The cytoprotective effect of Rumex Aquaticus Herba extract against hydrogen peroxide-induced oxidative stress in AGS cells

Archives of Pharmacal Research

Volumn 39, Issue 12, 2016, Pages 1739-1747

  Cho, Eun Jeong ^a   Um, Seung In ^a   Han, Jeong Hoon ^a   Kim, Byeonghee ^a   Han, Sang Beom ^a   Jeong, Ji Hoon ^a   Kim, Hak Rim ^b   Kim, Inkyeom ^c   Whang, Wan Kyun ^a   Lee, Eunhwa ^a   Sohn, Uy Dong ^a  

^a Chung Ang University   (South Korea)

^b Dankook University   (South Korea)

^c Kyungpook National University School of Medicine   (South Korea)

Author keywords

Anti inflammatory; Antioxidant; Cytoprotection; Herbal extract; Oxidative stress

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ACETOACETIC ACID; CYTOPROTECTIVE AGENT; GLUTATHIONE PEROXIDASE; HEME OXYGENASE 1; HYDROGEN PEROXIDE; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; RUMEX AQUATICUS HERBA EXTRACT; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ARTICLE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; MTT ASSAY; OXIDATIVE STRESS; PROTEIN EXPRESSION; RUMEX AQUATICUS; STOMACH EPITHELIUM; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CELL LINE; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; ISOLATION AND PURIFICATION; METABOLISM; PHYSIOLOGY; RUMEX;

CELL LINE; CELL SURVIVAL; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROGEN PEROXIDE; OXIDATIVE STRESS; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; RUMEX;

EID: 84996920941     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-016-0863-0     Document Type: Article

References (46)

