Hyperferritinemia is a potential marker of chronic chikungunya: A retrospective study on the Island of Curaçao during the 2014–2015 outbreak

Journal of Clinical Virology

Volumn 86, Issue , 2017, Pages 31-38

  Anfasa, Fatih ^a,b   Provacia, Lisette ^c,d   GeurtsvanKessel, Corine ^a   Wever, Robert ^d   Gerstenbluth, Izzy ^c,e   Osterhaus, Albert D M E ^a,f,g   Martina, Byron E E ^a,f  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF INDONESIA   (Indonesia)

^c Curaçao BioMedical Health Research Institute   (Netherlands)

^d Medical Laboratory Services   (Netherlands)

^e Ministry of Health Welfare and Sport Netherlands   (Netherlands)

^f Artemis One Health   (Netherlands)

^g UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

Chikungunya virus; Chronic arthralgia; Cura ao; Ferritin; Neopterin

Indexed keywords

ANTIBODY; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CYCLIC CITRULLINATED PEPTIDE ANTIBODY; FERRITIN; NEOPTERIN; RHEUMATOID FACTOR; VIRUS ANTIBODY;

ARTHRALGIA; ARTHRITIS; ARTICLE; CHIKUNGUNYA; CHIKUNGUNYA VIRUS; CONTROLLED STUDY; CROSS REACTION; CURACAO; CYTOMEGALOVIRUS INFECTION; DIAGNOSTIC PROCEDURE; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE MARKER; ELISA KIT; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIDEMIC; EPSTEIN BARR VIRUS INFECTION; FERRITIN BLOOD LEVEL; FEVER; GENOTYPE; HUMAN; HYPERFERRITINEMIA; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; QUESTIONNAIRE; RASH; REAL TIME POLYMERASE CHAIN REACTION; RETROSPECTIVE STUDY; RHEUMATOID ARTHRITIS; SENSITIVITY AND SPECIFICITY; SEROLOGY; VIREMIA; VIRUS DETECTION; VIRUS DIAGNOSIS; VIRUS LOAD; VIRUS NEUTRALIZATION; BLOOD; CHRONIC DISEASE; CLASSIFICATION; GENETICS; ISOLATION AND PURIFICATION; PATHOLOGY;

ANTIBODIES, VIRAL; BIOMARKERS; CHIKUNGUNYA FEVER; CHIKUNGUNYA VIRUS; CHRONIC DISEASE; CURACAO; DISEASE OUTBREAKS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FERRITINS; GENOTYPE; HUMANS; RETROSPECTIVE STUDIES; VIRAL LOAD;

EID: 84998865150     PISSN: 13866532     EISSN: 18735967     Source Type: Journal    
DOI: 10.1016/j.jcv.2016.11.003     Document Type: Article

References (28)

