메뉴 건너뛰기




Volumn 3, Issue 5, 2013, Pages 278-293

Possible mechanisms for the skeletal effects of antipsychotics in children and adolescents

Author keywords

antipsychotics; bone metabolism; hyperprolactinemia; osteoporosis; psychopathology; skeletal development

Indexed keywords


EID: 84997907195     PISSN: 20451253     EISSN: 20451261     Source Type: Journal    
DOI: 10.1177/2045125313487548     Document Type: Article
Times cited : (35)

References (121)
  • 1
    • 0642343895 scopus 로고    scopus 로고
    • Effects of elevated serum prolactin on bone mineral density and bone metabolism in female patients with schizophrenia: a prospective study
    • Abraham G. Paing W. Kaminski J. Joseph A. Kohegyi E. Josiassen R. (2003) Effects of elevated serum prolactin on bone mineral density and bone metabolism in female patients with schizophrenia: a prospective study. Am J Psychiatry 160: 1618–1620.
    • (2003) Am J Psychiatry , vol.160 , pp. 1618-1620
    • Abraham, G.1    Paing, W.2    Kaminski, J.3    Joseph, A.4    Kohegyi, E.5    Josiassen, R.6
  • 2
    • 33846562907 scopus 로고    scopus 로고
    • Effects of short- and long-term risperidone treatment on prolactin levels in children with autism
    • Anderson G. Scahill L. McCracken J. McDougle C. Aman M. Tierney E. et al. (2007) Effects of short- and long-term risperidone treatment on prolactin levels in children with autism. Biol Psychiatry 61: 545–550.
    • (2007) Biol Psychiatry , vol.61 , pp. 545-550
    • Anderson, G.1    Scahill, L.2    McCracken, J.3    McDougle, C.4    Aman, M.5    Tierney, E.6
  • 3
    • 78650776090 scopus 로고    scopus 로고
    • Clinical report-bone densitometry in children and adolescents
    • Bachrach L. Sills I. (2011) Clinical report-bone densitometry in children and adolescents. Pediatrics 127: 189–194.
    • (2011) Pediatrics , vol.127 , pp. 189-194
    • Bachrach, L.1    Sills, I.2
  • 4
    • 42649117795 scopus 로고    scopus 로고
    • Official positions of the International Society for Clinical Densitometry and executive summary of the 2007 ISCD Pediatric Position Development Conference
    • Baim S. Leonard M. Bianchi M. Hans D. Kalkwarf H. Langman C. et al. (2008) Official positions of the International Society for Clinical Densitometry and executive summary of the 2007 ISCD Pediatric Position Development Conference. J Clin Densitom 11: 6–21.
    • (2008) J Clin Densitom , vol.11 , pp. 6-21
    • Baim, S.1    Leonard, M.2    Bianchi, M.3    Hans, D.4    Kalkwarf, H.5    Langman, C.6
  • 5
    • 0021988615 scopus 로고
    • Increased hepatic and reduced prostatic prolactin (PRL) binding in iron deficiency and during neuroleptic treatment: correlation with changes in serum PRL and testosterone
    • Barkey R. Ben-Shachar D. Amit T. Youdim M. (1985) Increased hepatic and reduced prostatic prolactin (PRL) binding in iron deficiency and during neuroleptic treatment: correlation with changes in serum PRL and testosterone. Eur J Pharmacol 109: 193–200.
    • (1985) Eur J Pharmacol , vol.109 , pp. 193-200
    • Barkey, R.1    Ben-Shachar, D.2    Amit, T.3    Youdim, M.4
  • 6
    • 77956198308 scopus 로고    scopus 로고
    • Serotonergic 5-HT(2b) receptor controls tissue-nonspecific alkaline phosphatase activity in osteoblasts via eicosanoids and phosphatidylinositol-specific phospholipase C
    • Baudry A. Bitard J. Mouillet-Richard S. Locker M. Poliard A. Launay J. et al. (2010) Serotonergic 5-HT(2b) receptor controls tissue-nonspecific alkaline phosphatase activity in osteoblasts via eicosanoids and phosphatidylinositol-specific phospholipase C. J Biol Chem 285: 26066–26073.
    • (2010) J Biol Chem , vol.285 , pp. 26066-26073
    • Baudry, A.1    Bitard, J.2    Mouillet-Richard, S.3    Locker, M.4    Poliard, A.5    Launay, J.6
  • 7
    • 0041304618 scopus 로고    scopus 로고
    • Risperidone, but not olanzapine, decreases bone mineral density in female premenopausal schizophrenia patients
    • Becker D. Liver O. Mester R. Rapoport M. Weizman A. Weiss M. (2003) Risperidone, but not olanzapine, decreases bone mineral density in female premenopausal schizophrenia patients. J Clin Psychiatry 64: 761–766.
    • (2003) J Clin Psychiatry , vol.64 , pp. 761-766
    • Becker, D.1    Liver, O.2    Mester, R.3    Rapoport, M.4    Weizman, A.5    Weiss, M.6
  • 8
    • 0035986765 scopus 로고    scopus 로고
    • Classical and atypical neuroleptics, and bone mineral density, in patients with schizophrenia
    • Bilici M. Cakirbay H. Guler M. Tosun M. Ulgen M. Tan U. (2002) Classical and atypical neuroleptics, and bone mineral density, in patients with schizophrenia. Int J Neurosci 112: 817–828.
    • (2002) Int J Neurosci , vol.112 , pp. 817-828
    • Bilici, M.1    Cakirbay, H.2    Guler, M.3    Tosun, M.4    Ulgen, M.5    Tan, U.6
  • 10
    • 0034747779 scopus 로고    scopus 로고
    • Neurotransmitter action in osteoblasts: expression of a functional system for serotonin receptor activation and reuptake
    • Bliziotes M. Eshleman A. Zhang X. Wiren K. (2001) Neurotransmitter action in osteoblasts: expression of a functional system for serotonin receptor activation and reuptake. Bone 29: 477–486.
    • (2001) Bone , vol.29 , pp. 477-486
    • Bliziotes, M.1    Eshleman, A.2    Zhang, X.3    Wiren, K.4
  • 11
    • 0033522430 scopus 로고    scopus 로고
    • Antagonism by olanzapine of dopamine D1, serotonin2, muscarinic, histamine H1 and alpha 1-adrenergic receptors in vitro
    • Bymaster F. Nelson D. DeLapp N. Falcone J. Eckols K. Truex L. et al. (1999) Antagonism by olanzapine of dopamine D1, serotonin2, muscarinic, histamine H1 and alpha 1-adrenergic receptors in vitro. Schizophrenia research 37: 107–122.
    • (1999) Schizophrenia research , vol.37 , pp. 107-122
    • Bymaster, F.1    Nelson, D.2    DeLapp, N.3    Falcone, J.4    Eckols, K.5    Truex, L.6
  • 12
    • 65249112709 scopus 로고    scopus 로고
    • Weight gain and metabolic abnormalities during extended risperidone treatment in children and adolescents
    • Calarge C. Acion L. Kuperman S. Tansey M. Schlechte J. (2009a) Weight gain and metabolic abnormalities during extended risperidone treatment in children and adolescents. J Child Adolesc Psychopharmacol 19: 101–109.
