Senescence-associated DNA methylation is stochastically acquired in subpopulations of mesenchymal stem cells

Aging Cell

Volumn 16, Issue 1, 2017, Pages 183-191

  Franzen, Julia ^a   Zirkel, Anne ^b   Blake, Jonathon ^c   Rath, Björn ^d   Benes, Vladimir ^c   Papantonis, Argyris ^b   Wagner, Wolfgang ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^d RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

bisulfite sequencing; DNA methylation; epigenetics; human umbilical vein endothelial cell; mesenchymal stem cell; senescence

Indexed keywords

DNA; HYDROGEN SULFITE; SULFITE;

AMPLICON; ARTICLE; BISULFITE SEQUENCING; CELL AGING; CELL CLONE; CELL DIFFERENTIATION; CELL SUBPOPULATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CPG ISLAND; DNA METHYLATION; EPIGENETICS; GENE SEQUENCE; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; PREDICTION; PRIORITY JOURNAL; PYROSEQUENCING; UMBILICAL VEIN ENDOTHELIAL CELL; CYTOLOGY; DNA SEQUENCE; GENETIC EPIGENESIS; GENETICS; MARKOV CHAIN; MESENCHYMAL STROMA CELL; METABOLISM; NUCLEOTIDE SEQUENCE;

BASE SEQUENCE; CELL AGING; CELL DIFFERENTIATION; CLONE CELLS; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MESENCHYMAL STROMAL CELLS; SEQUENCE ANALYSIS, DNA; STOCHASTIC PROCESSES; SULFITES;

EID: 84995948345     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12544     Document Type: Article

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