Multi-peaked adaptive landscape for chikungunya virus evolution predicts continued fitness optimization in Aedes albopictus mosquitoes

Nature Communications

Volumn 5, Issue , 2014, Pages

  Tsetsarkin, Konstantin A ^a   Chen, Rubing ^a   Yun, Ruimei ^a   Rossi, Shannan L ^a   Plante, Kenneth S ^a   Guerbois, Mathilde ^a   Forrester, Naomi ^a   Perng, Guey Chuen ^b,c,d   Sreekumar, Easwaran ^e   Leal, Grace ^a   Huang, Jing ^a   Mukhopadhyay, Suchetana ^f   Weaver, Scott C ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^d NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^e RAJIV GANDHI CENTRE FOR BIOTECHNOLOGY   (India)

^f INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GLUTAMIC ACID; GLUTAMINE; GLYCOPROTEIN; GLYCOPROTEIN E2; VIRUS ENVELOPE PROTEIN;

ADAPTATION; EMERGENCE; FITNESS; LANDSCAPE; MOSQUITO; MUTATION; OPTIMIZATION; ORGANIC ACID; VIRUS;

AEDES ALBOPICTUS; ARTICLE; CHIKUNGUNYA ALPHAVIRUS; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; INDIAN OCEAN; LANDSCAPE; MOLECULAR EVOLUTION; NONHUMAN; PHYLOGENETIC TREE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA VIRUS; VERO CELL LINE; VIRUS MUTATION; VIRUS STRAIN; AEDES; ANIMAL; CHIKUNGUNYA; CHIKUNGUNYA VIRUS; CLASSIFICATION; DISEASE CARRIER; FEMALE; GENETICS; HUMAN; MOLECULAR GENETICS; MOUSE; PHYLOGENY; PHYSIOLOGY; TRANSMISSION; VIROLOGY;

AEDES; ANIMALS; CHIKUNGUNYA FEVER; CHIKUNGUNYA VIRUS; EVOLUTION, MOLECULAR; FEMALE; HUMANS; INSECT VECTORS; MICE; MOLECULAR SEQUENCE DATA; PHYLOGENY; VIRAL ENVELOPE PROTEINS;

EID: 84902436384     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5084     Document Type: Article

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