    • (2009) J Child Adolesc Psychopharmacol , vol.19 , pp. 101-109
    • Calarge, C.1    Acion, L.2    Kuperman, S.3    Tansey, M.4    Schlechte, J.5
  • 13
    • 67149131622 scopus 로고    scopus 로고
    • Variants of the dopamine D2 receptor gene and risperidone-induced hyperprolactinemia in children and adolescents
    • Calarge C. Ellingrod V. Acion L. Miller D. Moline J. Tansey M. et al. (2009b) Variants of the dopamine D2 receptor gene and risperidone-induced hyperprolactinemia in children and adolescents. Pharmacogenet Genomics 19: 373–382.
    • (2009) Pharmacogenet Genomics , vol.19 , pp. 373-382
    • Calarge, C.1    Ellingrod, V.2    Acion, L.3    Miller, D.4    Moline, J.5    Tansey, M.6
  • 14
    • 84555220533 scopus 로고    scopus 로고
    • Variants of the serotonin transporter gene, selective serotonin reuptake inhibitors, and bone mineral density in risperidone-treated boys: a reanalysis of data from a cross-sectional study with emphasis on pharmacogenetics
    • Calarge C. Ellingrod V. Zimmerman B. Bliziotes M. Schlechte J. (2011) Variants of the serotonin transporter gene, selective serotonin reuptake inhibitors, and bone mineral density in risperidone-treated boys: a reanalysis of data from a cross-sectional study with emphasis on pharmacogenetics. J Clin Psychiatry 72: 1685–1690.
    • (2011) J Clin Psychiatry , vol.72 , pp. 1685-1690
    • Calarge, C.1    Ellingrod, V.2    Zimmerman, B.3    Bliziotes, M.4    Schlechte, J.5
  • 15
    • 84875460996 scopus 로고    scopus 로고
    • Iron deficiency in pediatric patients in long-term risperidone treatment
    • Calarge C. Ziegler E. (2013) Iron deficiency in pediatric patients in long-term risperidone treatment. J Child Adolesc Psychopharmacol 23: 101–109.
    • (2013) J Child Adolesc Psychopharmacol , vol.23 , pp. 101-109
    • Calarge, C.1    Ziegler, E.2
  • 16
    • 77950302945 scopus 로고    scopus 로고
    • A cross-sectional evaluation of the effect of risperidone and selective serotonin reuptake inhibitors on bone mineral density in boys
    • Calarge C. Zimmerman B. Xie D. Kuperman S. Schlechte J. (2010) A cross-sectional evaluation of the effect of risperidone and selective serotonin reuptake inhibitors on bone mineral density in boys. J Clin Psychiatry 71: 338–347.
    • (2010) J Clin Psychiatry , vol.71 , pp. 338-347
    • Calarge, C.1    Zimmerman, B.2    Xie, D.3    Kuperman, S.4    Schlechte, J.5
  • 18
    • 0034877966 scopus 로고    scopus 로고
    • Prolactin directly stimulates transcellular active calcium transport in the duodenum of female rats
    • Charoenphandhu N. Limlomwongse L. Krishnamra N. (2001) Prolactin directly stimulates transcellular active calcium transport in the duodenum of female rats. Can J Physiol Pharmacol 79: 430–438.
    • (2001) Can J Physiol Pharmacol , vol.79 , pp. 430-438
    • Charoenphandhu, N.1    Limlomwongse, L.2    Krishnamra, N.3
  • 20
    • 0013577437 scopus 로고    scopus 로고
    • Osteoblasts are a new target for prolactin: analysis of bone formation in prolactin receptor knockout mice
    • Clement-Lacroix P. Ormandy C. Lepescheux L. Ammann P. Damotte D. Goffin V. et al. (1999) Osteoblasts are a new target for prolactin: analysis of bone formation in prolactin receptor knockout mice. Endocrinology 140: 96–105.
    • (1999) Endocrinology , vol.140 , pp. 96-105
    • Clement-Lacroix, P.1    Ormandy, C.2    Lepescheux, L.3    Ammann, P.4    Damotte, D.5    Goffin, V.6
  • 21
    • 0034073803 scopus 로고    scopus 로고
    • Prolactinomas in adolescents: persistent bone loss after 2 years of prolactin normalization
    • Colao A. Di Somma C. Loche S. Di Sarno A. Klain M. Pivonello R. et al. (2000) Prolactinomas in adolescents: persistent bone loss after 2 years of prolactin normalization. Clin Endocrinol (Oxf) 52: 319–327.
    • (2000) Clin Endocrinol (Oxf) , vol.52 , pp. 319-327
    • Colao, A.1    Di Somma, C.2    Loche, S.3    Di Sarno, A.4    Klain, M.5    Pivonello, R.6
  • 22
  • 23
    • 38949152272 scopus 로고    scopus 로고
    • The serotonin 5-HT2b receptor controls bone mass via osteoblast recruitment and proliferation
    • Collet C. Schiltz C. Geoffroy V. Maroteaux L. Launay J. de Vernejoul M. (2008) The serotonin 5-HT2b receptor controls bone mass via osteoblast recruitment and proliferation. FASEB J 22: 418–427.
    • (2008) FASEB J , vol.22 , pp. 418-427
    • Collet, C.1    Schiltz, C.2    Geoffroy, V.3    Maroteaux, L.4    Launay, J.5    de Vernejoul, M.6
  • 24
    • 77956961015 scopus 로고    scopus 로고
    • National trends in child and adolescent psychotropic polypharmacy in office-based practice, 1996–2007
    • Comer J. Olfson M. Mojtabai R. (2010) National trends in child and adolescent psychotropic polypharmacy in office-based practice, 1996–2007. J Am Acad Child Adolesc Psychiatry 49: 1001–1010.
    • (2010) J Am Acad Child Adolesc Psychiatry , vol.49 , pp. 1001-1010
    • Comer, J.1    Olfson, M.2    Mojtabai, R.3
  • 26
    • 33745301687 scopus 로고    scopus 로고
    • Endocrine and metabolic adverse effects of psychotropic medications in children and adolescents
    • Correll C. Carlson H. (2006) Endocrine and metabolic adverse effects of psychotropic medications in children and adolescents. J Am Acad Child Adolesc Psychiatry 45: 771–791.
    • (2006) J Am Acad Child Adolesc Psychiatry , vol.45 , pp. 771-791
    • Correll, C.1    Carlson, H.2
  • 27
    • 70350738289 scopus 로고    scopus 로고
    • Cardiometabolic risk of second-generation antipsychotic medications during first-time use in children and adolescents
    • Correll C. Manu P. Olshanskiy V. Napolitano B. Kane J. Malhotra A. (2009) Cardiometabolic risk of second-generation antipsychotic medications during first-time use in children and adolescents. JAMA 302: 1765–1773.
