Calcitriol for oral mucositis prevention in patients with fanconi anemia undergoing hematopoietic sct: A double-blind, randomized, placebo-controlled trial

American Journal of Therapeutics

Volumn 23, Issue 6, 2016, Pages e1700-e1708

  Hamidieh, Amir Ali ^a   Sherafatmand, Mona ^b   Mansouri, Ava ^c   Hadjibabaie, Molouk ^b,c   Ashouri, Asieh ^d   Jahangard Rafsanjani, Zahra ^b,c   Gholami, Kheirollah ^b,c   Javadi, Mohammad Reza ^b,c   Ghavamzadeh, Ardeshir ^a   Radfar, Mania ^b,c  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Calcitriol; Fanconi anemia; Hematopoietic stem cell transplantation; Oral mucositis

Indexed keywords

ANTINEOPLASTIC AGENT; CALCITRIOL;

ADOLESCENT; CHILD; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FANCONI ANEMIA; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; INFANT; MALE; PRESCHOOL CHILD; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; STOMATITIS;

ADOLESCENT; ANTINEOPLASTIC AGENTS; CALCITRIOL; CHILD; CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; FANCONI ANEMIA; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; INFANT; MALE; STOMATITIS;

EID: 84995744413     PISSN: 10752765     EISSN: 15363686     Source Type: Journal    
DOI: 10.1097/MJT.0000000000000269     Document Type: Article

References (37)