1. Arena V, Pennacchia I, Guerriero G, Mancuso C (2015) The heme oxygenase/biliverdin reductase system in skin cancers. J Biol Regul Homeost Agents 29:259–264
2. Barranco SC, Townsend CM Jr, Casartelli C, Macik BG, Burger NL, Boerwinkle WR, Gourley WK (1983) Establishment and characterization of an in vitro model system for human adenocarcinoma of the stomach. Cancer Res 43:1703–1709
3. Berlett BS, Stadtman ER (1997) Protein oxidation in aging, disease, and oxidative stress. J Biol Chem 272:20313–20316
4. 2: a mediator of esophagitis-induced damage to calcium-release mechanisms in cat lower esophageal sphincter. Am J Physiol Gastrointest Liver Physiol 288:G1170–1178
5. Ceriello A, dello Russo P, Amstad P, Cerutti P (1996) High glucose induces antioxidant enzymes in human endothelial cells in culture. Evidence linking hyperglycemia and oxidative stress. Diabetes 45:471–477
6. Cho JH, Park SY, Lee HS, Whang WK, Sohn UD (2011) The protective effect of Quercetin-3-O-beta-D-glucuronopyranoside on ethanol-induced damage in cultured feline esophageal epithelial cells. Korean J Physiol Pharmacol 15:319–326
7. Das SK, Roy C (2012) The protective role of Aegle marmelos on aspirin-induced gastro-duodenal ulceration in albino rat model: a possible involvement of antioxidants. Saudi J Gastroenterol 18:188–194
8. Foresti R, Hoque M, Monti D, Green CJ, Motterlini R (2005) Differential activation of heme oxygenase-1 by chalcones and rosolic acid in endothelial cells. J Pharmacol Exp Ther 312:686–693
9. Gabryel B, Jarzabek K, Machnik G, Adamczyk J, Belowski D, Obuchowicz E, Urbanek T (2015) Superoxide dismutase 1 and glutathione peroxidase 1 are involved in the protective effect of sulodexide on vascular endothelial cells exposed to oxygen-glucose deprivation. Microvasc Res 103:26–35
10. Guo X, Shin VY, Cho CH (2001) Modulation of heme oxygenase in tissue injury and its implication in protection against gastrointestinal diseases. Life Sci 69:3113–3119
11. Heim KE, Tagliaferro AR, Bobilya DJ (2002) Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships. J Nutr Biochem 13:572–584
12. Jaiswal AK (2004) Nrf2 signaling in coordinated activation of antioxidant gene expression. Free Radic Biol Med 36:1199–1207
13. Jang HS, Han JH, Jeong JY, Sohn UD (2012) Protective effect of ECQ on rat Reflux Esophagitis model. Korean J Physiol Pharmacol 16:455–462
14. Joo M, Kim HS, Kwon TH, Palikhe A, Zaw TS, Jeong JH, Sohn UD (2015) Anti-inflammatory effects of flavonoids on TNBS-induced colitis of rats. Korean J Physiol Pharmacol 19:43–50
15. Jung J, Nam Y, Sohn UD (2012) Inhibitory effects of ECQ on indomethacin-induced gastric damage in rats. Korean J Physiol Pharmacol 16:399–404
16. Kim JS, Song HJ, Ko SK, Whang WK, Sohn UD (2010) Quercetin-3-O-beta-D-glucuronopyranoside (QGC)-induced HO-1 expression through ERK and PI3 K activation in cultured feline esophageal epithelial cells. Fitoterapia 81:85–92
17. Kim YJ, Kim EH, Hahm KB (2012) Oxidative stress in inflammation-based gastrointestinal tract diseases: challenges and opportunities. J Gastroenterol Hepatol 27:1004–1010
18. Kim JM, Kim KM, Park EH, Seo JH, Song JY, Shin SC, Kang HL, Lee WK, Cho MJ, Rhee KH, Youn HS, Baik SC (2013) Anthocyanins from black soybean inhibit Helicobacter pylori-induced inflammation in human gastric epithelial AGS cells. Microbiol Immunol 57:366–373
19. Kim MK, Park HJ, Kim SR, Choi YK, Bae SK, Bae MK (2015) Involvement of heme oxygenase-1 in orexin-A-induced angiogenesis in vascular endothelial cells. Korean J Physiol Pharmacol 19:327–334
20. Kwak HS, Park SY, Nguyen TT, Kim CH, Lee JM, Suh JS, Whang WK, Sohn UD (2012) Protective effect of extract from Rumex aquaticus herba on ethanol-induced gastric damage in rats. Pharmacology 90:288–297
21. Kwiecien S, Brzozowski T, Konturek SJ (2002) Effects of reactive oxygen species action on gastric mucosa in various models of mucosal injury. J Physiol Pharmacol 53:39–50
22. Lee NK, Son KH, Chang HW, Kang SS, Park H, Heo MY, Kim HP (2004) Prenylated flavonoids as tyrosinase inhibitors. Arch Pharm Res 27:1132–1135
23. Lee MJ, Song HJ, Jeong JY, Park SY, Sohn UD (2013) Anti-oxidative and anti-inflammatory effects of QGC in cultured feline esophageal epithelial cells. Korean J Physiol Pharmacol 17:81–87