    • (2009) JAMA , vol.302 , pp. 1765-1773
    • Correll, C.1    Manu, P.2    Olshanskiy, V.3    Napolitano, B.4    Kane, J.5    Malhotra, A.6
  • 28
    • 0033635911 scopus 로고    scopus 로고
    • Effects of prolactin on osteoblast alkaline phosphatase and bone formation in the developing rat
    • Coss D. Yang L. Kuo C. Xu X. Luben R. Walker A. (2000) Effects of prolactin on osteoblast alkaline phosphatase and bone formation in the developing rat. Am J Physiol Endocrinol Metab 279: E1216–E1225.
    • (2000) Am J Physiol Endocrinol Metab , vol.279 , pp. E1216-E1225
    • Coss, D.1    Yang, L.2    Kuo, C.3    Xu, X.4    Luben, R.5    Walker, A.6
  • 29
    • 79952006593 scopus 로고    scopus 로고
    • The atypical anti-psychotic clozapine decreases bone mass in rats in vivo
    • Costa J. Smith G. Watson M. Lin J. Callon K. Gamble G. et al. (2011) The atypical anti-psychotic clozapine decreases bone mass in rats in vivo. Schizophr Res 126: 291–297.
    • (2011) Schizophr Res , vol.126 , pp. 291-297
    • Costa, J.1    Smith, G.2    Watson, M.3    Lin, J.4    Callon, K.5    Gamble, G.6
  • 30
    • 70349202409 scopus 로고    scopus 로고
    • Broadened use of atypical antipsychotics: safety, effectiveness, and policy challenges
    • Crystal S. Olfson M. Huang C. Pincus H. Gerhard T. (2009) Broadened use of atypical antipsychotics: safety, effectiveness, and policy challenges. Health Aff (Millwood) 28: w770–w781.
    • (2009) Health Aff (Millwood) , vol.28 , pp. w770-w781
    • Crystal, S.1    Olfson, M.2    Huang, C.3    Pincus, H.4    Gerhard, T.5
  • 32
    • 79953694768 scopus 로고    scopus 로고
    • 5-HT and bone biology
    • Ducy P. (2011) 5-HT and bone biology. Curr Opin Pharmacol 11: 34–38.
    • (2011) Curr Opin Pharmacol , vol.11 , pp. 34-38
    • Ducy, P.1
  • 34
    • 2442623366 scopus 로고    scopus 로고
    • Growth and sexual maturation during long-term treatment with risperidone
    • Dunbar F. Kusumakar V. Daneman D. Schulz M. (2004) Growth and sexual maturation during long-term treatment with risperidone. Am J Psychiatry 161: 918–920.
    • (2004) Am J Psychiatry , vol.161 , pp. 918-920
    • Dunbar, F.1    Kusumakar, V.2    Daneman, D.3    Schulz, M.4
  • 35
    • 0035187142 scopus 로고    scopus 로고
    • Prolactinomas in children and adolescents – consequences in adult life
    • discussion 1261–1222
    • Duntas L. (2001) Prolactinomas in children and adolescents – consequences in adult life. J Pediatr Endocrinol Metab 14(Suppl 5): 1227–1232; discussion 1261–1222.
    • (2001) J Pediatr Endocrinol Metab , vol.14 , pp. 1227-1232
    • Duntas, L.1
  • 40
    • 84998117823 scopus 로고    scopus 로고
    • Seroquel® (quetiapine fumarate) tablets for the treatment of pediatric patients with schizophrenia (13-17 years old) or bipolar mania (10–17 years old)
    • 9–10 June, 2009, Available at
    • FDA (2009) Seroquel® (quetiapine fumarate) tablets for the treatment of pediatric patients with schizophrenia (13-17 years old) or bipolar mania (10–17 years old). Briefing document for Psychopharmacologic Drugs Advisory Committee Meeting, 9–10 June 2009. Available at: http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/PsychopharmacologicDrugsAdvisoryCommittee/UCM164280.pdf
    • (2009) Briefing document for Psychopharmacologic Drugs Advisory Committee Meeting
  • 41
    • 77952319138 scopus 로고    scopus 로고
    • Double-blind maintenance safety and effectiveness findings from the Treatment of Early-Onset Schizophrenia Spectrum (TEOSS) study
    • quiz 632
    • Findling R. Johnson J. McClellan J. Frazier J. Vitiello B. Hamer R. et al. (2010) Double-blind maintenance safety and effectiveness findings from the Treatment of Early-Onset Schizophrenia Spectrum (TEOSS) study. J Am Acad Child Adolesc Psychiatry 49: 583–594; quiz 632.
    • (2010) J Am Acad Child Adolesc Psychiatry , vol.49 , pp. 583-594
    • Findling, R.1    Johnson, J.2    McClellan, J.3    Frazier, J.4    Vitiello, B.5    Hamer, R.6
  • 43
    • 55749106241 scopus 로고    scopus 로고
    • A multiple-center, randomized, double-blind, placebo-controlled study of oral aripiprazole for treatment of adolescents with schizophrenia
    • Findling R. Robb A. Nyilas M. Forbes R. Jin N. Ivanova S. et al. (2008) A multiple-center, randomized, double-blind, placebo-controlled study of oral aripiprazole for treatment of adolescents with schizophrenia. Am J Psychiatry 165: 1432–1441.
    • (2008) Am J Psychiatry , vol.165 , pp. 1432-1441
    • Findling, R.1    Robb, A.2    Nyilas, M.3    Forbes, R.4    Jin, N.5    Ivanova, S.6
  • 44
    • 33847220680 scopus 로고    scopus 로고
    • The ‘functional muscle-bone unit’: probing the relevance of mechanical signals for bone development in children and adolescents
    • Fricke O. Schoenau E. (2007) The ‘functional muscle-bone unit’: probing the relevance of mechanical signals for bone development in children and adolescents. Growth Horm IGF Res 17: 1–9.
    • (2007) Growth Horm IGF Res , vol.17 , pp. 1-9
    • Fricke, O.1    Schoenau, E.2
  • 45
    • 0023492075 scopus 로고
    • Bone ‘mass’ and the ‘mechanostat’: a proposal
    • Frost H. (1987) Bone ‘mass’ and the ‘mechanostat’: a proposal. Anat Rec 219: 1–9.
    • (1987) Anat Rec , vol.219 , pp. 1-9
    • Frost, H.1
  • 46
    • 0027536507 scopus 로고
    • Mechanism-Based Design of Prolactin Receptor Antagonists
    • Fuh G. Colosi P. Wood W.I. Wells J.A. (1993) Mechanism-Based Design of Prolactin Receptor Antagonists. J Biol Chem 268: 5376–5381.
