The preparation and evaluation of albendazole microspheres for colonic delivery

Pharmaceutical Technology

Volumn 28, Issue 12, 2004, Pages 66-71

  Jain, Sunil K ^a   Rai, Gopal ^a   Saraf, D K ^a   Agrawal, G P ^a  

^a DR H S GOUR UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CONCENTRATION (PROCESS); DRUG THERAPY; EMULSIFICATION; FLUIDS; PARTICLE SIZE ANALYSIS; POLYMERS;

EMULSIFIERS; MICROSPHERES; POLYMER CONCENTRATION;

DRUG PRODUCTS;

ALBENDAZOLE; EMULSIFYING AGENT; MICROSPHERE; POLYMER;

ANIMAL TISSUE; ARTICLE; CECUM; COLON; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG SCREENING; DRUG SYNTHESIS; INTESTINE FLUID; MALE; NONHUMAN; PARTICLE SIZE; RAT; SIMULATION;

EID: 10344262099     PISSN: 15432521     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. T.N. Tozer et al., "Colon Specific Delivery of Dexamethasone from a Glucoside Prodrug in the Guinea Pig," Pharm. Res. 8 (4), 445--454 (1991).
2. M. Ashford et al., "An In Vivo Investigation into the Suitability of pH Dependent Polymers for Colonic Targeting," Int. J. Pharm. 95, 193-199 (1993).
3. M. Marvola et al., "Enteric Polymers as Binders and Coating Materials in Multiple-Unit Site-Specific Drug Delivery Systems," Eur. J. Pharm. Sci. 7 (3), 259-267 (1999).
4. C. Gazzaniga et al., "Time Dependent Oral Delivery System for the Colon Targeting," S.T.P. Pharm. Sci. 5, 83-88 (1995).
5. L.F. Siew, A.W. Basit, and J.M. Newton, "The Properties of Amylose-Ethylcellulose Films Cast from Organic-Based Solvents as Potential Coatings for Colonic Drug Delivery," Eur. J. Pharm. Sci. 11 (2), 133-139 (2000).
6. T. Ishibashi et al., "Design and Evaluation of a New Capsule-Type Dosage Form for Colon Targeted Delivery of Drugs," Int. J. Pharm. 168, 31-40 (1998).
7. Y. Yoshikawa et al., "A Dissolution Test for a Pressure-Controlled Colon Delivery Capsule: Rotating Beads Method," J. Pharm. Pharmacol. 51 (9), 979-989 (1999).
8. L. Hovgaard and H. Brondsted, "Dextran Hydrogels for Colon-Specific Drug Delivery," J. Control. Rel., 36, 159-166 (1995).
9. P.J. Watts and L. Ilium, "Colonic Drug Delivery," Drug Dev. Ind. Pharm. 23, 893-913 (1997).
10. D. Babay, A. Hoffman, and S. Benita, "Design and Release Kinetic Pattern Evaluation of Indomethacin Microspheres," Biomaterials, 9, 482-488 (1988).
11. S. Benita, A. Hoffman, and M. Donbrow, "Microencapsulation of Paracetamol Using Polyacrylate Resins (Eudragit Retard), Kinetics of Drug Release and Evaluation of Kinetic Model," J. Pharm. Pharmacol., 37, 391-395 (1985).
12. M. Kilicarslan and T. Baykara, "The Effect of the Drug/Polymer Ratio on the Properties of the Verapamil HCl Loaded Microspheres Intended for Oral Administration," Int. J. Pharm. 252 (1-2), 99-109 (2003).
13. J. Kramer and H. Blume, "Biopharmaceutical Aspects of Multiparticulates," in Multiparticulate Oral Drug Delivery, Y. Ghebre-Sellasie, Ed. (Marcel Dekker, New York, NY, 1994), pp. 307-332.
14. J.W. Tracy and L.T. Webster, Jr., "Drugs Used in the Chemotherapy of Helminthiasis," in Goodman and Gillman's The Pharmacological Basis of Therapeutics, J.G. Hardman and L.E. Limbird, Eds. 10th ed., (McGraw-Hill, Medical Publishing Division, New York, 2001), pp. 1125-1129.
15. Y.S.R. Krishnaiah et al., "Development of Colon Targeted Oral Guar Gum Matrix Tablets of Albendazole for the Treatment of Helminthiasis," Ind. J. Pharm. Sci., 65 (4), 378-385 (2003).
16. Y.S.R. Krishnaiah et al., "Guar Gum as a Carrier for Colon Specific Delivery; Influence of Metronidazole and Tinidazole on In Vitro Release of Albendazole from Guar Gum Matrix Tablets," J. Pharm. Pharmaceut. Sci. 4 (3), 235-243 (2001). PT