Osteoblasts are a new target for prolactin: Analysis of bone formation in prolactin receptor knockout mice

Endocrinology

Volumn 140, Issue 1, 1999, Pages 96-105

  Clément Lacroix, Philippe ^a   Ormandy, Christopher ^b   Lepescheux, Liên ^c   Ammann, Patrick ^d   Damotte, Diane ^e   Goffin, Vincent ^a   Bouchard, Brigitte ^a   Amling, Michael ^f   Gaillard Kelly, Martine ^c   Binart, Nadine ^a   Baron, Roland ^c,f   Kelly, Paul A ^a  

^a INSERM   (France)

^b GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c SANOFI   (France)

^d WORLD HEALTH ORGANIZATION   (Switzerland)

^e HÔPITAL NECKER ENFANTS MALADES   (France)

^f YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; PARATHYROID HORMONE DERIVATIVE; PROGESTERONE; PROLACTIN; PROLACTIN RECEPTOR; TESTOSTERONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MASS; CALVARIA; CELL CULTURE; DUAL ENERGY X RAY ABSORPTIOMETRY; EXON; MORPHOMETRICS; MOUSE; NONHUMAN; OLIGONUCLEOTIDE PROBE; OSSIFICATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROLACTIN BLOOD LEVEL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 0013577437     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.140.1.6436     Document Type: Article

References (48)

