The evolution of drug design at Merck Research Laboratories

Journal of Computer-Aided Molecular Design

Volumn 31, Issue 3, 2017, Pages 255-266

  Brown, Frank K ^a   Sherer, Edward C ^b   Johnson, Scott A ^c   Holloway, M Katharine ^a   Sherborne, Bradley S ^b  

^a MRL   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c Structural Chemistry Department   (United States)

Author keywords

CADD; Modeling; Predictive sciences

Indexed keywords

DIGITAL STORAGE; RESEARCH LABORATORIES;

CADD; DRUG DESIGN; FORTUNE MAGAZINES; INDUSTRIAL REVOLUTIONS; LEAD IDENTIFICATION; MODEL REACTIONS; MODELING; PREDICTIVE MODELS; PREDICTIVE SCIENCE; SMALL MOLECULES;

COMPUTATIONAL CHEMISTRY;

ARTICLE; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG INDUSTRY; MACHINE LEARNING; MOLECULAR DOCKING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN STRUCTURE; RISK ASSESSMENT; BIOLOGY; CHEMISTRY; COMPUTER AIDED DESIGN; DRUG DEVELOPMENT; HUMAN; MEDICINAL CHEMISTRY; MOLECULAR MODEL; PROCEDURES; PROTEIN CONFORMATION; RESEARCH; SOFTWARE; TRENDS;

PROTEIN;

CHEMISTRY, PHARMACEUTICAL; COMPUTATIONAL BIOLOGY; COMPUTER-AIDED DESIGN; DRUG DESIGN; DRUG DISCOVERY; DRUG INDUSTRY; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEINS; RESEARCH; SOFTWARE;

EID: 84996605707     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-016-9993-1     Document Type: Article

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