Hierarchical zwitterionic modification of a SERS substrate enables real-time drug monitoring in blood plasma

Nature Communications

Volumn 7, Issue , 2016, Pages

  Sun, Fang ^a   Hung, Hsiang Chieh ^a   Sinclair, Andrew ^a   Zhang, Peng ^a   Bai, Tao ^a   Galvan, Daniel David ^a   Jain, Priyesh ^a   Li, Bowen ^b   Jiang, Shaoyi ^a,b   Yu, Qiuming ^a  

^a University of Washington   (United States)

^b University of Washington   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (3 METHYLAMINOPROPYLAMINO) 1 PROPANETHIOL; 3 MERCAPTOPROPIONIC ACID; AMITRIPTYLINE; CARBAMAZEPINE; DOXORUBICIN; FRUCTOSE; GOLD; PHENYTOIN; PLASMA PROTEIN; POLY(CARBOXYBETAINE ACRYLAMIDE); POLYMER; SELF ASSEMBLED MONOLAYER; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; DRUG;

ADSORPTION; ANALYTICAL METHOD; BLOOD; CONCENTRATION (COMPOSITION); DRUG; GOLD; PROBE; PROTEIN; RAMAN SPECTROSCOPY; SUBSTRATE;

ARTICLE; ATOM TRANSFER RADICAL POLYMERIZATION; BLOOD ANALYSIS; BLOOD PH; CHEMICAL MODIFICATION; CLINICAL EFFECTIVENESS; CONCENTRATION PROCESS; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG MONITORING; HIERARCHICAL ZWITTERIONIC MODIFICATION; HUMAN; MATERIAL COATING; MOLECULAR DYNAMICS; PHYSICAL CHEMISTRY; PLASMA PROTEIN BINDING; PROTEIN ANALYSIS; QUANTITATIVE ANALYSIS; RAMAN SPECTROMETRY; RESPONSE TIME; SENSITIVITY ANALYSIS; SURFACE PROPERTY; BLOOD; GENETIC PROCEDURES; PROCEDURES;

BIOSENSING TECHNIQUES; DRUG MONITORING; HUMANS; PHARMACEUTICAL PREPARATIONS; SPECTRUM ANALYSIS, RAMAN;

EID: 84995519450     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms13437     Document Type: Article

References (43)

