-
1
-
-
0018868515
-
Amyloid deposits and amyloidosis: The β-fibrilloses (second of two parts)
-
Glenner, G. G. (1980) Amyloid deposits and amyloidosis: the β-fibrilloses (second of two parts). N. Engl. J. Med. 302, 1333-1343
-
(1980)
N. Engl. J. Med.
, vol.302
, pp. 1333-1343
-
-
Glenner, G.G.1
-
2
-
-
77957880305
-
Transthyretin-related familial amyloidotic polyneuropath-Progress in Kumamoto, Japan (1967-2010)
-
Araki, S., and Ando, Y. (2010) Transthyretin-related familial amyloidotic polyneuropath-Progress in Kumamoto, Japan (1967-2010). Proc. Jpn. Acad. Ser. B Phys. Biol. Sci. 86, 694-706
-
(2010)
Proc. Jpn. Acad. Ser. B Phys. Biol. Sci.
, vol.86
, pp. 694-706
-
-
Araki, S.1
Ando, Y.2
-
3
-
-
84907416004
-
Recent advances in transthyretin amyloidosis therapy
-
Ueda, M., and Ando, Y. (2014) Recent advances in transthyretin amyloidosis therapy. Transl. Neurodegener. 3, 19
-
(2014)
Transl. Neurodegener.
, vol.3
, pp. 19
-
-
Ueda, M.1
Ando, Y.2
-
4
-
-
22844447647
-
Transthyretin-related familial amyloidotic polyneuropathy
-
Ando, Y., Nakamura, M., and Araki, S. (2005) Transthyretin-related familial amyloidotic polyneuropathy. Arch. Neurol. 62, 1057-1062
-
(2005)
Arch. Neurol.
, vol.62
, pp. 1057-1062
-
-
Ando, Y.1
Nakamura, M.2
Araki, S.3
-
5
-
-
33947245436
-
Transthyretin and familial amyloidotic polyneuropathy. Recent progress in understanding the molecular mechanism of neurodegeneration
-
Hou, X., Aguilar, M. I., and Small, D. H. (2007) Transthyretin and familial amyloidotic polyneuropathy. Recent progress in understanding the molecular mechanism of neurodegeneration. FEBS J. 274, 1637-1650
-
(2007)
FEBS J.
, vol.274
, pp. 1637-1650
-
-
Hou, X.1
Aguilar, M.I.2
Small, D.H.3
-
6
-
-
0035949432
-
An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured
-
Jiang, X., Smith, C. S., Petrassi, H. M., Hammarström, P., White, J. T., Sacchettini, J. C., and Kelly, J. W. (2001) An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured. Biochemistry 40, 11442-11452
-
(2001)
Biochemistry
, vol.40
, pp. 11442-11452
-
-
Jiang, X.1
Smith, C.S.2
Petrassi, H.M.3
Hammarström, P.4
White, J.T.5
Sacchettini, J.C.6
Kelly, J.W.7
-
7
-
-
14944368141
-
Kinetic stabilization of the native state by protein engineering: Implications for inhibition of transthyretin amyloidogenesis
-
Foss, T. R., Kelker, M. S., Wiseman, R. L., Wilson, I. A., and Kelly, J. W. (2005) Kinetic stabilization of the native state by protein engineering: implications for inhibition of transthyretin amyloidogenesis. J. Mol. Biol. 347, 841-854
-
(2005)