1. 1. Cohn MJ, Tickle C 1996 Limbs: a model for pattern formation within the vertebrate body plan. Trends Genet 12:253-257
2. 2. Hogan BL 1996 Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev 10:1580-1594
3. 3. Cross NA, Hillman LAS, Krause GF 1995 Changes in bone mineral density and markers of bone remodeling during lactation and postweaning in women consuming high amounts of calcium. J Bone Miner Res 10:1312-1320
4. 4. Schlechte JA 1995 Clinical impact of hyperprolactinaemia. Bailliere Clin Endocrinol Metab 9:359-366
5. 5. Sowers MF, Hollis BW, Shapiro B, Randolph J, Janney CA, Zhang D, Schork A, Crutchfield M, Stanczyk F, Russel-Aulet M 1996 Elevated parathyroid hormone-related peptide associated with lactation and bone density loss. JAMA 276:549-554
6. 6. Lopez JM, Gonzalez G, Reyes V, Campino C, Diaz S 1997 Bone turnover and density in healthy women during breastfeeding and after weaning. Osteoporos Int 6:153-159
7. 7. Royster M, Driscoll P, Kelly PA, Freemark M 1995 The prolactin receptor in the fetal rat: cellular localization of messenger RNA, immunoreactive protein, and ligand binding activity and induction of expression in late gestation. Endocrinology 136:3892-3900
8. 8. Freemark M, Driscoll P, Maaskant R, Petryk A, Kelly PA 1997 Ontogenesis of prolactin receptors in the human fetus in early gestation. Implications for tissue differentiation and development. J Clin Invest 99:1107-1117
9. 9. Tzeng SJ, Linzer DI 1997 Prolactin receptor expression in the developing mouse embryo. Mol Reprod Dev 48:45-52
10. 10. Bataille-Simoneau N, Gerland K, Chappard D, Basle MF, Mercier L 1996 Expression of prolactin receptors in human osteosarcoma cells. Biochem Biophys Res Commun 229:323-328
11. 11. Ben-Jonathan N, Mershon JL, Allen DL, Steinmetz RW 1996 Extrapituitary prolactin: distribution, regulation, functions, and clinical aspects. Endocr Rev 17:639-669
12. 12. Bole-Feysot C, Coffin V, Edery M, Binart N, Kelly PA 1998 Prolactin and its receptor: actions, signal transduction pathways and phenotypes observed in prolactin receptor knockout mice. Endocr Rev 19:225-268
13. 13. Goffin V, Kelly PA 1996 Prolactin and growth hormone receptors. Clin Endocrinol (Oxf) 45:247-255
14. 14. Goffin V, Shiverick KT, Kelly PA, Martial JA 1996 Sequence-function relationships within the expanding family of prolactin, growth hormone, placental lactogen and related proteins in mammals. Endocr Rev 17:385-410
15. 15. Clarke DL, Linzer DH 1993 Changes in prolactin receptor expression during pregnancy in the mouse ovary. Endocrinology 133:224-232
16. 16. Ormandy CJ, Camus A, Barra J, Damotte D, Lucas BK, Buteau H, Edery M, Brousse N, Babinet C, Binart N, Kelly PA 1997 Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse. Genes Dev 11:167-178
17. 17. Ormandy CJ, Binart N, Helloco C, Kelly PA 1998 The mouse prolactin receptor gene: genomic organization reveals alternative promoter usage and generation of isoforms via alternative 3'-exon splicing. DNA Cell Biol 17:761-770
18. 18. Davis JA, Linzer DH 1989 Expression of multiple forms of the prolactin receptor. Mol Endocrinol 3:674-680
19. 19. Das R, Vonderhaar BK 1995 Transduction of prolactin's (PRL) growth signal through both long and short forms of the PRL receptor. Mol Endocrinol 9:1750-1759
20. 20. Gouilleux F, Pallard C, Dusanter-Fourt I, Wakao H, Haldosen LA, Norstedt G, Levy D, Groner B 1995 Prolactin, growth hormone, erythropoietin and granulocyte-macrophage colony stimulating factor induce MGF-Stat5 DNA binding activity. EMBO J 14:2005-2013
21. 21. Lebrun JJ, Ali S, Ullrich A, Kelly PA 1995 Proline-rich sequence-mediated JAK2 association to the prolactin receptor is required but not sufficient for signal transduction. J Biol Chem 270:10664-10670
22. 22. Talamantes F, Ogren L 1988 The placenta as an endocrine organ: polypeptides A2-Knobil, E A2-Neill, J. Physiol Reprod 2093-2133
23. 23. Lucas BK, Ormandy C, Binart N, Bridges RS, Kelly PA 1998 Null mutation of prolactin receptor gene produces a defect in maternal behavior. Endocrinology 139:4102-4107
24. 23a. Heath JK, Atkinson SJ, Meikle MC, Reynolds JJ 1984 Mouse osteoblasts synthesize collagenase in response to bone resorbing agents. Biochim Biophys Acta 802:151-154
25. 24. Takahashi N, Yamana H, Yoshiki S, Roodman GD, Mundy GR, Jones SJ, Boyde A, Suda T 1988 Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures. Endocrinology 122:1373-1382
26. 25. Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
27. 26. Okamura H, Zachwieja J, Raguet S, Kelly PA 1989 Characterization and application of monoclonal antibodies to the prolactin receptor. Endocrinology 124:2499-2508
28. 27. Vignery A, Baron R 1980 Dynamic histomorphometry of alveolar bone remodeling in the adult rat. Anat Rec 196:191-200
29. 28 Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR 1987 Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 2:595-610
30. 29. Ammann P, Rizzoli R, Bonjour JP, Bourin S, Meyer JM, Vassili P, Garcia I 1997 Transgenic mice expressing soluble tumor necrosis factor-receptor are protected against bone loss caused by estrogen deficiency. J Clin Invest 99:1699-1703
31. 30. Kolozar S, Gellen J, Kovacs L 1997 The value of plasma prolactin level determination in the diagnosis of postmenopausal osteoporosis. Orv Hetil 138:71-73
32. 31. Krishnamra N, Lotinun S, Limlomwongse L 1993 Acute effect and mechanism of action of prolactin on the in situ passive calcium absorption in rat. Bone Miner 23:253-266
33. 32. Krishnamra N, Seemoung J 1996 Effects of acute and long-term administration of prolactin on bone 45Ca uptake, calcium deposit, and calcium resorption in weaned, young, and mature rats. Can J Physiol Pharmacol 74:1157-1165
34. 33. Krishnamra N, Seemoung J, Limlomwongse L 1997 Acute effect of prolactin on bone 45Ca accumulation in rats. Endocr J 44:257-264
35. 34. Miller SC, Bowman BM, Jee WS 1995 Available animal models of osteopenia-small and large. Bone 17:117S-123S
36. 35. Fujimaki T, Kurabayashi T, Ootani T, Yamamoto Y, Yasuda M, Tanaka K 1994 A study on bone metabolism in woman with hyperprolactinemia. Nipp Sanka Fuj Gak Zas 46:423-428
37. 36 Horseman ND, Zhao W, Montecino-Rodriguez E, Tanaka M, Nakashima K, Engle SJ, Smith F, Markoff E, Dorshkind K 1997 Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene. EMBO J 16:6926-6935
38. 3. Biosci Rep 13:27-39
39. 38. Lippuner K, Zehnder HJ, Casez JP, Takkinen R, Jeager P 1997 PTH-related protein is released into the mother's bloodstream during lactation: evidence for beneficial effects on maternal calcium-phosphate metabolism. J Bone Miner Res 11:1394-1399
40. 39. Rider V, Psychoyos A 1994 Inhibition of progesterone receptor function results in loss of basic fibroblast growth factor expression and stromal cell proliferation during uterine remodeling in the pregnant rat. J Endocrinol 140:239-249
41. 40. Korach KS 1994 Insights from the study of animals lacking functional estrogen receptor. Science 266:1524-1527
42. 41. Zhou Y, Xu BC, Maheshwari HG, He L, Reed M, Lozykowski M, Okada S, Cataldo L, Coschigano K, Wagner TE, Baumann G, Kopchick JJ 1997 A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse). Proc Natl Acad Sci USA 94:13215-13220
43. 42. Ding JH, Sheckter CB, Drinkwater BL, Soules MR, Bremner WJ 1988 High serum cortisol levels in exercise-associated amenorrhea. Ann Intern Med 108:530-534
44. 43. Kapur S, Tamada H, Dey SK, Andrews GK 1992 Expression of insulin-like growth factor-I (IGF-I) and its receptor in the peri-implantation mouse uterus, and cell-specific regulation of IGF-I gene expression by estradiol and progesterone. Biol Reprod 46:208-219
45. 44. Beck F, Tucci J, Senior PV 1993 Expression of parathyroid hormone-related protein mRNA by uterine tissue and extraembryonic membranes during gestation in rats. J Reprod Fertil 99:343-352
46. 45. Sutherland AE, Calarco PG, Damski CH 1993 Developmental regulation of integrin expression at the time of implantation in the mouse embryo. Development 119:1175-1186
47. 46. Migliaccio S, Newbold RR, McLachlan JA, Korach KS 1995 Alterations in estrogen levels during development affects the skeleton: use of an animal model. Environ Health Perspect [Suppl 7] 103:95-7:95-97
48. 47 Wysolmerski JJ, McCaughern-Carucci JF, Daifotis AG, Broadus AE, Philbrick WM 1995 Overexpression of parathyroid hormone-related protein or parathyroid hormone in transgenic mice impairs branching morphogenesis during mammary gland development. Development 121:3539-3547