메뉴 건너뛰기




Volumn 2, Issue 2, 2006, Pages 159-168

Oral mucositis induced by anticancer treatments: Physiopathology and treatments

Author keywords

Chemotherapy; Oral mucositis; Palifermin; Radiotherapy

Indexed keywords

AES 14; ALKYLATING AGENT; AMIFOSTINE; AMPHOTERICIN B; ANTHRACYCLINE DERIVATIVE; ANTINEOPLASTIC AGENT; BENZYDAMINE; CARBOPLATIN; CHLORHEXIDINE; ETOPOSIDE; FLUOROURACIL; FOLINIC ACID; GLUTAMINE; GLUTAMINE DERIVATIVE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEMOPOIETIC GROWTH FACTOR; MELPHALAN; METHOTREXATE; NARCOTIC ANALGESIC AGENT; NEW DRUG; NONSTEROID ANTIINFLAMMATORY AGENT; PACLITAXEL; PALIFERMIN; PLACEBO; POLYMYXIN B; REPIFERMIN; TAXANE DERIVATIVE; TOBRAMYCIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 33745439040     PISSN: 11766336     EISSN: None     Source Type: Journal    
DOI: 10.2147/tcrm.2006.2.2.159     Document Type: Review
Times cited : (62)

References (83)
  • 1
    • 0032190220 scopus 로고    scopus 로고
    • Oral glutamine reduces the duration and severity of stomatitis after cytotoxic cancer chemotherapy
    • Anderson PM, Schroeder G, Skubitz KM. 1998. Oral glutamine reduces the duration and severity of stomatitis after cytotoxic cancer chemotherapy. Cancer, 83:1433-9.
    • (1998) Cancer , vol.83 , pp. 1433-1439
    • Anderson, P.M.1    Schroeder, G.2    Skubitz, K.M.3
  • 2
    • 0031694089 scopus 로고    scopus 로고
    • Effect of low-dose oral glutamine on painful stomatitis during bone marrow transplantation
    • Anderson PM, Ramsay NK, Shu XO, et al. 1998. Effect of low-dose oral glutamine on painful stomatitis during bone marrow transplantation. Bone Marrow Transplant, 22:339-44.
    • (1998) Bone Marrow Transplant , vol.22 , pp. 339-344
    • Anderson, P.M.1    Ramsay, N.K.2    Shu, X.O.3
  • 3
    • 0037203354 scopus 로고    scopus 로고
    • Sphingomyelin hydrolysis during apoptosis
    • Andriea-Abadic N, Levade T. 2002. Sphingomyelin hydrolysis during apoptosis. Biochem Biophys Acta, 1585:126-34.
    • (2002) Biochem Biophys Acta , vol.1585 , pp. 126-134
    • Andriea-Abadic, N.1    Levade, T.2
  • 4
    • 12344322268 scopus 로고    scopus 로고
    • Keratinocyte growth factor: Effects on keratinocytes and mechanisms of action
    • auf dem Keller U, Krampert M, Kümin A, et al. 2004 Keratinocyte growth factor: effects on keratinocytes and mechanisms of action. Eur J Biol, 83:607-12.
    • (2004) Eur J Biol , vol.83 , pp. 607-612
    • auf dem Keller, U.1    Krampert, M.2    Kümin, A.3
  • 5
    • 0033920730 scopus 로고    scopus 로고
    • Management of cancer in the older person: A practical approach
    • Balducci L, Exterrman M. 2000. Management of cancer in the older person: a practical approach. Oncologist, 20:224-37.
    • (2000) Oncologist , vol.20 , pp. 224-237
    • Balducci, L.1    Exterrman, M.2
  • 6
    • 0028867546 scopus 로고
    • Heliun-neon laser effects on conditioning-induced oral mucositis in bone marrow transplantation patients
    • Barasch A, Peterson DE, Tanzer JM, et al. 1995. Heliun-neon laser effects on conditioning-induced oral mucositis in bone marrow transplantation patients. Cancer, 76:2550-6.
    • (1995) Cancer , vol.76 , pp. 2550-2556
    • Barasch, A.1    Peterson, D.E.2    Tanzer, J.M.3
  • 7
    • 0036984990 scopus 로고    scopus 로고
    • Preliminary data of the GORTEC 2000-02 phase III trial comparing intravenous and subcutaneous administration of amifostine for head and neck tumors treated by external radiotherapy
    • Bardet E, Martin L, Calais G, et al. 2002. Preliminary data of the GORTEC 2000-02 phase III trial comparing intravenous and subcutaneous administration of amifostine for head and neck tumors treated by external radiotherapy. Sem Oncol, 29(suppl 19):57-60.
    • (2002) Sem Oncol , vol.29 , Issue.SUPPL. 19 , pp. 57-60
    • Bardet, E.1    Martin, L.2    Calais, G.3
  • 8
    • 0033952344 scopus 로고    scopus 로고
    • Patients reports of complications of bone marrow transplantation
    • Bellm LA, Epstein JB, Rose-Ped A, et al. 2000. Patients reports of complications of bone marrow transplantation. Support Care Cancer, 8:33-9.
    • (2000) Support Care Cancer , vol.8 , pp. 33-39
    • Bellm, L.A.1    Epstein, J.B.2    Rose-Ped, A.3
  • 9
    • 28344447809 scopus 로고    scopus 로고
    • Palifermin (A rHuKGF molecule) is safe and well tolerated in patients (Pts) with hematologic malignancies (HM) undergoing high-dose chemoradiotherapy (HD-CRT) followed by allogeneic hematopoietic stem cell transplant (HSCT)
    • [abstract]
    • Blazar BR, Weisdorf DJ, DeFor TE, et al. 2005. Palifermin (A rHuKGF molecule) is safe and well tolerated in patients (Pts) with hematologic malignancies (HM) undergoing high-dose chemoradiotherapy (HD-CRT) followed by allogeneic hematopoietic stem cell transplant (HSCT) [abstract]. Biol Blood Marrow Transplant, 11(suppl 1):11.
