Zein nanoparticles for oral delivery of quercetin: Pharmacokinetic studies and preventive anti-inflammatory effects in a mouse model of endotoxemia

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 13, Issue 1, 2017, Pages 103-110

  Penalva, Rebeca ^a   González Navarro, Carlos J ^a   Gamazo, Carlos ^a   Esparza, Irene ^a   Irache, Juan M ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Cyclodextrin; Nanoparticles; Oral delivery; Quercetin; Sepsis

Indexed keywords

ANIMALS; BIOCHEMISTRY; CYCLODEXTRINS; FLAVONOIDS; MAMMALS; PHENOLS;

ANTI-INFLAMMATORY EFFECTS; ORAL ADMINISTRATION; ORAL BIOAVAILABILITIES; ORAL DELIVERY; PHARMACOKINETIC STUDIES; QUERCETIN; SEPSIS; ZERO ORDER KINETICS;

NANOPARTICLES;

2 HYDROXYPROPYL BETA CYCLODEXTRIN; FLAVONOID; NANOPARTICLE; QUERCETIN; TUMOR NECROSIS FACTOR; ZEIN; ANTIINFLAMMATORY AGENT; DRUG CARRIER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; ENCAPSULATION; ENDOTOXEMIA; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; PARTICLE SIZE; PHARMACOKINETIC PARAMETERS; PHYSICAL CHEMISTRY; RAT; ANIMAL; BLOOD; C57BL MOUSE; CHEMISTRY; ORAL DRUG ADMINISTRATION; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; DRUG CARRIERS; ENDOTOXEMIA; MICE; MICE, INBRED C57BL; NANOPARTICLES; QUERCETIN; RATS, WISTAR; TUMOR NECROSIS FACTOR-ALPHA; ZEIN;

EID: 84995695128     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2016.08.033     Document Type: Article

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