J. Mol. Biol.
, vol.347
, pp. 841-854
-
-
Foss, T.R.1
Kelker, M.S.2
Wiseman, R.L.3
Wilson, I.A.4
Kelly, J.W.5
-
8
-
-
2942593931
-
Transthyretin aggregation under partially denaturing conditions is a downhill polymerization
-
Hurshman, A. R., White, J. T., Powers, E. T., and Kelly, J. W. (2004) Transthyretin aggregation under partially denaturing conditions is a downhill polymerization. Biochemistry 43, 7365-7381
-
(2004)
Biochemistry
, vol.43
, pp. 7365-7381
-
-
Hurshman, A.R.1
White, J.T.2
Powers, E.T.3
Kelly, J.W.4
-
9
-
-
0029851464
-
De novo amyloid synthesis in ocular tissue in familial amyloidotic polyneuropathy after liver transplantation
-
Ando, Y., Ando, E., Tanaka, Y., Yamashita, T., Tashima, K., Suga, M., Uchino, M., Negi, A., and Ando, M. (1996) De novo amyloid synthesis in ocular tissue in familial amyloidotic polyneuropathy after liver transplantation. Transplantation 62, 1037-1038
-
(1996)
Transplantation
, vol.62
, pp. 1037-1038
-
-
Ando, Y.1
Ando, E.2
Tanaka, Y.3
Yamashita, T.4
Tashima, K.5
Suga, M.6
Uchino, M.7
Negi, A.8
Ando, M.9
-
11
-
-
84857710168
-
Tafamidis
-
Said, G., Grippon, S., and Kirkpatrick, P. (2012) Tafamidis. Nat. Rev. Drug Discov. 11, 185-186
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 185-186
-
-
Said, G.1
Grippon, S.2
Kirkpatrick, P.3
-
12
-
-
84883118140
-
Safety and efficacy of RNAi therapy for transthyretin amyloidosis
-
Coelho, T., Adams, D., Silva, A., Lozeron, P., Hawkins, P. N., Mant, T., Perez, J., Chiesa, J., Warrington, S., Tranter, E., Munisamy, M., Falzone, R., Harrop, J., Cehelsky, J., Bettencourt, B. R., et al. (2013) Safety and efficacy of RNAi therapy for transthyretin amyloidosis. N. Engl. J. Med. 369, 819-829
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 819-829
-
-
Coelho, T.1
Adams, D.2
Silva, A.3
Lozeron, P.4
Hawkins, P.N.5
Mant, T.6
Perez, J.7
Chiesa, J.8
Warrington, S.9
Tranter, E.10
Munisamy, M.11
Falzone, R.12
Harrop, J.13
Cehelsky, J.14
Bettencourt, B.R.15
-
13
-
-
0033053678
-
Exposure of cryptic epitopes on transthyretin only in amyloid and in amyloidogenic mutants
-
Goldsteins, G., Persson, H., Andersson, K., Olofsson, A., Dacklin, I., Edvinsson, A., Saraiva, M. J., and Lundgren, E. (1999) Exposure of cryptic epitopes on transthyretin only in amyloid and in amyloidogenic mutants. Proc. Natl. Acad. Sci. U.S.A. 96, 3108-3113
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 3108-3113
-
-
Goldsteins, G.1
Persson, H.2
Andersson, K.3
Olofsson, A.4
Dacklin, I.5
Edvinsson, A.6
Saraiva, M.J.7
Lundgren, E.8
-
14
-
-
0030971508
-
Analysis of amyloid deposition in a transgenic mouse model of homozygous familial amyloidotic polyneuropathy
-
Kohno, K., Palha, J. A., Miyakawa, K., Saraiva, M. J., Ito, S., Mabuchi, T., Blaner, W. S., Iijima, H., Tsukahara, S., Episkopou, V., Gottesman, M. E., Shimada, K., Takahashi, K., Yamamura, K., and Maeda, S. (1997) Analysis of amyloid deposition in a transgenic mouse model of homozygous familial amyloidotic polyneuropathy. Am. J. Pathol. 150, 1497-1508
-
(1997)
Am. J. Pathol.
, vol.150
, pp. 1497-1508
-
-
Kohno, K.1
Palha, J.A.2
Miyakawa, K.3
Saraiva, M.J.4
Ito, S.5
Mabuchi, T.6
Blaner, W.S.7
Iijima, H.8
Tsukahara, S.9
Episkopou, V.10
Gottesman, M.E.11
Shimada, K.12
Takahashi, K.13
Yamamura, K.14
Maeda, S.15
-
15
-
-
32844473029
-
Immunization in familial amyloidotic polyneuropathy: Counteracting deposition by immunization with a Y78F TTR mutant
-
Terazaki, H., Ando, Y., Fernandes, R., Yamamura, K., Maeda, S., and Saraiva, M. J. (2006) Immunization in familial amyloidotic polyneuropathy: counteracting deposition by immunization with a Y78F TTR mutant. Lab. Invest. 86, 23-31
-
(2006)
Lab. Invest.