    • (2005) Biol Blood Marrow Transplant , vol.11 , Issue.SUPPL. 1 , pp. 11
    • Blazar, B.R.1    Weisdorf, D.J.2    DeFor, T.E.3
  • 10
    • 0036318224 scopus 로고    scopus 로고
    • Nrf2 transcription factor: A novel target of keratinocyte growth factor action regulates gene expression and inflammation in the healing skin wound
    • Braun S, Hanselmann C, Gassman MG, et al. 2002. Nrf2 transcription factor: a novel target of keratinocyte growth factor action regulates gene expression and inflammation in the healing skin wound. Mol Cell Biol, 22:5492-505.
    • (2002) Mol Cell Biol , vol.22 , pp. 5492-5505
    • Braun, S.1    Hanselmann, C.2    Gassman, M.G.3
  • 11
    • 0034305965 scopus 로고    scopus 로고
    • Phase III randomised trial of amifostine as a radioprotector in head and neck cancer
    • Brizel DM, Wasserman TH, Henke M, et al. 2000. Phase III randomised trial of amifostine as a radioprotector in head and neck cancer. J Clin Oncol, 18:3339-45.
    • (2000) J Clin Oncol , vol.18 , pp. 3339-3345
    • Brizel, D.M.1    Wasserman, T.H.2    Henke, M.3
  • 12
    • 0028107061 scopus 로고
    • Oral cooling (cryotherapy), an effective treatment for the prevention of 5-fluorouracil-induced stomatatis
    • Cascinu S, Fedeli A, Fedeli SL, et al. 1994. Oral cooling (cryotherapy), an effective treatment for the prevention of 5-fluorouracil-induced stomatatis. Eur J Cancer B Oral Oncol, 30B:234-6.
    • (1994) Eur J Cancer B Oral Oncol , vol.30 B , pp. 234-236
    • Cascinu, S.1    Fedeli, A.2    Fedeli, S.L.3
  • 13
    • 0028243039 scopus 로고
    • Regulation of keratinocyte growth factor gene expression by interleukin 1
    • Chedid M, Rubin JS, Csaky KG, et al. 1994. Regulation of keratinocyte growth factor gene expression by interleukin 1. J Biol Chem, 269:10753-7.
    • (1994) J Biol Chem , vol.269 , pp. 10753-10757
    • Chedid, M.1    Rubin, J.S.2    Csaky, K.G.3
  • 14
    • 0029121118 scopus 로고
    • Effect of granulocyte-macrophage colony-stimulating factor on oral mucositisin head and neck cancer patients after cisplatin, fluorouracil, and leucovorin chemotherapy
    • Chi KH, Chen CH, Chan WK, et al. 1995. Effect of granulocyte-macrophage colony-stimulating factor on oral mucositisin head and neck cancer patients after cisplatin, fluorouracil, and leucovorin chemotherapy. J Clin Oncol, 13:2620-8.
    • (1995) J Clin Oncol , vol.13 , pp. 2620-2628
    • Chi, K.H.1    Chen, C.H.2    Chan, W.K.3
  • 15
    • 0030755928 scopus 로고    scopus 로고
    • Low energy helium-neon laser in the prevention of oral mucositis in patients undergoing bone marrow transplan: Results of a double blind randomised trial
    • Cowen D, Tardieu C, Schubert M, et al. 1997. Low energy helium-neon laser in the prevention of oral mucositis in patients undergoing bone marrow transplan: results of a double blind randomised trial. Int J Radiot Oncol Biol Phys, 38:697-703.
    • (1997) Int J Radiot Oncol Biol Phys , vol.38 , pp. 697-703
    • Cowen, D.1    Tardieu, C.2    Schubert, M.3
  • 16
    • 0037481761 scopus 로고    scopus 로고
    • Prophylaxis with GM-CSF mouthwashes does not reduce frequency and duration of severe oral mucositis in patients with solid tumors undergoing high-dose chemotherapy with autologous peripheral blood stem cell transplantation rescue: A double blind randomised, placebo-controlled study
    • Dazzi C, Cariello A, Giovanis P, et al. 2003. Prophylaxis with GM-CSF mouthwashes does not reduce frequency and duration of severe oral mucositis in patients with solid tumors undergoing high-dose chemotherapy with autologous peripheral blood stem cell transplantation rescue: a double blind randomised, placebo-controlled study. Ann Oncol, 14:559-63.
    • (2003) Ann Oncol , vol.14 , pp. 559-563
    • Dazzi, C.1    Cariello, A.2    Giovanis, P.3
  • 17
    • 0038788959 scopus 로고    scopus 로고
    • Antimicrobial therapy to prevent or treat mucositis
    • Donnelly JP, Bellm LA, Epstein JB, et al. 2003. Antimicrobial therapy to prevent or treat mucositis. Lancet Infect Dis, 3:405-12.
    • (2003) Lancet Infect Dis , vol.3 , pp. 405-412
    • Donnelly, J.P.1    Bellm, L.A.2    Epstein, J.B.3
  • 18
    • 0032931689 scopus 로고    scopus 로고
    • Risk factors for chemotherapy-induced oral mucositis: Dental appliance, oral hygiene, previous oral lesions, and a history of smoking
    • Dood MJ, Miaskowski C, Shiba GH, et al. 1999. Risk factors for chemotherapy-induced oral mucositis: dental appliance, oral hygiene, previous oral lesions, and a history of smoking. Cancer Invest, 17:278-84.