    • (1993) J Biol Chem , vol.268 , pp. 5376-5381
    • Fuh, G.1    Colosi, P.2    Wood, W.I.3    Wells, J.A.4
  • 47
    • 84860742323 scopus 로고    scopus 로고
    • A randomized controlled trial of risperidone, lithium, or divalproex sodium for initial treatment of bipolar I disorder, manic or mixed phase, in children and adolescents
    • Geller B. Luby J. Joshi P. Wagner K. Emslie G. Walkup J. et al. (2012) A randomized controlled trial of risperidone, lithium, or divalproex sodium for initial treatment of bipolar I disorder, manic or mixed phase, in children and adolescents. Arch Gen Psychiatry 69: 515–528.
    • (2012) Arch Gen Psychiatry , vol.69 , pp. 515-528
    • Geller, B.1    Luby, J.2    Joshi, P.3    Wagner, K.4    Emslie, G.5    Walkup, J.6
  • 48
    • 0024509604 scopus 로고
    • Importance of gonadal steroids to bone mass in men with hyperprolactinemic hypogonadism
    • Greenspan S. Oppenheim D. Klibanski A. (1989) Importance of gonadal steroids to bone mass in men with hyperprolactinemic hypogonadism. Ann Intern Med 110: 526–531.
    • (1989) Ann Intern Med , vol.110 , pp. 526-531
    • Greenspan, S.1    Oppenheim, D.2    Klibanski, A.3
  • 49
    • 0037215345 scopus 로고    scopus 로고
    • Elevated prolactin levels in patients with schizophrenia: mechanisms and related adverse effects
    • Halbreich U. Kinon B. Gilmore J. Kahn L. (2003) Elevated prolactin levels in patients with schizophrenia: mechanisms and related adverse effects. Psychoneuroendocrinology 28(Suppl. 1): 53–67.
    • (2003) Psychoneuroendocrinology , vol.28 , pp. 53-67
    • Halbreich, U.1    Kinon, B.2    Gilmore, J.3    Kahn, L.4
  • 50
    • 18844458606 scopus 로고    scopus 로고
    • Bone mineral density and its relationship to prolactin levels in patients taking antipsychotic treatment
    • Howes O. Wheeler M. Meaney A. O’Keane V. Fogelman I. Blake G. et al. (2005) Bone mineral density and its relationship to prolactin levels in patients taking antipsychotic treatment. J Clin Psychopharmacol 25: 259–261.
    • (2005) J Clin Psychopharmacol , vol.25 , pp. 259-261
    • Howes, O.1    Wheeler, M.2    Meaney, A.3    O’Keane, V.4    Fogelman, I.5    Blake, G.6
  • 51
    • 65549105822 scopus 로고    scopus 로고
    • Functional alpha1- and beta2-adrenergic receptors in human osteoblasts
    • Huang H. Brennan T. Muir M. Mason R. (2009) Functional alpha1- and beta2-adrenergic receptors in human osteoblasts. J Cell Physiol 220: 267–275.
    • (2009) J Cell Physiol , vol.220 , pp. 267-275
    • Huang, H.1    Brennan, T.2    Muir, M.3    Mason, R.4
  • 52
    • 84995826606 scopus 로고
    • Receptor dimerization determines the effects of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes
    • Ilondo M. Damholt A. Cunningham B. Wells J. De Meyts P. Shymko R. (1994) Receptor dimerization determines the effects of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes. Endocrinology 134: 2397–2403.
    • (1994) Endocrinology , vol.134 , pp. 2397-2403
    • Ilondo, M.1    Damholt, A.2    Cunningham, B.3    Wells, J.4    De Meyts, P.5    Shymko, R.6
  • 53
    • 33750046617 scopus 로고    scopus 로고
    • Prevalence of bone mineral density loss in Korean patients with schizophrenia: a cross-sectional study
    • Jung D. Conley R. Kelly D. Kim D. Yoon S. Jang J. et al. (2006) Prevalence of bone mineral density loss in Korean patients with schizophrenia: a cross-sectional study. J Clin Psychiatry 67: 1391–1396.
    • (2006) J Clin Psychiatry , vol.67 , pp. 1391-1396
    • Jung, D.1    Conley, R.2    Kelly, D.3    Kim, D.4    Yoon, S.5    Jang, J.6
  • 54
    • 33646404654 scopus 로고    scopus 로고
    • The hypothalamic control of bone mass, implication for the treatment of osteoporosis
    • Karsenty G. Ducy P. (2006) The hypothalamic control of bone mass, implication for the treatment of osteoporosis. Ann Endocrinol (Paris) 67: 123.
    • (2006) Ann Endocrinol (Paris) , vol.67 , pp. 123
    • Karsenty, G.1    Ducy, P.2
  • 56
    • 42249115509 scopus 로고    scopus 로고
    • Antipsychotic-induced hyperprolactinemia inhibits the hypothalamo-pituitary-gonadal axis and reduces bone mineral density in male patients with schizophrenia
    • Kishimoto T. Watanabe K. Shimada N. Makita K. Yagi G. Kashima H. (2008) Antipsychotic-induced hyperprolactinemia inhibits the hypothalamo-pituitary-gonadal axis and reduces bone mineral density in male patients with schizophrenia. J Clin Psychiatry 69: 385–391.
    • (2008) J Clin Psychiatry , vol.69 , pp. 385-391
    • Kishimoto, T.1    Watanabe, K.2    Shimada, N.3    Makita, K.4    Yagi, G.5    Kashima, H.6
  • 58
    • 0028787969 scopus 로고
    • Hyperprolactinemia caused by lactation and pituitary adenomas is associated with altered serum calcium, phosphate, parathyroid hormone (PTH), and PTH-related peptide levels
    • Kovacs C. Chik C. (1995) Hyperprolactinemia caused by lactation and pituitary adenomas is associated with altered serum calcium, phosphate, parathyroid hormone (PTH), and PTH-related peptide levels. J Clin Endocrinol Metab 80: 3036–3042.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 3036-3042
    • Kovacs, C.1    Chik, C.2
  • 62
    • 79959506829 scopus 로고    scopus 로고
    • The antipsychotics haloperidol and chlorpromazine increase bone metabolism and induce osteopenia in female rats
    • Kunimatsu T. Kimura J. Funabashi H. Inoue T. Seki T. (2010) The antipsychotics haloperidol and chlorpromazine increase bone metabolism and induce osteopenia in female rats. Regul Toxicol Pharmacol 58: 360–368.
    • (2010) Regul Toxicol Pharmacol , vol.58 , pp. 360-368
    • Kunimatsu, T.1    Kimura, J.2    Funabashi, H.3    Inoue, T.4    Seki, T.5
  • 63
    • 0017672812 scopus 로고
    • The prolactin response to neuroleptic drugs. a test of dopaminergic blockade: neuroendocrine studies in normal men
    • Langer G. Sachar E. Halpern F. Gruen P. Solomon M. (1977) The prolactin response to neuroleptic drugs. a test of dopaminergic blockade: neuroendocrine studies in normal men. J Clin Endocrinol Metab 45: 996–1002.