1. Shimamura A, Alter BP. Pathophysiology and management of inherited bone marrow failure syndromes. Blood Rev. 2010;24:101-122.
2. Tischkowitz MD, Hodgson SV. Fanconi anemia. J Med Genet. 2003;40:1-10.
3. Rosenberg PS, Greene MH, Alter BP. Cancer incidence in persons with Fanconi anemia. Blood. 2003;101:822-826.
4. Rosenberg PS, Alter BP, Ebell W. Cancer risks in Fanconi anemia: findings from the German Fanconi Anemia Registry. Haematologica. 2008;93:511-517.
5. Joenje H, Patel KJ. The emerging genetic and molecular basis of Fanconi anemia. Nat Rev Genet. 2001;2:446-457.
6. Gluckman E, Auerbach AD, Horowitz MM, et al. Bone marrow transplantation for Fanconi anemia. Blood. 1995; 86:2856-2862.
7. Lionel D, Christophe L, Marc A, et al. Oral mucositis induced by anticancer treatments: physiopathology and treatments. Ther Clin Risk Manag. 2006;2:159-168.
8. Birkeland AC, Auerbach AD, Sanborn E, et al. Postoperative clinical radiosensitivity in patients with fanconi anemia and head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg. 2011;137:930-934.
9. Medeiros C, ZanisNeto J, Pasquini R. Bone marrow transplantation for patients with Fanconi anemia: reduced doses of cyclophosphamide without irradiation as conditioning. Bone Marrow Transplant. 1999;24: 849-852.
10. Worthington HV, Clarkson JE, Eden O. Interventions for preventing oral patients with cancer receiving treatment. Cochrane Database Syst Rev. 2010;CD000978.
11. Blijlevens N, Sonis S. Palifermin (recombinant keratinocyte growth factor-1): a pleiotropic growth factor with multiple biological activities in preventing chemotherapy-and radiotherapy-induced mucositis. Ann Oncol. 2007;18:817-826.
12. van Etten E, Mathieu C. Immunoregulation by 1,25-dihydroxy Vitamin D3: basicconcepts. J Steroid Biochem Mol Biol. 2005;97:93-101.
13. Provvedini DM, Tsoukas CD, Deftos LJ, et al. 1,25-dihydroxy1,25(OH)2D3 receptors in human leukocytes. Science. 1983;221:1181-1183.
14. Baeke F, Korf H, Overbergh L, et al. Human T lymphocytes are direct targets of 1,25-dihydroxy Vitamin D3 in the immune system. J Steroid Biochem Mol Biol. 2010;121: 221-227.
15. Zhu Y, Mahon BD, Froicu M, et al. Calcium and 1 alpha, 25-dihydroxyVitamin D3 target the TNF-αlpha pathway to suppress experimental inflammatory bowel disease. Eur J Immunol. 2005;35:217-224.
16. Canning MO, Grotenhuis K, de Wit H, et al. 1-alpha, 25-dihydroxyVitamin D3 (1,25(OH)(2)D(3)) hampers the maturation of fully active immature dendritic cells from monocytes. Eur J Endocrinol. 2001;145:351-357.
17. Yusupov E, Li-Ng M, Pollack S, et al. Vitamin D and serum cytokines in a randomized clinical trial. Int J Endocrinol. 2010;2010:305054.
18. Liu N, Nguyen L, Chun RF, et al. Altered endocrine and autocrine metabolism of Vitamin D in a mouse model of gastrointestinal inflammation. Endocrinology. 2008;149: 4799-4808.
19. Burkiewicz CJ, Guadagnin FA, Skare TL, et al. Vitamin D and skin repair: a prospective, double-blind and placebo controlled study in the healing of leg ulcers [in English, Portuguese]. Rev Col Bras Cir. 2012;39:401-407.
20. Garcion E, Sindji L, Leblondel G, et al. 1,25-dihydroxyVitamin D3 regulates the synthesis of gamma-glutamyl transpeptidase and glutathione levels in rat primary astrocytes. J Neurochem. 1999;73:859-866.
21. Sardar S, Chakraborty A, Chatterjee M. Comparative effectiveness of Vitamin D3 and dietary Vitamin E on peroxidation of lipids and enzymes of the hepatic antioxidants system in Sprague-Dawley rats. Int J Vitam Nutr Res. 1996;66:39-45.
22. Horiuchi H, Nagata I, Komoriya K. Protective effect of Vitamin D3 analogues on endotoxin shock in mice. Agents Actions. 1991;33:343-348.
23. World Health Organisation. World Health Organisation Handbook for Reporting Results of Cancer Treatment. World Health Organisation Geneva, Switzerland; 1979:15-22.
24. Przepiorka D, Weisdorf D, Martin P, et al. 1994 Consensus Conference on Acute GVHD Grading. Bone Marrow Transplant. 1995;15:825-828.
25. Cahn JY, Klein JP, Lee SJ, et al. Prospective evaluation of 2 acute graft-versus-host (GVHD) grading systems: a joint Societe Françaisede Greffe de Moëlle et Therapie Cellulaire (SFGM-TC), Dana Farber Cancer Institute (DFCI), and International Bone Marrow Transplant Registry (IBMTR) prospective study. Blood. 2005;106: 1495-1500.
26. Moslehi A, Taghizadeh-Ghehi M, Gholami K, et al. N-acetyl cysteine for prevention of oral mucositis in hematopoietic SCT: a double-blind, randomized, placebocontrolled trial. Bone Marrow Transplant. 2014;49:818-823.
27. Jahangard-Rafsanjani Z, Gholami K, Hadjibabaie M, et al. The efficacy of selenium in prevention of oral mucositis in patients undergoing hematopoietic SCT: a randomized clinical trial. Bone Marrow Transplant. 2013;48: 832-836.
28. Fidler P, Loprinzi CL, O'Fallon JR, et al. Prospective evaluation of a chamomile mouthwash for prevention of 5-FU-Induced oral mucositis. Cancer. 1996;77:522-525.
29. Sonis ST. The pathobiology of mucositis. Nat Rev Cancer. 2004;4:277-284.
30. Spielberger R, Stiff P, Bensinger W, et al. Palifermin for oral mucositis after intensive therapy for hematologic cancers. N Engl J Med. 2004;351:2590-2598.
31. Dazzi C, Cariello A, Giovanis P, et al. Prophylaxis with GM-CSF mouthwashes does not reduce frequency and duration of severe oral mucositis in patients with solid tumors undergoing high-dose chemotherapy with autologous peripheral blood stem cell transplantation rescue: a double blind, randomized, placebo-controlled study. Ann Oncol. 2003;14:559-563.
32. van der Lelie H, Thomas BL, van Oers RH, et al. Effect of locally applied GM-CSF on OM after stem cell transplantation: a prospective placebo-controlled double-blind study. Ann Hematol. 2001;80:150-154.
33. Attal M, Huguet F, Rubie H, et al. Prevention of regimenrelated toxicities after bone marrow transplantation by pentoxifylline: a prospective, randomized trial. Blood. 1993;82:732-736.
34. Mansouri A, Hadjibabaie M, Iravani M, et al. The effect of zinc sulfate in the prevention of high-dose chemotherapy-induced mucositis: a double-blind, randomized, placebo-controlled study. Hematol Oncol. 2012;30:22-26.
35. Ye Y, Carlsson G, Agholme MB, et al. Pretherapeutic plasma pro-and anti-inflammatory mediators are related to high risk of oral mucositis in pediatric patients with acute leukemia: a prospective cohort study. PLoS One. 2013;8:1-7.
36. Gombart AF. The Vitamin D-antimicrobial peptide pathway and its role in protection against infection. Future Microbiol. 2009;4:1151-1165.
37. Schleithoff S, Zittermann A, Tenderich G, et al. Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a double-blind, randomized, placebo-controlled trial. Am J Clin Nutr. 2006;83: 754-759.