    • (1999) Cancer Invest , vol.17 , pp. 278-284
    • Dood, M.J.1    Miaskowski, C.2    Shiba, G.H.3
  • 19
    • 0036718355 scopus 로고    scopus 로고
    • Amelioration of acute oral mucositis by keratinocyte growth factor: Fractionated irradiation
    • Dörr W, Spekl K, Farell C. 2002. Amelioration of acute oral mucositis by keratinocyte growth factor: fractionated irradiation. Int J Radiat Oncol Biol Phys, 54:245-51.
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , pp. 245-251
    • Dörr, W.1    Spekl, K.2    Farell, C.3
  • 20
  • 21
    • 0036652764 scopus 로고    scopus 로고
    • The role of salivary function in modulating chemotherapy-induced oropharyngeal mucositis: A review of the literature
    • Epstein JB, Tsang AHF, Warkentin D, et al. 2002. The role of salivary function in modulating chemotherapy-induced oropharyngeal mucositis: a review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 94:39-44.
    • (2002) Oral Surg Oral Med Oral Pathol Oral Radiol Endod , vol.94 , pp. 39-44
    • Epstein, J.B.1    Tsang, A.H.F.2    Warkentin, D.3
  • 22
    • 0032030965 scopus 로고    scopus 로고
    • Keratinocyte Growth Factor protects mice from chemotherapy and radiation-induced gastrointestinal injury and mortality
    • Farell CL, Bready JV, Rex KL, et al. 1998. Keratinocyte Growth Factor protects mice from chemotherapy and radiation-induced gastrointestinal injury and mortality. Cancer Res, 58:933-9.
    • (1998) Cancer Res , vol.58 , pp. 933-939
    • Farell, C.L.1    Bready, J.V.2    Rex, K.L.3
  • 23
    • 0024324070 scopus 로고
    • Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth
    • Finch PW, Rubin JS, Miki T, et al. 1989. Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth. Science, 245:752-5.
    • (1989) Science , vol.245 , pp. 752-755
    • Finch, P.W.1    Rubin, J.S.2    Miki, T.3
  • 24
    • 0028151447 scopus 로고
    • Randomized trial of chlorhexidine mouthwash for alleviation of radiation induced-mucositis
    • Foote RL, Loprinzi CL, Frank AR et al. 1994. Randomized trial of chlorhexidine mouthwash for alleviation of radiation induced-mucositis. J Clin Oncol, 12:2630-3.
    • (1994) J Clin Oncol , vol.12 , pp. 2630-2633
    • Foote, R.L.1    Loprinzi, C.L.2    Frank, A.R.3
  • 25
    • 11144235534 scopus 로고    scopus 로고
    • Phase I/II randomised clinical trial evaluating the safety and clinical effects of repifermin administered to reduce mucositis in patients undergoing autologous hemotopoietic stem cell transplantation
    • Freytes CO, Ratanathorn V, Taylor C, et al. 2004. Phase I/II randomised clinical trial evaluating the safety and clinical effects of repifermin administered to reduce mucositis in patients undergoing autologous hemotopoietic stem cell transplantation. Clin Cancer Res, 10:8318-24.
    • (2004) Clin Cancer Res , vol.10 , pp. 8318-8324
    • Freytes, C.O.1    Ratanathorn, V.2    Taylor, C.3
  • 26
    • 0030794485 scopus 로고    scopus 로고
    • Differential induction of pro- and anti-inflammatory cytokines in whole blood by bacteria effects of antibiotic treatment
    • Frieling JT, Mulder JA, Hendriks T, et al. 1997. Differential induction of pro- and anti-inflammatory cytokines in whole blood by bacteria effects of antibiotic treatment. Antimicrob Agents Chemother, 41:1439-43.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1439-1443
    • Frieling, J.T.1    Mulder, J.A.2    Hendriks, T.3
  • 27
    • 17844386336 scopus 로고    scopus 로고
    • Low level laser for prevention and therapy of oral mucositis induced by chemotherapy and/or radiotherapy
    • Genot MT, Klastersky J. 2005. Low level laser for prevention and therapy of oral mucositis induced by chemotherapy and/or radiotherapy. Curr Opin Oncol, 17:236-40.
    • (2005) Curr Opin Oncol , vol.17 , pp. 236-240
    • Genot, M.T.1    Klastersky, J.2
  • 28
    • 0026472433 scopus 로고
    • Studies of oral neutrophil levels in patients receiving G-CSF after autologous marrow transplantation
    • Graham GJ, Ramenghi U, O'Connor MP, et al. 1992. Studies of oral neutrophil levels in patients receiving G-CSF after autologous marrow transplantation. Br J Haematol, 82:589-95.
    • (1992) Br J Haematol , vol.82 , pp. 589-595
    • Graham, G.J.1    Ramenghi, U.2    O'Connor, M.P.3
  • 29
    • 8444232834 scopus 로고    scopus 로고
    • Saccharomyces Cerevisiae fumgemia in a head and neck cancer patient: A case report and review of the literature
    • Henry S, D'Hondt L, André M, et al. 2004. Saccharomyces Cerevisiae fumgemia in a head and neck cancer patient: a case report and review of the literature. Acta Clin Belg, 59:220-2.
