Early Mobilization and Rehabilitation of Patients Who Are Critically Ill

Chest

Volumn 150, Issue 3, 2016, Pages 722-731

  Hashem, Mohamed D ^a,b   Parker, Ann M ^a,b   Needham, Dale M ^a,b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

early mobilization; ICU; physical therapy; rehabilitation

Indexed keywords

CORTICOSTEROID; NEUROMUSCULAR BLOCKING AGENT;

ARTIFICIAL VENTILATION; BED REST; CATHETER; CONTINUOUS RENAL REPLACEMENT THERAPY; CRITICAL ILLNESS MYOPATHY; CRITICAL ILLNESS POLYNEUROPATHY; CRITICALLY ILL PATIENT; CULTURAL ANTHROPOLOGY; DELIRIUM; FEMORAL CATHETER; FUNCTIONAL DISEASE; HEALTH CARE COST; HUMAN; INDEPENDENCE; INTENSIVE CARE UNIT ACQUIRED WEAKNESS; LENGTH OF STAY; MOBILIZATION; NEUROMUSCULAR DISEASE; PRIORITY JOURNAL; REHABILITATION CARE; REVIEW; SAFETY; SEDATION; CRITICAL ILLNESS; INTENSIVE CARE UNIT; MUSCULAR DISEASES; PHYSIOTHERAPY; POLYNEUROPATHIES; RISK FACTOR;

ADRENAL CORTEX HORMONES; BED REST; CRITICAL ILLNESS; EARLY AMBULATION; HUMANS; INTENSIVE CARE UNITS; MUSCULAR DISEASES; NEUROMUSCULAR BLOCKING AGENTS; PHYSICAL THERAPY MODALITIES; POLYNEUROPATHIES; RISK FACTORS;

EID: 84995578307     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1016/j.chest.2016.03.003     Document Type: Review

References (86)

