Effect of locally applied GM-CSF on oral mucositis after stem cell transplantation: A prospective placebo-controlled double-blind study

Annals of Hematology

Volumn 80, Issue 3, 2001, Pages 150-154

  van der Lelie, Hans ^a   Thomas, Ber L M ^a   van Oers, Rien H J ^a   Ek Post, Mineke ^a   Sjamsoedin, Sjam A S ^a   van Dijk Overtoom, Marjolein L ^a   Timmer, John G ^a   von dem Borne, Albert E G K ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

GM CSF; Mucositis; Stem cell transplantation

Indexed keywords

AMPHOTERICIN B; ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; BUSULFAN; CARMUSTINE; CIPROFLOXACIN; CYCLOPHOSPHAMIDE; CYTARABINE; ETOPOSIDE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MELPHALAN; METHYLCELLULOSE; MORPHINE; MYELOABLATIVE AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; PENICILLIN G; PLACEBO; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

ACUTE LEUKEMIA; ADULT; ALLOGENIC BONE MARROW TRANSPLANTATION; ANTIBIOTIC PROPHYLAXIS; ARTICLE; AUTOTRANSPLANTATION; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; FEVER; FOOD INTAKE; GEL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HOSPITALIZATION; HUMAN; INCIDENCE; INFECTION; LYMPHOMA; MALE; MOUTH DISEASE; MUCOSA INFLAMMATION; MULTIPLE MYELOMA; NEUTROPENIA; PAIN; PARENTERAL NUTRITION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SCORING SYSTEM; WHOLE BODY RADIATION; WORLD HEALTH ORGANIZATION;

ADMINISTRATION, TOPICAL; ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; DOUBLE-BLIND METHOD; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MALE; MIDDLE AGED; MOUTH MUCOSA; MYELOABLATIVE AGONISTS; PROSPECTIVE STUDIES; STOMATITIS;

EID: 0035057175     PISSN: 09395555     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002770000264     Document Type: Article

References (17)

1. Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor induce human endothelial cells to migrate and proliferate
2. Evaluation of GM-CSF mouthwash for prevention of chemotherapy induced mucositis: A randomised, double-blind dose-ranging study
3. Development, testing and application of the oral assessment guide
4. Granulocyte-macrophage colony stimulating-factor improves survival in two models of gut-derived sepsis by improving gut barrier function and modulating bacterial clearance
5. Effect of granulocyte-macrophage colony-stimulating factor on chemotherapy-induced oral mucositis in non-neutropenic cancer patients
6. Granulocyte-macrophage-stimulating factor and granulocyte colony-stimulating factor: Differential action on incisional wound healing
7. Efficacy and safety of granulocyte macrophage-colony stimulating factor (GM-CSF) on the frequency and severity of radiation mucositis in patients with head and neck carcinoma
8. Effect of topical oral G-CSF on oral mucositis: A randomised placebo-controlled trial
9. Prophylaxis and treatment of chemo- and radiotherapy-induced oral mucositis - Are there new strategies?
10. Effect of granulocyte colony-stimulating factor (G-CSF) on chemotherapy-induced oral mucositis
11. Effect of granulocyte macrophage colony stimulating factor on oral mucositis in head and neck cancer patients after cisplatin, fluorouracil, and leukovorin chemotherapy
12. Studies of oral neutrophil levels in patients receiving G-CSF after autologous marrow transplantation
13. A pilot study of the effect of granulocyte-macrophage colony-stimulating factor on oral mucositis in head and neck cancer patients during X-radiation therapy: A preliminary report
14. Effect of granulocyte-macrophage colony-stimulating factor on prevention of mucositis in head and neck cancer patients treated with chemo-radiotherapy
15. Clinical assessment scale for the rating of oral mucosal changes associated with bone marrow transplantation
16. Effect of granulocyte macrophage colony stimulating factor on oral mucositis after hematopoietic stem-cell transplantation
17. Prevention and treatment of oral mucositis following cancer chemotherapy