Toward structure-based predictive tools for the selection of chiral stationary phases for the chromatographic separation of enantiomers

Journal of Chromatography A

Volumn 1467, Issue , 2016, Pages 206-213

  Sheridan, Robert ^a   Schafer, Wes ^a   Piras, Patrick ^b   Zawatzky, Kerstin ^a   Sherer, Edward C ^a   Roussel, Christian ^b   Welch, Christopher J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b AIX MARSEILLE UNIVERSITÉ   (France)

Author keywords

Chiral chromatography; Chiral stationary phases; Chromatographic method development screening; Databases; QSAR

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; COMPUTATIONAL CHEMISTRY; DATABASE SYSTEMS; ENANTIOMERS; INDUSTRIAL RESEARCH; LABORATORIES; LIQUID CHROMATOGRAPHY; MOLECULAR GRAPHICS; MOLECULES; RESEARCH LABORATORIES; SEPARATION; STEREOCHEMISTRY;

CHIRAL CHROMATOGRAPHY; CHIRAL STATIONARY PHASE; CHIRAL STATIONARY PHASIS; CHROMATOGRAPHIC METHODS; CHROMATOGRAPHIC SEPARATIONS; QSAR; QUANTITATIVE STRUCTURE ACTIVITY; STRUCTURAL INFORMATION;

CHROMATOGRAPHY;

ARTICLE; CHIRAL CHROMATOGRAPHY; CHIRAL STATIONARY PHASE; CONTROLLED STUDY; ENANTIOMER; FEEDBACK SYSTEM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEASUREMENT ACCURACY; PARTICLE SIZE; PHYSICAL PHASE; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; TEMPERATURE MEASUREMENT; CHEMICAL ANALYSIS; CHEMICAL MODEL; CHROMATOGRAPHY; FACTUAL DATABASE; PROCEDURES; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; TEMPERATURE;

SOLVENT;

CHEMISTRY TECHNIQUES, ANALYTICAL; CHROMATOGRAPHY; DATABASES, FACTUAL; MODELS, CHEMICAL; SOLVENTS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE;

EID: 84991071400     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2016.05.066     Document Type: Article

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