    • (1977) J Clin Endocrinol Metab , vol.45 , pp. 996-1002
    • Langer, G.1    Sachar, E.2    Halpern, F.3    Gruen, P.4    Solomon, M.5
  • 64
    • 67651230394 scopus 로고    scopus 로고
    • Official positions of the International Society for Clinical Densitometry: perceptions and commentary
    • Lewiecki E. Baim S. Langman C. Bilezikian J. (2009) Official positions of the International Society for Clinical Densitometry: perceptions and commentary. J Clin Densitom 12: 267–271.
    • (2009) J Clin Densitom , vol.12 , pp. 267-271
    • Lewiecki, E.1    Baim, S.2    Langman, C.3    Bilezikian, J.4
  • 65
    • 0026562188 scopus 로고
    • In vitro and in vivo receptor binding and effects on monoamine turnover in rat brain regions of the novel antipsychotics risperidone and ocaperidone
    • Leysen J. Janssen P. Gommeren W. Wynants J. Pauwels P. Janssen P. (1992) In vitro and in vivo receptor binding and effects on monoamine turnover in rat brain regions of the novel antipsychotics risperidone and ocaperidone. Mol Pharmacol 41: 494–508.
    • (1992) Mol Pharmacol , vol.41 , pp. 494-508
    • Leysen, J.1    Janssen, P.2    Gommeren, W.3    Wynants, J.4    Pauwels, P.5    Janssen, P.6
  • 66
    • 30944443360 scopus 로고    scopus 로고
    • Stepwise control of osteogenic differentiation by 5-HT(2B) receptor signaling: nitric oxide production and phospholipase A2 activation
    • Locker M. Bitard J. Collet C. Poliard A. Mutel V. Launay J. et al. (2006) Stepwise control of osteogenic differentiation by 5-HT(2B) receptor signaling: nitric oxide production and phospholipase A2 activation. Cell Signal 18: 628–639.
    • (2006) Cell Signal , vol.18 , pp. 628-639
    • Locker, M.1    Bitard, J.2    Collet, C.3    Poliard, A.4    Mutel, V.5    Launay, J.6
  • 67
    • 0031802147 scopus 로고    scopus 로고
    • The study of a physiological significance of prolactin in the regulation of calcium metabolism during pregnancy and lactation in rats
    • Lotinun S. Limlomwongse L. Krishnamra N. (1998) The study of a physiological significance of prolactin in the regulation of calcium metabolism during pregnancy and lactation in rats. Can J Physiol Pharmacol 76: 218–228.
    • (1998) Can J Physiol Pharmacol , vol.76 , pp. 218-228
    • Lotinun, S.1    Limlomwongse, L.2    Krishnamra, N.3
  • 68
    • 0037319204 scopus 로고    scopus 로고
    • Bone calcium turnover, formation, and resorption in bromocriptine- and prolactin-treated lactating rats
    • Lotinun S. Limlomwongse L. Sirikulchayanonta V. Krishnamra N. (2003) Bone calcium turnover, formation, and resorption in bromocriptine- and prolactin-treated lactating rats. Endocrine 20: 163–170.
    • (2003) Endocrine , vol.20 , pp. 163-170
    • Lotinun, S.1    Limlomwongse, L.2    Sirikulchayanonta, V.3    Krishnamra, N.4
  • 69
    • 0016745040 scopus 로고
    • Further studies on the action of prolactin on fluid and ion absorption by the rat jejunum
    • Mainoya J. (1975) Further studies on the action of prolactin on fluid and ion absorption by the rat jejunum. Endocrinology 96: 1158–1164.
    • (1975) Endocrinology , vol.96 , pp. 1158-1164
    • Mainoya, J.1
  • 70
    • 0035118780 scopus 로고    scopus 로고
    • Biphasic action of prolactin in the regulation of murine Leydig tumor cell functions
    • Manna P. El-Hefnawy T. Kero J. Huhtaniemi I. (2001) Biphasic action of prolactin in the regulation of murine Leydig tumor cell functions. Endocrinology 142: 308–318.
    • (2001) Endocrinology , vol.142 , pp. 308-318
    • Manna, P.1    El-Hefnawy, T.2    Kero, J.3    Huhtaniemi, I.4
  • 72
    • 0030160013 scopus 로고    scopus 로고
    • Skeletal development and bone turnover revisited
    • Matkovic V. (1996) Skeletal development and bone turnover revisited. J Clin Endocrinol Metab 81: 2013–2016.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 2013-2016
    • Matkovic, V.1
  • 74
    • 34249291613 scopus 로고    scopus 로고
    • Bone mineral density changes over a year in young females with schizophrenia: relationship to medication and endocrine variables
    • Meaney A. O’Keane V. (2007) Bone mineral density changes over a year in young females with schizophrenia: relationship to medication and endocrine variables. Schizophr Res 93: 136–143.
    • (2007) Schizophr Res , vol.93 , pp. 136-143
    • Meaney, A.1    O’Keane, V.2
  • 75
    • 2642560342 scopus 로고    scopus 로고
    • Effects of long-term prolactin-raising antipsychotic medication on bone mineral density in patients with schizophrenia
    • Meaney A. Smith S. Howes O. O’Brien M. Murray R. O’Keane V. (2004) Effects of long-term prolactin-raising antipsychotic medication on bone mineral density in patients with schizophrenia. Br J Psychiatry 184: 503–508.
    • (2004) Br J Psychiatry , vol.184 , pp. 503-508
    • Meaney, A.1    Smith, S.2    Howes, O.3    O’Brien, M.4    Murray, R.5    O’Keane, V.6
  • 76
    • 77953407628 scopus 로고    scopus 로고
    • Relation of serum serotonin levels to bone density and structural parameters in women
    • Modder U. Achenbach S. Amin S. Riggs B. Melton L. 3rd Khosla S. (2010) Relation of serum serotonin levels to bone density and structural parameters in women. J Bone Miner Res 25: 415–422.
    • (2010) J Bone Miner Res , vol.25 , pp. 415-422
    • Modder, U.1    Achenbach, S.2    Amin, S.3    Riggs, B.4    Melton, L.5    Khosla, S.6
  • 77
    • 84855905214 scopus 로고    scopus 로고
    • Trabecular bone loss after administration of the second-generation antipsychotic risperidone is independent of weight gain
    • Motyl K. Dick-de-Paula I. Maloney A. Lotinun S. Bornstein S. de Paula F. et al. (2012) Trabecular bone loss after administration of the second-generation antipsychotic risperidone is independent of weight gain. Bone 50: 490–498.
    • (2012) Bone , vol.50 , pp. 490-498
    • Motyl, K.1    Dick-de-Paula, I.2    Maloney, A.3    Lotinun, S.4    Bornstein, S.5    de Paula, F.6
  • 78
    • 0035857351 scopus 로고    scopus 로고
    • Osteoporosis prevention, diagnosis, and therapy
    • NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy (2001) Osteoporosis prevention, diagnosis, and therapy. JAMA 285: 785–795.