    • (2004) Acta Clin Belg , vol.59 , pp. 220-222
    • Henry, S.1    D'Hondt, L.2    André, M.3
  • 30
    • 0037314968 scopus 로고    scopus 로고
    • Effect of keratinocyte growth factor on the proliferatio, clonogenic capacity and colony size of human epithelial tumour cells in vitro
    • Hille A, Rave-Frank M, Pradier O, et al. 2003. Effect of keratinocyte growth factor on the proliferatio, clonogenic capacity and colony size of human epithelial tumour cells in vitro. Int J Radiat Biol, 79:119-128.
    • (2003) Int J Radiat Biol , vol.79 , pp. 119-128
    • Hille, A.1    Rave-Frank, M.2    Pradier, O.3
  • 31
    • 0033596726 scopus 로고    scopus 로고
    • Heparin is essential for a single keratinocyte growth factor molecule to bind and form a complex with two molecules of the extracellular domain of its receptor
    • Hsu YR, Nybo R, Sullivan JK, et al. 1999. Heparin is essential for a single keratinocyte growth factor molecule to bind and form a complex with two molecules of the extracellular domain of its receptor. Biochemistry, 38:2523-34.
    • (1999) Biochemistry , vol.38 , pp. 2523-2534
    • Hsu, Y.R.1    Nybo, R.2    Sullivan, J.K.3
  • 32
    • 0036874221 scopus 로고    scopus 로고
    • Efficacy of Gelclair in reducing pain in palliative care patients with oral lesions: Preliminary findings from an open pilot study
    • Innocenti M, Moscatelli G, Lopez S. 2002. Efficacy of Gelclair in reducing pain in palliative care patients with oral lesions: preliminary findings from an open pilot study. J Pain Symptom Manage, 24:456-7.
    • (2002) J Pain Symptom Manage , vol.24 , pp. 456-457
    • Innocenti, M.1    Moscatelli, G.2    Lopez, S.3
  • 33
    • 0028169034 scopus 로고
    • 5-fluorouracil and folinic acid-induced mucositis: No effect of oral glutamine supplementation
    • Jebb SA, Osborne RJ, Maughan TS, et al. 1994. 5-fluorouracil and folinic acid-induced mucositis: no effect of oral glutamine supplementation. Br J Cancer, 70:732-5.
    • (1994) Br J Cancer , vol.70 , pp. 732-735
    • Jebb, S.A.1    Osborne, R.J.2    Maughan, T.S.3
  • 34
    • 0037387265 scopus 로고    scopus 로고
    • Keratinocyte growth factor (KGF) decreases ICAM-1 and VCAM-1 cell expression on bronchial epithelial cells
    • Just N, Tillie-Leblond I, Guery BP, et al. 2003. Keratinocyte growth factor (KGF) decreases ICAM-1 and VCAM-1 cell expression on bronchial epithelial cells. Clin Exp Immunol, 132:61-9.
    • (2003) Clin Exp Immunol , vol.132 , pp. 61-69
    • Just, N.1    Tillie-Leblond, I.2    Guery, B.P.3
  • 35
    • 0030973310 scopus 로고    scopus 로고
    • Efficacy and safety of granulocyte-macrophage colony-stimulating factor (GM-CSF) on the frequency and severity of radiation mucositis in patients with head and neck carcinoma
    • Kannan V, Bapsy PP, Anantha N et al. 1997. Efficacy and safety of granulocyte-macrophage colony-stimulating factor (GM-CSF) on the frequency and severity of radiation mucositis in patients with head and neck carcinoma. Int J Radiot Oncol Biol Phys, 37:1005-10.
    • (1997) Int J Radiot Oncol Biol Phys , vol.37 , pp. 1005-1010
    • Kannan, V.1    Bapsy, P.P.2    Anantha, N.3
  • 36
    • 0031794084 scopus 로고    scopus 로고
    • Effect of topical oral G-CSF on oral mucositis: A randomized placebo-controlled trial
    • Karthaus M, Rosenthal C, Huebner G, et al. 1998. Effect of topical oral G-CSF on oral mucositis: a randomized placebo-controlled trial. Bone Marrow Transplant, 22:781-5.
    • (1998) Bone Marrow Transplant , vol.22 , pp. 781-785
    • Karthaus, M.1    Rosenthal, C.2    Huebner, G.3
  • 37
    • 0036126385 scopus 로고    scopus 로고
    • Randomised phase III study of chemoradiation with or without amifostine for patients with favourable performance status inoperable stage II and III non-small cell lung cancer: Preliminary results
    • Komaki R, Lee JS, Kaplan B et al. 2002. Randomised phase III study of chemoradiation with or without amifostine for patients with favourable performance status inoperable stage II and III non-small cell lung cancer: preliminary results. Semin Radiot Oncol, 12(suppl 1):46-9.
    • (2002) Semin Radiot Oncol , vol.12 , Issue.SUPPL. 1 , pp. 46-49
    • Komaki, R.1    Lee, J.S.2    Kaplan, B.3
  • 38
    • 0037530506 scopus 로고    scopus 로고
    • Potential role of platelets in endothelial damage during treatment with gemcitabine and the angiogenesis inhibitor SU5416
    • Kuenen BC, Levi M, Meijers JC, et al. 2003. Potential role of platelets in endothelial damage during treatment with gemcitabine and the angiogenesis inhibitor SU5416. J Clin Oncol, 21:2192-8.
    • (2003) J Clin Oncol , vol.21 , pp. 2192-2198
    • Kuenen, B.C.1    Levi, M.2    Meijers, J.C.3
  • 39
    • 0031927762 scopus 로고    scopus 로고
    • The PRO-SELF mouth aware program: An effective approach for reducing chemotherapy-induced mucositis
    • Larson P, Miakowski C, MacPhail L, et al. 1998. The PRO-SELF mouth aware program: an effective approach for reducing chemotherapy-induced mucositis. Cancer Nurs, 21:263-8.