1. [1] Caglioti, C., Lalle, E., Castilletti, C., Carletti, F., Capobianchi, M.R., Bordi, L., Chikungunya virus infection: an overview. New Microbiol. 36 (2013), 211–227.
2. [2] Cassadou, S., Boucau, S., Petit-Sinturel, M., Huc, P., Leparc-Goffart, I., Ledrans, M., Emergence of chikungunya fever on the French side of Saint Martin island, October to December 2013. Euro Surveill., 19, 2014.
3. [3] van den Doel, P., Volz, A., Roose, J.M., Sewbalaksing, V.D., Pijlman, G.P., van Middelkoop, I., et al. Recombinant modified vaccinia virus Ankara expressing glycoprotein E2 of Chikungunya virus protects AG129 mice against lethal challenge. PLoS Negl. Trop. Dis., 8, 2014, e3101.
4. [4] Laurent, P., Le Roux, K., Grivard, P., Bertil, G., Naze, F., Picard, M., et al. Development of a sensitive real-time reverse transcriptase PCR assay with an internal control to detect and quantify chikungunya virus. Clin. Chem. 53 (2007), 1408–1414.
5. [5] Goeijenbier, M., Aron, G., Anfasa, F., Lundkvist, A., Verner-Carlsson, J., Reusken, C.B., et al. Emerging viruses in the Republic of Suriname: retrospective and prospective study into chikungunya circulation and suspicion of Human Hantavirus Infections, 2008–2012 and 2014. Vector Borne Zoonotic Dis. 15 (2015), 611–618.
6. [6] Lim, S.M., Koraka, P., Osterhaus, A.D., Martina, B.E., Development of a strand-specific real-time qRT-PCR for the accurate detection and quantitation of West Nile virus RNA. J. Virol. Methods 194 (2013), 146–153.
7. [7] Niyas, K.P., Abraham, R., Unnikrishnan, R.N., Mathew, T., Nair, S., Manakkadan, A., et al. Molecular characterization of Chikungunya virus isolates from clinical samples and adult Aedes albopictus mosquitoes emerged from larvae from Kerala, South India. Virol. J., 7, 2010, 189.
8. [8] Sreekumar, E., Issac, A., Nair, S., Hariharan, R., Janki, M.B., Arathy, D.S., et al. Genetic characterization of 2006–2008 isolates of Chikungunya virus from Kerala, South India, by whole genome sequence analysis. Virus Genes 40 (2010), 14–27.
9. [9] Dereeper, A., Guignon, V., Blanc, G., Audic, S., Buffet, S., Chevenet, F., et al. Phylogeny.fr: robust phylogenetic analysis for the non-specialist. Nucleic Acids Res. 36 (2008), W465–W469.
10. [10] Weaver, S.C., Lecuit, M., Chikungunya virus and the global spread of a mosquito-borne disease. N. Engl. J. Med. 372 (2015), 1231–1239.
11. [11] Niedrig, M., Zeller, H., Schuffenecker, I., Drosten, C., Emmerich, P., Rumer, L., et al. International diagnostic accuracy study for the serological detection of chikungunya virus infection. Clin. Microbiol. Infect. 15 (2009), 880–884.
12. [12] Yap, G., Pok, K.Y., Lai, Y.L., Hapuarachchi, H.C., Chow, A., Leo, Y.S., et al. Evaluation of Chikungunya diagnostic assays: differences in sensitivity of serology assays in two independent outbreaks. PLoS Negl. Trop. Dis., 4, 2010, e753.
13. [13] Litzba, N., Schuffenecker, I., Zeller, H., Drosten, C., Emmerich, P., Charrel, R., et al. Evaluation of the first commercial chikungunya virus indirect immunofluorescence test. J. Virol. Methods 149 (2008), 175–179.
14. [14] Prat, C.M., Flusin, O., Panella, A., Tenebray, B., Lanciotti, R., Leparc-Goffart, I., Evaluation of commercially available serologic diagnostic tests for chikungunya virus. Emerg. Infect. Dis. 20 (2014), 2129–2132.
15. [15] Nunes, M.R., Faria, N.R., de Vasconcelos, J.M., Golding, N., Kraemer, M.U., de Oliveira, L.F., et al. Emergence and potential for spread of Chikungunya virus in Brazil. BMC Med., 13, 2015, 102.
16. [16] Tsetsarkin, K.A., Chen, R., Yun, R., Rossi, S.L., Plante, K.S., Guerbois, M., et al. Multi-peaked adaptive landscape for chikungunya virus evolution predicts continued fitness optimization in Aedes albopictus mosquitoes. Nat. Commun., 5, 2014, 4084.
17. [17] Tsetsarkin, K.A., Vanlandingham, D.L., McGee, C.E., Higgs, S., A single mutation in chikungunya virus affects vector specificity and epidemic potential. PLoS Pathog., 3, 2007, e201.
18. [18] Her, Z., Malleret, B., Chan, M., Ong, E.K., Wong, S.C., Kwek, D.J., et al. Active infection of human blood monocytes by Chikungunya virus triggers an innate immune response. J. Immunol. 184 (2010), 5903–5913.
19. [19] Labadie, K., Larcher, T., Joubert, C., Mannioui, A., Delache, B., Brochard, P., et al. Chikungunya disease in nonhuman primates involves long-term viral persistence in macrophages. J. Clin. Invest. 120 (2010), 894–906.
20. [20] Couderc, T., Chretien, F., Schilte, C., Disson, O., Brigitte, M., Guivel-Benhassine, F., et al. A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease. PLoS Pathog., 4, 2008, e29.
21. [21] Juffrie, M., Meer, G.M., Hack, C.E., Haasnoot, K., Sutaryo Veerman, A.J., et al. Inflammatory mediators in dengue virus infection in children: interleukin-6 and its relation to C-reactive protein and secretory phospholipase A2. Am. J. Trop. Med. Hyg. 65 (2001), 70–75.
22. [22] Chen, C.C., Lee, I.K., Liu, J.W., Huang, S.Y., Wang, L., Utility of C-reactive protein levels for early prediction of dengue severity in adults. Biomed Res. Int., 2015, 2015, 936062.
23. [23] Fahmy, M., Young, S.P., Modulation of iron metabolism in monocyte cell line U937 by inflammatory cytokines: changes in transferrin uptake, iron handling and ferritin mRNA. Biochem. J. 296:Pt 1 (1993), 175–181.
24. [24] Tran, T.N., Eubanks, S.K., Schaffer, K.J., Zhou, C.Y., Linder, M.C., Secretion of ferritin by rat hepatoma cells and its regulation by inflammatory cytokines and iron. Blood 90 (1997), 4979–4986.
25. [25] Rosario, C., Zandman-Goddard, G., Meyron-Holtz, E.G., D'Cruz, D.P., Shoenfeld, Y., The hyperferritinemic syndrome: macrophage activation syndrome, Still's disease, septic shock and catastrophic antiphospholipid syndrome. BMC Med., 11, 2013, 185.
26. [26] Rosario, C., Shoenfeld, Y., The hyperferritinemic syndrome. Isr. Med. Assoc. J. 16 (2014), 664–665.
27. [27] van de Weg, C.A., Huits, R.M., Pannuti, C.S., Brouns, R.M., van den Berg, R.W., van den Ham, H.J., et al. Hyperferritinaemia in dengue virus infected patients is associated with immune activation and coagulation disturbances. PLoS Negl. Trop. Dis., 8, 2014, e3214.
28. [28] van de Weg, C.A., Koraka, P., van Gorp, E.C., Mairuhu, A.T., Supriatna, M., Soemantri, A., et al. Lipopolysaccharide levels are elevated in dengue virus infected patients and correlate with disease severity. J. Clin. Virol. 53 (2012), 38–42.