    • (2001) JAMA , vol.285 , pp. 785-795
  • 79
    • 0036154355 scopus 로고    scopus 로고
    • Altered bone turnover in chlorpromazine-challenged rats and its effect on 1alpha-hydroxyvitamin D3 administration in vivo
    • Oh-ie K. Miyazaki T. Koyama I. Hokari S. Komoda T. (2002) Altered bone turnover in chlorpromazine-challenged rats and its effect on 1alpha-hydroxyvitamin D3 administration in vivo. J Bone Miner Metab 20: 21–27.
    • (2002) J Bone Miner Metab , vol.20 , pp. 21-27
    • Oh-ie, K.1    Miyazaki, T.2    Koyama, I.3    Hokari, S.4    Komoda, T.5
  • 80
    • 84870603148 scopus 로고    scopus 로고
    • National trends in the office-based treatment of children, adolescents, and adults with antipsychotics
    • Olfson M. Blanco C. Liu S. Wang S. Correll C. (2012) National trends in the office-based treatment of children, adolescents, and adults with antipsychotics. Arch Gen Psychiatry 69: 1247-1256.
    • (2012) Arch Gen Psychiatry , vol.69 , pp. 1247-1256
    • Olfson, M.1    Blanco, C.2    Liu, S.3    Wang, S.4    Correll, C.5
  • 82
    • 77957118458 scopus 로고    scopus 로고
    • Double-blind randomized trial of risperidone versus divalproex in pediatric bipolar disorder
    • Pavuluri M. Henry D. Findling R. Parnes S. Carbray J. Mohammed T. et al. (2010) Double-blind randomized trial of risperidone versus divalproex in pediatric bipolar disorder. Bipolar Dis 12: 593–605.
    • (2010) Bipolar Dis , vol.12 , pp. 593-605
    • Pavuluri, M.1    Henry, D.2    Findling, R.3    Parnes, S.4    Carbray, J.5    Mohammed, T.6
  • 83
    • 0345283216 scopus 로고    scopus 로고
    • The regulatory effect of hormones and growth factors on the pubertal growth spurt
    • Phillip M. Lazar L. (2003) The regulatory effect of hormones and growth factors on the pubertal growth spurt. Endocrinologist 13: 465–469.
    • (2003) Endocrinologist , vol.13 , pp. 465-469
    • Phillip, M.1    Lazar, L.2
  • 84
    • 23244436740 scopus 로고    scopus 로고
    • Bone density measurements in children and adolescents. quantitative computed tomography versus dual-energy x-ray absorptiometry
    • Pitukcheewanont P. Chen P. (2005) Bone density measurements in children and adolescents. quantitative computed tomography versus dual-energy x-ray absorptiometry. Endocrinologist 15: 232–239.
    • (2005) Endocrinologist , vol.15 , pp. 232-239
    • Pitukcheewanont, P.1    Chen, P.2
  • 85
    • 79960369701 scopus 로고    scopus 로고
    • Metabolic and neurological complications of second-generation antipsychotic use in children: a systematic review and meta-analysis of randomized controlled trials
    • Pringsheim T. Lam D. Ching H. Patten S. (2011) Metabolic and neurological complications of second-generation antipsychotic use in children: a systematic review and meta-analysis of randomized controlled trials. Drug Safety 34: 651–668.
    • (2011) Drug Safety , vol.34 , pp. 651-668
    • Pringsheim, T.1    Lam, D.2    Ching, H.3    Patten, S.4
  • 86
    • 0035085320 scopus 로고    scopus 로고
    • Changes in bone density during childhood and adolescence: an approach based on bone's biological organization
    • Rauch F. Schoenau E. (2001) Changes in bone density during childhood and adolescence: an approach based on bone's biological organization. J Bone Miner Res 16: 597–604.
    • (2001) J Bone Miner Res , vol.16 , pp. 597-604
    • Rauch, F.1    Schoenau, E.2
  • 87
    • 21344434103 scopus 로고    scopus 로고
    • Risperidone treatment of autistic disorder: longer-term benefits and blinded discontinuation after 6 months
    • Research Units on Pediatric Psychopharmacology Autism Network (2005) Risperidone treatment of autistic disorder: longer-term benefits and blinded discontinuation after 6 months. Am J Psychiatry 162: 1361–1369.
    • (2005) Am J Psychiatry , vol.162 , pp. 1361-1369
  • 88
    • 33645905430 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled study of risperidone maintenance treatment in children and adolescents with disruptive behavior disorders
    • Reyes M. Buitelaar J. Toren P. Augustyns I. Eerdekens M. (2006a) A randomized, double-blind, placebo-controlled study of risperidone maintenance treatment in children and adolescents with disruptive behavior disorders. Am J Psychiatry 163: 402–410.
    • (2006) Am J Psychiatry , vol.163 , pp. 402-410
    • Reyes, M.1    Buitelaar, J.2    Toren, P.3    Augustyns, I.4    Eerdekens, M.5
  • 89
    • 33745133029 scopus 로고    scopus 로고
    • Long-term use of risperidone in children with disruptive behavior disorders and subaverage intelligence: efficacy, safety, and tolerability
    • Reyes M. Croonenberghs J. Augustyns I. Eerdekens M. (2006b) Long-term use of risperidone in children with disruptive behavior disorders and subaverage intelligence: efficacy, safety, and tolerability. J Child Adolesc Psychopharmacol 16: 260–272.
    • (2006) J Child Adolesc Psychopharmacol , vol.16 , pp. 260-272
    • Reyes, M.1    Croonenberghs, J.2    Augustyns, I.3    Eerdekens, M.4
  • 90
    • 33644804238 scopus 로고    scopus 로고
    • Long-term safety and efficacy of risperidone in children with disruptive behaviour disorders. results of a 2-year extension study
    • Reyes M. Olah R. Csaba K. Augustyns I. Eerdekens M. (2006c) Long-term safety and efficacy of risperidone in children with disruptive behaviour disorders. results of a 2-year extension study. Eur Child Adolesc Psychiatry 15: 97–104.
    • (2006) Eur Child Adolesc Psychiatry , vol.15 , pp. 97-104
    • Reyes, M.1    Olah, R.2    Csaba, K.3    Augustyns, I.4    Eerdekens, M.5
  • 91
    • 0034711425 scopus 로고    scopus 로고
    • Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds
    • Richelson E. Souder T. (2000) Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds. Life Sci 68: 29–39.
    • (2000) Life Sci , vol.68 , pp. 29-39
    • Richelson, E.1    Souder, T.2
  • 92
    • 69549086733 scopus 로고    scopus 로고
    • Antipsychotic medication in children and adolescents: a descriptive review of the effects on prolactin level and associated side effects
    • Roke Y. van Harten P. Boot A. Buitelaar J. (2009) Antipsychotic medication in children and adolescents: a descriptive review of the effects on prolactin level and associated side effects. J Child Adolesc Psychopharmacol 19: 403–414.