    • (1998) Cancer Nurs , vol.21 , pp. 263-268
    • Larson, P.1    Miakowski, C.2    MacPhail, L.3
  • 40
    • 17144417398 scopus 로고    scopus 로고
    • Randomized controlled trial of pilocarpine hydrochloride for the moderation of oral mucositis during autologous blood stem cell transplantation
    • Lockhart PB, Brennan MT, Kent ML, et al. 2005. Randomized controlled trial of pilocarpine hydrochloride for the moderation of oral mucositis during autologous blood stem cell transplantation. Bone Marrow Transplant, 35:713-20.
    • (2005) Bone Marrow Transplant , vol.35 , pp. 713-720
    • Lockhart, P.B.1    Brennan, M.T.2    Kent, M.L.3
  • 41
    • 0041700142 scopus 로고    scopus 로고
    • Phase III multicenter randomised trial of amifostine as cytoprotectant in first-line chemotherapy in ovarian cancer patients
    • Lorusso D, Ferrandina G, Greggi S, et al. 2003. Phase III multicenter randomised trial of amifostine as cytoprotectant in first-line chemotherapy in ovarian cancer patients. Ann Oncol, 14:1086-93.
    • (2003) Ann Oncol , vol.14 , pp. 1086-1093
    • Lorusso, D.1    Ferrandina, G.2    Greggi, S.3
  • 42
    • 0036239004 scopus 로고    scopus 로고
    • Keratinocyte growth factor (KGF) in haematology and oncology
    • MacDonald K, Hill G, 2002. Keratinocyte growth factor (KGF) in haematology and oncology. Curr Pharm Des, 8:395-403.
    • (2002) Curr Pharm Des , vol.8 , pp. 395-403
    • MacDonald, K.1    Hill, G.2
  • 43
    • 0026086871 scopus 로고
    • Inhibition of fluouracil-induced stomatatis by oral cryotherapy
    • Mahood DJ, Dose AM, Loprinzi CL, et al. 1991. Inhibition of fluouracil-induced stomatatis by oral cryotherapy. J Clin Oncol, 9:449-52.
    • (1991) J Clin Oncol , vol.9 , pp. 449-452
    • Mahood, D.J.1    Dose, A.M.2    Loprinzi, C.L.3
  • 44
    • 0033982779 scopus 로고    scopus 로고
    • Granulocyte macrophage-colony stimulating factor (GM-CSF) and sucralfate in prevention of radiation-induced mucositis: A prospective randomised study
    • Makkonen TA, Minn H, Jekunen A, et al. 2000. Granulocyte macrophage-colony stimulating factor (GM-CSF) and sucralfate in prevention of radiation-induced mucositis: a prospective randomised study. Int J Radiat Oncol Biol Phys, 46:525-34.
    • (2000) Int J Radiat Oncol Biol Phys , vol.46 , pp. 525-534
    • Makkonen, T.A.1    Minn, H.2    Jekunen, A.3
  • 45
    • 0032997649 scopus 로고    scopus 로고
    • The effect of granulocyte colony-stimulating factor on oral mucositisin head and neck cancer patients treated with hyperfractionated radiotherapy
    • Mascarin M, Franchin G, Minatel E, et al. 1999. The effect of granulocyte colony-stimulating factor on oral mucositisin head and neck cancer patients treated with hyperfractionated radiotherapy. Oral Oncol, 35:203-8.
    • (1999) Oral Oncol , vol.35 , pp. 203-208
    • Mascarin, M.1    Franchin, G.2    Minatel, E.3
  • 46
    • 0027396854 scopus 로고
    • Radiation-induced increased platelet-activating factor activity in mixed saliva
    • McManus LM, Ostrom KK, Laer C, et al. 1993. Radiation-induced increased platelet-activating factor activity in mixed saliva. Lab Invest, 68:118-24.
    • (1993) Lab Invest , vol.68 , pp. 118-124
    • McManus, L.M.1    Ostrom, K.K.2    Laer, C.3
  • 47
    • 0345596364 scopus 로고    scopus 로고
    • Toxicity of fluorouracil in patients with advanced colorectal cancer: Effect of administration schedule and prognostic factors
    • [MAC] Meta-Analysis Group in Cancer. Meta-Analysis Group in Cancer
    • [MAC] Meta-Analysis Group in Cancer. 1998. Toxicity of fluorouracil in patients with advanced colorectal cancer: effect of administration schedule and prognostic factors. Meta-Analysis Group in Cancer. J Clin Oncol, 16:3537-41.
    • (1998) J Clin Oncol , vol.16 , pp. 3537-3541
  • 48
    • 0037842184 scopus 로고    scopus 로고
    • Randomized phase I trial of recombinant human keratinocyte growth factor plus chemotherapy: Potential role as mucosal protectant
    • Meropol NJ, Somer RA, Gutheil J, et al. 2003. Randomized phase I trial of recombinant human keratinocyte growth factor plus chemotherapy: potential role as mucosal protectant. J Clin Oncol, 21:1452-8.
    • (2003) J Clin Oncol , vol.21 , pp. 1452-1458
    • Meropol, N.J.1    Somer, R.A.2    Gutheil, J.3
  • 49
    • 1542440362 scopus 로고    scopus 로고
    • The development of supportive-care agents for patients with cancer
    • Neumann TK, Foote MA. 2003. The development of supportive-care agents for patients with cancer. Biotechn Ann Rev, 9:397-416.