1. 1 Bolton, C.F., Gilbert, J.J., Hahn, A.F., Sibbald, W.J., Polyneuropathy in critically ill patients. J Neurol Neurosurg Psychiatry 47:11 (1984), 1223–1231.
2. 2 Zochodne, D.W., Bolton, C.F., Wells, G.A., et al. Critical illness polyneuropathy: a complication of sepsis and multiple organ failure. Brain J Neurol 110:pt 4 (1987), 819–841.
3. 3 De Jonghe, B., Sharshar, T., Lefaucheur, J.P., et al. Paresis acquired in the intensive care unit: a prospective multicenter study. JAMA 288:22 (2002), 2859–2867.
4. 4 Batt, J., dos Santos, C.C., Cameron, J.I., Herridge, M.S., Intensive care unit-acquired weakness: clinical phenotypes and molecular mechanisms. Am J Respir Crit Care Med 187:3 (2013), 238–246.
5. 5 Fenzi, F., Latronico, N., Refatti, N., Rizzuto, N., Enhanced expression of E-selectin on the vascular endothelium of peripheral nerve in critically ill patients with neuromuscular disorders. Acta Neuropathol (Berl) 106:1 (2003), 75–82.
6. 6 Danon, M.J., Carpenter, S., Myopathy with thick filament (myosin) loss following prolonged paralysis with vecuronium during steroid treatment. Muscle Nerve 14:11 (1991), 1131–1139.
7. 7 Puthucheary, Z.A., Rawal, J., McPhail, M., et al. Acute skeletal muscle wasting in critical illness. JAMA 310:15 (2013), 1591–1600.
8. 8 Stevens, R.D., Marshall, S.A., Cornblath, D.R., et al. A framework for diagnosing and classifying intensive care unit-acquired weakness. Crit Care Med 37:10 suppl (2009), S299–S308.
9. 9 Latronico, N., Fenzi, F., Recupero, D., et al. Critical illness myopathy and neuropathy. Lancet 347:9015 (1996), 1579–1582.
10. 10 Appleton, R.T., Kinsella, J., Quasim, T., The incidence of intensive care unit-acquired weakness syndromes: a systematic review. J Intensive Care Soc 16:2 (2015), 126–136.
11. 11 Kress, J.P., Hall, J.B., ICU-acquired weakness and recovery from critical illness. N Engl J Med 370:17 (2014), 1626–1635.
12. 12 Kleyweg, R.P., van der Meché, F.G., Schmitz, P.I., Interobserver agreement in the assessment of muscle strength and functional abilities in Guillain-Barré syndrome. Muscle Nerve 14:11 (1991), 1103–1109.
13. 13 Hermans, G., De Jonghe, B., Bruyninckx, F., Van den Berghe, G., Clinical review: critical illness polyneuropathy and myopathy. Crit Care, 12(6), 2008, 238.
14. 14 Ali, N.A., O'Brien, J.M., Hoffmann, S.P., et al. Acquired weakness, handgrip strength, and mortality in critically ill patients. Am J Respir Crit Care Med 178:3 (2008), 261–268.
15. 15 Vanpee, G., Hermans, G., Segers, J., Gosselink, R., Assessment of limb muscle strength in critically ill patients: a systematic review. Crit Care Med 42:3 (2014), 701–711.
16. 16 Baldwin, C.E., Paratz, J.D., Bersten, A.D., Muscle strength assessment in critically ill patients with handheld dynamometry: an investigation of reliability, minimal detectable change, and time to peak force generation. J Crit Care 28:1 (2013), 77–86.
17. 17 Jones, S.W., Hill, R.J., Krasney, P.A., O'Conner, B., Peirce, N., Greenhaff, P.L., Disuse atrophy and exercise rehabilitation in humans profoundly affects the expression of genes associated with the regulation of skeletal muscle mass. FASEB J 18:9 (2004), 1025–1027.
18. 18 Suetta, C., Hvid, L.G., Justesen, L., et al. Effects of aging on human skeletal muscle after immobilization and retraining. J Appl Physiol. 1985 107:4 (2009), 1172–1180.
19. 19 Fan, E., Dowdy, D.W., Colantuoni, E., et al. Physical complications in acute lung injury survivors: a two-year longitudinal prospective study. Crit Care Med 42:4 (2014), 849–859.
20. 20 Needham, D.M., Wozniak, A.W., Hough, C.L., et al. Risk factors for physical impairment after acute lung injury in a national, multicenter study. Am J Respir Crit Care Med 189:10 (2014), 1214–1224.
21. 21 Berney, S.C., Harrold, M., Webb, S.A., et al. Intensive care unit mobility practices in Australia and New Zealand: a point prevalence study. Crit Care Resusc 15:4 (2013), 260–265.
22. 22 Nydahl, P., Ruhl, A.P., Bartoszek, G., et al. Early mobilization of mechanically ventilated patients: a 1-day point-prevalence study in Germany. Crit Care Med 42:5 (2014), 1178–1186.
23. 23 Jolley SE, Moss M, Needham DM, et al. Point prevalence study of intensive care unit mobility across the acute respiratory distress syndrome network [abstract]. In: Moving the Needle on ICU-associated Neuromuscular Weakness. American Thoracic Society; Am J Respir Crit Care Med. 2015. A6349.