, vol.86
, pp. 23-31
-
-
Terazaki, H.1
Ando, Y.2
Fernandes, R.3
Yamamura, K.4
Maeda, S.5
Saraiva, M.J.6
-
16
-
-
0028260652
-
Mechanisms of transthyretin amyloidogenesis. Antigenic mapping of transthyretin purified from plasma and amyloid fibrils and within in situ tissue localizations
-
Gustavsson, A., Engström, U., and Westermark, P. (1994) Mechanisms of transthyretin amyloidogenesis. Antigenic mapping of transthyretin purified from plasma and amyloid fibrils and within in situ tissue localizations. Am. J. Pathol. 144, 1301-1311
-
(1994)
Am. J. Pathol.
, vol.144
, pp. 1301-1311
-
-
Gustavsson, A.1
Engström, U.2
Westermark, P.3
-
17
-
-
0037027338
-
Disulfide-bond formation in the transthyretin mutant Y114C prevents amyloid fibril formation in vivo and in vitro
-
Eneqvist, T., Olofsson, A., Ando, Y., Miyakawa, T., Katsuragi, S., Jass, J., Lundgren, E., and Sauer-Eriksson, A. E. (2002) Disulfide-bond formation in the transthyretin mutant Y114C prevents amyloid fibril formation in vivo and in vitro. Biochemistry 41, 13143-13151
-
(2002)
Biochemistry
, vol.41
, pp. 13143-13151
-
-
Eneqvist, T.1
Olofsson, A.2
Ando, Y.3
Miyakawa, T.4
Katsuragi, S.5
Jass, J.6
Lundgren, E.7
Sauer-Eriksson, A.E.8
-
18
-
-
33746927899
-
Surface exposed epitopes and structural heterogeneity of in vivo formed transthyretin amyloid fibrils
-
Bergström, J., Engström, U., Yamashita, T., Ando, Y., and Westermark, P. (2006) Surface exposed epitopes and structural heterogeneity of in vivo formed transthyretin amyloid fibrils. Biochem. Biophys. Res. Commun. 348, 532-539
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.348
, pp. 532-539
-
-
Bergström, J.1
Engström, U.2
Yamashita, T.3
Ando, Y.4
Westermark, P.5
-
19
-
-
33751555917
-
A transgenic rat with the human ATTR V30M: A novel tool for analyses of ATTR metabolisms
-
Ueda, M., Ando, Y., Hakamata, Y., Nakamura, M., Yamashita, T., Obayashi, K., Himeno, S., Inoue, S., Sato, Y., Kaneko, T., Takamune, N., Misumi, S., Shoji, S., Uchino, M., and Kobayashi, E. (2007) A transgenic rat with the human ATTR V30M: a novel tool for analyses of ATTR metabolisms. Biochem. Biophys. Res. Commun. 352, 299-304
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.352
, pp. 299-304
-
-
Ueda, M.1
Ando, Y.2
Hakamata, Y.3
Nakamura, M.4
Yamashita, T.5
Obayashi, K.6
Himeno, S.7
Inoue, S.8
Sato, Y.9
Kaneko, T.10
Takamune, N.11
Misumi, S.12
Shoji, S.13
Uchino, M.14
Kobayashi, E.15
-
20
-
-
84861444429
-
Antibody therapy for familial amyloidotic polyneuropathy
-
Su, Y., Jono, H., Torikai, M., Hosoi, A., Soejima, K., Guo, J., Tasaki, M., Misumi, Y., Ueda, M., Shinriki, S., Shono, M., Obayashi, K., Nakashima, T., Sugawara, K., and Ando, Y. (2012) Antibody therapy for familial amyloidotic polyneuropathy. Amyloid 19, 45-46
-
(2012)
Amyloid
, vol.19
, pp. 45-46
-
-
Su, Y.1
Jono, H.2
Torikai, M.3
Hosoi, A.4
Soejima, K.5
Guo, J.6
Tasaki, M.7
Misumi, Y.8
Ueda, M.9
Shinriki, S.10
Shono, M.11
Obayashi, K.12
Nakashima, T.13
Sugawara, K.14
Ando, Y.15
-
21
-
-
84899000210
-
Transthyretin aggregate-specific antibodies recognize cryptic epitopes on patient-derived amyloid fibrils
-
Phay, M., Blinder, V., Macy, S., Greene, M. J., Wooliver, D. C., Liu, W., Planas, A., Walsh, D. M., Connors, L. H., Primmer, S. R., Planque, S. A., Paul, S., and O'Nuallain, B. (2014) Transthyretin aggregate-specific antibodies recognize cryptic epitopes on patient-derived amyloid fibrils. Rejuvenation Res. 17, 97-104
-
(2014)
Rejuvenation Res.