1. Ghiculescu, R. Therapeutic drug monitoring: which drugs, why, when and how to do it. Aust. Prescr. 31, 42-44 (2008).
2. Bantz, K. C. et al. Recent progress in SERS biosensing. Phys. Chem. Chem. Phys. 13, 11551-11567 (2011).
3. Anker, J. N. et al. Biosensing with plasmonic nanosensors. Nat. Mater. 7, 442-453 (2008).
4. Anema, J. R., Li, J. F., Yang, Z. L., Ren, B. & Tian, Z. Q. Shell-isolated nanoparticle-enhanced Raman spectroscopy: expanding the versatility of surface-enhanced Raman scattering. Annu. Rev. Anal. Chem. 4, 129-150 (2011).
5. Kneipp, J., Kneipp, H., Wittig, B. & Kneipp, K. Novel optical nanosensors for probing and imaging live cells. Nanomed. Nanotechnol. 6, 214-226 (2010).
6. Cao, Y. W. C., Jin, R. C. & Mirkin, C. A. Nanoparticles with Raman spectroscopic fingerprints for DNA and RNA detection. Science 297, 1536-1540 (2002).
7. Qian, X. M. et al. In vivo tumor targeting and spectroscopic detection with surface-enhanced Raman nanoparticle tags. Nat. Biotechnol. 26, 83-90 (2008).
8. Taylor, R. D., MacCoss, M. & Lawson, A. D. G. Rings in drugs. J. Med. Chem. 57, 5845-5859 (2014).
9. Farquharson, S., Shende, C., Sengupta, A., Huang, H. & Inscore, F. Rapid detection and identification of overdose drugs in saliva by surface-enhanced Raman scattering using fused gold colloids. Pharmaceutics 3, 425-439 (2011).
10. Trachta, G., Schwarze, B., Sagmuller, B., Brehm, G. & Schneider, S. Combination of high-performance liquid chromatography and SERS detection applied to the analysis of drugs in human blood and urine. J. Mol. Struct. 693, 175-185 (2004).
11. Andreou, C., Hoonejani, M. R., Barmi, M. R., Moskovits, M. & Meinhart, C. D. Rapid detection of drugs of abuse in saliva using surface enhanced Raman spectroscopy and microfluidics. ACS Nano 7, 7157-7164 (2013).
12. Bonifacio, A., Cervo, S. & Sergo, V. Label-free surface-enhanced Raman spectroscopy of biofluids: fundamental aspects and diagnostic applications. Anal. Bioanal. Chem. 407, 8265-8277 (2015).
13. Schlucker, S. Surface-enhanced Raman spectroscopy: concepts and chemical applications. Angew. Chem. Int. Ed. 53, 4756-4795 (2014).
14. Moskovits, M. Surface-enhanced Raman spectroscopy: a brief retrospective. J. Raman Spectrosc. 36, 485-496 (2005).
15. Bonifacio, A. et al. Surface-enhanced Raman spectroscopy of blood plasma and serum using Ag and Au nanoparticles: a systematic study. Anal. Bioanal. Chem. 406, 2355-2365 (2014).
16. Stosch, R., Henrion, A., Schiel, D. & Guttler, B. Surface enhanced Raman scattering based approach for quantitative determination of creatinine in human serum. Anal. Chem. 77, 7386-7392 (2005).
17. Jiang, S. Y. & Cao, Z. Q. Ultralow-fouling, functionalizable, and hydrolyzable zwitterionic materials and their derivatives for biological applications. Adv. Mater. 22, 920-932 (2010).
18. Bai, T. et al. Restraint of the differentiation of mesenchymal stem cells by a nonfouling zwitterionic hydrogel. Angew. Chem. Int. Ed. 53, 12729-12734 (2014).
19. Keefe, A. J. & Jiang, S. Y. Poly(zwitterionic)protein conjugates offer increased stability without sacrificing binding affinity or bioactivity. Nat. Chem. 4, 60-64 (2012).
20. Zhang, P. et al. Zwitterionic gel encapsulation promotes protein stability, enhances pharmacokinetics, and reduces immunogenicity. Proc. Natl Acad. Sci. USA 112, 12046-12051 (2015).
21. Pristinski, D., Tan, S. L., Erol, M., Du, H. & Sukhishvili, S. In situ SERS study of Rhodamine 6G adsorbed on individually immobilized Ag nanoparticles. J. Raman Spectrosc. 37, 762-770 (2006).
22. Lin, D. et al. Label-free blood plasma test based on surface-enhanced Raman scattering for tumor stages detection in nasopharyngeal cancer. Sci. Rep. 4, 4751 (2014).
23. Rycenga, M., McLellan, J. M. & Xia, Y. N. A SERS study of the molecular structure of alkanethiol monolayers on Ag nanocubes in the presence of aqueous glucose. Chem. Phys. Lett. 463, 166-171 (2008).
24. Kurouski, D., Postiglione, T., Deckert-Gaudig, T., Deckert, V. & Lednev, I. K. Amide I vibrational mode suppression in surface (SERS) and tip (TERS) enhanced Raman spectra of protein specimens. Analyst 138, 1665-1673 (2013).
25. Harder, P., Grunze, M., Dahint, R., Whitesides, G. M. & Laibinis, P. E. Molecular conformation in oligo(ethylene glycol)-terminated self-assembled monolayers on gold and silver surfaces determines their ability to resist protein adsorption. J. Phys. Chem. B 102, 426-436 (1998).
26. Ferguson, B. S. et al. Real-time, aptamer-based tracking of circulating therapeutic agents in living animals. Sci. Transl. Med. 5, 213ra165 (2013).
27. Desoize, B. & Robert, J. Individual dose adaptation of anticancer drugs. Eur. J. Cancer 30A, 844-851 (1994).
28. Wright, J. D., Boudinot, F. D. & Ujhelyi, M. R. Measurement and analysis of unbound drug concentrations. Clin. Pharmacokinet. 30, 445-462 (1996).
29. 2+ ions and drug release from SPION-based nanocarriers. Analyst 138, 7354-7361 (2013).
30. Chassany, O., Urien, S., Claudepierre, P., Bastian, G. & Tillement, J. P. Comparative serum protein binding of anthracycline derivatives. Cancer Chemother. Pharmacol. 38, 571-573 (1996).
31. Nieciecka, D. & Krysinski, P. Interactions of doxorubicin with self-assembled monolayer-modified electrodes: electrochemical, surface plasmon resonance (SPR), and gravimetric studies. Langmuir 27, 1100-1107 (2011).
32. Tawde, S. R., Mukesh, D., Yakhmi, J. V. & Manohar, C. Dye adsorption on self-assembled silane monolayers: optical absorption and modeling. J. Mater. Chem. 9, 1847-1851 (1999).
33. Preskorn, S. H., Dorey, R. C. & Jerkovich, G. S. Therapeutic drug-monitoring of tricyclic antidepressants. Clin. Chem. 34, 822-828 (1988).
34. Shakya, G., Mala, S., Shakya, K. N. & Shrestha, R. Therapeutic drug monitoring of antiepileptic drugs. J. Nepal Med. Assoc. 47, 94-97 (2008).
35. Goldman, L. & Schafer, A. I. Goldman-Cecil Medicine 25th Edn pp 2712-2722 (Elsevier, 2015).
36. Alvarez-Puebla, R. A. & Liz-Marzan, L. M. SERS detection of small inorganic molecules and ions. Angew. Chem. Int. Ed. 51, 11214-11223 (2012).
37. Sun, F. et al. Sensitive and fast detection of fructose in complex media via symmetry breaking and signal amplification using surface-enhanced Raman spectroscopy. Anal. Chem. 86, 2387-2394 (2014).
38. Hinderling, P. H. & Hartmann, D. The pH dependency of the binding of drugs to plasma proteins in man. Ther. Drug Monit. 27, 71-85 (2005).
39. Sun, F. et al. Functionalized plasmonic nanostructure arrays for direct and accurate mapping extracellular pH of living cells in complex media using SERS. Biosensors Bioelectron. 73, 202-207 (2015).
40. Wang, F. L. et al. Surface-enhanced Raman scattering detection of pH with silica-encapsulated 4-mercaptobenzoic acid-functionalized silver nanoparticles. Anal. Chem. 84, 8013-8019 (2012).
41. Sun, F. et al. Stealth surface modification of surface-enhanced Raman scattering substrates for sensitive and accurate detection in protein solutions. ACS Nano 9, 2668-2676 (2015).
42. Yu, Q. M., Guan, P., Qin, D., Golden, G. & Wallace, P. M. Inverted size-dependence of surface-enhanced Raman scattering on gold nanohole and nanodisk arrays. Nano Lett. 8, 1923-1928 (2008).
43. Zhang, Z. et al. Nonfouling behavior of polycarboxybetaine-grafted surfaces: structural and environmental effects. Biomacromolecules 9, 2686-2692 (2008).