24. 24 Ware, J.E. Jr., Sherbourne, C.D., The M.O.S. 36-item short-form health survey (SF-36). I Conceptual framework and item selection. Medical Care 30:6 (1992), 473–483.
25. 25 Hermans, G., Wilmer, A., Meersseman, W., et al. Impact of intensive insulin therapy on neuromuscular complications and ventilator dependency in the medical intensive care unit. Am J Respir Crit Care Med 175:5 (2007), 480–489.
26. 26 Papazian, L., Forel, J.M., Gacouin, A., et al. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 363:12 (2010), 1107–1116.
27. 27 De Jonghe, B., Bastuji-Garin, S., Sharshar, T., Outin, H., Brochard, L., Does ICU-acquired paresis lengthen weaning from mechanical ventilation?. Intensive Care Med 30:6 (2004), 1117–1121.
28. 28 De Jonghe, B., Bastuji-Garin, S., Durand, M.C., et al. Respiratory weakness is associated with limb weakness and delayed weaning in critical illness. Crit Care Med 35:9 (2007), 2007–2015.
29. 29 Hermans, G., Van Mechelen, H., Clerckx, B., et al. Acute outcomes and 1-year mortality of intensive care unit-acquired weakness: a cohort study and propensity-matched analysis. Am J Respir Crit Care Med 190:4 (2014), 410–420.
30. 30 TEAM Study Investigators, Hodgson, C., Bellomo, R., et al. Early mobilization and recovery in mechanically ventilated patients in the ICU: a bi-national, multi-centre, prospective cohort study. Crit Care, 19, 2015, 81.
31. 31 Wieske, L., Dettling-Ihnenfeldt, D.S., Verhamme, C., et al. Impact of ICU-acquired weakness on post-ICU physical functioning: a follow-up study. Crit Care, 19, 2015, 196.
32. 32 Herridge, M.S., Cheung, A.M., Tansey, C.M., et al. One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med 348:8 (2003), 683–693.
33. 33 Herridge, M.S., Tansey, C.M., Matté, A., et al. Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med 364:14 (2011), 1293–1304.
34. 34 Sricharoenchai, T., Parker, A.M., Zanni, J.M., Nelliot, A., Dinglas, V.D., Needham, D.M., Safety of physical therapy interventions in critically ill patients: a single-center prospective evaluation of 1110 intensive care unit admissions. J Crit Care 29:3 (2014), 395–400.
35. 35 Zafiropoulos, B., Alison, J.A., McCarren, B., Physiological responses to the early mobilisation of the intubated, ventilated abdominal surgery patient. Aust J Physiother 50:2 (2004), 95–100.
36. 36 Zanni, J.M., Korupolu, R., Fan, E., et al. Rehabilitation therapy and outcomes in acute respiratory failure: an observational pilot project. J Crit Care 25:2 (2010), 254–262.
37. 37 Sommers, J., Engelbert, R.H., Dettling-Ihnenfeldt, D., et al. Physiotherapy in the intensive care unit: an evidence-based, expert driven, practical statement and rehabilitation recommendations. Clin Rehabil 29:11 (2015), 1051–1063.
38. 38 Hodgson, C.L., Stiller, K., Needham, D.M., et al. Expert consensus and recommendations on safety criteria for active mobilization of mechanically ventilated critically ill adults. Crit Care, 18(6), 2014, 658.
39. 39 Hanekom, S., Gosselink, R., Dean, E., et al. The development of a clinical management algorithm for early physical activity and mobilization of critically ill patients: synthesis of evidence and expert opinion and its translation into practice. Clin Rehabil 25:9 (2011), 771–787.
40. 40 Morris, P.E., Goad, A., Thompson, C., et al. Early intensive care unit mobility therapy in the treatment of acute respiratory failure. Crit Care Med 36:8 (2008), 2238–2243.
41. 41 Schweickert, W.D., Pohlman, M.C., Pohlman, A.S., et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet 373:9678 (2009), 1874–1882.
42. 42 Burtin, C., Clerckx, B., Robbeets, C., et al. Early exercise in critically ill patients enhances short-term functional recovery. Crit Care Med 37:9 (2009), 2499–2505.
43. 43 Routsi, C., Gerovasili, V., Vasileiadis, I., et al. Electrical muscle stimulation prevents critical illness polyneuromyopathy: a randomized parallel intervention trial. Crit Care, 14(2), 2010, R74.
44. 44 Denehy, L., Skinner, E.H., Edbrooke, L., et al. Exercise rehabilitation for patients with critical illness: a randomized controlled trial with 12 months of follow-up. Crit Care, 17(4), 2013, R156.