, vol.17
, pp. 97-104
-
-
Phay, M.1
Blinder, V.2
Macy, S.3
Greene, M.J.4
Wooliver, D.C.5
Liu, W.6
Planas, A.7
Walsh, D.M.8
Connors, L.H.9
Primmer, S.R.10
Planque, S.A.11
Paul, S.12
O'Nuallain, B.13
-
22
-
-
84925279976
-
Immunotherapeutic approaches for Alzheimer's disease
-
Wisniewski, T., and Goñi, F. (2015) Immunotherapeutic approaches for Alzheimer's disease. Neuron 85, 1162-1176
-
(2015)
Neuron
, vol.85
, pp. 1162-1176
-
-
Wisniewski, T.1
Goñi, F.2
-
23
-
-
84895729926
-
Amyloid-β-directed immunotherapy for Alzheimer's disease
-
Lannfelt, L., Relkin, N. R., and Siemers, E. R. (2014) Amyloid-β-directed immunotherapy for Alzheimer's disease. J. Intern. Med. 275, 284-295
-
(2014)
J. Intern. Med.
, vol.275
, pp. 284-295
-
-
Lannfelt, L.1
Relkin, N.R.2
Siemers, E.R.3
-
24
-
-
84860697106
-
Methods to evaluate the inhibition of TTR fibrillogenesis induced by small ligands
-
Arsequell, G., and Planas, A. (2012) Methods to evaluate the inhibition of TTR fibrillogenesis induced by small ligands. Curr. Med. Chem. 19, 2343-2355
-
(2012)
Curr. Med. Chem.
, vol.19
, pp. 2343-2355
-
-
Arsequell, G.1
Planas, A.2
-
25
-
-
0038348204
-
Expression of a synthetic gene encoding human transthyretin in Escherichia coli
-
Matsubara, K., Mizuguchi, M., and Kawano, K. (2003) Expression of a synthetic gene encoding human transthyretin in Escherichia coli. Protein Expr. Purif. 30, 55-61
-
(2003)
Protein Expr. Purif.
, vol.30
, pp. 55-61
-
-
Matsubara, K.1
Mizuguchi, M.2
Kawano, K.3
-
26
-
-
0027512354
-
Disruption of the transthyretin gene results in mice with depressed levels of plasma retinol and thyroid hormone
-
Episkopou, V., Maeda, S., Nishiguchi, S., Shimada, K., Gaitanaris, G. A., Gottesman, M. E., and Robertson, E. J. (1993) Disruption of the transthyretin gene results in mice with depressed levels of plasma retinol and thyroid hormone. Proc. Natl. Acad. Sci. U.S.A. 90, 2375-2379
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 2375-2379
-
-
Episkopou, V.1
Maeda, S.2
Nishiguchi, S.3
Shimada, K.4
Gaitanaris, G.A.5
Gottesman, M.E.6
Robertson, E.J.7
-
27
-
-
0016756272
-
Continuous cultures of fused cells secreting antibody of predefined specificity
-
Köhler, G., and Milstein, C. (1975) Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256, 495-497
-
(1975)
Nature
, vol.256
, pp. 495-497
-
-
Köhler, G.1
Milstein, C.2
-
28
-
-
3042709224
-
Preparation of recombinant α-thrombin: High-level expression of recombinant human prethrombin-2 and its activation by recombinant ecarin
-
Yonemura, H., Imamura, T., Soejima, K., Nakahara, Y., Morikawa, W., Ushio, Y., Kamachi, Y., Nakatake, H., Sugawara, K., Nakagaki, T., and Nozaki, C. (2004) Preparation of recombinant α-thrombin: high-level expression of recombinant human prethrombin-2 and its activation by recombinant ecarin. J. Biochem. 135, 577-582
-
(2004)
