules: preparation by interfacial polymerization and interfacial complexation and their application
    • In: (Ed.), Microencapsulation: Methods and Industrial Applications, pp.
    • Whateley, T.L., 1996. Microcapsules: preparation by interfacial polymerization and interfacial complexation and their application. In: Benita, S. (Ed.), Microencapsulation: Methods and Industrial Applications, pp. 349–375.
    • (1996) Benita, S , pp. 349-375
    • Whateley, T.L.1


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