    • (2009) J Child Adolesc Psychopharmacol , vol.19 , pp. 403-414
    • Roke, Y.1    van Harten, P.2    Boot, A.3    Buitelaar, J.4
  • 93
    • 4644271084 scopus 로고    scopus 로고
    • Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia
    • Roth B. Sheffler D. Kroeze W. (2004) Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia. Nat Rev Drug Discov 3: 353–359.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 353-359
    • Roth, B.1    Sheffler, D.2    Kroeze, W.3
  • 94
    • 78650658495 scopus 로고    scopus 로고
    • Some effects of risperidone and quetiapine on growth parameters and hormone levels in young pigtail macaques
    • Sackett G. Unis A. Crouthamel B. (2010) Some effects of risperidone and quetiapine on growth parameters and hormone levels in young pigtail macaques. J Child Adolesc Psychopharmacol 20: 489–493.
    • (2010) J Child Adolesc Psychopharmacol , vol.20 , pp. 489-493
    • Sackett, G.1    Unis, A.2    Crouthamel, B.3
  • 95
    • 80052099080 scopus 로고    scopus 로고
    • Age-grouped differences in adverse drug events from psychotropic medication
    • Safer D. (2011) Age-grouped differences in adverse drug events from psychotropic medication. J Child Adolesc Psychopharmacol 21: 299–309.
    • (2011) J Child Adolesc Psychopharmacol , vol.21 , pp. 299-309
    • Safer, D.1
  • 96
    • 84878076871 scopus 로고    scopus 로고
    • Prolactin serum concentrations during aripiprazole treatment in youth
    • in press
    • Safer D. Calarge C. Safer A. (2013) Prolactin serum concentrations during aripiprazole treatment in youth. J Child Adolesc Psychopharmacol, in press.
    • (2013) J Child Adolesc Psychopharmacol
    • Safer, D.1    Calarge, C.2    Safer, A.3
  • 97
    • 0020503695 scopus 로고
    • Bone density in amenorrheic women with and without hyperprolactinemia
    • Schlechte J. Sherman B. Martin R. (1983) Bone density in amenorrheic women with and without hyperprolactinemia. J Clin Endocrinol Metab 56: 1120–1123.
    • (1983) J Clin Endocrinol Metab , vol.56 , pp. 1120-1123
    • Schlechte, J.1    Sherman, B.2    Martin, R.3
  • 98
    • 0026783954 scopus 로고
    • A longitudinal analysis of premenopausal bone loss in healthy women and women with hyperprolactinemia
    • Schlechte J. Walkner L. Kathol M. (1992) A longitudinal analysis of premenopausal bone loss in healthy women and women with hyperprolactinemia. J Clin Endocrinol Metab 75: 698–703.
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 698-703
    • Schlechte, J.1    Walkner, L.2    Kathol, M.3
  • 99
    • 28044444896 scopus 로고    scopus 로고
    • From mechanostat theory to development of the ‘functional muscle-bone-unit’
    • Schoenau E. (2005) From mechanostat theory to development of the ‘functional muscle-bone-unit’. J Musculoskelet Neuronal Interact 5: 232–238.
    • (2005) J Musculoskelet Neuronal Interact , vol.5 , pp. 232-238
    • Schoenau, E.1
  • 100
    • 49749096387 scopus 로고    scopus 로고
    • Prolactin decreases the expression ratio of receptor activator of nuclear factor kappaB ligand/osteoprotegerin in human fetal osteoblast cells
    • Seriwatanachai D. Charoenphandhu N. Suthiphongchai T. Krishnamra N. (2008a) Prolactin decreases the expression ratio of receptor activator of nuclear factor kappaB ligand/osteoprotegerin in human fetal osteoblast cells. Cell Biol Int 32: 1126-1135.
    • (2008) Cell Biol Int , vol.32 , pp. 1126-1135
    • Seriwatanachai, D.1    Charoenphandhu, N.2    Suthiphongchai, T.3    Krishnamra, N.4
  • 101
    • 67650064643 scopus 로고    scopus 로고
    • Evidence for direct effects of prolactin on human osteoblasts: inhibition of cell growth and mineralization
    • Seriwatanachai D. Krishnamra N. van Leeuwen J. (2009) Evidence for direct effects of prolactin on human osteoblasts: inhibition of cell growth and mineralization. J Cell Biochem 107: 677–685.
    • (2009) J Cell Biochem , vol.107 , pp. 677-685
    • Seriwatanachai, D.1    Krishnamra, N.2    van Leeuwen, J.3
  • 102
    • 39149089665 scopus 로고    scopus 로고
    • Prolactin directly enhances bone turnover by raising osteoblast-expressed receptor activator of nuclear factor kappaB ligand/osteoprotegerin ratio
    • Seriwatanachai D. Thongchote K. Charoenphandhu N. Pandaranandaka J. Tudpor K. Teerapornpuntakit J. et al. (2008b) Prolactin directly enhances bone turnover by raising osteoblast-expressed receptor activator of nuclear factor kappaB ligand/osteoprotegerin ratio. Bone 42: 535–546.
    • (2008) Bone , vol.42 , pp. 535-546
    • Seriwatanachai, D.1    Thongchote, K.2    Charoenphandhu, N.3    Pandaranandaka, J.4    Tudpor, K.5    Teerapornpuntakit, J.6
  • 103
    • 63749097354 scopus 로고    scopus 로고
    • The effects of hyperprolactinemia on bone and fat
    • Shibli-Rahhal A. Schlechte J. (2009) The effects of hyperprolactinemia on bone and fat. Pituitary 12: 96–104.
    • (2009) Pituitary , vol.12 , pp. 96-104
    • Shibli-Rahhal, A.1    Schlechte, J.2
  • 104
    • 55749083565 scopus 로고    scopus 로고
    • Double-blind comparison of first- and second-generation antipsychotics in early-onset schizophrenia and schizo-affective disorder: findings from the Treatment of Early-Onset Schizophrenia Spectrum Disorders (TEOSS) study
    • Sikich L. Frazier J. McClellan J. Findling R. Vitiello B. Ritz L. et al. (2008) Double-blind comparison of first- and second-generation antipsychotics in early-onset schizophrenia and schizo-affective disorder: findings from the Treatment of Early-Onset Schizophrenia Spectrum Disorders (TEOSS) study. Am J Psychiatry 165: 1420–1431.
    • (2008) Am J Psychiatry , vol.165 , pp. 1420-1431
    • Sikich, L.1    Frazier, J.2    McClellan, J.3    Findling, R.4    Vitiello, B.5    Ritz, L.6
  • 105
    • 20544469661 scopus 로고    scopus 로고
    • Quantitative bone analysis in children: current methods and recommendations
    • Specker B. Schoenau E. (2005) Quantitative bone analysis in children: current methods and recommendations. J Pediatr 146: 726–731.
    • (2005) J Pediatr , vol.146 , pp. 726-731
    • Specker, B.1    Schoenau, E.2
  • 106
    • 0028917001 scopus 로고
    • Plasma levels of parathyroid hormone-related peptide are elevated in hyperprolactinemia and correlated to bone density status
    • Stiegler C. Leb G. Kleinert R. Warnkross H. Ramschak-Schwarzer S. Lipp R. et al. (1995) Plasma levels of parathyroid hormone-related peptide are elevated in hyperprolactinemia and correlated to bone density status. J Bone Miner Res 10: 751–759.
