Oral morphine dosing predictions based on single dose in healthy children undergoing surgery

Paediatric Anaesthesia

Volumn 27, Issue 1, 2017, Pages 28-36

  Dawes, Joy M ^a   Cooke, Erin M ^b   Hannam, Jacqueline A ^c   Brand, Katherine A ^d   Winton, Pamela ^e   Jimenez Mendez, Ricardo ^b   Aleksa, Katarina ^f   Lauder, Gillian R ^b   Carleton, Bruce C ^b   Koren, Gideon ^f   Rieder, Michael J ^g   Anderson, Brian J ^c   Montgomery, Carolyne J ^b  

^a GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

^d ST THOMAS HOSPITAL   (United Kingdom)

^e ROYAL HOSPITAL FOR SICK CHILDREN   (United Kingdom)

^f HOSPITAL FOR SICK CHILDREN   (Canada)

^g UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

analgesics; morphine; opioids; pediatrics; pharmacokinetics; toxicity

Indexed keywords

MORPHINE; NARCOTIC ANALGESIC AGENT;

ANALGESIA; ARTICLE; BLOOD SAMPLING; BREATHING; CHILD; CLINICAL ARTICLE; DOSE TIME EFFECT RELATION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG SAFETY; ELECTIVE SURGERY; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; PEDIATRIC SURGERY; PRESCHOOL CHILD; PRIORITY JOURNAL; SINGLE DRUG DOSE; STEADY STATE; BLOOD; DOSE RESPONSE; FEMALE; MALE; ORAL DRUG ADMINISTRATION; SURGERY;

ADMINISTRATION, ORAL; ANALGESICS, OPIOID; CHILD; CHILD, PRESCHOOL; CHROMATOGRAPHY, LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MALE; MASS SPECTROMETRY; MORPHINE; SURGICAL PROCEDURES, OPERATIVE;

EID: 84997795566     PISSN: 11555645     EISSN: 14609592     Source Type: Journal    
DOI: 10.1111/pan.13020     Document Type: Article

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