    • (2003) Biotechn Ann Rev , vol.9 , pp. 397-416
    • Neumann, T.K.1    Foote, M.A.2
  • 50
    • 16644378853 scopus 로고    scopus 로고
    • Influence of keratinocyte growth factor on clonal growth of epithelial cells, lymphoma and leukaemia cells and on sensitivity of tumor cells towards 5-fluorouracil in vitro
    • Oelmann E, Haghu S, Kulimova E, et al. 2004. Influence of keratinocyte growth factor on clonal growth of epithelial cells, lymphoma and leukaemia cells and on sensitivity of tumor cells towards 5-fluorouracil in vitro. Int J Oncol, 25:1001-12.
    • (2004) Int J Oncol , vol.25 , pp. 1001-1012
    • Oelmann, E.1    Haghu, S.2    Kulimova, E.3
  • 51
    • 0033512244 scopus 로고    scopus 로고
    • Phase III controlled evaluation of glutamine for decreasing stomatatis in patients receiving fluorouracil (5-FU)-based chemotherapy
    • Okuno SH, Woodhouse CO, Loprinzi CL, et al. 1999. Phase III controlled evaluation of glutamine for decreasing stomatatis in patients receiving fluorouracil (5-FU)-based chemotherapy. Am J Clin Oncol, 22:258-61.
    • (1999) Am J Clin Oncol , vol.22 , pp. 258-261
    • Okuno, S.H.1    Woodhouse, C.O.2    Loprinzi, C.L.3
  • 52
    • 0034672365 scopus 로고    scopus 로고
    • Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury
    • Panoskaltsis-Mortari A, Taylor PA, Rubin JS, et al. 2000. Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury. Blood, 96:4350-6.
    • (2000) Blood , vol.96 , pp. 4350-4356
    • Panoskaltsis-Mortari, A.1    Taylor, P.A.2    Rubin, J.S.3
  • 53
    • 0034076350 scopus 로고    scopus 로고
    • KGF pretreatment decreases B7 and granzyme B expression and hastens repair in lungs of mice after allogeneic BMT
    • Panoskaltsis-Mortari A, Ingbar DH, Jung P, et al. 2000. KGF pretreatment decreases B7 and granzyme B expression and hastens repair in lungs of mice after allogeneic BMT. Am J Physiol Lung Cell Mol Physiol, 278:988-99.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.278 , pp. 988-999
    • Panoskaltsis-Mortari, A.1    Ingbar, D.H.2    Jung, P.3
  • 54
    • 0035225889 scopus 로고    scopus 로고
    • Mucositis in head and neck cancer: Economic and quality-of-life outcomes
    • Peterman A, Cella D, Glandon G, et al. 2001. Mucositis in head and neck cancer: economic and quality-of-life outcomes. J Natl Cancer Inst Monogr, 29:45-51.
    • (2001) J Natl Cancer Inst Monogr , vol.29 , pp. 45-51
    • Peterman, A.1    Cella, D.2    Glandon, G.3
  • 55
    • 3042759701 scopus 로고    scopus 로고
    • Mucosal damage: A major risk factor for severe complications after cytotoxic therapy
    • Peterson DE, Cariello A. 2004. Mucosal damage: a major risk factor for severe complications after cytotoxic therapy. Sem Oncol, 31:35-44.
    • (2004) Sem Oncol , vol.31 , pp. 35-44
    • Peterson, D.E.1    Cariello, A.2
  • 57
    • 0037822160 scopus 로고    scopus 로고
    • Do cancer patients with chemotherapy-induced leukopenia benefit from an antiseptic chlorhexidine-based oral rinse? A double-blind, block-randomised, controlled study
    • Pitten FA, Kiefer T, Buth C, et al. 2003. Do cancer patients with chemotherapy-induced leukopenia benefit from an antiseptic chlorhexidine-based oral rinse? A double-blind, block-randomised, controlled study. J Hosp Infect, 53:283-91.
    • (2003) J Hosp Infect , vol.53 , pp. 283-291
    • Pitten, F.A.1    Kiefer, T.2    Buth, C.3
  • 58
    • 0032792959 scopus 로고    scopus 로고
    • Adjuvant or palliative chemotherapy for colorectal cancerin patients 70 years or older
    • Popescu RA, Norman A, Ross PJ, et al. 1999. Adjuvant or palliative chemotherapy for colorectal cancerin patients 70 years or older. J Clin Oncol, 17:2412-8.
    • (1999) J Clin Oncol , vol.17 , pp. 2412-2418
    • Popescu, R.A.1    Norman, A.2    Ross, P.J.3
  • 59
    • 0036957456 scopus 로고    scopus 로고
    • Standardized parenteral alanyl-glutamine dipeptide supplementation is not beneficial in autologous transplant patients: A randomised, double-blind placebo controlled study
    • Pytlik R, Benes P, Patorkova M et al. 2002. Standardized parenteral alanyl-glutamine dipeptide supplementation is not beneficial in autologous transplant patients: a randomised, double-blind placebo controlled study. Bone Marrow Transplant, 30:953-61.
    • (2002) Bone Marrow Transplant , vol.30 , pp. 953-961
    • Pytlik, R.1    Benes, P.2    Patorkova, M.3
  • 60
    • 6944229503 scopus 로고    scopus 로고
    • Chemotherapy-induced and/or radiation therapy-induced oral mucositis-complicating the treatment of cancer
    • Rao Naidu MU, Venkat Ramana G, Usha Rani P, et al. 2004. Chemotherapy-induced and/or radiation therapy-induced oral mucositis-complicating the treatment of cancer. Neoplasia, 6:423-31.
