Lipopolysaccharide levels are elevated in dengue virus infected patients and correlate with disease severity

Journal of Clinical Virology

Volumn 53, Issue 1, 2012, Pages 38-42

  van de Weg, Cornelia A M ^a   Koraka, Penelope ^a   van Gorp, Eric C M ^a   Mairuhu, Albert T A ^c   Supriatna, Mohamad ^b   Soemantri, Augustinus ^b   van de Vijver, David A M C ^a   Osterhaus, Albert D M E ^a   Martina, Byron E E ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b Pediatric Department   (Indonesia)

^c SLOTERVAART HOSPITAL   (Netherlands)

Author keywords

Dengue virus; LBP; Microbial translocation LPS; Neopterin; SCD14

Indexed keywords

CD14 ANTIGEN; LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE BINDING PROTEIN; NEOPTERIN;

ADOLESCENT; ARTICLE; BLOOD SAMPLING; CHILD; CONTROLLED STUDY; DENGUE; DENGUE VIRUS; DISEASE CLASSIFICATION; DISEASE SEVERITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PLASMA LEAKAGE SEVERITY SCORE; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SCORING SYSTEM; WORLD HEALTH ORGANIZATION;

ACUTE-PHASE PROTEINS; ADOLESCENT; ANTIGENS, CD14; CARRIER PROTEINS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; DENGUE; DENGUE VIRUS; FEMALE; HUMANS; INTESTINAL MUCOSA; LIPOPOLYSACCHARIDES; MALE; MEMBRANE GLYCOPROTEINS; NEOPTERIN; SEVERITY OF ILLNESS INDEX;

EID: 83355163261     PISSN: 13866532     EISSN: 18735967     Source Type: Journal    
DOI: 10.1016/j.jcv.2011.09.028     Document Type: Article

References (17)

1. Martina B.E., Koraka P., Osterhaus A.D. Dengue virus pathogenesis: an integrated view. Clin Microbiol Rev 2009, 22(October (4)):564-581.
2. Brenchley J.M., Price D.A., Schacker T.W., Asher T.E., Silvestri G., Rao S., et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 2006, 12(December (12)):1365-1371.
3. Cooke K.R., Olkiewicz K., Erickson N., Ferrara J.L. The role of endotoxin and the innate immune response in the pathophysiology of acute graft versus host disease. J Endotoxin Res 2002, 8(6):441-448.
4. Pastor Rojo O., Lopez San Roman A., Albeniz Arbizu E., de la Hera Martinez A., Ripoll Sevillano E., Albillos Martinez A. Serum lipopolysaccharide-binding protein in endotoxemic patients with inflammatory bowel disease. Inflamm Bowel Dis 2007, 13(March (3)):269-277.
5. Opal S.M., Scannon P.J., Vincent J.L., White M., Carroll S.F., Palardy J.E., et al. Relationship between plasma levels of lipopolysaccharide (LPS) and LPS-binding protein in patients with severe sepsis and septic shock. J Infect Dis 1999, 180(November (5)):1584-1589.
6. Setiati T.E., Mairuhu A.T., Koraka P., Supriatna M., Mac Gillavry M.R., Brandjes D.P., et al. Dengue disease severity in Indonesian children: an evaluation of the World Health Organization classification system. BMC Infect Dis 2007, 7:22.
7. Callahan J.D., Wu S.J., Dion-Schultz A., Mangold B.E., Peruski L.F., Watts D.M., et al. Development and evaluation of serotype- and group-specific fluorogenic reverse transcriptase PCR (TaqMan) assays for dengue virus. J Clin Microbiol 2001, 39(November (11)):4119-4124.
8. World Health Organization. Dengue hemorrhagic fever: diagnosis, treatment, prevention and control, 2nd ed. Geneva; 1997.
9. Roth R.I., Levin F.C., Levin J. Optimization of detection of bacterial endotoxin in plasma with the Limulus test. J Lab Clin Med 1990, 116(August (2)):153-161.
10. Srikiatkhachorn A., Gibbons R.V., Green S., Libraty D.H., Thomas S.J., Endy T.P., et al. Dengue hemorrhagic fever: the sensitivity and specificity of the world health organization definition for identification of severe cases of dengue in Thailand, 1994-2005. Clin Infect Dis 2010, 50(April (8)):1135-1143.
11. Kitchens R.L., Thompson P.A. Modulatory effects of sCD14 and LBP on LPS-host cell interactions. J Endotoxin Res 2005, 11(4):225-229.
12. Sandler N.G., Wand H., Roque A., Law M., Nason M.C., Nixon D.E., et al. Plasma levels of soluble CD14 independently predict mortality in HIV infection. J Infect Dis 2011, 203(March (6)):780-790.
13. Brunialti M.K., Martins P.S., Barbosa de Carvalho H., Machado F.R., Barbosa L.M., Salomao R TLR2, TLR4, CD14, CD11B, and CD11C expressions on monocytes surface and cytokine production in patients with sepsis, severe sepsis, and septic shock. Shock 2006, 25(April (4)):351-357.
14. Landmann R., Reber A.M., Sansano S., Zimmerli W. Function of soluble CD14 in serum from patients with septic shock. J Infect Dis 1996, 173(March (3)):661-668.
15. Brenchley J.M., Price D.A., Douek D.C. HIV disease: fallout from a mucosal catastrophe?. Nat Immunol 2006, 7(March (3)):235-239.
16. Babb K., Carrington C.V., Monteil M.A. A preliminary study of neopterin as a potential marker for severe dengue virus infection. Trans Roy Soc Trop Med Hyg 1999, 93(July-August (4)):447-448.
17. Chan C.P., Choi J.W., Cao K.Y., Wang M., Gao Y., Zhou D.H., et al. Detection of serum neopterin for early assessment of dengue virus infection. J Infect 2006, 53(September (3)):152-158.