45. 45 Moss M, Nordon-Craft A, Malone D, et al. A randomized trial of an intensive physical therapy program for acute respiratory failure patients. Am J Respir Crit Care Med. In press.
46. 46 Berney, S., Haines, K., Skinner, E.H., Denehy, L., Safety and feasibility of an exercise prescription approach to rehabilitation across the continuum of care for survivors of critical illness. Phys Ther 92:12 (2012), 1524–1535.
47. 47 Parker, A., Tehranchi, K.M., Needham, D.M., Critical care rehabilitation trials: the importance of “usual care.”. Crit Care, 17(5), 2013, 183.
48. 48 Needham, D.M., Korupolu, R., Zanni, J.M., et al. Early physical medicine and rehabilitation for patients with acute respiratory failure: a quality improvement project. Arch Phys Med Rehabil 91:4 (2010), 536–542.
49. 49 Needham, D.M., Korupolu, R., Rehabilitation quality improvement in an intensive care unit setting: implementation of a quality improvement model. Top Stroke Rehabil 17:4 (2010), 271–281.
50. 50 Pronovost, P.J., Berenholtz, S.M., Needham, D.M., Translating evidence into practice: a model for large scale knowledge translation. BMJ, 337, 2008, a1714.
51. 51 Engel, H.J., Tatebe, S., Alonzo, P.B., Mustille, R.L., Rivera, M.J., Physical therapist-established intensive care unit early mobilization program: quality improvement project for critical care at the University of California San Francisco Medical Center. Phys Ther 93:7 (2013), 975–985.
52. 52 Clark, D.E., Lowman, J.D., Griffin, R.L., Matthews, H.M., Reiff, D.A., Effectiveness of an early mobilization protocol in a trauma and burns intensive care unit: a retrospective cohort study. Phys Ther 93:2 (2013), 186–196.
53. 53 McWilliams, D., Weblin, J., Atkins, G., et al. Enhancing rehabilitation of mechanically ventilated patients in the intensive care unit: a quality improvement project. J Crit Care 30:1 (2015), 13–18.
54. 54 Engel, H.J., Needham, D.M., Morris, P.E., Gropper, M.A., ICU early mobilization: from recommendation to implementation at three medical centers. Crit Care Med 41:9 suppl 1 (2013), S69–S80.
55. 55 Dubb R, Nydahl P, Hermes C, et al. Barriers and strategies for early mobilization in the ICU: a narrative review. Ann Am Thorac Soc. In press.
56. 56 Bakhru, R.N., Wiebe, D.J., McWilliams, D.J., Spuhler, V.J., Schweickert, W.D., An environmental scan for early mobilization practices in U.S. ICUs. Crit Care Med 43:11 (2015), 2360–2369.
57. 57 Leditschke, I.A., Green, M., Irvine, J., Bissett, B., Mitchell, I.A., What are the barriers to mobilizing intensive care patients?. Cardiopulm Phys Ther J 23:1 (2012), 26–29.
58. 58 Hopkins, R.O., Spuhler, V.J., Thomsen, G.E., Transforming ICU culture to facilitate early mobility. Crit Care Clin 23:1 (2007), 81–96.
59. 59 Thomsen, G.E., Snow, G.L., Rodriguez, L., Hopkins, R.O., Patients with respiratory failure increase ambulation after transfer to an intensive care unit where early activity is a priority. Crit Care Med 36:4 (2008), 1119–1124.
60. 60 Hopkins, R.O., Spuhler, V.J., Strategies for promoting early activity in critically ill mechanically ventilated patients. AACN Adv Crit Care 20:3 (2009), 277–289.
61. 61 Dinglas, V.D., Parker, A.M., Reddy, D.R.S., et al. A quality improvement project sustainably decreased time to onset of active physical therapy intervention in patients with acute lung injury. Ann Am Thorac Soc 11:8 (2014), 1230–1238.
62. 62 Eakin, M.N., Ugbah, L., Arnautovic, T., Parker, A.M., Needham, D.M., Implementing and sustaining an early rehabilitation program in a medical intensive care unit: a qualitative analysis. J Crit Care 30:4 (2015), 698–704.
63. 63 Mendez-Tellez, P.A., Dinglas, V.D., Colantuoni, E., et al. Factors associated with timing of initiation of physical therapy in patients with acute lung injury. J Crit Care 28:6 (2013), 980–984.
64. 64 Dinglas, V.D., Colantuoni, E., Ciesla, N., Mendez-Tellez, P.A., Shanholtz, C., Needham, D.M., Occupational therapy for patients with acute lung injury: factors associated with time to first intervention in the intensive care unit. Am J Occup Ther 67:3 (2013), 355–362.
65. 65 Morandi, A., Brummel, N.E., Ely, E.W., Sedation, delirium and mechanical ventilation: the “ABCDE” approach. Curr Opin Crit Care 17:1 (2011), 43–49.
66. 66 Balas, M.C., Vasilevskis, E.E., Olsen, K.M., et al. Effectiveness and safety of the awakening and breathing coordination, delirium monitoring/management, and early exercise/mobility bundle. Crit Care Med 42:5 (2014), 1024–1036.