    • (1995) J Bone Miner Res , vol.10 , pp. 751-759
    • Stiegler, C.1    Leb, G.2    Kleinert, R.3    Warnkross, H.4    Ramschak-Schwarzer, S.5    Lipp, R.6
  • 107
    • 1542355444 scopus 로고    scopus 로고
    • The testes, disorders of sexual differentiation and puberty in the male
    • In: Sperling M. (ed.), 2nd ed., Philadelphia, PA: Sauders
    • Styne D. (2002) The testes, disorders of sexual differentiation and puberty in the male. In: Sperling M. (ed.), Pediatric endocrinology, 2nd ed. Philadelphia, PA: Sauders.
    • (2002) Pediatric endocrinology
    • Styne, D.1
  • 108
    • 4644297021 scopus 로고    scopus 로고
    • Prolactin directly stimulated the solvent drag-induced calcium transport in the duodenum of female rats
    • Tanrattana C. Charoenphandhu N. Limlomwongse L. Krishnamra N. (2004) Prolactin directly stimulated the solvent drag-induced calcium transport in the duodenum of female rats. Biochim Biophys Act 1665: 81–91.
    • (2004) Biochim Biophys Act , vol.1665 , pp. 81-91
    • Tanrattana, C.1    Charoenphandhu, N.2    Limlomwongse, L.3    Krishnamra, N.4
  • 109
    • 0026778671 scopus 로고
    • Longitudinal monitoring of bone mass accumulation in healthy adolescents: evidence for a marked reduction after 16 years of age at the levels of lumbar spine and femoral neck in female subjects
    • Theintz G. Buchs B. Rizzoli R. Slosman D. Clavien H. Sizonenko P. et al. (1992) Longitudinal monitoring of bone mass accumulation in healthy adolescents: evidence for a marked reduction after 16 years of age at the levels of lumbar spine and femoral neck in female subjects. J Clin Endocrinol Metab 75: 1060–1065.
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 1060-1065
    • Theintz, G.1    Buchs, B.2    Rizzoli, R.3    Slosman, D.4    Clavien, H.5    Sizonenko, P.6
  • 110
    • 0037098915 scopus 로고    scopus 로고
    • Adrenergic regulation of bone metabolism: possible involvement of sympathetic innervation of osteoblastic and osteoclastic cells
    • Togari A. (2002) Adrenergic regulation of bone metabolism: possible involvement of sympathetic innervation of osteoblastic and osteoclastic cells. Microscopy Res Technique 58: 77–84.
    • (2002) Microscopy Res Technique , vol.58 , pp. 77-84
    • Togari, A.1
  • 112
    • 28944443143 scopus 로고    scopus 로고
    • Long-term prolactin exposure differentially stimulated the transcellular and solvent drag-induced calcium transport in the duodenum of ovariectomized rats
    • Tudpor K. Charoenphandhu N. Saengamnart W. Krishnamra N. (2005) Long-term prolactin exposure differentially stimulated the transcellular and solvent drag-induced calcium transport in the duodenum of ovariectomized rats. Exp Biol Med 230: 836–844.
    • (2005) Exp Biol Med , vol.230 , pp. 836-844
    • Tudpor, K.1    Charoenphandhu, N.2    Saengamnart, W.3    Krishnamra, N.4
  • 114
    • 77950532014 scopus 로고    scopus 로고
    • Psychotropic drugs have contrasting skeletal effects that are independent of their effects on physical activity levels
    • Warden S. Hassett S. Bond J. Rydberg J. Grogg J. Hilles E. et al. (2010) Psychotropic drugs have contrasting skeletal effects that are independent of their effects on physical activity levels. Bone 46: 985–992.
    • (2010) Bone , vol.46 , pp. 985-992
    • Warden, S.1    Hassett, S.2    Bond, J.3    Rydberg, J.4    Grogg, J.5    Hilles, E.6
  • 115
    • 72049084257 scopus 로고    scopus 로고
    • The emerging role of serotonin (5-hydroxytryptamine) in the skeleton and its mediation of the skeletal effects of low-density lipoprotein receptor-related protein 5 (LRP5)
    • Warden S. Robling A. Haney E. Turner C. Bliziotes M. (2010) The emerging role of serotonin (5-hydroxytryptamine) in the skeleton and its mediation of the skeletal effects of low-density lipoprotein receptor-related protein 5 (LRP5). Bone 46: 4–12.
    • (2010) Bone , vol.46 , pp. 4-12
    • Warden, S.1    Robling, A.2    Haney, E.3    Turner, C.4    Bliziotes, M.5
  • 117
    • 56349162283 scopus 로고    scopus 로고
    • LRP5 controls bone formation by inhibiting serotonin synthesis in the duodenum
    • Yadav V. Ryu J. Suda N. Tanaka K. Gingrich J. Schutz G. et al. (2008) LRP5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell 135: 825–837.
    • (2008) Cell , vol.135 , pp. 825-837
    • Yadav, V.1    Ryu, J.2    Suda, N.3    Tanaka, K.4    Gingrich, J.5    Schutz, G.6
  • 118
    • 33745203732 scopus 로고    scopus 로고
    • Pediatric reference intervals for bone markers
    • Yang L. Grey V. (2006) Pediatric reference intervals for bone markers. Clin Biochem 39: 561–568.
    • (2006) Clin Biochem , vol.39 , pp. 561-568
    • Yang, L.1    Grey, V.2
  • 119
    • 58249106842 scopus 로고    scopus 로고
    • Lithium's effect on bone mineral density
    • Zamani A. Omrani G. Nasab M. (2009) Lithium's effect on bone mineral density. Bone 44: 331–334.
    • (2009) Bone , vol.44 , pp. 331-334
    • Zamani, A.1    Omrani, G.2    Nasab, M.3
  • 120
    • 33644580673 scopus 로고    scopus 로고
    • Reference data for the whole body, lumbar spine, and proximal femur for American children relative to age, gender, and body size
    • Zemel B. Leonard M. Kalkward H. Specker B. Moyer-Mileur L. Shepherd J. et al. (2004) Reference data for the whole body, lumbar spine, and proximal femur for American children relative to age, gender, and body size. J Bone Miner Res 19: S231.
    • (2004) J Bone Miner Res , vol.19 , pp. S231
    • Zemel, B.1    Leonard, M.2    Kalkward, H.3    Specker, B.4    Moyer-Mileur, L.5    Shepherd, J.6
  • 121
    • 79959887445 scopus 로고    scopus 로고
    • Second generation antipsychotics (SGAs) for non-psychotic disorders in children and adolescents: a review of the randomized controlled studies
    • Zuddas A. Zanni R. Usala T. (2011) Second generation antipsychotics (SGAs) for non-psychotic disorders in children and adolescents: a review of the randomized controlled studies. Eur Neuropsychopharmacol 21: 600–620.
    • (2011) Eur Neuropsychopharmacol , vol.21 , pp. 600-620
    • Zuddas, A.1    Zanni, R.2    Usala, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.