Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy

Human Molecular Genetics

Volumn 25, Issue 11, 2016, Pages 2143-2157

  Israeli, Eitan ^a   Dryanovski, Dilyan I ^a   Schumacker, Paul T ^a   Chandel, Navdeep S ^a   Singer, Jeffrey D ^b   Julien, Jean P ^c   Goldman, Robert D ^a   Opal, Puneet ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b PORTLAND STATE UNIVERSITY   (United States)

^c UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; BIOENERGY; CONTROLLED STUDY; ENERGY TRANSFER; GIANT AXONAL NEUROPATHY; HUMAN; HUMAN CELL; INTERMEDIATE FILAMENT; MITOCHONDRION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; SPINAL GANGLION; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; ENERGY METABOLISM; GENETICS; METABOLISM; NERVE CELL; PATHOLOGY;

CYTOSKELETON PROTEIN; GAN PROTEIN, MOUSE; INTERMEDIATE FILAMENT PROTEIN; PROTEASOME;

ANIMALS; CYTOSKELETAL PROTEINS; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; GIANT AXONAL NEUROPATHY; HUMANS; INTERMEDIATE FILAMENT PROTEINS; INTERMEDIATE FILAMENTS; MICE; MITOCHONDRIA; NEURONS; OXIDATIVE STRESS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS;

EID: 84998962600     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddw081     Document Type: Article

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