J. Biochem.
, vol.135
, pp. 577-582
-
-
Yonemura, H.1
Imamura, T.2
Soejima, K.3
Nakahara, Y.4
Morikawa, W.5
Ushio, Y.6
Kamachi, Y.7
Nakatake, H.8
Sugawara, K.9
Nakagaki, T.10
Nozaki, C.11
-
29
-
-
0026559783
-
Antibody framework residues affecting the conformation of the hypervariable loops
-
Foote, J., and Winter, G. (1992) Antibody framework residues affecting the conformation of the hypervariable loops. J. Mol. Biol. 224, 487-499
-
(1992)
J. Mol. Biol.
, vol.224
, pp. 487-499
-
-
Foote, J.1
Winter, G.2
-
30
-
-
0025978976
-
Man-made antibodies
-
Winter, G., and Milstein, C. (1991) Man-made antibodies. Nature 349, 293-299
-
(1991)
Nature
, vol.349
, pp. 293-299
-
-
Winter, G.1
Milstein, C.2
-
31
-
-
25144489633
-
Mechanism of thioflavin T binding to amyloid fibrils
-
Khurana, R., Coleman, C., Ionescu-Zanetti, C., Carter, S. A., Krishna, V., Grover, R. K., Roy, R., and Singh, S. (2005) Mechanism of thioflavin T binding to amyloid fibrils. J. Struct. Biol. 151, 229-238
-
(2005)
J. Struct. Biol.
, vol.151
, pp. 229-238
-
-
Khurana, R.1
Coleman, C.2
Ionescu-Zanetti, C.3
Carter, S.A.4
Krishna, V.5
Grover, R.K.6
Roy, R.7
Singh, S.8
-
32
-
-
84877749893
-
TAP-deficient human iPS cell-derived myeloid cell lines as unlimited cell source for dendritic cell-like antigen-presenting cells
-
Haruta, M., Tomita, Y., Yuno, A., Matsumura, K., Ikeda, T., Takamatsu, K., Haga, E., Koba, C., Nishimura, Y., and Senju, S. (2013) TAP-deficient human iPS cell-derived myeloid cell lines as unlimited cell source for dendritic cell-like antigen-presenting cells. Gene Ther. 20, 504-513
-
(2013)
Gene Ther.
, vol.20
, pp. 504-513
-
-
Haruta, M.1
Tomita, Y.2
Yuno, A.3
Matsumura, K.4
Ikeda, T.5
Takamatsu, K.6
Haga, E.7
Koba, C.8
Nishimura, Y.9
Senju, S.10
-
33
-
-
33750985079
-
FK506 inhibits murine AA amyloidosis: Possible involvement of T cells in amyloidogenesis
-
Ueda, M., Ando, Y., Nakamura, M., Yamashita, T., Himeno, S., Kim, J., Sun, X., Saito, S., Tateishi, T., Bergström, J., and Uchino, M. (2006) FK506 inhibits murine AA amyloidosis: possible involvement of T cells in amyloidogenesis. J. Rheumatol. 33, 2260-2270
-
(2006)
J. Rheumatol.
, vol.33
, pp. 2260-2270
-
-
Ueda, M.1
Ando, Y.2
Nakamura, M.3
Yamashita, T.4
Himeno, S.5
Kim, J.6
Sun, X.7
Saito, S.8
Tateishi, T.9
Bergström, J.10
Uchino, M.11
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