    • (2004) Neoplasia , vol.6 , pp. 423-431
    • Rao Naidu, M.U.1    Venkat Ramana, G.2    Usha Rani, P.3
  • 61
    • 18744392950 scopus 로고    scopus 로고
    • Keratinocyte Growth Factor (Palifermin) in combination with tacrolimus and methotrexate for the prevention of acute graft-vs-host disease (aGvHD) in patients at high risk of a GvHD
    • [abstract]
    • Reynolds CM, Levine JE, Uberti JP, et al. 2004. Keratinocyte Growth Factor (Palifermin) in combination with tacrolimus and methotrexate for the prevention of acute graft-vs-host disease (aGvHD) in patients at high risk of a GvHD [abstract]. Blood, 104:1228.
    • (2004) Blood , vol.104 , pp. 1228
    • Reynolds, C.M.1    Levine, J.E.2    Uberti, J.P.3
  • 62
    • 0031766789 scopus 로고    scopus 로고
    • Amphotericin B activation of human genes encoding for cytokines
    • Rogers PD, Jenkins JK, Chapman SW, et al. 1998. Amphotericin B activation of human genes encoding for cytokines. J Infect Dis, 178:1726-33.
    • (1998) J Infect Dis , vol.178 , pp. 1726-1733
    • Rogers, P.D.1    Jenkins, J.K.2    Chapman, S.W.3
  • 63
    • 11144356601 scopus 로고    scopus 로고
    • Clinical practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis
    • Rubenstein EB, Peterson DE, Schubert M, et al. 2004. Clinical practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis. Cancer, 100:2026-46.
    • (2004) Cancer , vol.100 , pp. 2026-2046
    • Rubenstein, E.B.1    Peterson, D.E.2    Schubert, M.3
  • 64
    • 0001088219 scopus 로고
    • Purification and characterization of a newly identified growth factor specific for epithelial cells
    • Rubin JS, Osada H, Finch PW, et al. 1989. Purification and characterization of a newly identified growth factor specific for epithelial cells. Proc Natl Acad Sci USA, 86:802-6.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 802-806
    • Rubin, J.S.1    Osada, H.2    Finch, P.W.3
  • 65
    • 16344389534 scopus 로고    scopus 로고
    • Chemotherapy and radiotherapy-induced oral mucositis: Review of perspective strategies and treatment
    • Saadeh CE. 2005. Chemotherapy and radiotherapy-induced oral mucositis: review of perspective strategies and treatment. Pharmacotherapy, 25:540-54.
    • (2005) Pharmacotherapy , vol.25 , pp. 540-554
    • Saadeh, C.E.1
  • 66
    • 13344294983 scopus 로고    scopus 로고
    • Management of chemotherapy-induced nausea, vomiting, oral mucositis, and diarrhoea
    • Sharma R, Tobin P, Clarke SJ. 2005. Management of chemotherapy-induced nausea, vomiting, oral mucositis, and diarrhoea. Lancet Oncol, 6:93-102.
    • (2005) Lancet Oncol , vol.6 , pp. 93-102
    • Sharma, R.1    Tobin, P.2    Clarke, S.J.3
  • 67
    • 0030087912 scopus 로고    scopus 로고
    • Oral glutamine to prevent chemotherapy induced stomatatis: A pilot study
    • Skubitz KM, Anderson PM. 1996. Oral glutamine to prevent chemotherapy induced stomatatis: a pilot study. J Lab Clin Med, 127:223-8.
    • (1996) J Lab Clin Med , vol.127 , pp. 223-228
    • Skubitz, K.M.1    Anderson, P.M.2
  • 68
    • 11144356545 scopus 로고    scopus 로고
    • Perspectives on cancer therapy-induced mucosal injury. Pathogenesis, measurement, epidemiology, and consequences for patients
    • Sonis ST, Elting LS, Keefe D, et al. 2004. Perspectives on cancer therapy-induced mucosal injury. Pathogenesis, measurement, epidemiology, and consequences for patients. Cancer, 100:1995-2025.
    • (2004) Cancer , vol.100 , pp. 1995-2025
    • Sonis, S.T.1    Elting, L.S.2    Keefe, D.3
  • 69
    • 5144229908 scopus 로고    scopus 로고
    • A biological approach to mucositis
    • Sonis ST. 2004. A biological approach to mucositis. J Support Oncol, 2:21-36.
    • (2004) J Support Oncol , vol.2 , pp. 21-36
    • Sonis, S.T.1
  • 70
    • 0031944107 scopus 로고    scopus 로고
    • Mucositis as a biologic process: A new hypothesis for the development of chemotherapy-induced stomatotoxicity
    • Sonis ST. 1998. Mucositis as a biologic process: a new hypothesis for the development of chemotherapy-induced stomatotoxicity. Oral Oncol, 34:39-43.
    • (1998) Oral Oncol , vol.34 , pp. 39-43
    • Sonis, S.T.1
  • 71
    • 0036044091 scopus 로고    scopus 로고
    • The biologic role for nuclear factor-kappaB in disease and its potential involvement in mucosal injury associated with anti-neoplasic therapy
    • Sonis ST. 2002. The biologic role for nuclear factor-kappaB in disease and its potential involvement in mucosal injury associated with anti-neoplasic therapy. Crit Rev Oral Biol Med, 13:380-9.
    • (2002) Crit Rev Oral Biol Med , vol.13 , pp. 380-389
    • Sonis, S.T.1
  • 72
    • 21044451567 scopus 로고    scopus 로고
    • Prospective randomised trial of amifostine cytoprotection in myeloma patients undergoing high-dose melphalan conditioned autologous stem cell transplantation
    • Spencer A, Horvath N, Gibson J, et al. 2005. Prospective randomised trial of amifostine cytoprotection in myeloma patients undergoing high-dose melphalan conditioned autologous stem cell transplantation. Bone Marrow Transplant, 35:971-7.