24. Lim JC, Park SY, Nam Y, Nguyen TT, Sohn UD (2012) The protective effect of eupatilin against hydrogen peroxide-induced injury involving 5-lipoxygenase in Feline esophageal epithelial cells. Korean J Physiol Pharmacol 16:313–320
25. Martin D, Rojo AI, Salinas M, Diaz R, Gallardo G, Alam J, De Galarreta CM, Cuadrado A (2004) Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol. J Biol Chem 279:8919–8929
26. Middleton E Jr, Kandaswami C, Theoharides TC (2000) The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol Rev 52:673–751
27. Min YS, Bai KL, Yim SH, Lee YJ, Song HJ, Kim JH, Ham I, Whang WK, Sohn UD (2006) The effect of luteolin-7-O-beta-D-glucuronopyranoside on gastritis and esophagitis in rats. Arch Pharm Res 29:484–489
28. Min YS, Lee SE, Hong ST, Kim HS, Choi BC, Sim SS, Whang WK, Sohn UD (2009) The inhibitory effect of Quercetin-3-O-beta-D-glucuronopyranoside on gastritis and reflux esophagitis in rats. Korean J Physiol Pharmacol 13:295–300
29. Motterlini R, Foresti R, Bassi R, Green CJ (2000) Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress. Free Radic Biol Med 28:1303–1312
30. Orban-Gyapai O, Raghavan A, Vasas A, Forgo P, Hohmann J, Shah ZA (2014) Flavonoids isolated from Rumex aquaticus exhibit neuroprotective and neurorestorative properties by enhancing neurite outgrowth and synaptophysin. CNS Neurol Disord: Drug Targets 13:1458–1464
31. Pachori AS, Smith A, McDonald P, Zhang L, Dzau VJ, Melo LG (2007) Heme-oxygenase-1-induced protection against hypoxia/reoxygenation is dependent on biliverdin reductase and its interaction with PI3 K/Akt pathway. J Mol Cell Cardiol 43:580–592
32. Paine A, Eiz-Vesper B, Blasczyk R, Immenschuh S (2010) Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential. Biochem Pharmacol 80:1895–1903
33. Pourcel L, Routaboul JM, Cheynier V, Lepiniec L, Debeaujon I (2007) Flavonoid oxidation in plants: from biochemical properties to physiological functions. Trends Plant Sci 12:29–36
34. Pullikotil P, Chen H, Muniyappa R, Greenberg CC, Yang S, Reiter CE, Lee JW, Chung JH, Quon MJ (2012) Epigallocatechin gallate induces expression of heme oxygenase-1 in endothelial cells via p38 MAPK and Nrf-2 that suppresses proinflammatory actions of TNF-alpha. J Nutr Biochem 23:1134–1145
35. Sipponen P, Hyvarinen H (1993) Role of Helicobacter pylori in the pathogenesis of gastritis, peptic ulcer and gastric cancer. Scand J Gastroenterol Suppl 196:3–6
36. Song HJ, Shin CY, Oh TY, Min YS, Park ES, Sohn UD (2009) Eupatilin with heme oxygenase-1-inducing ability protects cultured feline esophageal epithelial cells from cell damage caused by indomethacin. Biol Pharm Bull 32:589–596
37. Spooner R, Yilmaz O (2011) The role of reactive-oxygen-species in microbial persistence and inflammation. Int J Mol Sci 12:334–352
38. Suleyman H, Demirezer LO, Kuruuzum-Uz A (2001) Analgesic and antipyretic activities of Rumex patientia extract on mice and rabbits. Pharmazie 56:815–817
39. Suleyman H, Demirezer LO, Kuruuzum-Uz A (2004) Effects of Rumex patientia root extract on indomethacine and ethanol induced gastric damage in rats. Pharmazie 59:147–149
40. Surh YJ, Kundu JK, Na HK (2008) Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals. Planta Med 74:1526–1539
41. Tobin JM, Sinha B, Ramani P, Saleh AR, Murphy MS (2001) Upper gastrointestinal mucosal disease in pediatric Crohn disease and ulcerative colitis: a blinded, controlled study. J Pediatr Gastroenterol Nutr 32:443–448
42. Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J (2007) Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39:44–84
43. Vasas A, Orban-Gyapai O, Hohmann J (2015) The Genus Rumex: review of traditional uses, phytochemistry and pharmacology. J Ethnopharmacol 175:198–228
44. Yan XM, Joo MJ, Lim JC, Whang WK, Sim SS, Im C, Kim HR, Lee SY, Kim IK, Sohn UD (2011) The effect of quercetin-3-O-beta-D-glucuronopyranoside on indomethacin-induced gastric damage in rats via induction of mucus secretion and down-regulation of ICAM-1 expression. Arch Pharm Res 34:1527–1534
45. Yang Y, Bazhin AV, Werner J, Karakhanova S (2013) Reactive oxygen species in the immune system. Int Rev Immunol 32:249–270
46. Yu BP (1994) Cellular defenses against damage from reactive oxygen species. Physiol Rev 74:139–162