Biodegradable hydrophilic carriers for the oral delivery of hematological factor IX for hemophilia B treatment

International Journal of Pharmaceutics

Volumn 514, Issue 1, 2016, Pages 220-228

  Horava, Sarena D ^a,b   Moy, Katie J ^a,b   Peppas, Nicholas A ^a,b,c  

^a The University of Texas at Austin   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Biodegradable polymer; Coagulation factor IX; Drug delivery; Hydrogels

Indexed keywords

BLOOD CLOTTING FACTOR 9; DRUG CARRIER; MACROGOL; POLYMETHACRYLIC ACID; TRYPSIN; BIODEGRADABLE PLASTIC; EXCIPIENT; HYDROGEL; MACROGOL DERIVATIVE; PEPTIDE; POLY(METHACRYLIC ACID-ETHYLENE GLYCOL); POLYMER; POLYMETHACRYLIC ACID DERIVATIVE;

ARTICLE; BIODEGRADABILITY; CONTROLLED STUDY; CROSS LINKING; DRUG DELIVERY SYSTEM; DRUG RELEASE; ENZYMATIC DEGRADATION; HEMOPHILIA B; HUMAN; HUMAN CELL; HYDROGEL; IN VITRO STUDY; INFRARED SPECTROSCOPY; PH; POLYMERIZATION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TURBIDIMETRY; CHEMICAL PHENOMENA; CHEMISTRY; HT-29 CELL LINE; ORAL DRUG ADMINISTRATION; TUMOR CELL LINE;

ADMINISTRATION, ORAL; BIODEGRADABLE PLASTICS; CELL LINE, TUMOR; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; EXCIPIENTS; FACTOR IX; HEMOPHILIA B; HT29 CELLS; HUMANS; HYDROGEL; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; PEPTIDES; POLYETHYLENE GLYCOLS; POLYMERS; POLYMETHACRYLIC ACIDS;

EID: 84995553526     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2016.05.056     Document Type: Article

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