67. 67 Vasilevskis, E.E., Ely, E.W., Speroff, T., Pun, B.T., Boehm, L., Dittus, R.S., Reducing iatrogenic risks: ICU-acquired delirium and weakness—crossing the quality chasm. Chest 138:5 (2010), 1224–1233.
68. 68 ICU Liberation website. http://www.iculiberation.org/Pages/default.aspx. Accessed April 1, 2016.
69. 69 Pohlman, M.C., Schweickert, W.D., Pohlman, A.S., et al. Feasibility of physical and occupational therapy beginning from initiation of mechanical ventilation. Crit Care Med 38:11 (2010), 2089–2094.
70. 70 Damluji, A., Zanni, J.M., Mantheiy, E., Colantuoni, E., Kho, M.E., Needham, D.M., Safety and feasibility of femoral catheters during physical rehabilitation in the intensive care unit. J Crit Care 28:4 (2013), 535.e9–535.e15.
71. 71 Perme, C., Lettvin, C., Throckmorton, T.A., Mitchell, K., Masud, F., Early mobility and walking for patients with femoral arterial catheters in intensive care unit: a case series. J Acute Care Phys Ther 2:1 (2011), 32–36.
72. 72 Perme, C., Nalty, T., Winkelman, C., Kenji Nawa, R., Masud, F., Safety and efficacy of mobility interventions in patients with femoral catheters in the ICU: a prospective observational study. Cardiopulm Phys Ther J 24:2 (2013), 12–17.
73. 73 Toonstra AL, Zanni JM, Sperati C, et al. Feasibility and safety of physical therapy during continuous renal replacement therapy in the intensive care unit. Ann Am Thorac Soc. In press.
74. 74 Wang, Y.T., Haines, T.P., Ritchie, P., et al. Early mobilization on continuous renal replacement therapy is safe and may improve filter life. Crit Care, 18(4), 2014, R161.
75. 75 Morris, P.E., Griffin, L., Berry, M., et al. Receiving early mobility during an intensive care unit admission is a predictor of improved outcomes in acute respiratory failure. Am J Med Sci 341:5 (2011), 373–377.
76. 76 Lord, R.K., Mayhew, C.R., Korupolu, R., et al. ICU early physical rehabilitation programs: financial modeling of cost savings. Crit Care Med 41:3 (2013), 717–724.
77. 77 Needham, D.M., Truong, A.D., Fan, E., Technology to enhance physical rehabilitation of critically ill patients. Crit Care Med 37:10 suppl (2009), S436–S441.
78. 78 Kho, M.E., Truong, A.D., Zanni, J.M., et al. Neuromuscular electrical stimulation in mechanically ventilated patients: a randomized, sham-controlled pilot trial with blinded outcome assessment. J Crit Care 30:1 (2015), 32–39.
79. 79 Parry, S.M., Berney, S., Granger, C.L., Koopman, R., El-Ansary, D., Denehy, L., Electrical muscle stimulation in the intensive care setting: a systematic review. Crit Care Med 41:10 (2013), 2406–2418.
80. 80 Wageck, B., Nunes, G.S., Silva, F.L., Damasceno, M.C.P., de Noronha, M., Application and effects of neuromuscular electrical stimulation in critically ill patients: systematic review. Med Intensiva Soc Esp Med Intensiva Unidades Coronarias 38:7 (2014), 444–454.
81. 81 Williams, N., Flynn, M., A review of the efficacy of neuromuscular electrical stimulation in critically ill patients. Physiother Theory Pract 30:1 (2014), 6–11.
82. 82 Truong AD, Kho ME, Brower RG, Feldman DR, Colantuoni E, Needham DM. Effects of neuromuscular electrical stimulation on cytokines in peripheral blood for healthy participants: a prospective, single-blinded study [published online ahead of print October 16, 2015]. Clin Physiol Funct Imaging. http://dx.doi.org/10.1111/cpf.12290.
83. 83 Kho, M.E., Martin, R.A., Toonstra, A.L., et al. Feasibility and safety of in-bed cycling for physical rehabilitation in the intensive care unit. J Crit Care 30:6 (2015), 1419.e1–1419.e5.
84. 84 Parry, S.M., Berney, S., Warrillow, S., et al. Functional electrical stimulation with cycling in the critically ill: a pilot case-matched control study. J Crit Care 29:4 (2014), 695.e1–695.e7.
85. 85 Kho, M.E., Damluji, A., Zanni, J.M., Needham, D.M., Feasibility and observed safety of interactive video games for physical rehabilitation in the intensive care unit: a case series. J Crit Care 27:2 (2012), 219.e1–219.e6.
86. 86 Felten-Barentsz, K.M., Haans, A.J.C., Slutsky, A.S., Heunks, L.M.A., van der Hoeven, J.G., Feasibility and safety of hydrotherapy in critically ill ventilated patients. Am J Respir Crit Care Med 191:4 (2015), 476–477.