    • (2005) Bone Marrow Transplant , vol.35 , pp. 971-977
    • Spencer, A.1    Horvath, N.2    Gibson, J.3
  • 73
    • 10344242939 scopus 로고    scopus 로고
    • Palifermin for oral mucositis after intensive therapy for hematologic cancers
    • Spielberger R, Stiff P, Bensinger W, et al. 2004. Palifermin for oral mucositis after intensive therapy for hematologic cancers. N Engl J Med, 351:10-18.
    • (2004) N Engl J Med , vol.351 , pp. 10-18
    • Spielberger, R.1    Stiff, P.2    Bensinger, W.3
  • 74
    • 0034176245 scopus 로고    scopus 로고
    • Common toxicity criteria: Version 2.0. An improved reference for grading the acute effects of cancer treatment: Impact on radiotherapy
    • Trotti A, Byhardt R, Stetz J, et al. 2000. Common toxicity criteria: version 2.0. An improved reference for grading the acute effects of cancer treatment: impact on radiotherapy. Int J Radiat Oncol Biol Phys, 47:13-47.
    • (2000) Int J Radiat Oncol Biol Phys , vol.47 , pp. 13-47
    • Trotti, A.1    Byhardt, R.2    Stetz, J.3
  • 75
    • 0035412398 scopus 로고    scopus 로고
    • Pharmacogenetics of methotrexate toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism
    • Ulrich CM, Yasui Y, Storb R, et al. 2001. Pharmacogenetics of methotrexate toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism. Blood, 98:231-4.
    • (2001) Blood , vol.98 , pp. 231-234
    • Ulrich, C.M.1    Yasui, Y.2    Storb, R.3
  • 76
    • 27844494816 scopus 로고    scopus 로고
    • Keratinocyte growth factor ameliorates acute graft-versus-host disease in a novel nonmyeloablative haploidentical transplantation model
    • Vanclée A, Lutgens LC, Oving EB, et al. 2005. Keratinocyte growth factor ameliorates acute graft-versus-host disease in a novel nonmyeloablative haploidentical transplantation model. Bone Marrow Transplant, 36:907-15.
    • (2005) Bone Marrow Transplant , vol.36 , pp. 907-915
    • Vanclée, A.1    Lutgens, L.C.2    Oving, E.B.3
  • 77
    • 0036149561 scopus 로고    scopus 로고
    • Short-term inhibition of ADP-induced platelet aggregation by clopidrogel ameliorates radiation-induced toxicity in rat small intestine
    • Wang J, Albertson CM, Zheng H, et al. 2002. Short-term inhibition of ADP-induced platelet aggregation by clopidrogel ameliorates radiation-induced toxicity in rat small intestine. Thromb Haemost, 87:122-8.
    • (2002) Thromb Haemost , vol.87 , pp. 122-128
    • Wang, J.1    Albertson, C.M.2    Zheng, H.3
  • 78
    • 0033836189 scopus 로고    scopus 로고
    • Prospective evaluation of oral mucositis in patients receiving myeloablative conditioning regimens and hematopoietic progenitor rescue
    • Wardley AM, Jayson GC, Swindell R, et al. 2000. Prospective evaluation of oral mucositis in patients receiving myeloablative conditioning regimens and hematopoietic progenitor rescue. Br J Haematol, 110:292-9.
    • (2000) Br J Haematol , vol.110 , pp. 292-299
    • Wardley, A.M.1    Jayson, G.C.2    Swindell, R.3
  • 79
    • 0031784237 scopus 로고    scopus 로고
    • Prevention and treatment of oral mucositis following cancer chemotherapy
    • Wilkes JD. 1998. Prevention and treatment of oral mucositis following cancer chemotherapy. Sem Oncol, 25:538-51.
    • (1998) Sem Oncol , vol.25 , pp. 538-551
    • Wilkes, J.D.1
  • 80
    • 0003527864 scopus 로고    scopus 로고
    • [WHO] World Health Organization. (2nd ed). Genova, Italy: WHO
    • [WHO] World Health Organization. 1996. Cancer pain relief (2nd ed). Genova, Italy: WHO
    • (1996) Cancer Pain Relief
  • 81
    • 20944450198 scopus 로고    scopus 로고
    • Chemotherapy-induced oral mucositis: New approaches to prevention and management
    • Wright J, Feld R, Knox J. 2005. Chemotherapy-induced oral mucositis: new approaches to prevention and management. Exp Opin Drug Saf, 4:193-200.
    • (2005) Exp Opin Drug Saf , vol.4 , pp. 193-200
    • Wright, J.1    Feld, R.2    Knox, J.3
  • 82
    • 0030757661 scopus 로고    scopus 로고
    • A new in vitro assay of quantitation of chemotherapy induced mucositis
    • Wymenga AN, van der Graaf WT, Spijkervet FK, et al. 1997. A new in vitro assay of quantitation of chemotherapy induced mucositis. Br J Cancer, 8:1062-6.
    • (1997) Br J Cancer , vol.8 , pp. 1062-1066
    • Wymenga, A.N.1    van der Graaf, W.T.2    Spijkervet, F.K.3
  • 83
    • 0033052122 scopus 로고    scopus 로고
    • Phase I study of transforming growth factor-beta 3 mouthwashes for prevention of chemotherapy induced mucositis
    • Wymenga AN, van der Graaf WT, Hofstra LS, et al. 1999. Phase I study of transforming growth factor-beta 3 mouthwashes for prevention of chemotherapy induced mucositis. Clin Cancer Res, 5:1363-8.
    • (1999) Clin Cancer Res , vol.5 , pp. 1363-1368
    • Wymenga, A.N.1    van der Graaf, W.T.2    Hofstra, L.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.